Scribd Logo
Upload

Welcome to Scribd!

  • M Tech

    Uploaded by

    Sindhu Kamat
    219 views6 pages
    .....

    Original Title

    M.Tech

    Copyright

    © © All Rights Reserved

    Available Formats

    PDF or read online from Scribd

    Did you find this document useful?

    Is this content inappropriate?

    Report this Document
    .....

    Copyright:

    © All Rights Reserved
    Download as PDF or read online from Scribd
    Flag for inappropriate content
    219 views6 pages

    M Tech

    Uploaded by

    Sindhu Kamat
    .....

    Copyright:

    © All Rights Reserved
    Download as PDF or read online from Scribd
    Flag for inappropriate content
    of 6
    Tao Tamme] TAR ‘S3AL9313 N3dO oe Taman URES HTN Be tbea ease | 08 0 Tam PRD | SHO austen eA HES [01058 Saami RL ata wo peng | OOS Taman rae} 60 08 nna aulesoa | 08 Om Td Taio ara oun] Ds Tian | TOO Se ‘S3AIL9373 WWH90Ud zoo [a sfopofo pM | OO eR ee rE slats Pate Tepe fa mR oe en rp pepo Tawar manmeveine] seson [eps po] o Tosa epepote HTP weew ee PLO PELE aes w en eo rpepe pe oan [sao Ty [OTP Le GRU CIRO ORR | STS epee van seo Tr LO] Te Tang oneRdoapINOY | TSO] rpepote ee Taras snoring ATEN | 151508 rfolile sxmeayowe besa oceene| veeson | 2 |e | 0 von pe 99 TT sn v fol re] vormmasnmssimareveronssionie| iszsom [> [os [©] wy amtamatSRstnogni ROT 5.5 yn aaa Sane mem popata a San oes om eee PE (sprenuo uotssiupe 6102 0 ageayddy) aumonng wesBo1g ADOTONHO3L018 TWIHLSNONI “YoaL'W. |edquew J1W ‘ASOTONHOaLOIM 40 INaWeVaIO 39 Basen MATS158 MATHEMATICAL AND NUMERICAL TECHNIQUES INCHEMICAL AND BIOLOGICAL ENGINEERING [3 1 0.4] Soltion of system of near equations by direct an eration method, Eigen valves and Eigen vectors of Matices by iterate mathod, Raykigh's Power method, Numerical Integration by composite inlegraton methods, Regression-Linea, Polynoml, muliole linear, Non-linear regression, Orthogonal polynomials and functions. Algebraic and transcendental equatons-terave methods. Numerical soliton of iferenial equations-Inal value problems. and boundary value problems- Single and mutistep methods. Multivariate nor-lingar ‘optimization without constants Retorences: 1. MK dan, S.RK.lyengar and RX. Jain, Numerical methods for sciente and engineering computation, New age international (P) Limited, Publisers, SanthoshK.Gupta, Numerical methods fr Engineer, Wi Eastern Lid, New Deh HUM 5151 RESEARCH METHODOLOGIES AND TECHNICAL ‘COMMUNICATION [1.032] Mecharies of Research Methodology; Basic concepts: Types. of research, Significance of research, Research framework, Case study method, Experimental method, Sources of data, Data colton using ‘questionnaire, Interviewing, and experimentation Research formulation: Components, selection and formulation of @ research problem, Objectives of formulation, and Criteria of a good research problem: Research hypothesis: Criterion for hypothesis constuction, Nature of hypothesis, Need for raving a working hypothesis, Charactestis and Types of hypothesis, Procedure for hypotesis tating; Sampling Methods: Induction to various. sampling methods and. ther applications; Data Analysis: Sources of data, Colecton of dat, Measurement and scaling technique, and Diferet techniques of Data analysis; Thesis Wiking and Journal Publication: Writing thes, Writing journal and conerence papers, IEEE and Harvard styles of reterencng, Etfectve Presentation, Copyrights, andavoidng plies. References: Dr Ranjit Kumar, Research Methodology: A Step-by-Step Gude for Beginner, SAGE, 2005, 2, Geattey R. Marczyk, David DeMatteo & Davi Festinger, Essential of Research Design and Methodology, John Wily & Sons, 2008 BIO S151 ADVANCED BIOPROCESS ENGINEERING [3 10 4] Structure properties and classitcation of carbohydrates, iis, proteins & nucleic. acids; Prokaryotes & Eukaryotes; Bacterial Taxonomy, Microscopy; Isolation, Preservation and improvement of Industral Micro-Organisms; Medium requirement) Swizaon - batch end continuous, iter sterilization. Design of sterilization