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Vy MEDICINAL CHEMISTRY-II ‘Swiety As Per Syllabus Prescribed for 8. 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Marta for ep commen geo Wee ts bok wl eave ede impel nk forward a mee te ‘Above we waldo thnk out energean jaric Publishes Sh PA Janand Me Viasat Wi Vaan Campany reggie oak chapter cote outers spers caper Cote Chaptert (apes CONTENTS Hsin 12 Histamine espe 13 Anite aes acini ets tam: 3 21 ndacton 322 Types of ane, 23 Call ge in cane 24 lennon cf ethape gu 29 Og agnor e731 Aig ae 41 Iorodection 2 42 Caen 2, 21 Caton ‘hte 22 Tider¥6 2 Lop stir 9, 24 Pats ‘pang dees W425 Oro dus 1 Anshypresve Ages mom 5: Hypertension 18, 52 Aniypneive drgs 18 521 Avene ‘pit anapit HL, 522 Anglsm cometing eye his 115323 Cental cing ane dap 19, 524 Vata 1 525 Aceon ten ing gets 7, 5:26 Dit 10, 527 (tim canal es Anahi Agen bes {1 Ayia 62 Anat ets 16 Anthypetipdemi Agent wie 71 Inadstin 10,72 Loin atl 1,73 Drag egy “secarg ipopeten mets 11 Congtat nd Aniconglans tem 1 Machi of od coguson 16, 82 cicton of rg od teeing dcr raged in Congestive Het Faire mens 91 Congestive et ae 191. Types of CHE, 92 Drags wed espe et le 92 Cad ode 922 Nee 1h 3 oct 924 Fc pray sem 9059 apo seas ssomids pang als sumseny ype among meng “apuaonmy KAMP doy AEP sparsamrpH IRRORARPOH “SPEND SPL PRO a ee ‘eobpunynnpacny apaps sero ma “omsnpern were Sree pada Tanden MOTE BEIM SPD ‘aeampal “ase pgs ww aati ‘snisay sae Ky eRe esaesy n-unsn amen SUSAN wed sony neds tase pe “apna ese AN UDO RY ‘some ‘ompumany emo aeons “aemdadeanye IeeMTY eon nn pgm aMHON SmeNOHAD ‘aeerMPN sy Aime ‘ney amido cry someon aera redone aoyau dy 04799 cappy apo “aupREUT sey CH emperor zamena aE “MpEN] "OMEIY ‘RS SEY REM Sepeinondiy seam semdomst “gpueqeoipiy Suze) HM ee ee ee fuzeng eeuaRPORSY AE, FUOREANGY euPKNR_D “HEATH seumsdu spumrenmiy omalysisig ‘wm au) NE smumieog mRNA ‘apPONY mE si psn ag eeengane poe alo anes 8 SURREY SnavT1As «@ Sudesong We Serpe uo) ce stein soe amg We Sone OST TE exer, oragesy joer ee ewes 1x sw fey 4 ‘ae soon wean sow apegmpey egy (2: cup pst pe pi cot ‘3% spasm yout sues (U0 $0 LOANED spat sur assem 95 ENT HBL Aste iv anne upd mga pg COL WE emp ace wos omoepag wo Sas Bc of ise o INDEX w Aone sus ding ges ‘Arse cept ingen Anges eertng eye os ce ian) Ane emer deat ‘Aassngaal dp ‘Asari gets (asian hazel drs aban ante ion arise py Cale nce Cen cg tee gs Chante ofa el al ates ‘Cole sbi ike ‘Gis mentrane eps dg dae ken) (Chas fs ing gts si mplzton pln have! Backers) hsv nts ane ake ‘Gaston of cence pts Gsicaton of dps ed ting ses (Chsteton of snes ‘Cg at ae Conostoie w m 10 o ry % ra au 25 a we © —— Soap gi soenngs pc a sup psn epg, — men w sop As sons xeon or Sasxonpear amon net eons pans “ere sep nna, enueme so Soe ow « ona dnd ay or ‘Stamp Sade ens » ‘sate somour we pea en, @ so Spm sous, we suntan 7p, © tz ‘aio 0 m ep oy a eR wo a 0M 0 oH v0 mets po sa oo “ ‘romp daoy se Soper et ot swsyoqna weedy wa org serena dy fst sa se pein pe ode ™ wa Somos uno mz senda 5p tor, @ ‘Specs fo see aap oom we o SF naniodig smd end ido ante ey seer w va ns aus pe sag ssi ous om yy “ ‘6 np Si sag, 1st ‘mci updo fe ag, @ w Anypetenive Ages: Tint Cpl cpl, Bape ene Ideclride, Quine ydrchlo Matyptydehide® Cn