The document discusses prions, which are protein-only infectious agents that can assume two distinct structural forms and propagate information in a non-Mendelian fashion. Some evidence suggests that prions may play an adaptive role, as yeast prion proteins can facilitate the equal partitioning of proteins between daughter cells during cell division through the action of the molecular chaperone HSP104. This evidence implies that prions are at least partially adaptive.
The document discusses prions, which are protein-only infectious agents that can assume two distinct structural forms and propagate information in a non-Mendelian fashion. Some evidence suggests that prions may play an adaptive role, as yeast prion proteins can facilitate the equal partitioning of proteins between daughter cells during cell division through the action of the molecular chaperone HSP104. This evidence implies that prions are at least partially adaptive.
The document discusses prions, which are protein-only infectious agents that can assume two distinct structural forms and propagate information in a non-Mendelian fashion. Some evidence suggests that prions may play an adaptive role, as yeast prion proteins can facilitate the equal partitioning of proteins between daughter cells during cell division through the action of the molecular chaperone HSP104. This evidence implies that prions are at least partially adaptive.
Summary of Comments on Does the central dogma still
stand Page: 2 Page: 2 Author: frent Subject: Highlight Date: 14/05/2020, 1:53:19 AM
gate between daughter cells during cell division through
the action of the molecular chaperone HSP104 [45-48] strongly suggest that prions are at least partially adaptive Page: 2 Author: frent Subject: Highlight Date: 14/05/2020, 1:53:11 AM
The protein-only infectious agents and subsequently dis-
covered factors of epigenetic heredity received the name prions [15,16]. The prion proteins assume two distinct