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REFLECTION

Fever is elevated body temperature (> 37.8° C orally or > 38.2° C


rectally) or an elevation above a person’s known normal daily value. Fever
occurs when the body's thermostat (located in the hypothalamus) resets at
a higher temperature, primarily in response to an infection. Elevated body
temperature that is not caused by a resetting of the temperature set point is
called hyperthermia. Many patients use “fever” very loosely, often meaning
that they feel too warm, too cold, or sweaty, but they have not actually
measured their temperature.
A fever fights infection by helping immune cells to crawl along blood-
vessel walls to attack invading microbes. Turn up the heat in the body, and
that speeds up many body processes, including our immune response. We’ll
find out exactly what’s happening in the body when get feverish chills . When
immune cells detect an infectious organism, they produce fever-making
chemicals.These chemicals prompt the body to produce prostaglandins,
which turn up the thermostat in the brain. Let’s say prostaglandins reset the
thermostat to 102 degrees. The body works hard to raise its temperature, but
in the meantime, you get the chills. Whenever the thermostat in the brain is
set above your actual body temperature, you feel chilly. As soon as your body
temperature rises to match the thermostat at 102, the chills will stop.
Researchers from Roswell Park Cancer Institute found that a higher body
temperature can help our immune systems to work better and harder against
infected cells. Having a fever might be uncomfortable, but this research report
and several others are showing that having a fever is part of an effective
immune response. But new work also suggests that the immune system
might be temporarily enhanced functionally when our temperatures rise with
fever.

REFERENCES:
https://www.merckmanuals.com/professional/infectious-diseases/biology of-
infectious-disease/fever
https://indianapublicmedia.org/amomentofscience/anatomy-of-a-fever/
https://www.huffpost.com/entry/fever-immune-system-cells_n_1074445

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