Professional Documents
Culture Documents
n Measles
n German measles
n Chicken Pox
n Herpes Zoster
n influenza
n COVID-19
Measles description
n is one of the most contagious infectious
diseases, with at least a 90% secondary
infection rate in susceptible domestic
contacts.
n Despite being considered primarily a
childhood illness, measles can affect
people of all ages.
pathophysio
n Infection is transmitted via respiratory
droplets, which can remain active and
contagious, either airborne or on surfaces,
for up to 2 hours.
n Initial infection and viral replication occur
locally in tracheal and bronchial epithelial
cells.
n After 2-4 days, measles virus infects local
lymphatic tissues, perhaps carried by
pulmonary macrophages.
n Following the amplification of measles
virus in regional lymph nodes, a
predominantly cell-associated viremia
disseminates the virus to various organs
prior to the appearance of a rash.
Measles
n Synonyms: Rubeola; First disease, Little
red disease
n Causative agent: Paramyxovirus
n Incubation: 7-14 days (average 10-14
days)
n MOT: droplet -spread by coughing and
sneezing via close personal contact or
direct contact with secretions.
n * Period of communicability: 4days before
to 5 days after the appearance of rashes
Signs and symptoms
1. Prodromal -Pre-eruptive:
>fever 3-4days, malaise, anorexia
> 3 Cs:
Cough, coryza, conjunctivitis
Enanthem phase> Pathognomonic
sign- Koplik spots – fine red spots with
bluish-white spot at center found in
the inner cheek
Koplik spot
2. Exanthem- Eruptive:
2. Eruptive
> rashes (exanthem)– maculopapular
(smaller than measles) ; cephalocaudal; lasts
for 2-3 days & leave no desquamation nor
pigmentation
> enlargement of lymph nodes: sub-occipital,
post. Auricular, post. Cervical
Forscheimer spots
3. Post-eruptive:
> rash disappears
> enlargement of lymph nodes begin to
disappear
n Congenital anomalies
– Microcephaly
– Heart defect
– Cataract
– Deaf-mutism
n Theclient should avoid pregnancy for 1 to
3 months after immunization with rubella
vaccine
Chicken pox
Prevention
Annual vaccination for high risk people or
for individuals who wish to reduce
chances of getting flu
Avian Influenza
Synonym: Bird flu, AI
Causative agent: Influenza A H5N1 virus
MOT: Direct contact with droppings of infected
bird
Signs and symptoms: Fever, body weakness or
muscle pain, cough, sore throat, sore eyes, DOB
Management: Same as influenza
Prevention: No vaccine available yet, avoid
migratory birds, Thorough cooking of poultry
meat
How long will it stay on the
surface?
n Feces and urine in room temp-2 days
n Paper and plastered wall- 36 hrs
n Stainless=72 hrs
n Glass slides-96 hrs
n Loses its infectivity when expose to
disinfectants.
n Heat at 56 c rapidly to kill the virus
COVID-19
n Coronavirus disease (COVID-19) is an
infectious disease caused by a newly
discovered coronavirus.
n spreads primarily through droplets of
saliva or discharge from the nose when an
infected person coughs or sneezes
n highly transmittable and pathogenic viral
infection caused by severe acute
respiratory syndrome coronavirus 2 (SARS
-CoV-2), which emerged in Wuhan, China
and spread around the world.
n Genomic analysis revealed that SARS-CoV-
2 is phylogenetically related to severe
acute respiratory syndrome-like (SARS-
like) bat viruses, therefore bats could be
the possible primary reservoir.
n mildto moderate respiratory illness and
recover without requiring special
treatment.
n Older people, and those with underlying
medical problems like cardiovascular
disease, diabetes, chronic respiratory
disease, and cancer are more likely to
develop serious illness.
n On average it takes 5–6 days from when
someone is infected with the virus for
symptoms to show, however it can take
up to 14 days.
n The incubation period for COVID-19 is
thought to extend to 14 days, with a
median time of 4-5 days from exposure to
symptoms onset.
Signs and symptoms
n Most common symptoms:
n Fever, dry cough, tiredness.