To create the Policy in the DSM go to the the Policy tab.

Policies – Click New Policy

Give the name for the Policy and we can choose the base policy as inherit or None.

We can place the new policy to the computers directly.

In Case if we choose NO then we need to select the policy from the computer console.
Next we need to enable the Anti-Malware and other protection on the policy.

Next Remove the Default from the Real-Time Scan option and Select the Malware
Scan configuration. Click Edit and create the new Exclusion Rule.
In Schedule always recommended to have it Every Day All Day option for the Real-
Time Scan.

Select the Files and Folder as per our company scan exclusion policy.
Select the Extension Exclusion and the files extensions as per the requirements .

Next Select the Actions and choose appropriate actions .

  

Once the policy is set then next go the computer and select the computer in which
policy have to be applied.

Note that  we can apply the policy to the group of computers also.

Go to the General – Policy – Select the Policy which we created ( TestPolicy )

Next Go to the Action tab and Activate the VM.

We can check the status in the General – Status section which will show the
corresponding ESXi and the DSVA information.

Once the policy is applied , We can see the computers using the policy in the Policy tab.