You are on page 1of 6

RESTORATIVE DENTISTRY

Flexural strength of minimum thickness ceramic veneers


manufactured with different techniques
Fabio A. P. Rizzante, DDS, MSc, PhD/Idiane B. L. Soares-Rusu/Suellen S. Senna, DDS/
Carla M. Ramos-Tonello, DDS, MSc, PhD/Rafael F. L. Mondelli, DDS, MSc, PhD/Sérgio K. Ishikiriama, DDS, MSc, PhD/
Ana Flávia S. Borges, DDS, MSc, PhD/Zvi Gutmacher, DMD

The objective of the present study was to assess ture. Fractured samples were analyzed under stereomicro-
the effect of monolithic and bilayer restorations considering scope and SEM. Flexural strength data were analyzed by
heat-pressed and milled/CAD/CAM reinforced lithium disili- one-way ANOVA and Tukey test. Results: The control group
cate ceramic veneers, on the flexural strength after cementa- showed the highest flexural strength results (119.57 ±
tion. Method and materials: Thirty-five specimens were di- 19.49 MPa), with values similar to groups HPM (98 ± 25.62 MPa)
vided into five groups (n = 7), according to the restorative and CCM (96.14 ± 20.60 MPa). Groups HPB and CCB showed
solution: 2-mm thickness composite resin (CR2); heat-pressed lower values when compared with the other groups. Fracture
monolithic ceramic 0.6 mm (HPM), CAD/CAM monolithic started from the base on monolithic groups and from ceramic
ceramics 0.6 mm (CCM); heat-pressed monolithic ceramic on bilayer groups. Conclusion: Both ceramic systems (CAD/
0.4 mm + 0.2 mm glass-ceramic (HPB); CAD/CAM monolithic CAM and heat-pressed) have similar fracture strength, al-
ceramic 0.4 mm + 0.2 glass-ceramic (CCB). Specimens were though bilayer restorations present lower strength when com-
cemented on composite resin bars and submitted to a three- pared with monolithic ceramics. (Quintessence Int 2020;51:
point bending test on a Universal Testing Machine, until frac- 268–273; doi: 10.3290/j.qi.a44147)

Key words: CAD/CAM, ceramics, dental materials, esthetics, operative dentistry, prosthodontics, veneers

The “perfect” smile has become essential, frequently associated E-max Press, Ivoclar Vivadent) and computer-aided de-
with better social and professional projection. Ceramic veneers sign/computer-assisted manufacture (CAD/CAM) tech-
are one of the possible treatments for predictable resolutions of niques (eg, IPS E-max CAD, Ivoclar Vivadent).10-12 CAD/CAM
esthetic cases, allowing excellent esthetic results while preserving systems allow restoration manufacturing in reduced time
as much as possible of teeth structure, which is consistent with while reducing production costs.10,13 It has been speculated
the concepts of a minimally invasive dentistry.1-3 Ceramic veneers that due to better process standardization (less technically
are considered a well-established treatment option, with longev- sensitive), they could achieve higher flexural strength val-
ity of 100% after two years4 and around 90% after over 10 years.5,6 ues.14 Nevertheless, this assumption seems controversial since
Due to their physico-mechanical and optical properties, IPS E-max CAD goes through two crystallization processes (one
lithium disilicate ceramics are one of the most frequently during the manufacturing process – lithium metasilicate/Li2SiO3,
used material for ceramic veneers, allowing very conservative and a second one in the laboratory/clinic – lithium disilicate/
preparations.7-9 In some cases, the marginal edges can be Li2Si2O5), resulting in reduced mechanical properties due to a
defined as a feather edge (about 0.3-mm thickness) or even random distribution of the crystals, and their smaller size when
with no reduction of tooth structures at all.4 compared with pressed lithium disilicate ceramics.11,12,15,16
This class of ceramics are extremely versatile, allowing mono- Regarding the number of layers, bilayered ceramics (associ-
lithic or bilayer restorations, using both heat-pressed (eg, IPS ation between lithium disilicate and a feldspathic or nanofluor-

