Syphilis 2.

Primary headaches
1. A painless penile ulcer followed 6 weeks later by a maculopapular rash and 3. Diffuse lymphadenopathy
generalized lymphadenopathy 4. Hairy leukoplakia
2. Painless chancre – firm, button-like that ulcerates and may become crusted 5. Kaposi’s sarcoma
a. May resemble a carcinoma or crusted cold sore a. Multiple forms (macules, papules, plaques, nodules)
b. infectious b. Multiple and may involve internal structures
3. Rash – ham-to-bronze colored, generalized, maculopapular rash the involves the c. Malignant
palms and soles 6. HSV
4. Pustules 7. HPV
5. Condylomata lata (raised growth resembling a wart) 8. cytomegalovirus
6. Alopecia (moth-eaten) 9. mollluscum contagiosum (water warts)
7. White plaques on oral and genital mucosa 10. mycobacterial skin infections
8. Gummas, granulomas 11. candidiasis
9. Onycholysis 12. oral and anal squamous cell carcinoma
10. Hearing loss “whisper test” 13. psoriasis (severe)
11. Small, irregular pupils – accommodate but do not react to light 14. erythroderma
a. Argyll Robertson pupils 15. seborrheic dermatitis (severe)
12. New onset dysconjugate gaze 16. acquired ichthyosis
13. Hutchinson’s teeth
a. smaller, more widely spaced, sides taper Raynaud’s Phenomenon
b. notched on their biting surfaces 1. CREST
c. usually upper, central incisors a. Calcinosis
d. congential syphilis b. Raynaud’s
14. mucous patch of syphilis c. Sclerodactyly
a. slightly raised, oval and covered by a grayish membrane d. Telangiectasias
b. secondary 2. Dermatomyositis
c. mouth 3. Rheumatoid arthritis
15. quotidian fever – fever reoccurring daily 4. Scleroderma
16. Hot cross buns skull 5. SLE
6. Transverse linear depressions (Beau’s Lines)
Parkinson’s Disease
1. Masked facies Psoriasis- extensor surfaces
2. Drooling 1. Silvery, scaly lesions
3. Facial skin becomes oily 2. Pustular psoriasis
4. Decreased blinking, characteristic stare 3. Plaques with scales
5. Neck and upper neck flex forward 4. AIDS
5. Reiter’s syndrome (psoriasis-like lesions)
Systemic Lupus Erythematous 6. Onycholysis
1. Nodular episcleritis local redness on the sclera 7. Pitting
2. Malar/Butterfly rash
3. Photosensitivity Liver Disease (Cirrhosis)
4. Discoid rash 1. Jaundice
5. Alopecia 2. Spider angioma, other telangiectasis
6. Vasculitis 3. Palmar erythema
7. Oral ulcers 4. Terry’s nails
8. Raynaud’s phenomenon 5. Pruitus
6. Purpura
HIV/AIDS 7. Caput medusae – dilated cutaneous veins around the umbilicus
1. Risk for melanoma 8. Parotid gand enlargement
Hypothyroidism
1. Dry, rough, pale skin
2. Coarse and brittle hair
3. Myxedema
4. Alopecia – lateral 1/3 of eyebrows
5. Skin – cool to touch
6. Thin and brittle nails
7. Dull puffy facies
8. Periorbital edema does NOT pit with pressure

Hyperthyroidism
1. Warm, moist, soft and velvety skin
2. Thin and fine hair
3. Alopecia
4. Vitiligo
5. Pretibial myxedema
6. Hyperpigmentation
7. Onycholysis
8. Weight loss
9. Lid-lag test – rim of sclera is present even when pt moves eyes downward
10. Exopthalmous (from proptosis – abnormal protrusion)
11. Systolic or continuous bruit
12. Poor convergence
13. Characteristic stare
14. Joffrey’s sign – lack of wrinkling of the forehead