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Table S1.

Changes from baseline of FGM-derived glucose metrics during lockdown in the


subgroup of patients who did not undergo consultation with a diabetologist.

Baseline (T0) Lockdown (T1) Difference p


(T1-T0)
MSG (mg/dl) 157.6 ± 24.8 159.7 ± 27.16 2.13 ± 14.7 0.38
GMI (%) 7.1 ± 0.6 7.1 ± 0.6 0.05 ± 0.3 0.41
CV (%) 37.3 ± 7.0 34.2 ± 5.6 -3.1 ± 5.4 0.0014
TIR (%) 61.3 ± 14.7 61.4 ± 17.6 0.05 ± 10.2 0.9
TAR (%) 32.8 ± 15.4 34.5 ± 18.2 1.7 ± 10.0 0.31
TBR (%) 5.8 ± 5.3 4.1 ± 2.9 -1.76 ± 4.5 0.02
Hypoglycemic events 10.0 [5.0– 16.50] 9.0 [5.0 – 13.0] -2.0 [-4 – 0] 0.0131
(N)
Scans/day (N) 11.0 [9.0– 15.0] 13.0 [9.0– 17.0] 1.0 [-1.0 – 3] 0.17

Normally distributed data are expressed as mean ± standard deviation and non-normally distributed
data are expressed as median [interquartile range].
Differences between paired groups of normally distributed data have been assessed with Student's t-
test, whereas differences between paired groups of non-normally distributed data have been
assessed with the Mann-Whitney test.
MSG, mean sensor glucose; GMI, glucose management indicator; CV, coefficient of variation; TIR,
time in range (70-180 mg/dl); TAR, time above target glucose range; TBR, time below target
glucose range.
Statistically significant p-values are in bold.
Table S2. Difference in changes from baseline of FGM-derived glucose metrics during
lockdown between patients on MDI (Multiple Daily Injections) or on CSII (Continuous
Subcutaneous Insulin Infusion).

CSII (N=9) MDI (N=39)


Difference Difference Difference p
(T1-T0) (T1-T0) (MDI-CSII)
MSG (mg/dl) 7.3 ± 19.7 1.13 ± 13.8 -6.2 ± 5.5 0.27
GMI (%) 0.2 ± 0.5 0.03 ± 0.3 -0.1 ± 0.1 0.32
CV (%) -3.9 ± 5.3 -2.9 ± 5.2 0.9 ± 1.9 0.61
TIR (%) 1.3 ± 7.3 -0.3 ± 10.2 -1.6 ± 3.6 0.65
TAR (%) 2.8 ± 9.5 1.6 ± 9.9 -1.2 ± 3.6 0.74
TBR (%) -1.0 [-9.0 – 0.5] -1.0 [-3.0 – 1.0] 0.0 [-1.0 – 5.0] 0.25
Hypoglycemic -5.0 [-11.5 – 1.5] -2.0 [-7.0 – 1.0] 3.0 [-3.0 – 9.0] 0.24
events (N)
Scans/day (N) 1.0 [-1.5 – 2.0] 1.0 [-2.0 – 3.0] 0.0 [-2.0 – 3.0] 0.64

Normally distributed data are expressed as mean ± standard deviation and non-normally distributed
data are expressed as median [interquartile range].
Differences between unpaired groups of normally distributed data have been assessed with
Student's t-test, whereas differences between unpaired groups of non-normally distributed data have
been assessed with the Mann-Whitney test. 
MSG, mean sensor glucose; GMI, glucose management indicator; CV, coefficient of variation; TIR,
time in range (70-180 mg/dl); TAR, time above target glucose range; TBR, time below target
glucose range.

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