268 QUINTESSENCE INTERNATIONAL | volume 51 • number 4 • April 2020


Rizzante et al

apatite ceramic) were designed to improve esthetics.9 None- the metal base, followed by cuts parallel to the block long axis
theless, this restorative solution is associated with higher failure (three slices of 4 mm each), resulting in three smaller blocks
rates.9,10,15 This said, monolithic restorations usually are associ- (16 × 4 × 12 mm). Each block was cut again through its long
ated with higher flexural strength and success rates.10,14 axis resulting in blocks of 16 × 4 × 0.4 mm or 0.6 mm. CAD/
Considering these aspects, there is a lack of information CAM specimens were crystallized in a ceramic furnace (Ivoclar
about flexural strength of minimally invasive veneers made 3000, Ivoclar Vivadent), using program 81 (850°C for 25 min-
with different techniques. The aim of the present study was to utes), in accordance with manufacturers’ recommendations.
assess the effect of heat-pressed and CAD/CAM reinforced lith- After thickness standardization, glass-ceramic was applied
ium disilicate ceramic veneers, considering monolithic or over the core/base ceramic, in groups HPB and CCB. For this,
bilayer restorations, on the flexural strength after cementation. the 0.4-mm samples were positioned into the metallic matrix,
with a 1.4-mm shim, and a 0.2-mm veneer layer was applied
The null hypotheses tested were: and heated on a ceramic furnace (Vulcano, EDG; initial tem-
■ there would be no difference in flexural strength for mono- perature 430°C, final temperature 730°C, with approximately
lithic lithium disilicate ceramics between CAD/CAM and 30 minutes cycle time).
heat-press techniques Resin bases of 16 × 4 × 2 mm (Z350XT, 3M ESPE) were ob-
■ there would be no difference in flexural strength of bilayer tained with the aid of the metallic matrix, without shim inter-
lithium disilicate ceramics between CAD/CAM and for heat- position. After composite insertion, a mylar strip was pos-
press techniques itioned and pressed over the surface with a glass plate to
■ there would be no difference in the flexural strength between standardize the surface. After glass plate removal, composite
monolithic and bilayer lithium disilicate ceramics veneers. was light cured with a 1,200 mW/cm2 LED (Radical, SDI) at three
points, for 40 seconds, on both upper and lower surfaces
(240 seconds in total).
Method and materials
For the cementation protocol, the ceramics were etched
Thirty-five specimens were prepared following manufacturers’ with 10% fluoridric acid (Condac Porcelana, FGM), silanized (Pro-
instructions and were distributed into five groups (n = 7): sil, FGM), and the adhesive system (Ambar, FGM) was applied
■ CTR: 2-mm composite resin (control group) without light curing. For the resins, they were etched with 37%
■ HPM: Heat-pressed monolithic ceramics (IPS e.max) with phosphoric acid (Condac 37%, FGM) and a thin layer of adhesive
0.6-mm thickness was applied (Ambar, FGM). After that, the light-cured resin ce-
■ CCM: CAD/CAM monolithic ceramics (IPS e.max CAD) with ment (AllCem Veneer, FGM) was applied on the ceramic surface
0.6-mm thickness and the set was positioned over the resin base. The cement line
■ HPB: Heat-pressed monolithic ceramics (IPS e.max) with was standardized applying a 500 KgF weight positioned over
0.4-mm thickness + 0.2-mm fluorapatite glass-ceramic the ceramic surface for 5 seconds. Excesses were removed with
■ CCB: CAD/CAM monolithic ceramics (IPS e.max CAD) with a microbrush and the set was light cured for 40 seconds for each
0.4-mm thickness + 0.2-mm fluorapatite glass-ceramics. of the three surface points (120 seconds in total). All specimens
were stored in a 36.5°C incubator, for 24 hours.
For heat-pressed ceramics, a 0.4- or 0.6-mm thickness resin pat- A flexural strength test was performed with a three-point
tern (Duralay, Reliance Dental) was obtained through a metallic bending device adapted on an Universal Testing Machine with a
matrix (16 × 4 × 2 mm), with the aid of a 1.6- or 1.4-mm thick- 500 N loading cell (Instron model 3342, Instron) (Fig 1). The load
ness shim respectively. The resin pattern was connected to an was applied in the center between the two bases (with 12 mm
injection sprue with wax and the injection was made with aid between them) with the ceramic side under tensile stress, with
of a furnace (Programat EP 3000, Ivoclar Vivadent) using E-Max 0.5 mm/minute downward movement, perpendicular to the
Press HT A1 ceramic ingots. Ceramics were divested and composite resin surface, until specimen fracture. Flexural
cleaned with aluminum oxide blasting and ceramic excesses strength values were converted to MPa using the built-in soft-
were removed with specific abrasive disks. ware, having each specimen’s transversal section values as refer-
For the CAD/CAM groups, HT A1 E-Max CAD blocks were ence. The fractured samples were analyzed under a stereomicro-
cut with aid of a diamond disk and a cutting machine (ISOMET scope (Discovery V20 Zeiss) and representative samples were
Low Speed Saw, Buehler). The first cut was made separating gold sputtered and analyzed under a scanning electron micro-

