Name Indication Side Effect Adverse Effect Mechanism of Action Nursing

Consideration
Brand Name Used in the Swelling Some common Amlodipine is an Assess BP (sitting,
Norvasc management (edema) dose-dependent angioselective lying, standing) and
of hypertension and Headache adverse effects of calcium channel pulse periodically
Generic coronary artery disease Fatigue amlodipine include blocker and inhibits during therapy.
Name in people with either Palpitation vasodilatory the movement of Monitor frequency of
Amlodipine stable angina (where ch s effects, peripheral calcium ions into prescription refills to
est pain occurs mostly Dizziness edema, dizziness,pa vascular smooth determine adherence
Classification after physical or Nausea lpitations muscle cells and to therapy. Assess
calcium emotional stress) or Flushing and flushing. cardiac muscle cells patient for signs of
channel vasospastic angina (whe Abdominal Peripheral edema which inhibits the angioedema
blockers re it occurs in cycles) pain (fluid accumulation contraction of cardiac (dyspnea, facial
and without heart failure. Sleepiness in the tissues) muscle and vascular swelling). 
Route Increase BP will lead to Drowsines smooth muscle cells.
Oral Increase Pressure to s
Increase stress will turn Itching
out to Increase thyroid Skin rash
storm Muscle cra
mps
Muscle
weakness
Name Indication Side Effect Adverse Effect Mechanism of Nursing Consideration
Action
Brand Name It is Cold symptoms CNS: Headache, Atorvastatin competi Advise patient that this
Lipitor used to lower such as a runny asthenia tively inhibits 3- medication should be
bad cholester or stuffy nose GI: Flatulence, hydroxy-3- used in conjunction
Generic Name ol and Joint pain abdominal pain, methylglutaryl- with diet restrictions
Artovastatin raise good Insomnia cramps, constipation, coenzyme A (HMG- (fat, cholesterol,
cholesterol (H Nausea nausea, dyspepsia, CoA) reductase. By carbohydrates,
Classification DL). Loss of appetite heartburn, liver failure preventing the alcohol), exercise, and
Statin/Anticoagula It is Indigestion Respiratory: Sinusitis, conversion of HMG- cessation of smoking.
nt used to Muscle spasms pharyngitis CoA to mevalonate, pain, tenderness, or
lower triglyceri with or without pain Other: Rhabdomyolysis statin medications weakness occurs,
Route des. Chest pain (angina) with acute renal failure, decrease cholesterol especially if
Oral Lightheadedness  arthralgia, myalgia production in the accompanied by fever
It is
and fainting liver. or malaise. planned or
used in some
Shortness of suspected
people to
breath or
lower the
other breathing pro
chance
blems
of heart
Severe allergic
attack, stroke,
reaction (anaphylax
and certain
is)Stevens-Johnson
heart
syndrome
procedures.
It is
used to slow
the progress
of heart
disease.
Name Indication Side Effect Adverse Effect Mechanism of Action Nursing
Consideration
Brand Name used with a proper diet physical nausea, vomiting, Metformin decreases Monitor blood
Fortamet and exercise program weakness abdominal pain, hepatic glucose glucose and
Glucophage and possibly with (asthenia) diarrhea) and production, decreases HbA1C, and lipid
Glucophage XR other medications to symptoms of malabsorption of intestinal absorption of profile
Glumetza control high blood weakness, muscle  vitamin B12 and glucose, and improves periodically.
Riomet sugar. It is used in pain (myalgia) folic acid. Skin insulin sensitivity by Monitor known
patients with type 2 upper respir rashes are rare. increasing peripheral or suspected
Generic Name diabetes. Controlling atory tract infection The platelet glucose uptake and alcoholics
Metformin high blood sugar helps low blood inhibition hardly utilization carefully for
prevent kidney damage sugar (hypoglycemi has any clinical decreased liver
Classification , blindness, nerve a) disadvantages. function. Monitor
Biguanide problems, loss of limbs, nausea cardiopulmonary
and sexual function vomiting status
Route problems. chest disco throughout
Oral mfort course of
chills, dizzin therapy
ess
bloating/abd
ominal distention
constipation
heartburn
Name Indication Side Effect Adverse Effect Mechanism of Nursing
Action Consideration
Brand Name indicated to improve pain, redness, low blood sugar, Insulin glargine Monitor for S&S of
Lantus Solo glycemic control in swelling, itching, or problems at the site differs from human hypoglycemia (see
star. adults patients with thickening of the of injection, insulin by replacing Appendix F),
type 1 diabetes skin at the injection itchiness, and asparagine with especially after
Generic Name mellitus and in site weight glycine in position changes in insulin
Insulin Glargine adults with type 2 headache, gain. Serious side 21 of the A-chain dose or type.
diabetes mellitus. hunger, effects include low and by carboxy-
Classification blood potassium terminal extension Lab tests: Monitor
weakness,
Insulin Analog of B-chain by 2 fasting blood
sweating, arginine residues. glucose and
Route tremors, HbA1C periodically..