Iydiodrid, Gnade movaniph,Guaene aay, Selim nitoprie DizosdeMioxl Reserpine idee Astaythnic Drags: Quite spate, Pine yc, Dapyranide phi, Phen sodlum Licike Hyde, Toca hydro, Morne econ, Leribe, inde Sl Antiypetipidemi gent Clb, Lost, Clariant Covguint & Antcaulans: Meroe, Acton, Wate Anankioe, pg ‘rags sed in Congeive Heat Fallre Dig Dion, Neste, Benn, osrw Drags Acting on Endoine System: Nene, Secochemisty nd tan of ‘Sex Homoner: Tero, Nandos, gins Osi, Osta, Osta, Diya. Drags or Eee Dann Sea adh nl Contcepives Mien, Neg eon Corot: Cortona, Hyer Pesacane tines, Destine ‘Tayi and Aatthyrid Drags: Thyra Ty, Pythian Ansiabet Agent alin and spp, Say es: Tati, Croan, pee, ep punto Morin, ThacitonesFoghiazone, sgn pitas apple, tpt Chess inkinrs Azan, Vopr, {acl Anesthetc: SAR oats Bewsic acid ete; Cece, Heya, Mapping, Cycomethyxin, Pprcine ‘Amiso Bensoc ald Desnaties: Bz’, Baanien, Pein ute, Propogeain Tei, Benoit, ‘drain Aide Devt Ligne Mpa, Fb, ese, Moreamous: ita Digeraon Dune” | al ANTIHISTAMINIC AGENTS 11:1 Bota meats uni pid apt pnp at nd Soars soy one ce salah psi eaee hae ee _womatic amino aid deortonyase ~— aa Hae pas De pe oN {250 iy sins ios voy any 24h noes Fe Gung eae f mm et seen EE pay on “ese say SA a ERS WN fe sso ts oe ope eso ‘326d fess pre sty ess MY Se my Pel Sou spon ently rae pane ane 30 nen emmy go ene sige ened op eg ssn ae FH elm mind pom pummel ‘INGO Soames En Ha eS 1 hy zoom encusay covaisarrane satan [owas Aw ‘nina! ? wood ‘TRASH WOON HCORTGY AT Zs Sense, stn ef ern ses 6 sng sl wha ok hl mp so are Nour ens may theme Od vats au ie pal sac WOM i eth mat ora | pee“ Ste sts ane cp sy, ae ate weg ary | sp dd an tamndea inse (oS mat Wn, | pina, pine aca yl mend ey isa ta mas md | Syms on ce ‘eter aun ira ed tbe eas iain i ‘pet hn ti tne mp stp Te aan nth enmstaune aces titi ve Boe deol ind ied The ses gmeron apes we Aevum eel i etn agus bth bee med be mea ‘hemes imu nti dren sons 1.4. 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Thy fase anyhoo uri won| {Gs Kine, ain, and once a tht ptt heel Meck eh sol ss om te Nr aes swing te tin pa og ee (sine algae Hic0 UAC sane Gatien aribonb222) etn 290 Mehmet tt sipurciat te das Ni ae by Binge cen an ho, Te del Ne cy it he ‘year ere pe «date ptt and she al ottawa em Tae combed cerns penne Sopa ef eee "ss eps te neat af ope ad = er nates ap oman inteSAnoce Tat cen restr, Du te een oat une ‘pa ees seen perme nus aN he Sige ps, hoe depen hich drone conduc ty This chown a Pele “woe iam pr woe) “wp um pn ip pt ua ug San gy Py “rng a pu woop ed moins peg ron pares spe Saeigae aps NNN Kaan ok om paso pot roma» Sep gam py peut nese Se Pmne Sazanian dou seme FEED =n ope od en fp og een prose Po unpre oman yp on ps vn ae rp 238 wo HD sp no ene fl on ser Fi) ON) ‘Son de op say “ease frase sm me ome roo a sp span a ew Se NS HO a 11 apm pr zene us Bp oqo Yt Ml ops, rebel anemone» ipoouumidodont* servant we el ae wn oH arated opemidena pms sp aq nye aspen sours may pnprpnenmmas qua pes moan cm fe tao us ny ut po td ar ee cee sep uy Seng oe 29 nf omg onsen po sr ones pe pen SN 2 ems yeti pp ace oo 252K med TN Spremerailisey = aunt wronmeod Jo wseron saa fo Pre Su sommes wwe ae arp Faron = =peRemn Sper eet Buse Gj sepa oer aR REN a) por Smt pa