auipment Clesiication of Enzymes; Mechanism of Enzyme Acton Determination of elementary stp rte kinetics, patterns of substrate ‘concentration dependence, modulation and regulation of enzyme activity, Phases of call orowh in batch cutures - transient growth kinetics, Simple unstructured kinetic models for microbial growth, ‘Growth of flamentous organisms; Condtions affecting grown Kneis, subsvate & product Inhibition on cell growth & product formation siructured kieto models, segregated kinele models of growth Material Balance calculations, Stoichiometry of microbial growth & Product formation, Eneray ~ Balance Calculations with and Without Reactions; A brief outine af pracesses forthe production of same 40 commerialy important Organic acid, amine acids ad alconols, study of production processes for various classes of low molecular weight sacondary metabolites: Antibiotics, qunoves, aromas, Vitamins ana Stero, References: 4. Michael Shuler and Fret Kargi, Bioprocess Engineering: Basic Concepts (2), Prentice Hal, Englewood Cis, Ni, 2002 2. Pauline M Doran, ioprocess engineering principles (Te), Academic Press, 1995, B10 5152 ADVANCED BIOSEPARATION PROCESSES [31 0 4] Role of Downsteam Processing in Bitechnology; Economics ana downstream processing, Cost cuting, Gel disruption; flocculation, Sedimentation, centifugaion and fiation; Precipitation methods; Bacton: Batch, staged -eross current, co curet, counter cute, Diferenta fractional, Aqueous two-phase, Reverse miele extraction, supetrtical fhid edraction, Design & configuration of membrane separation equipment R.0., dllyss,elcro dalysis, IF; Adsorption isotherms, indutial adsorbents, adsorption equipments for batch ana continuous operations, adsorption in xed beds; Chromatography: Gel ‘iain, reversed-phase, hydrophobic interaction, ion-exchange expanded bed adsorption, bio afinity and IMAC, supetriial fit Preparation of commercial enzymes: proyht RNA synthetase inreclulr foreign proteins trom recombinant Ecol and extracellular proteaserecovery biosurfactant 4, Beltr PA, CusslerE and Wo Shan Hu, Bioseparation— Downstream Processing for Biotechnology, Wily Ilerscience, 1988. 2. Asenjo and Juan A. Aseno, Separation Processes in Biotectnalogy, (ORC Press, 1990, BIO 5153 MOLECULAR BIOLOGY & «-DNA TECHNOLOGY [3 1 04] Forms of ONA & RNA, Organization of ONA; DNA Replication in Prokarytes & Eukaryotes, Telometic Replication; Replication of Viral DNA; Transcription in Prokaryotes & Eukaryot, Post‘ransciptonal Modietions, Genetic Code, Wobble Hypothesis, Translation in Prokaryoles & Eukaryotes,Postsranslational Modifications, Operon; DDNA Repa, Mutations and Mutagenesis; Basic of (DNA Technology; Enaymes in Genet Engineering: Nucleic Acid Hybiizaon, Probes & DNA Libraries: Restction Mapoing, Adaptors & Linkers, PCR, RFL?, APD, DNA Sequencing; SNPS, YNTRs; Therapeutic proteins from Transgenic plants & animals," Gene Therapy; Recombinant DNA Vaccines; Resistance to Herbicides, vius, insect and pass, Stress tolerance; DNA fingerprinting, Directed’ mutagenesis, Antsense Toctnalogy Relerence: 1. Davi releldr Molecular Blology (2), Jones and Barat, Pualshers Ine, 1987. 2, BanjaminLowin, Genes Vl, Prentice Hall, 2004, ‘IO 5154 TRANSPORT PHENOMENA IN BIOPROCESS ENGINEERING [9 1 0.4) Iroducton to Momentum, heat ané mass transfer, Uniti equation of ‘momentum heat and mass transfer, Shell Momentum balances and valet estibutions in laminar flow ow ofa faling fm, circular tube flow though an annulus, flow of two adjacent immiscible Huds, The ‘equations of change for isothermal systems, equalion of mation and ‘dimensional analysis. Heat conduction and convection in diferent systems using sell energy balance to find out temperature distbuton. Ditfusty andthe Mechanisms of Mass Transport Difusion through ‘stagnant gas fim, hamageneaus and heterogeneous chemical reaction, 925 absorption and porous catalyst. Velocity distibutions wit moe than ‘one independent variable, The equatons of change for non-fsotheral