Assignment

The Inherent Risks of Supply Chain Management in

Pharmaceutical Companies

Submitted to: Sharfuddin Ahmed Lisan

Lecturer

Submitted by: Tauhedul Islam

ID No: 18221003
Section: A
Department of Finance & Banking
Faculty of Business Studies

Submission Date: 28th September, 2019

Bangladesh University of Professionals

Abstract
Store network streamlining is presently a noteworthy research subject in procedure activities and
the executives. A lot of research has been attempted on office area and configuration, stock and
appropriation arranging, limit and generation arranging and point by point booking. Just a little
extent of this work straightforwardly addresses the issues looked in the pharmaceutical area.
Then again, this area is particularly prepared for and needing refined store network advancement
methods.
At the store network configuration arrange, a specific issue looked by this industry is the need to
offset future limit with foreseen requests even with the huge vulnerability that emerges out of
clinical preliminaries and contender movement. Proficient limit use plans and strong framework
speculation choices will be significant as administrative weights increment and edges are
dissolved. The capacity to find hubs of the inventory network in assessment safe houses and
streamline exchanging and move value structures brings about intriguing degrees of opportunity
with regards to the production network plan issue. Earlier even to scope quantification comes the
issue of pipeline and testing arranging, where the choice of items for advancement and the
planning of the improvement undertakings requires a cautious administration of hazard and
potential prizes.
At the activity organize, it is frequently hard to guarantee responsiveness. Most pharmaceutical
items include essential dynamic fixing (AI) creation (frequently multi-organize substance
combination or bioprocess) and optional (detailing) generation. Both of the stages are portrayed
by low assembling speeds and are hampered by the requirement for quality confirmation
exercises at a few points. It isn't bizarre for the general store network process duration to be 300
days. In this condition, store network debottlenecking and decoupling techniques together with
composed stock administration are significant for brisk reactions to changing business sector
patterns. A decent comprehension of what really drives the inventory network elements is
likewise required. Off again on again, sporadic elements are presented by business forms instead
of by outside interest, and might be wiped out by the re-structure of inner business procedures or
provider/client connections.
This paper will consider significant issues in store network structure and activity drawn from the
writing and from our community oriented research extends around there. The fundamental
highlights of the issues will be evaluated as will the writing to date.
Pharmaceutical organizations today face a various exhibit of dangers. Despite the fact that the
business is one of the world's most flourishing areas it isn't safe to the huge number of dangers
that undermine its capacity to contend. The pharmaceutical business is portrayed by an
exceptionally dangerous and protracted R&D procedure, extraordinary challenge for protected
innovation, stringent government guideline and incredible buyer weight. On one hand, Pharma
organizations face comparative dangers like those looked by different enterprises fire, blast,
apparatus breakdown, catastrophic events, business interference, obligation and so forth. Then
again, the colossal introduction to stock dangers, boundless falsifying of physician endorsed

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drugs, administrative deferrals for advertising and patent terminations. The Inherent Risks of
Supply Chain Management in Pharmaceutical Companies.

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 The Inherent Risks of Supply Chain Management in
Pharmaceutical Companies

Introduction

Pharmaceutical production network is a critical segment of the wellbeing framework in

providing meds, especially in nations where fundamental medications are given by neighborhood
pharmaceutical organizations. No past investigations exist evaluating dangers and interruptions
in pharmaceutical organizations while surveying the pharmaceutical store network. Any dangers
influencing the pharmaceutical organizations could disturb supply meds and wellbeing
framework productivity. The objective of this investigation was the hazard evaluation in
pharmaceutical industry in Iran thinking about procedure's need, peril and likelihood of dangers.