soso eR PM PS repose nceongaoorm nana 3A, om nH sot 0 ° ere arg ‘yang ee oy EI Ha SONNE reonnd am Skg sne gon pre soe ap ron Hm sora ar esarg mr pip soNa m amO ON pu eo gs Stan age yans por pn 8S seo youpenb pr aptmbiane 2.2 SIREN sab Shane my paren bow feo somal sapere ‘ay yo ns mms amy ap a a oat ete se poe yp ga eS PRA AED 2m soe ape nyse dn ones Sup me ee ee soup rene Ire wor aya oar spin suedoprease a SO aa FAA SWaRO WHEN DOOR DALY TE a enn QO oy om, te at," UrAC anette oye Lian teste seat memban by ning he ve ws pe othe ft i oto ul by efing ial nstmaon Lae tes ‘pal cecson onc y Bcng eft ogee tum che inthe ‘Seal eben at ees ipl pou Vth cn Das ‘Teton the por cum wilt epee wl fo wi on Fm Tis ee snes et hy ot ape a om Fomsing ie inttby bring ti trina gute ment gi i aif 15 30 int ad piety is N ‘ayn et marge lowe by sect bas nb ‘tend diye hn. For rf of el reo act yin cigs ch eres itn ates reponl aes by pipe! seve Hc i sh ‘Nhl lan rel yal eal ish na el pit The ese te of Moraine nace me ad ot popes Hat pein nal he al perc tem ht Teel ro en top il seas psn see coe lil lad pip see ayia soi HP N. oA OO TUPAC name Spey 24 nian ain at anata chins on hme cl sub gt pd fe “city and mung sue propo By fringe ef an ners phere te te see dels ape prey ued ty ese seman et ‘oneal gs pte of memban sien ge The mate ‘ect a pti pion at spe. La of pate ton ee ‘ral ia a fom dai oe ta mee ‘Phen meth iy sw an predoninnyiae tma yonn by ‘te CVE ty fey to pond ace mete: Pa nce ‘ora naa a ae agen iy he mp eae Sp onpiont pny sun apa 75 eT ee eed hep ely he pao ete ete cnt af eat nlc gen mall nd compl pt python, ‘opr saan pein ad one fe ein i lg — ‘aha meat sm ony soaks x mame ‘Gey opps sepa em pm ht -sryondor ot opso pao ase ve op FaNae ee, rg pm asp «pos ep AE es oe ‘Sut oq wtbey we apes meen ap meme see mein ag somo ones} “33368 TN 1D Fo" SD He ell por snd wx sola mn apa po ep agus {ret sere ma Seat ey sy py perso SPE 1809 eA ge MN 9 oops ope exons marae OS amnd dado) ae gheadoorpy sweet “OO rome apeean, 2 ater Pergamon anon rand po pe RE et str pupiqure aie png! soe mmmaniraiig por saoenatoneed ome Pe soaty serena pr enya pre ens oma ‘estore seem 00 eo omega som nd og ve ey ne {ppm sou sms used aque Br ae mae pH 2 (avast ming se Ta) OEM eS a= Sinead Sump ue be non 9 Seep a ov ws 9 as a anes pon EU 2 TO -rereandtoneniointiesoa anes seman 40. oe se puro sree sponds mouse pn corey urd “exodamer u mh a pan Si PD SP ‘rung owed ppl ag wee eyo paras ogee tian pain Pray Han OS on pny Seger anen omeeEN ISHS ‘on ei pu at ey dy 9 IN eaten ‘soon umorto 3p ga pra ne png eames ea qa esl su peng omen sar Sopa po {ita pao ue sg ms ao perme ey, “rere roena coment ama vee “spon eospsy sprue Taya = ‘FikiSwm@ weoaN 309008 GLY Ae ig eer earners {hie wd f hep steno ent syn an cain i puis wi peut stor cottons yer thea and Wal Fain Westin 622 Cass tf Aone bck gots oder Hsing pi ck he rf heya oct en nthe frees of eran i ymin The donut etoposide "Seegeyehne can fs hong recep ce Drs ith as aa ‘resend ey ssl rape Sie Age ne eng o ehnt ects popes wich ue dna ry, eel conn ‘bcm pga fre ay Fe Papal TUPAC ame pale soy fn? aspen (eau lor Sang pent a Mc ol he optic rte inthe ‘ceo cotan cis ayia. Tl dominant dps te pe ‘nee end sn ni egh rp ae tat 1s ea antic pay