QUINTESSENCE INTERNATIONAL | volume 51 • number 4 • April 2020 269


RESTORATIVE DENTISTRY

ics, and adequate marginal fit.7-9 Nevertheless, there are limited


data about mechanical properties comparing minimum thick-
ness ceramic restorations, especially regarding monolithic and
bilayered configurations and different manufacturing tech-
niques (heat pressed or CAD/CAM).
Flexural strength of heat-pressed and CAD/CAM lithium dis-
ilicate ceramics has been discussed, and the results have been
considered based on the manufacturing technique/process.
Blocks of lithium disilicate ceramics consist of a glass-ceramic
with the crystal phase composed by lithium disilicate crystals
(Li2Si2O5), corresponding to 60% of the total ceramic volume.
Blocks before milling present the material partially crystallized
(lithium metasilicate), with particle sizes ranging between 0.2 μm
and 1 μm, and a flexural strength of 130 MPa, to avoid damage
1 to the milling burs.11,12,15-17 During the crystallization process, at
840°C for 25 minutes, particle size increases under control, from
Fig 1 Three-point bending device adapted on the upper arm of the
Universal Testing Machine, with the specimen in position. 0.5 μm to 5 μm. During this process, prismatic glass-ceramics are
formed and dispersed over the glassy matrix. As the crystal spac-
ing becomes denser, the proportion of fine lithium disilicate
crystals within the glassy matrix increases 70% after crystalliza-
tion, and the flexural strength of the restoration increases to
scope (SEM Inspect S50, FEI). The obtained images were qualita- 360 MPa.11,12,15-17 The effects of the crystallization process can be
tively analyzed and described. Flexural strength data were sub- verified by approximately 0.2% to 0.3% shrinkage.18
mitted to the Shapiro-Wilk normality test, one-way analysis of It is important to note there is no reported shrinkage for
variance (ANOVA) (different treatments) and Tukey test. heat-pressed lithium disilicate, since the whole crystallization
process was performed industrially. In accordance with the pres-
ent results, the crystallization process does not seem to influ-
Results
ence flexural strength, resulting in similar strength values for
The control group, CCM, and HPM (respectively heat-pressed both CAD/CAM and heat-pressed techniques (CCM [monolithic
and CAD/CAM 0.6-mm ceramics cemented to a 2-mm compos- CAD/CAM]: 96.14 ± 20.60 Mpa versus HPM [monolithic heat-
ite resin base) showed the highest flexural strength (Table 1). pressed] 98.00 ± 25.62 MPa) (Table 1). Thus, the first null hypoth-
HPB and CCB (bilayer CAD and heat-pressed ceramics cemented esis was accepted. Such results are in agreement with the litera-
to a 2-mm composite resin base) showed similar results, but ture,12 despite controversial results.11 Different results can be
these were lower in comparison with the other groups (Table 1). explained by differences in method, for example assessing frac-
Fractographic analysis demonstrated that bilayer ceramics ture toughness based on a triangular ceramic prism, which can
showed fracture starting from the ceramic and progressing to lead to stress concentration and cracks11 that have different ori-
the composite base (Fig 2), whereas for monolithic ceramics, entations of crystals (random in CAD/CAM ceramics or paral-
the fracture pattern started from the composite and progressed lel-oriented and in higher density in heat-pressed ceramic).
up to the fracture of the ceramic (Fig 3). No debonding was There was also no observed difference between monolithic
observed either for the glass-ceramic or for the veneer ceramic. groups and the CTR group. Control group results are in accor-
dance with the literature using ISO 4049 (119.57 ±19.49 MPa
and 123.29 ± 21.92 MPa).19 In order to simulate clinical condi-
Discussion
tions, it is important to cement the specimens on tooth- or den-
Lithium disilicate ceramics might be the most frequently used tin-like substrate (ISO 6872 standard). The option for applying
material for minimum thickness veneers, and are associated the flexural force on the resin base surface was made because,
with good mechanical properties, chemical stability, biocom- clinically, the fracture origin is often located at the inner surface
patibility, reduction in bacterial plaque acumuli, good esthet- of the ceramic restorations.20