Handfield and Nicholas (2002) alludes to production network the executives as the incorporation
and the board of inventory network associations and the exercises through helpful authoritative
connections, compelling business procedures, and significant levels of data sharing to make high
performing worth frameworks that give part associations economical upper hand. On this, Lee et
al (2000) brought up that inventory network the board includes the progression of material, data,
and account in a system comprising of makers, wholesalers, providers and clients. Coordination
and incorporation of these streams and their connected exercises inside and crosswise over
organizations through improved inventory network connections to accomplish an economical
focused edge is basic for viable production network the board. The goal of inventory network the
executives along these lines, as indicated by Poole (1997), is to encourage the procedures
whereby essential stock is requested and changed in order to fulfill shopper inclinations
effectively. It is broadly realized that these procedures have been set apart by a proceeding with
move from the authentic utilization of open markets to new business coordination components
between vertically related market stages, for example, those among makers and processors, and
among processors and dispersion frameworks. This is valid most importantly for certain
assembling ventures, for example, vehicle creation, however is progressively clear in the
agrifood and pharmaceutical industry (Boehlje and Schrader, 1996).

The key issues in production network the executives today are the arrangement of the inventory
network and its proficient coordination with destinations of consumer loyalty and continuing
competency. This requires complex progression of data, materials, and over various utilitarian
territories both inside and among organizations. To accomplish these, organizations must
recognize, assess, rank, and deal with its store network dangers. The less fatty and progressively
incorporated inventory chains get the almost certain vulnerabilities, elements and mishaps in a
single connection influence different connections in the chain. Organizations' fixated on speed
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and cost, likewise causes supply chains to separate especially during the dispatch of new items
(Lee and Whang, 2000). Besides, Narayanan and Raman (2004) stated that planning activities
crosswise over firms is very troublesome on the grounds that, associations have various societies
and organizations can't depend on shared convictions or unwaveringness to spur their
accomplices. hazard the board is a topical issue in both practice and scholarly circles, no
exploration to date has been researched inside the all out Pharmaceutical store network as
appropriate to national social insurance drug store, (Mahender, 2005). Such research is
imperative since pharmaceuticals are basic to human services (PhRMA, 2004). As per Savage et
al (2006), specialists accept that pharmaceuticals are extraordinary and can't be dealt with like
different items. This is a result of the significant expense and long span of innovative work and
the repercussions of the item not being accessible, henceforth its criticality. Besides, there is no
disclaiming that Pharmaceutical items are a key contribution to social insurance treatment, so it
is basic that dangers connected to the sourcing, and entry of these items through to patients are
distinguished and oversaw (Breen, 2008). There is extensive proof that inability to oversee
inventory network chances adequately can have a noteworthy negative effect on associations
(Mitchell, 1995) which pharmaceutical industry isn't an exemption. Regardless of the potential
perils or dangers that an association may experience for its failure to appropriately deal with its
store network, it creates the impression that there is practically no impulse to appropriately
address the inner organization wasteful aspects in the pharmaceutical business not to mention the
wasteful aspects related with its outside chains.

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Literature Review

Regardless of the similitudes between inventory chains by and large, intrinsic contrasts that
recognize one industry production network from another additionally exist (Cooper et al., 1997).
As indicated by Mahender (2005) the stockpile chains of various businesses are disparate as they
address various needs. The pharmaceutical business is one of a kind from numerous points of
view and in an investigation made by Mahender (2005), it assumes a critical job in saving the
soundness of individuals, and not at all like different merchandise and enterprises, access to
human services administrations and items is frequently viewed as an individual right or all
inclusive qualification. This is bolstered by Ghana National Drug Policy Statement (2004) which
expressed that, a national medication arrangement frames the premise of government's obligation
to guarantee access of its natives to great quality medications at moderate costs, authorizing drug
guidelines, creating proficient principles, and advancing the sound utilization of medications.
Point of fact, items and administrations offered by the pharmaceutical business are of an
altogether different nature than those offered by most different ventures. Thusly, the hidden
elements of the business are atypical, which thusly achieve key and operational contrasts
between the pharmaceutical business production network and rest of the market inventory
network (PhRMA, 2004). Besides, Bradley and Weber (2004) hypothesized that the one of a
kind component of the pharmaceutical business is that it works two altogether different sorts of
inventory chains consistently. One inventory network bolsters the medication advancement stage
and the other one to sell a fruitful medication in the market. After a medication is propelled, a
totally extraordinary arrangement of destinations, drivers, and imperatives become
overwhelming. Presently, the center movements from nimbleness to high accessibility.
Therefore, there is a sensational move in the models and procedures utilized to help this period
of medication life cycle. An average pharmaceutical store network after a medication dispatch
recognized by Mahender (2005).