fr he sient of spa yh, ising as ote, Paonia Super canons tala Popa! a npr oh live ee Gen of ihn! vee sas 162.3.0as m Reparation roboaton (Chm! Makes) “dyin i cae lpn th rc he ai el Ti a2 lwp hte recy pr be to tytn ‘et thug pas fe sn pty kings as reason AGENTS od hana gi C URAC sume Hy sbawtsan 4 Dldedytnaeltagl3S apt cm, Mos Ines uu mani acon ht rales atl eg ear i whch ‘duoc and ep ae ated [Sc i we ca, ut ‘hebainde tp da age ‘Aina neil me ate erie PIS ane 1 edn, ‘ean ct he eto meres ter dap Te mer tah aia = ‘etyunioduowe DEAL wc ako hs snare popes The eon socrne x aly gp ong eet rt eae aioe For ent oe ting et ayn a bayer Annus Masson aft ning many ent an ste ae iit ‘ttn og ced by nate maz eye tae isle ‘Sree an aren hasan cn tht arenes Hye es inp ‘Ses tig arn Te pooped ex bn opp oer oD eum mene UB) bined ncn fe Sol a eg dine ay Aaa ieee td de gy of “eine tap antes = yore oy PACnane Hyssop) linear & | \ ora eda} sn wpa 0 a eo N28 “mg aenoy hi pap ee He 9 re ‘epee ery So pe a ‘esr noua prsmee aperansy e ‘we cua ey pp tO Ho se S98 om p20 a mH A ey “Anes neaarer eager 504 ome aut wna 0 iy rl aeons on PPM ABA NIE STimonnaerspan ioe mane eeeiec er ee wr ool aeons ‘SNOUSIND BSH HOH HOPED ID NGOPSDPIONDND-O ‘SIoMsuy oor wae sermon , sow wu 6 rea el emma amour roa esepioae 3 roma ley ‘sarc edd puna mw nae sen ED ipa mason ‘omen ine cn monte u-anaon ‘eee sap — mag apg ne Seman sp Set SO oe =n © ‘roe ntem a west non pe aay ea ame ore teak men mama ope yy scene costar 6 seaman ree on 1) ‘Sioussr0sa0Ko NaNO soo meaty seams —— SUONSOND MOY (Ere aimee esp ma mg SPOR MINED DAD Fey aos ren Rena Bap NRE My ‘Serb pss p29 35 en es ‘en snow amg nee Surah pon oper na Se "ASRS WRI IO NOOR DLW TT gay ol ey deg {ons ANSE qUESTONS 2 ity aya ih als And Ch ae (02 Adtamteo tent ANTIHYPERLIPIDEMIC AGENTS PL NTRODUCT yrds he ns eae inter tpi abcd et se 16 tem wet ceed pms leo Ip ht a analy he oe popokins Upper saconoledes cng of i sinc (tent ied) n-ne end wth pon an tye Teenie ‘he pind pent th fm mingle pgp in the pa Each ‘ssl wih asp Kn a pgs. The vu pei nd Psa cnt peed yall tu ino doen, ey ody pep (ULDLunmene ety pepe DUS ey Bp CD and ety ppemin HDL The eso pam ncn of es scoped own at bypetpdeta co lie ree pom fhe psp ob ec in te Md, yp i es een contin fas pct moe aon wn ar ypediepeninnd ‘eon sc ith steno rt ae Ini dps te py he ipl ad poe mesa rm te ape comloes Ath hein angen elisa ttn ehr rom dort athe ies rome he. Ratan pn psy et a hy depot terra Fuerte, held eae eno pds Be bly lr det dass sertiy fom enor ence The pid tempor mans ht es shut cen and geile son ee ice, ® ree mmo 3> fy eestor Eee EFL sesso 32 faq sme om pled ze mem neo 3m) SEEN Yoyo TEL ound aoe anode ‘sen pr eprsp d w pp meas om pane ne equ maddy ing nenpa pt emng 2 y sty sos ovapy seem an od eee 2 sen ae aoa YS ae apa ae a pg me a 96 PH Ta SNE MO ‘Se eno oy nee DD 2m oT ek ee eee Repo nso] 9 sa pr arden po =p I eR LO ‘sada ogee a4] LP HN are xT us SOD a Serene ep “ups pamper e pes NE Fe IE Sey em spe sendy el PHI ar wy pode ov won i utes ee prep (FL mn Ny pee a py ans pl ed ge 0 “sur ane a ceo pad ‘esol vag pm cadena oe es FE HY FR LN por 21 Pe vo smile 9g aueuo ag se mom He Pe TED cy ‘anode amd dy msde nomen pene ep 2elne = 10 pgp iv ae aie ag a lh my oem ea Fpetp