270 QUINTESSENCE INTERNATIONAL | volume 51 • number 4 • April 2020


Rizzante et al

Table 1 Results for flexural strength and elastic modulus

CCM: E-max CAD HPM: Heat pressed CCB: Bi-heat pressed HPB: Bi-CAD
Group CTR: control 2 mm 0.6 mm 0.6 mm 0.4 mm + 0.2 mm 0.4 mm + 0.2 mm
Flexural strength (MPa) 119.57 ± 19.49a 96.14 ± 20.60a 98.00 (25.62)a 54.85 ± 4.63b 50.86 ± 4.56b
a bc b bc
Elastic modulus (GPa) 6.48 ± 0.44 5.12 ± 0.19 5.31 (0.38) 4.83 ± 0.35 4.75 ± 0.32c
Different letters mean statistically significant difference between columns in the same row (inter-groups) (P ≤ .05).

Associating the demand of patients for esthetics with the Considering the fractographic analysis, it was interesting to
optical properties of lithium disilicate ceramics, a bilayer tech- observe the fracture pattern change with the different restora-
nique (lithium disilicate core + glass-ceramic veneer layer) was tive solutions (monolithic and bilayer). For bilayer ceramics, it
developed to achieve better esthetic results, since it becomes was observed that the facture started from the ceramic and pro-
possible to characterize each part of the restoration individually. gressed to the composite base, as the compression curl can be
There were no differences between flexural strength of bi- observed at the base of the composite (opposite side from the
layer lithium disilicate ceramics manufactured using CAD/CAM cementation line)(Fig 2). This was expected since the fracture
or heat-pressed techniques. Those results were expected since strength decreased for bilayered solutions, resulting in an
core ceramics from CAD/CAM and heat-pressed techniques “earlier” fracture.22 Interestingly, the fracture pattern for mono-
showed the same strength, and the layering process was the lithic ceramics was changed. It was possible to observe the
same for the different groups. Accordingly, the second null hy- compression curl located next to the cementation line, indicat-
pothesis was accepted. Nonetheless, the strength on bilayered ing that the fracture started from the composite base and pro-
groups decreased severely and the third null hypothesis was gressed to the ceramic (Fig 3). This might be explained by the
rejected. Bilayer technique reduced the flexural strength of the higher flexural strength of the monolithic ceramic, meaning that
set (resin base + resin cement + ceramic restoration) in about the tensile component of the force during the three-point bend-
50%, considering both CAD/CAM and heat-pressed techniques ing test was not able to fracture the ceramic. In addition, it can
(Table 1). These in vitro results can explain some clinical obser- be concluded that the compressive strength of the composite
vations, in which the literature reports more frequent failures/ was exceeded, leading to the beginning of the fracture. The
insuccess for bilayered ceramic restorations when compared integrity of the cementation line during all tests is noteworthy,
with the monolithic ones (1.53% versus 1.3% after 4 years),21 as as this shows the reliability of the adhesive cementation proto-
well as in vitro studies.9,22-24 Reduction of core ceramic thickness col.26 No debonding was observed at the interface between
for bilayered ceramics can reduce the strength (a reduction of composite and ceramic or core and veneer ceramic. Similar
0.8 mm to 0.4 mm may double the predicted fracture probabil- results regarding the interface between core and veneer
ity).23 Overall, a thicker core ceramic will result in more resistant ceramic have been reported.24
restorations.16,23 This is especially true because mechanical The veneering ceramic used in the present study is com-
