Multiple sclerosis is a disorder that causes demyelination/damaged of myelin
sheaths and underlying nerve fibers in the eyes, brain, and spinal cord. In MS, an abnormal immune system response produces inflammation that results in malfunctioning of the nerves causing a central neuropathic pain. A person with MS may feel tingling, numbness, pain, burning and itching in the arms, legs, trunk, or face and loss of strength in a leg or hand. According to National Multiple Sclerosis Society, a person with MS can experience two types of neuropathic pain, an Acute Neuropathic pain and Chronic Neuropathic pain. An acute neuropathic pain is a sudden/slow onset of symptoms and has short duration, whereas chronic neuropathic pain is prolonged, usually recurring/persisting over 6 months or longer.
DIABETES
Poor control of blood sugar levels in diabetes causes several forms of
polyneuropathy or referred as Diabetic Neuropathy. Polyneuropathy is the malfunction of many peripheral nerves throughout the body. Diabetic neuropathy commonly causes painful tingling or burning sensations in hands and feet. Pain is often worse at night and may be aggravated by touch or by a change in temperature. Polyneuropathy/Diabetic Neuropathy may be acute (beginning suddenly) or chronic (developing gradually, often over months or years).