Subcutaneous irritability,
trouble
concentrating,
rapid
breathing,
Name Indication Side Effect Adverse Effect Mechanism of action Nursing
Consideration
Brand Name in patients with swelling, nausea, Severe adverse Propylthiouracil inhibits Advise patient to
Propylthiouracil Graves’ disease vomiting, reactions include liver the production of new report sore throat,
with heartburn, loss of injury presenting as thyroid hormone in the fever, chills,
Generic Name hyperthyroidism or taste, joint or hepatitis, thyroid gland. It acts headache,
PTU toxic multinodular muscle aches, Inhibition of by inhibiting the malaise,
goiter who are numbness and myelopoiesis enzyme thyroid weakness,
Classification intolerant of headache, (agranulocytosis, peroxidase, which yellowing of eyes
Antithyroid Agents methimazole and allergic reactions, granulopenia, aplastic usually functions to or skin, unusual
for whom surgery and hair anemia, and convert iodide to bleeding or
Route or radioactive whitening. thrombocytopenia), iodine molecule and bruising,
Oral iodine therapy is drug fever, a lupus- incorporate the iodine symptoms of
not an appropriate like syndrome molecule into amino hyperthyroidism or
treatment option (including acid tyrosine hypothyroidism, or
to ameliorate splenomegaly and rash to health care
symptoms of vasculitis), professional
hyperthyroidism in periarteritis, promptly.
preparation for hypoprothrombinemia Report S/SX
thyroidectomy or , and bleeding agranulocytosis
radioactive iodine
therapy in patients
who are intolerant
of methimazole
Name Indication Side Effect Adverse Effect Mechanism of Action Nursing
consideration
Brand Name To control nausea, itching, rash, prevents iodine and Advise patient to
Tapazole thyrotoxicsis in vomiting, upset hives, joint pain peroxidase from their normal report sore throat,
Grave’s Disease stomach; and swelling, interactions with fever, chills,
Generic Name and toxic Nodular headache, fever, changes thyroglobulin to form T4 and headache,
Methimazole goiter as dizziness, drowsine in taste, nausea, T3. This action decreases malaise,
definitive therapy, ss; and vomiting thyroid hormone weakness,
Classification pre- operatively production. Methimazole als yellowing of eyes
numbness
thionamide and along with o interferes with the or skin, unusual
or tingly feeling;
antithyroid agent radioactive conversion of T4 to T3. bleeding or
iodine. rash, Since T3 is more potent than bruising, rash, or
Route itching, skin T4, this also reduces the symptoms of
Oral discoloration; activity of thyroid hormones hyperthyroidism or
muscle or hypothyroidism
joint pain; promptly.
hair loss; or.
decreased
sense of taste.
Name Indication Side Effects Adverse Effects Mechanism of Action Nursing Consideration
Brand Name Cardiac feeling tired, Cold extremities, preferred agent for β- Obtain careful medical
InnoPran XL arrhythmias, dizzy or light insomnia, fatigue, blockade history to rule out allergies,
especially headed dizziness, vivid in hyperthyroidism and  asthma, and obstructive
Generic Name supraventricular (these can dreams, nausea, thyroid storm due to pulmonary disease.