properties of veneer ceramics are considerably lower,22 and posed of fluorapatite (E-max Ceram, Ivoclar Vivadent), and is
stresses can be generated between the ceramics interface. In- labeled to have a lower biaxial flexural strength and lower elas-
ner stress development can also happen due to manufacturing tic modulus when compared with the lithium disilicate blocks
process and physico-mechanical properties mismatch, contrib- and ingots. It is important to note that manufacturers test the
uting to early failures.24 In addition, veneered lithium disilicate material alone, without the interaction with core ceramics as
restorations are associated with higher teeth wear rates, due to assessed in the present study.
an increase in roughness during occlusal contact.25 Despite being a simplistic testing method, use of a flat spec-
When comparing the different elastic modulus, it can be imen reduced the possibility of manufacturing-induced errors.
noted that the set dentin/ceramic resulted in lower values, for Cementing ceramic veneers on dentin-like substrates (compos-
both monolithic and bilayer restorations, indicating that cemen- ite resin) allows close reproduction of clinical configurations
tation line/material may influence the elastic properties of the set, when compared with traditional isolated material bars.16 Further
mainly when ceramics with lower strength are used (bilayered). studies might focus on assessing the influence of the cementa-

QUINTESSENCE INTERNATIONAL | volume 51 • number 4 • April 2020 271


RESTORATIVE DENTISTRY

2 3

Fig 2 Broken half of a bilayer ceramic at 35× magnification. The Fig 3 Broken half of a monolithic ceramic at 35× magnification.
white arrows indicate the radial hackles surrounding the critical flaw Typical fracture surface for brittle materials. Radiating hackle lines
(origin of the fracture), as well as the direction of crack propagation can be observed surrounding the origin of the fracture and indicating
(dcp) (from the ceramic to the composite base). The compression curl the direction of the crack propagation (from the composite base
can be observed at the composite resin base, indicating the bending towards the ceramic). The black arrows indicate the compression curl
component immediately before the specimen’s total fracture. located at the cementation line.

tion material on the flexural strength of ceramic veneers, includ- of lithium disilicate ceramics. Nonetheless, flexural strength of
ing analysis of more complex geometries and stress distribution, bilayered ceramics can be severely reduced when compared
as well as their strength after artificial aging and/or fatigue tests. with monolithic solutions.
That being said, in the present authors’ opinion, the increased
failure risk and the possible increase in tooth wear does not jus-
Acknowledgments
tify the virtually better esthetic outcomes that a bilayered veneer
could generate when compared with monolithic veneers, espe- The authors thank Dr José Roberto Pereira Lauris, Professor at
cially considering the current painting and glazing techniques, Bauru School of Dentistry, University of São Paulo, for help with the
allowing the achievement of very natural results. Thus, mono- statistical analysis; and Dr Naiara Araújo de Oliveira, PhD student
lithic veneers are easier and faster to manufacture; at the same at the Department of Operative Dentistry, Endodontics and Dental
time they provide better mechanical properties and similar Materials at FOB-USP, for her help with the fractographic analysis.
esthetics when compared with bilayered veneers.