a maces ong ma om {smote pron oe Boy FO ON Ee po FE ay pn RE a ‘Son pe lar gy ul eed os ‘ened om mon pee Sr eeu yon fase ee sede mad Se por mga oo de i sng wana ne ges pe i oun oN Ph “nn ue en 8 SP Pwo ND PPR ea ‘me pura pa ene Pave apr py mma, eae po aay ASSIA ‘ars Wirraan a0 WOR DEY Te Be 72d gyn ts nies Nt 735 Chala arin bine Extn 3 A ext 800K oF MEDIAL chen 72.4 NM6- od reuse nib) he depen and of HG ea 9% with tec mera Ste yw ie sc op sd rn Maw a we Ape Irs Thscomoan ar egal tow sin a tonmed at es ne than ot me pon a mere 1 Thea MGR sen te hy teeing eet wn ing behind he egitim ee i ae. 2 Tete gol te pd wth ter Upp gr aed at ed ape ‘Seat rngepens wring oe neat emp 5 Pantin» sngopond pny cd wil « tying! pry, ech moe dep ene ratte or snes. Pp ato is end ‘yep peers it the pup memos pho! cae ‘sec ar bp aes, rc nt at sen ‘rar andtrain 4 Templeman bg ing wih ros ea ise a the elpmet ef atvatate (used py, rest lt) preate (uml ad sai yi) 5 Mai sna ate pot ne aye, Sint pe an att. ArTwrpeRPoeM AoE ox nko of Cok case wept leet es ye id ecnds ‘tion of cen hayhos shannon of rajer-amtaed LDL pane ed ‘ein f VDL pans vl acd HG Co ae ‘ey Gols tates ino oar ese es oo doses ete alee Conpersaty eens wel in enn! cpio hak Heo ‘ection aLOL eps The et mat ol hse fs gt at enon ‘eel as iia poet Lape tn nad Ioweigof po LDL tov IUPAC mame 1237, Aono ney 2 ent dao tan apt e {rain pt mathe by CDA ye othe mae ae ms, be dina ert yng Sere tritetn dtutn ethe at onon cnglin weet se n t hse ‘cin wea set Apyoiatly Seo Wh patens nee Inari cae pice ket: bnen, ee an Ew dep Sos of ysl an epg tee i ah or ca dane a nes “at cee pape th al Ge mpg me ee ‘mee i paige 2 em nines po astra po malin 9 lo) “pernto ioegp xy ae ee ses asa po 08 pg sd ats md pe neem 9 mmm 00 Spt weeny imam oe ‘same aera en ad nner me tm wat torso areaeasion ‘moan yore seu ipmund Ss as Semen Tee bate ws wae ed puny i ed 284 Kg ad eon ope 99°89 a“ uope m 340 omar wt 709 2am mya ea Pn op Pp Spam 2 my 2 sng aes Layee, me te po ‘sey plo patna por fs A 9 ‘um orgs aD enum om ume for open) (cua) neenentos pe nee serps enum muons ea condos ropeer gt ap pan 0 pg ‘pti pnp emir op moa gs ey "por emma sg ets 9 Saver oe ee opine pr omatop ay oamodog me ove par sop apn =) woes en om “aunt re uingo sco peu aan oa pe ‘resco Pre evan Ma pees er open seer seomdachioneadianSoon> dct sonar SHaoy SaaS ee Oe seer “ewst ape sp Ges psy i ve pai cn sacar 0 esp hwo a ase np oy "su gsr ge mea oe oxo 28 DON By ‘to ae wa pnp ora ofa eae Ree Po a soars pray nara oe oe mo SY AT er ‘aos pra yar alam 39 vay os spud mg gat ys a ad ssn et sey ens wearer per raya) sa ene sed ora mae Yr Pao fra en Sp aur w ser past wre bose amp Poe ego! NI NOE) F “Supe st gsoe qn pans ep So ddan oar -owonp #1 Ged ones ee 2a ou 90 wl ad np ne ‘ssonigons rata ego pes myeue dum mada Z “aoe a9. osama — tees a %o ws ro pet ssogmtoeny 4 Soa oe fs son fornia oe pea ‘sign ee For nes a ag Py ged iy pron ot Pap Pr soy ed ey mt es Sa ren pemay oe neni oo wv Bc ap (cma ere oe tno ‘FRALSWavO WEN GO DO08 DEY A Ea £2 ATEXT 00K 0 MEDGNAL CHEMISTRY 5 Tht sgn nt afar thar ht of alti te cont tevwenage py af the en ends on ntl pH ah may be ne hs, Selatan Chopin a ihr tin copy hn ola rb ae 2. 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