systems, Temperature distributions with more than one independent variable, Equaons of change for muticomponent systems, Rotoronces: 1 Arthur T. Johnson, Biological Process Engineering: An Analogical ‘Approach to Flue Flow, Heat ranser, and Mass Transfer Applied to Biological ystems, John Wiky and Sons, 1988. Blanch H.W and Douglas S.C, Biochemical Engineering, CRC Press, 1997, BIO 5161 BIOPROCESS ENGINEERING LAB [0.06 2} Pure cule techniques SOS ~ PAGE of proteins, Microbial growth kines, Efect of substrate concentration on kinetics of invertase ‘erayme,Enzyme immobiizaton protocol by entrapment method In alginate gel Deactvaton kinetics of invertase enzyme, Stutes on mass transfer effects onthe perormance of erzyme enrapped in alginate ‘gelatch recycle immobilized packed bed bioceacto;Continuous flow immobiized enzyme packed bed bio reactocFudized bed bioreactor (FBR) for enzyme kineies,Satch heat striization and thermal death Kinetics BIO 5162. TISSUE CULTURE AND SEPARATIONS LAB [0.031], Characterization of plant cell suspension cutures-ell growth, Cel ‘count, heterogeneity and viabilty, Isolation, icetiicaton and ‘qanticaton of secondary metabolite berberine from in vito cukures and field grown plats, soation of RNA ftom Plant, Isolation of RNA ‘tom Pans, Organel isolation and marker eneyme assay, Determining cel viabily, Tawing of frozen cell lin, Sub-cuftung of cel, Utre filation, Size Excision Chromatograpty, Paritoningof Protein Basen BIO 5251 BIOPROCESS MODELING, ANALYSIS & SIMULATION [3 1 04) Perspective on modeling of physical, chemical &bilogial phenomena, uses and Imiatons_of mathematical models; Examples involving algebraic, ordinary diferent, dference, partial diferent, integral & intgto-diferental equations; Probabity theory, stochastic models parameter estimation model forms for parameter estimation. Parameter estimation using moments, design of experiments; Accuracy of parameter estimates. Design of experiments for model discrimination; Non tinear systems; Plane analysis in classical bioreactor models; Nonlinear dynamies; Chaotic behavior, cob wed diagrams, stably of ‘xed point soluions. Biurcaions behavior, Chaos; Lorenz equations; Populaton balance modeling, Budding of yeast popuation Modeling ot els wih dynamic morphology ~ Modeling fo biological popuations with correlation between ite spans of siblings. Modeling of Industrial stetiizaton processes Reterences: 1. Wayne Baquette 8, Process dynamics modeling and analysis and simulation, rence allie, 2004 JH. Seinfeld and Leon Lapidus., Mathematical Methods in ‘Chamical Engg, (Vol. 3), Process. Modeling, Estiatons and Identtcation, Pemice Hall, 1974 2, 4“ BIO 5254 BIOREACTOR DESIGN AND ANALYSIS [3 1 0 4] Nass transfer ttc nheterogeneous reaction system; Chemostat with call cultures; CSTR with immobieed enzymes, operon of CSTR in constant feed rate poley; Chemastals In saris; Plug flow reactor, Performance equation wih MLM knees, substrate & product inhibition Kintics, PER for immobilzed enzymes, Simulation for conversion; Fed-batoh reactor, Stabity analysis, Eigenvalues; Bioreactor conto Coniraaitty matrix; Design of P-contoler for Turbidostat & Nutstal operation; Biological waste water treatment with Feed forward conzal, Various industrial Bioreactor; aeration and oxygen mass transfer in bioreactor system, RTD, £, C F-curves, Micro & Macro fuid Retorencos: 4. Blanch H.W and Douglas S. Clark, Biochemical Engineering, CRC Press, 1997, 2. Michael L Shuler and Five Karl, Boprocess Engineering: Basic Concepts, Pranica-Hal of IndiaPviLtd, 2008, BIO 5265 BIOMOLECULAR DATA ANALYTICS LAB [0.0 31) Information reteval rom databases, Sequence algnment Pairwise ana Multiple sequences, Basics of PERL programming, Prmer Design, Protein secondary structure. prediction, Structure visuazaon & analysis, Protein modeing, analyss, and validation, Protein-igana locking, Protein-protin docking, 0-prining of biomolecules 810 5286 MODELING, SIMULATION AND CONTROL LAB (0 031], Representation of transfer functions and inpu-outpt- models using Nalad commands, Response pls, stably analysis and design of proportional coil fr bioeactoPerfrmance analysts of fed atch and. chemostat reactors ~soluion for set of lfeential equations, Performance analysis of bioreactor using Matla-use of phase plane analysis, Inroducton ta Simulink and building a dynamic model for fermentation process wih Simulink, Design a chemostat using grapher (GUI interface), Flow contol trainer, Temperature measurement and calbration of thermometors & first order systems, Non interacting & interacting system, Fistorder& sacond odarsystam ESiSa ee BIO 6098 PROJECT WORK [0 0.025} Studonts are oquied to undertake Innovate and research arientad projects, which not only retect their knowledge gained inthe previous ‘wo semesters but also reflects adonal knowledge gained trom thei own ator. The project work can be cared out in the instuton! industry research laboratory or any otter competent instutons. The uration of project work shouldbe aminimum of 36 weeks. There wl be a mid-erm evaluation of the projct work done after about 18 weeks. An interim projectreport is to be submited tothe dapariment dung the mid-term evaluation. Each student has to subrat tothe department a projectreport in prescribes format after completing the work. The fal ‘evaluation and viva-voic wil be after submission of the report, Each student has to make a presentation onthe work carted out, before te ‘departmental committee for project evaluation. The mid-erm & end semester evaluation wil be done by the departmental commits inetuding he quces. PROGRAM ELECTIVES ‘IO S001 ANIMAL AND PLANT BIOTECHNOLOGY [40 04) Plant Genome; Taipoleney, Regeneration of ples; Auolrphic and heterotrophic grow, Plant growth regulators. and elctors, Cal suspension culture development Production of secondary metabolites, Hairy root cutures & ther cutivation; Direct and indict methods; Chernical: Biological Patents & PBAs; Animal cellmtabolism& growth characteristics, Rogulaton & ruflonal requirements; Substrate and product transport through mammalian col growth Kntics and shear force. Micro & Macro carrer atached growth, Cal cute in continuous, perfusion & hollow-fber reactor; Hybicloma technology, Lvestock improvement, Gene transfer methods, Transgenic animals Xenoiransplaniation, ce preservation; PRissues References: ‘Dxan R.A and Gonzales, Plant Cll Culture: A Practical Approach, IRLPress, 1995. 2. Lindsey. K and MG. Jones, Plant Biotechnology in Agriculture, Prontice Hal, Now Jersey, 1990. B10 5002 BIOMOLECULAR DATA ANALYTICS [4 0.04] DNA, RNA, Flow of genetic information, Genetic code, Transcription, Translation, HGP & Digital code of Le; Sequence Databases, Nuceotse & protein databases. Information revival; PDB; MMOB at NCBI, Stucture fle formals; evoluionary basis ‘of sequence. alignment, Modular Natu ot protsins, Optional Nignment Methods, BLAST, FASTA, Low-Complexty Reojons, Repettve Elements. Parwise & Multiple ‘sequence algnment, Proteins - Secondary structures, Mais, Damans, Tertary & quaternary structues- Ramachandran pot; RNA structure; Rivosome; RNA Secondary Structure Prediction, Set & Graph theory, ‘Strings & Algorthins, Chemical graphs; Hierarchical Levels in Biodiversity, Genetic diversity; Biodiversity issues; Methods for species identicaton & classtication, Biodiversity Databases; Tee fie project, Elements of phylogenetic Models, Phylogenetic Data Anadis, Substluton Model Bullng, Tee Bulg & Evaluation, Buldingthe Data Model (Aignmani), Determining the Substitution Mode, Tee ~Buling Methods, Searching for Trees, Rooting Tees, Evaluating Tres & Data Phylogenetic sofware; companies & patents, IPR issues, Patents, copyrign&Patetng References: 1 David W Mount, Bioinformatics: Sequence and Genome Analysis, (Gold SpringHarbor, 2001 2, Arthur M, Les, Introduction to Bioinformatics, Oxford University Press, 2002 ‘IO 5003 BIOPOLYMER TECHNOLOGY [4004] Biopolymers produced from various renewable resources, ccaractarsis, mars and demerits over conventional pohmers Biopolymers and Arficial Biopolymers in BiomedicalApplcatons, an Overview, Novel Synthesis of Biopolymers. and. Their Medica ‘Applications, Composte Flms Based on Poly (Vinyalcohol) and Lgnocelulasic Fbres: Preparaton and Characterizatons, Compost Matos Based on Gelain and Files ftom Renewable Resources: ‘Thermal and Mechanical Properties, Properties of PHAS and Their Correlation to Fermentation Conditons; Synthesis and modiieation of vanthum gum, PHA, PH Biosurlacants: Source, characteristics and properties of Blosurfactans; Production of Biosutactants vig the fermentation and biotransfrmation routs; Production of Biosutacants ‘wth immobiized ces; tegrated bioprocess for continuous production ‘of Biosurtactans including downstream processing; Applications of Biosurtactants ~Food Indust, Environmental Control, Material Testing 2 and Analyical Methods: Comparisan of Test Systems for the Examination of the Fementabliy of Biodegradable Materials, Suctue-Biodegraabity Relatonship of biopolymers;Case studies, Optimization of production and purfcation of Xanthum gum and other biopolymers ike PHA, PHB References: 4, Emo Chien’ and Helena Gi, Birelated Polymers: Sustainable Plymer Science and Technology, Springer 2001, 2, donnson RIM, LY. Mwakambo and N,Tucke, Biopolymers, Rapra Technology 2008. ‘BIO 5008 DESIGN AND DEVELOPMENT OF BIOLOGICAL TREATMENT PROCESSES [4004] Inroducton, decompostton of organic carbon compounds; Biology, Nass, energy balance for aerobic &anaerabic respiration, Aerobic and arazrobic dacompostion of glucose, proein, carbohyérales, Ipds Nitrogen removal, phosphorous removal, basomtion, Parametrs effecting tha bilogical treatment: MLSS, MLVSS, F/M rao, BOD and sionfcance, Model andfting Kinetic parameter Least square, Fujimoto, Daly ciffrence, Thomas and Moments-Methods, Activated sludge process - plant configurations; Modeling of aerobic waste water ‘weatmentprocess; Design of activated sludge process for BOD removal, Niutication & Deniticaton, Design ofthe tna (secondary) clair, Design of SBR, Reactor systems fr anaarobi process, Dsintcto various methods, CHICKS -WATSON EQUATION AND APPLICATION ‘ater reuse Processes involved, rsk assessment, Water Reclamation “Technologies, Industial waterreuse Roterences: 1. JordeningH.J and J Winer, Environmental Bitechnology- Goncepts and Applications, Cambridge Univers Press, 2006, 2 George Tehobanoglous and Franin L. Burton, Wastewater Enginering-Teatment, Disposal and Reuse, Tata McGraw Hil Publishing Co.Ltd 1990, BIO 5005 ENVIRONMENTAL BIOTECHNOLOGY [4 004) icrobaiora of sol, grow, interactions among soll microorganisms, Diogeochemical role of soll microorganismsSimple_ aromatics, chlorinated, polyaromatic, petroleum products, pesticides and surfactants. Waste water characterises, biological waste. water ‘veatment, actveled -slidge grocess, mathematical modeling of anaetobic-cigester dynamics; Biotechnology processes for oll Bioremediation processes Ulva filtration systems for waste water ‘contaminant removal: industral waste eatment opportunities for reverse osmosis and utvaftration Blo-hazard Mantoring and Conta Energy recovery systems for urban wasta gasification of wastes fuels and chemicals from crops, production af all rom wood waste, fuels ‘om wood wast, methanol producton; Renewable and non-renewable resources, Blotecmologial inputs in producing good qualty natural ‘ies Treatmentof municipal waste and industal efuents.Degradaton af Pesticides and otter toxic chemicals by Microorganisms Thuriogienss toxin as 2 natural pestcide Biological congo af other insects swarming the agriculure fielés. Enrichment of ores by microorganisms Biotrlizers Nirogen fixing microorganisms Reterences: 1. Foster.F andD.A. John Ware, Environmental Biotechnology, Eis Horwood Limited, 1987, 2. Larry Anderson and David A, Fuels trom waste, Tilman, Academic Press, 1997, BIO 5007 IMMUNOTECHNOLOGY [4.00 4) Innate and adaptive immunity. Lymphocytes - ther origin and

    You might also like