National eieeithensive NCCN Guidelines Version 3.2020 cet Gunes index wy cence, Esophageal and Esophagogastric Junction Cancers Discussion ‘American Joint Committee on Cancer (AJCC) ‘TNM Staging Classification for Carcinoma of the Esophagus and Esophagogastric Junction (8th ed., 2017) ‘Squamous Cell Carcinoma and Adenocareinoma ‘Table 1. Definitions for T, N, M non toms woven casas Ts HORSES Re taemanmcnorang a cots confines 10M i ctotogie Grade ‘suomucosa G1 Well differentiated Teg Rmzimosrne mea poriermacimovcte G2 ey ert 2 ‘Tumor invades the muscularis propria G3. Poorly diferentiated, undiferentiated 3 ‘Tumor invades adventitia ‘Squamous Cell Carcinoma Be ae mamma ‘Tab verona Ge ce, ‘structures, such as the aorta, Middle Loner border of azyg0e ‘vein to lower border of inferior 4 Metastasis in one or two regional lymph nodes N2_ Metastasis in three to sx regional lymph nodes 3 Metastasis in seven or more regional Iymph nodes Continued Used.th permission of the American Colege of Suigeons, Chicago lines. The original soulce for this information & the AJCC Cancer Staging Manual, Eighth Eton (2017) pubished by Springer Intemational Publishing st