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From this stage, the unpredictability of the pharmaceutical inventory network results from the
contribution of numerous enormous free associations of exceptionally assorted nature. The key
partners in this production network incorporate different government offices, medical clinics,
centers, medicate makers, sedate wholesalers, drug store chains, retailers and research
associations. To compound issues further, a similar inventory network is in charge of the
circulation of physician recommended drugs, over the-counter (OTC) meds, generics, just as
biologics having diverse dealing with requirements and operational goals. Moreover, because of
the administrative idea of the business and various mergers and acquisitions to gain more
innovative work (R&D) aptitude, numerous pharmaceutical inventory systems have developed in
an uncontrolled manner as opposed to being gotten ready for ideal execution. On this Bradley
and Weber (2004) called attention to that a basic investigation will, in any case, uncover that, by
and large, the pharmaceutical business lays little accentuation on its inventory network
operational proficiency. Clearly, the targets and requirements dynamic in these two stages are

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altogether different requiring altogether different kinds of inventory network capacities. While
one inventory network is centered around encouraging a speedy finishing of the clinical
preliminaries to acquire a snappy endorsement, the point of the other store network is to meet
deals targets. Thus the drivers inspiring the production network configuration are speed and high
accessibility separately. Significant contemplations in the two cases incorporate safe
guardianship and uncommon taking care of prerequisites.

Pharmaceutical Supply Chain Risk

Mahender (2005) recommended that pharmaceutical store network hazard incorporate stockpile
deficiencies, invert coordinations, falsifying and crude material quality and accessibility. He
included that alongside security, the issue of deficiencies is additionally winding up basically
critical to the pharmaceutical business. The principle explanations behind deficiencies
incorporate administrative issues, item end, crude materials issues, fabricating issues, market
interest issues (Tyler and Mark, 2002). In Johnston (2004) see, the issues of deficiencies
emerging because of poor conjectures are fundamental to the effective activity of any production
network. As a rule, item deficiencies happen when startling interest for an item surpasses
generation ability. In the pharmaceutical business, poor figure exactness may result from, new
sign for a current item, abnormal illness flare-up , new item deals drastically surpassing desires,
wrong request determining strategies, Just-in-time (JIT) stock levels unfit to satisfy need spikes,
off name utilization by prescriber, domino impact from deficiency of a related item,
accumulating that misrepresents a potential lack, contract grants that produce enormous interest
moves in a brief timeframe (Tyler and Mark, 2002). Besides, Mahender (2005) attested that
stock administration additionally postures hazard in pharmaceutical production network. He said
that, meanwhile, the industry additionally had an acknowledgment that tossing more inventories
at the inventory network doesn't generally ensure that item accessibility targets are met. Be that
as it may, because of the profoundly sectioned nature of the market, stock administration in the
pharmaceutical business is inalienably troublesome. The multifaceted nature of stock
administration issue results from various stock approaches, volume changeability, regularity, and
neighborhood traits or occasions. It is additionally exacerbated by the strain to react rapidly. A
key prerequisite with moral and money related ramifications inciting over wary methodology for
extraordinary over-buffering on stock levels prompting pointless monetary waste. Once more,
because of various items, advertise blends, administrative limitations, and wellbeing concerns
present an intense test (Bradley and Weber, 2004). Furthermore, absence of information
uprightness makes it incredibly difficult for organizers to estimate and choose with certainty how
much stock of every thing ought to be kept anytime in the chain whenever. Another hazard
which is predominant in pharmaceutical store network is switch coordinations. Johnston (2004)
remarked that, overseeing item returns in the pharmaceutical business is substantially more than