Propranolol tachycardia, and be signs of a vomiting, its additional effect of Propranolol can cause
ventricular slow heart Weakness, blocking the peripheral bronchiolar constriction
Classification tachycardias rate) cold paraesthesia, conversion of inactive even in normal subjects.
beta blockers induced by digitalis fingers or wheezing, T4 to active form T3
or catecholamines toes pharyngitis, Monitor apical pulse,
Route Unlabeled uses: (propranolol bronchospasm. respiration, BP, and
Oral Recurrent GI may affect . Depression, circulation to extremities
bleeding in cirrhotic the blood confusion, closely throughout period
patients, supply to cognitive of dosage adjustment.
schizophrenia, your hands dysfunction, Consult physician for
tardive dyskinesia, and feet) emotional lability, acceptable parameters.
acute panic difficulties fatigue,
symptoms, anxiety, sleeping or hallucinations. If patient complains of cold,
CHF nightmares. painful, or tender feet or
feeling sick hands, examine carefully
(nausea) for evidence of impaired
circulation. Peripheral
pulses may still be present
even though circulation is
impaired. Caution patient
 to avoid prolonged
exposure of extremities to
cold.

Name Indication Side Effects Adverse Effects Mechanism of action Nursing consideration
Brand Name used to treat burning mouth/throat, used at low doses and to decrease Lab tests: Determine
SSKI overactive sore teeth/gums, for a short time (less thyroglobulin serum potassium levels
thyroid and to swelling inside the than two weeks). The proteolysis, thereby before and periodically
Generic Name protect the mouth, increased most common side decreasing thyroid h during therapy.
Iodine thyroid gland saliva, eye effects are on the ormone secretion.
(Potassium from the irritation/swollen digestive system, The resulting slight advise patient to use
iodide) effects of eyelids, severe predominantly reductions of T4 and a straw to avoid tooth
radiation from headache, swelling of being gastrointestinal T3 concentrations in discoloration.
Classification inhaled or the front of the intolerance serum cause
Anti-thyroid swallowed neck/throat (goiter), and its bitter (metallic) transient increases
radioactive signs of taste; thus, the of thyrotropin (TSH) advice patient to drink
Route iodine. decreased thyroid gla recommendation is concentrations in juice after taking
Oral nd function that it be taken with serum. potassium iodied
juice or milk to protect because it has metallic
against gastrointestinal taste.
irritation
Name Indication Side Effect Adverse Effect Mechanism of Action Nursing
consideration
Brand Name Treatment and Low blood Hypotension Calcium Observe patient
Citracal prevention of pressure Headache citrate increases closely for
hypocalcemia. (hypotension) Constipation plasma calcium levels. symptoms of
Generic Name Adjunct in the Nausea. Diarrhea This hypocalcemia
Calcium Citrate prevention of Flatulence reduces calcium flux (paresthesia,
Vomiting.
postmenopausal Hypophosphatemia from osteocyte activity muscle twitching,
Classification osteoporosis. Low blood Hypomagnesemia by reducing the laryngospasm,
2-hydroxypropane- phosphates secretion of parathyroid colic, cardiac
1,2,3-tricarboxylate (hypophosphatemi hormone (PTH) arrhythmias,
Route a) [T36]. Calcium does this Chvostek’s or
Oral Low blood by stimulating a G- Trousseau’s sign).
magnesium protein
(hypomagnesemia) coupled calcium recepto
r on the surface of
parathyroid cells.
Name Indication Side Effects Adverse Effects Mechanism of Nursing
action consideration
Brand Name used to treat increased Adverse effects the hypothalamus Teach patients
Levoxyl an underactive appetite. (frequency secretes about the many
thyroid gland weight undefined) include: angina thyrotropin- drug interactions
Generic Name (hypothyroidism). It loss. pectoris, tachycardia, releasing with levothyroxine 
Levothyroxine replaces or provides palpitations, arrhythmias, hormone (TRH), and about the
heat
more thyroid myocardial infarction, which then importance of
sensitivity.
Classification hormone, which is dyspnea, anxiety, fatigue, stimulates the establishing a
Hormone normally produced excessive  headache, heat anterior pituitary daily routine to
replacement by the thyroid sweating. intolerance, insomnia, to secrete thyroid- help maintain
gland. Low headache irritability, diaphoresis, stimulating even hormone
Route thyroid hormone . skin rash, alopecia, goiter, hormone (TSH), levels. Levothyroxi
Oral levels can occur hyperacti weight loss, menstrual which ne should be
naturally or when the vity. irregularities, abdominal subsequently taken on an empty
thyroid gland is nervousn cramps, diarrhea, emesis, stimulates the stomach with
injured by ess. reduced fertility, and thyroid to secrete water, at least 1
radiation/medication decreased bone mineral 80% thyroxine hour before eating
s or removed by anxiety density (a result of TSH (T4) and 20% L-
surgery. suppression) triiodothyronine
(T3)