UTI GUIDE:

Acute Uncomplicated UTI:

Preferred PARENTERAL Regimen:

Recurrent Catheter-Related UTI or with co-morbidities:

▪ Use cefotaxime instead of ceftriaxone in jaundiced patients.

▪ If Pseudomonas is suspected, use ceftazidime instead of cefotaxime.

▪ Cephalosporins are not recommended if Enterococcus is suspected.

▪ Preferred Regimen for Prophylaxis

▪ Nitrofurantoin 1-2mg/kg/d (up to 100 mg/d) PO in 1-2 div doses

Hospital-Acquired UTI:

EAU GUIDELINES: TREATMENT FOR ACUTE CYSTITIS

ANTIBIOTICS DAILY DOSE DURATION COMMENTS

OF THERAPY
First choice
Fosfomycin trometamol 3g Single Dose 1 day
Nitrofurantoin macrocrystal 100 mg BID 5 days Avoid G6PD deficiency
Pivmecillinam 400mg TID 3 days
Alternatives
Ciprofloxacin 250 mg BID 3 days Not during pregnancy
Levofloxacin 250 mg QD 3 days Not during pregnancy
Ofloxacin 200 mg BID 3 days Not during pregnancy
Cephalosporins (e.g. cefadroxil) 500 mg BID 3 days
If local resistance pattern is known (E. coli resistance < 20%)
Trimetophrim 200 mg BID 5 days Not in the first trimenon of
pregnancy
Trimethoprim + Sulfamethoxazole 160/800 mg BID 3 days SMX not in the last trimenon of
pregnancy
Three-day regimen for acute uncomplicated cystitis in women

EAU GUIDELINE FOR MILD AND MODERATE

TMP/SMX 160/800 mg BID

Nitrofurantoin 100 mg QID

Norfloxacin 200 mg BID

Ciprofloxacin 250 mg BID

Perfloxacin 400 mg BID

Ofloxacin 200 mg BID

Co-amoxiclav 375 mg TID

EAU GUIDELINE FOR SEVERE: