NAME OF CLASSIFICATIO MECHANISM INDICATIO CONTRAINDICATI NURSING

ADVERSE EFFECT
DRUG N OF ACTION N ON CONSIDERATION
Generic name: Therapeutic: Increases force and Heart failure; Hypersensitivity to drug CNS: fatigue, Assess apical pulse
Digoxin antianxiety agents, velocity of tachyarrhythmi headache, asthenia CV: regularly for 1 full
anticonvulsants, myocardial as; atrial bradycardia, ECG minute. If rate is less
Brand name: sedative/hypnotics, contraction and fibrillation and Uncontrolled changes, arrhythmias than 60 beats/ minute,
Lanoxin skeletal prolongs refractory flutter; ventricular arrhythmias EENT: blurred or withhold dose and
Muscle relaxants period of paroxysmal yellow vision GI: notify prescriber.
(centrally acting) atrioventricular atrial AV block nausea, vomiting,
Pharmacologic: (AV) node by tachycardia diarrhea GU: Monitor for signs and
benzodiazepines increasing calcium gynecomastia symptoms of drug
entry into Idiopathic hypertrophic Hematologic: toxicity (such as nausea,
myocardial cells. subaortic stenosis thrombocytopenia vomiting, visual
Slows conduction Other: decreased disturbances,
through sinoatrial appetite arrhythmias, and altered
and AV nodes and Constrictive pericarditis mental status). Be
produces aware that therapeutic
antiarrhythmic digoxin levels range
effect. from 0.5 to 2 ng/ml.

Monitor ECG and blood

levels of digoxin,
potassium, magnesium,
calcium, and creatinine.
Stay alert for
hypocalcemia. Know
that this condition may
predispose patient to
digoxin toxicity and
may decrease digoxin
efficacy.

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 Watch closely for
hypokalemia and
hypomagnesemia.
Know that digoxin
toxicity may occur with
these conditions despite
digoxin blood levels
below 2 ng/ml.

MECHANISM CONTRAINDICATI NURSING

NAME OF DRUG CLASSIFICATION INDICATION ADVERSE EFFECT
OF ACTION ON CONSIDERATION
Generic name: Therapeutic: Blocks Management of : Uncompensated HF; CNS: fatigue, ● Instruct patient to
Propanolol antianginals, stimulation of hypertension, Pulmonary edema; weakness, anxiety, take medication as
Hydrochloride antiarrhythmics beta1(myocardia angina, Cardiogenic shock; dizziness, drowsiness, directed, at the same
(Class II), l) and beta2 arrhythmias, Bradycardia, sick sinus insomnia, memory loss, time each day, even if
Brand name: antihypertensives, (pulmonary, hypertrophic syndrome, or heart mental depression, feeling well; do not skip
Inderal vascular vascular, and cardiomyopathy, block (unless mental status changes, or double up on missed
headachesuppressant uterine)- thyrotoxicosis, pacemaker present). nervousness, doses. Take missed

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 s adrenergic essential tremors, nightmares. EENT: doses as soon
Pharmacologic: beta receptor sites. pheochromocytoma blurred as possible up to 4 hr
blockers . Also used in the vision, dry eyes, nasal before next dose (8 hr
prevention stuffiness. Resp: with extended-release
and management of bronchospasm, propranolol).
MI, and the wheezing. Inform patient that
prevention of CV: ARRHYTHMIAS, abrupt withdrawal can
vascular headaches. BRADYCARDIA, HF, cause life-threatening
PULMONARY arrhythmias,
EDEMA, orthostatic hypertension, or
hypotension, peripheral myocardial ischemia.
vasoconstriction. GI: ● Advise patient to
constipation, diarrhea, make sure enough
nausea. medication is available
GU: erectile for weekends, holidays,
dysfunction,plibido. and vacations. A written
Derm: ERYTHEMA prescription may be
MULTIFORME, kept in wallet in case of
EXFOLIATIVE emergency.
DERMATITIS, ● Teach patient and
STEVENS-JOHNSON family how to check
SYNDROME, TOXIC pulse daily and BP
EPIDERMAL biweekly. Advise
NECROLYSIS, itching, patient
rash. Endo: to hold dose and contact
hyperglycemia, health care professional
hypoglycemia (q in if pulse is 50 bpm or BP
children). MS: changes significantly.
arthralgia, back pain, ● May cause
muscle cramps, drowsiness or dizziness.
myopathy. Caution patients to
Neuro: paresthesia. avoid driving or other
Misc: activities that require

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 alertness until response
to the drug is known.
● Advise patients to
change positions slowly
to minimize orthostatic
hypotension, especially
during initiation of
therapy or when dose is
increased.
ANAPHYLAXIS, ● Caution patient that
drug-induced lupus this medication may
syndrome. increase sensitivity to
cold.
● Instruct patient to ask
a health care
professional before
taking any OTC
medications or herbal
products, especially
cold preparations, when
taking this medication.

NAME OF MECHANISM CONTRAINDICATI NURSING

CLASSIFICATION INDICATION ADVERSE EFFECT
DRUG OF ACTION ON CONSIDERATION
Generic name: anti-infectives Binds to bacterial Treatment of: Hypersensitivity to CNS: SEIZURES (high ● Instruct patient to

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Cefuroxime cell wall Respiratory tract cephalosporins; Serious doses). take medication around
membrane, infections, Skin and hypersensitivity GI: the clock at evenly
Brand name: causing cell skin structure to penicillins. PSEUDOMEMBRAN spaced times and to
Ceftin, Zinacef death. infections, Bone OUS COLITIS, finish the medication
and joint infections diarrhea, nausea, completely, even if
(IV), Urinary tract vomiting, cramps. feeling better. Missed
infections , Derm: rashes, urticaria, doses should be taken
Gynecological diaper dermatitis. as soon as possible
infections, Hemat: bleeding, unless almost time for
Septicemia (IV), eosinophilia, hemolytic next dose; do not
Otitis media (PO), anemia, leukopenia. double doses.
Meningitis (IV), Local: pain at IM site, Advise patient that
Lyme disease (PO). phlebitis at IV sharing of this
Perioperative site. medication may be
prophylaxis (IV). Misc: allergic reactions dangerous. Pedi: Tell
including parents or cargeivers to
ANAPHYLAXIS, use calibrated
superinfection. measuring device with
liquid preparations.
● Advise patient to
report signs of
superinfection (furry
overgrowth on the
tongue,
vaginal itching or
discharge, loose or foul-
smelling stools) and
allergy.
● Instruct patient to
notify health care
professional if fever and
diarrhea
develop, especially if

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 stool contains blood,
pus, or mucus. Advise
patient
not to treat diarrhea
without consulting
health care professional.

NAME OF MECHANISM CONTRAINDICATI NURSING

CLASSIFICATION INDICATION ADVERSE EFFECT
DRUG OF ACTION ON CONSIDERATION
Generic name: Analgesic ( Non- Paracetamol may To relieve mild to Hypersensitivity to Hematologic:  Assess patient’s
Paracetamol opioid) cause analgesia moderate pain due acetaminophen or hemolytic anemia, fever or pain: type of
Antipyretic by inhibiting CNS to things such as phenacetin; use with leukopenia, pain, location,
Brand name: alcohol neutropenia, intensity, duration,
prostaglandin headache, muscle
Biogesic pancytopenia, temperature, and
synthesis. The and joint pain, thrombocytopenia. diaphoresis.
mechanism of backache and Hepatic:  Assess allergic
morphine is period pains. It is liver damage, jaundice reactions: rash,
believed to also used to bring Metabolic: urticaria; if these
involve decreased down a high hypoglycemia occur, drug may
permeability of temperature. For Skin: rash, urticuria have to be
the cell membrane this reason, discontinued
 Teach patient to
to sodium, which paracetamol can be
recognize signs of
results in given to children

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 diminished after vaccinations chronic overdose:
transmission of to prevent post- bleeding, bruising,
pain impulses immunization malaise, fever, sore
throat.
therefore pyrexia (high
 Tell patient to notify
analgesia. temperature).
prescriber for pain/
Paracetamol is fever lasting for
often included in more than 3 days.
cough, cold and flu
remedies

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