Declaration
Conclusion
The authors declare that they have no conflict of interest. The
Within the limitations of the present study, it can be concluded present study was supported by FAPESP (The São Paulo
that manufacturing techniques did not change flexural strength Research Foundation) (grant number 2014/13575-4).

References
1. Furuse AY, Santana LOC, Rizzante FaP, 2. Furuse AY, Glir DH, Rizzante FaP, 3. Rizzante FAP, Locatelli PM, Porto TS,
et al. Delayed light activation improves color Prochnow R, Borges AFS, Gonzaga CC. Degree Borges AFS, Mondelli RFL, Ishikiriama SK.
stability of dual-cured resin cements. of conversion of a flowable composite Physico-mechanical properties of resin
J Prosthodont 2018;27:449–455. light-activated through ceramics of different cement light cured through different
shades and thicknesses. Braz J Oral Sci 2015; ceramic spacers. J Mech Behav Biomed
14:230–233. Mater 2018; 85:170–174.

272 QUINTESSENCE INTERNATIONAL | volume 51 • number 4 • April 2020


Rizzante et al

4. Karagozoglu I, Toksavul S, Toman M. 12. Fabian Fonzar R, Carrabba M, Sedda M, 20. Thompson JY, Anusavice KJ, Naman A,
3D quantification of clinical marginal and Ferrari M, Goracci C, Vichi A. Flexural resis- Morris HF. Fracture surface characterization
internal gap of porcelain laminate veneers tance of heat-pressed and CAD-CAM lithium of clinically failed all-ceramic crowns. J Dent
with minimal and without tooth preparation disilicate with different translucencies. Dent Res 1994;73:1824–1832.
and 2-year clinical evaluation. Quintessence Mater 2017;33:63–70.
Int 2016;47:461–471. 21. Sulaiman TA, Delgado AJ, Donovan TE.
13. Rizzante F, Ishikiriama S, Mendonça G. Survival rate of lithium disilicate restorations
5. Gresnigt MMM, Ozcan M, Carvalho M, A brief discussion about the use of technolo- at 4 years: a retrospective study. J Prosthet
et al. Effect of luting agent on the load to gies in life sciences: review and future Dent 2015;114:364–366.
failure and accelerated-fatigue resistance of
perspectives. J Dental Sci 2017;2:000127. 22. Lin WS, Ercoli C, Feng C, Morton D. The
lithium disilicate laminate veneers. Dent
Mater 2017;33:1392–1401. 14. Seydler B, Rues S, Muller D, Schmitter effect of core material, veneering porcelain,
6. Beier US, Kapferer I, Burtscher D, M. In vitro fracture load of monolithic lithium and fabrication technique on the biaxial flex-
Dumfahrt H. Clinical performance of porce- disilicate ceramic molar crowns with differ- ural strength and weibull analysis of selected
lain laminate veneers for up to 20 years. Int ent wall thicknesses. Clin Oral Investig dental ceramics. J Prosthodont 2012;21:
J Prosthodont 2012;25:79–85. 2014;18:1165–1171. 353–362.
7. Silva NR, Thompson VP, Valverde GB, 15. Jian Y, He ZH, Dao L, Swain MV, Zhang 23. Nawafleh N, Hatamleh MM, Ochsner A,
et al. Comparative reliability analyses of XP, Zhao K. Three-dimensional characteriza- Mack F. The impact of core/veneer thickness
zirconium oxide and lithium disilicate restor- tion and distribution of fabrication defects in ratio and cyclic loading on fracture resis-
ations in vitro and in vivo. J Am Dent Assoc bilayered lithium disilicate glass-ceramic tance of lithium disilicate crown. J Prostho-
2011;142:4–9. molar crowns. Dent Mater 2017;33:178–185. dont 2018;27:75–82.
8. Cortellini D, Canale A. Bonding lithium 16. Zhang Y, Lee JJ, Srikanth R, Lawn BR. 24. Wang XD, Jian YT, Guess PC, Swain MV,
disilicate ceramic to feather-edge tooth Edge chipping and flexural resistance of Zhang XP, Zhao K. Effect of core ceramic
preparations: a minimally invasive treatment monolithic ceramics. Dent Mater 2013;29: grinding on fracture behaviour of bilayered
concept. J Adhes Dent 2012;14:7–10. 1201–1208. lithium disilicate glass-ceramic under two
9. Zhao K, Wei YR, Pan Y, Zhang XP, Swain 17. Kim JH, Oh S, Uhm SH. Effect of the loading schemes. J Dent 2014;42:1436–1445.
MV, Guess PC. Influence of veneer and cyclic
crystallization process on the marginal and 25. Figueiredo-Pina CG, Patas N, Canhoto J,
loading on failure behavior of lithium disili-
internal gaps of lithium disilicate CAD/CAM et al. Tribological behaviour of unveneered
cate glass-ceramic molar crowns. Dent Mater
2014;30:164–171. crowns. Biomed Res Int 2016;2016:8635483. and veneered lithium disilicate dental mater-
10. Hamza TA, Sherif RM. Fracture resis- 18. Wiedhahn K. From blue to white: new ial. J Mech Behav Biomed Mater
tance of monolithic glass-ceramics versus high-strength material for Cerec: IPS e.max 2016;53:226–238.
bilayered zirconia-based restorations. CAD LT. Int J Comput Dent 2007;10:79–91. 26. Romanini-Junior JC, Kumagai RY,
J Prosthodont 2019;28:259–264. 19. Rosa RS, Balbinot CE, Blando E, et al. Ortega LF, et al. Adhesive/silane application
11. Alkadi L, Ruse ND. Fracture toughness Evaluation of mechanical properties on three effects on bond strength durability to a lith-
of two lithium disilicate dental glass ce- nanofilled composites. Stomatologija ium disilicate ceramic. J Esthet Restor Dent
ramics. J Prosthet Dent 2016;116:591–596. 2012;14:126–130. 2018;30:346–351.

Fabio A. P. Rizzante Suellen S. Senna Alumni, Bauru School of Dentistry, University


of São Paulo, Bauru, São Paulo, Brazil
Carla M. Ramos-Tonello Assistant Professor,r Department of Re-
storative Dentistry – FMU Education Group, São Paulo, SP, Brazil
Rafael F. L. Mondelli Department Chair,r Department of Opera-
tive Dentistry, Endodontics and Dental Materials, Bauru School of
Dentistry, University of São Paulo, Bauru, SP, Brazil
Sérgio K. Ishikiriama Associate Professor,r Department of Oper-
ative Dentistry, Endodontics and Dental Materials, Bauru School of
Dentistry, University of São Paulo, Bauru, SP, Brazil
Fabio A. P. Rizzante Assistant Professor,r Department of Compre-
hensive Care, School of Dental Medicine - Case Western Reserve Ana Flávia S. Borges Associate Professor,r Department of Oper-
University, Cleveland, OH, USA ative Dentistry, Endodontics and Dental Materials, Bauru School of
Dentistry, University of São Paulo, Bauru, SP, Brazil
Idiane B. L. Soares-Rusu PhD candidate, Department of Opera- Zvi Gutmacher Department Chair,r Department of Maxillofacial
tive Dentistry, Endodontics and Dental Materials, Bauru School of Rehabilitation, School of Graduate Dentistry, Rambam Healthcare
Dentistry, University of São Paulo, Bauru, SP, Brazil Campus, Haifa, Israel

Correspondence: Dr Fabio Antonio Piola Rizzante, Department of Comprehensive Care, Case Western Reserve University, School of
Dental Medicine - 9601 Chester Avenue, Room 340, Cleveland, OH 44106, USA. Email: fap17@case.edu

QUINTESSENCE INTERNATIONAL | volume 51 • number 4 • April 2020 273

You might also like