MCQS IN AMYLOIDOSIS FROM 2004 TO 2014 PREPQRED BY DR. HAMZA KHEDERAMYLOIDOSIS 1.Familial Mediterranean fever is associated with precursor protein: (2013) a}immunoglobulin. b)B2 microglobulin. CJATTR. (ayaa. 2.AB is the main component of amyloid plaques except in: (2013) a)Alzheimer's disease. b)Lewy body dementia. €)Cerebral amyloid angiopathy. @hronic rheumatoid arthritis. 3.amyloid plaques deposit extracellularly except in : (2013) a)Alzheimer's disease. BjLewy body dementia. c}inclusion body myositis (a muscle disease ). ¢)Cerebral amyloid angiopathy. 4.Which of the following statement is not true for amyloidosis: (18-6-2011) a)It is made up predominantly of fibrillary protein. b)Itis deposited in the wall of blood vessels. @Budan IM and osmic acid can stain amyloid specifically. 4) can lead to nephrotic syndrome. 5.Regarding amyloidosis which statement is incorrect: (18-6-201 1 a)Appears as extracellular basophilic hyaline material, b)Can be stained with Congo red dye. ©)Show an apple green birefringence in polarized light . @)ls a complication of medullary carcinoma of the thyroid, spdh tye a{ 6.1n amyloidosis the abnormal protein deposited (29-48-2010) a)lntracellular b) Pixtracellutar ©)Nuclear dC toplasmic 7.M' iple myeloma the abnormal protein deposited is: (29-48-2010 Quiz 2009 (2008) (Amyloid light chain b)Serum amyloid-associated protein, ©)Beta -2+ microglobulin, d) All of the above #.Commonest cause of death in primary amyloidosis is; (294-2010) (a)Renal failure b)Liver involvement ‘Bleeding diathesis, )Respiratory failure 9.The green brifrigence of amyloid protein is due to NSI5120~ —— Quiz2009) (2008) (a)Croas B pleated confirn b) Amyloid fibril ©) P component d)None of the above, (x) 10.These are the feature of sago spleen except : (2008) (Quiz 2009) a)lt is moderately enlarged. b)It is common )There is focal Amyloid deposit in the wall of the central arterioles. (d)There is diffuse Amyloid deposit in the wall of the sinusoids. Q NAB prrderd as MAPA) DH0K, (AY - Maeaatel Raa Decent UB) 15. egegpve d AANA e CO Drawn Maeroscanerhy® Laas sedine up) - 6 a sole Yeisen: conga bye 0ions lead to amyloidosis of the AA type except : ( Quiz 20092006) a)Rheumatoid arthritis. @piaemodialysis in chronic renal failure. ©)Bronchiectasis. d)Familial Mediterranean fever. 12.Which of the following diseases is associated with increased Production of amyloid light chain (AL) protein ? (2008) )Rheumatoid arthritis. b)Aplastic anemia Chronic abscess. CpPiasma cell tumor. 13.1n multiple myeloma the abnormal protein deposited (Quiz 2009) a)Serum amyloid-associated protein b)Beta -2-microglobulin ©)AIl of above. @Non of the above. 14.1n amyloidosis the special stain used is : (Quiz. 2009) 8) Brussian blue. b)Methylene blue. 25/B/rH08 Congo red. )PAS stain. 15.In amyloidosis the gross staining used is: (Quiz 2009) a) Brussian blue. (Ppugol's iodine. Congo red. 4)PAS stain, 16.The following condition leads to amyloidosis of the AB2M type: (19-7-2009) b)Familial Mediterranean fever. 4) Non of the above. Dtlacmodialysis in chronic renal failure ¢)AIl of the above . web Hae a17.The following are cause of amyloidosis ,Except (2008) a)Chronic 1.B b)Rhaumatoid arthritis. OW ial hepatitis d)Multiple myeloma. 18.Amyloid reacts with the following stains , Except: (2000) a) Congo red. b)Thioflavine -T ¢) Methyl violet djPrussian blue 19.Late amyloidosis of these organs lead to their enlargement sExcept: (2006) a)Heart. b)Liver. )Spleen, (@kidney 20.Amyloid material is of the AA in amyloidosis due to the following , Except : (7-2006) a)Chronic pulmonary tuberculosis (Berronic: renal failure with haemodialysis. c)Familial Mediterranean fever. d)Hodgkin's disease. < 21.Amyloidosis material is of the AA type in : (2005) Ca} Familial Mediterranean fever. b)Primary systemic amyloidosis. c) Chronic renal failure with haemodialysis. d)Alzheimer’s disease. ws) Qe Ms acct Ferre ab ow amber dods XR. 1414 [204 (B- & AL PARE Mra, Commrcades Aneamadridh adds B- cccuvs Mabou SZ Aoi E manda marae Ce Mans Magrosed ba etrah bio ae Dok AA AAR ann Camdseke Anmrure odreapnael es seaydh Bas22. Amyloidosis material can be detected microscopically by usin: (2004) a)Congo red stain. _b)Thioflavine ~T. c)PAS stain. \ dJAII of the above 23.The following conditions are particularly associated with the deposition of amyloid , Except : VEIN tent (2004) SNSSB/ OND a)Leprosy b)Chronic osteomyelitis . ©)Type Il diabetes @Pneumococcal pneumonia 24,Primary amyloidosis occurs in : (2004) a)Chronic inflammation. (BMultiple myeloma. ©)Viral infection d)Rheumatoid arthritis. 25.The amyloid in Alzheimer's disease is as. b)AA. ©)B2 microglobulin 4)None of the above . 26.Which of the following statements is not true for amyloidosis : a)It is made up predominantly of fibrillary protein . b)It is deposited in the walls of blood vessels (Co)Sudan II1 and osmic acid can stain amyloid specifically <* d)It can lead to nephrotic syndrome . 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