Stimulate ADH release

Drugs : barbiturates, clofibrate, nicotine and morphine.

(

ADH difficncey (DI)

drugs (demeclocycline & lithium).

ADH Excess SIADH

drugs like chlorpropamide, cyclophosphamide & carbamazepine.

synthetic oxytocin (Syntocinon) is used clinically to initiate labor.

Prolactin stimulator
• Dopamine antagonists (e.g. phenothiazines)

Factors that increase TBG

Certain drugs (clofibrate, tranquilizers …)

Drugs that inhibit binding of TBG to thyroid hormones (decrease total hormone) include: •
Aspirin • Phenytoin

Anti-inflammatory effect: • Treating patients with high doses of prednisolone or

hydrocortisone)

Insulin control = stimulation

• Drugs :sulfonylureas, theophylline, β adrenergic agonists

Glucagon inhibition
Drugs (phenytoin, α adrenergic agonists ).
Stimulation
Drugs (β adrenergic agonists, theophilline )