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a basic coordinations challenge. Because of the touchy idea of medications and their potential
wellbeing and money related ramifications, the board of returned products is a genuine business
with legitimate consequences. Adding to this Mahender (2005) brought up that medication
review and medication lapse makes turn around coordinations to oversee. In clarifying he stated,
medications can be reviewed either because of a transitory issue with the item or a lasting
expulsion of the medication from the market because of medication security related issues. In
either case, sedate review is a noteworthy occasion that makes various issues, not the least of
which is the discolored notoriety of the organization. Mahender further contended that from tasks
stance as well, medicate review represents a noteworthy test as far as organizing the expulsion of
each unsold thing from each point in the production network. Subsequently, there are unexpected
moves in the volume of reviewed sedate in the system prompting limit gives a lack coming about
because of a transitory review or an abundance because of a changeless review - requiring quick
consideration. Remarking on medication termination, Johnston (2004) acknowledged that, it isn't
unexpected to anticipate that a little level of medications should stay unsold for quite a while and
in the end lapse he acknowledged that, it isn't unexpected to anticipate that a little level of
medications should stay unsold for quite a while and in the end lapse. An event that is
exacerbated by the business wide routine with regards to conveying significant levels of
completed merchandise stock. By and large, the terminated medications are expelled from the
client areas and pulverized by authorized organizations. Much of the time, the producer will
acknowledge the lapsed medication and discount a specific level of the cost back to the
purchaser as well. It is critical for the medication makers to painstakingly screen the amount and
example of medication lapse. An investigation of this information can be utilized to assess and
tune existing stock approaches and figures. The pharmaceutical organizations react to this
circumstance by keeping up huge supplies of such crude materials consistently. Since the
expense of crude material is immaterial contrasted with the open door cost of a lost deals, it is
prudent for the pharmaceutical organizations to hold this strategy.

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Conclusion

Hazard exists in for all intents and purposes each store network action whether it is perceived or
not. As Supply chain experts, we should be perceptive of the dangers that exist in-house and with
our providers.

The pharmaceutical inventory network used to be viewed as an apparatus to supply items to

showcase in a powerful manner, where the accentuation was on security of stock. Late changes
in the working condition imply that organizations are returning to the parts of their inventory
chains and distinguishing methods for separating extra advantages from them.

In this division specifically, the inventory network of intrigue isn't just the physical procedures of
change and appropriation of materials. Similarly significant is the "esteem chain" point of view
of dealing with the advancement and improvement forms through to limit and generation
arranging. There are as yet a few energizing exploration challenges in this worth chain, a large
number of which the procedure building/process frameworks designing network are very much
set to address.

After monetary and supply dangers which the greater part of them are outside issues, the top
hazard distinguished in pharmaceutical store network incorporate guideline issues. As one of the
most critical objectives of MOH is to help supply of medication, likewise not tending to those
dangers could conceivably damage sup-utilize chain. At that point proficient connection among
MOH and the pharmaceutical business could help both MOH and industry to survey and
alleviate administrative dangers.

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Reference
1. Anon (2002). Summary of the executive session on emergency preparedness and the
pharmaceutical supply chain. American Journal of Health-System Pharmacy, 59 (3),
247–253.
2. Applequist, G. E., Pekny, J. F., & Reklaitis, G. V. (2000). Risk and uncertainty in
managing chemical manufacturing supply chains. Computers of Chemical Engineering,
24, 2211–2222.
3. Ballance, R., Pogany, J. & Forstner, H. (1992). The world’s pharmaceutical industries.
London, UK: Edward Elgar [for UNIDO].
4. Barbosa-Povoa, A. P. F. D., & Pantelides, C. C. (1999). Design of multipurpose
production facilities: A RTN decomposition-based algorithm
5. Chaganti SR, Pharmaceutical marketing in India. Hyderabad: Pharma Med Press; 2007:
1-36.
6. Sagar GV, Pharmaceutical Industrial Management., Hyderabad: Pharma Med Press,
2005: 111-19.
7. Klemencic E. Management of the supply chain - Case of Danfoss district heating
business area [Master’s Thesis]. Ljubljana, Slovenia: University of Ljubljana; 2006.
8. Breen L. A preliminary examination of the risk in the pharmaceutical supply chain (PSC)
in the National Health Service (NHS) (UK). J. Serv. Sci. & Management, 2008.
9. Bindu SR, Ahuja BB. Vendor selection in supply chain using relative reliability risk
evaluation. J Theor Appl Inf Technol. 2010: 145-52.
10. Franco RJP. A methodology to capture, evaluate and reformulate a firm’s supplies chain
strategy as a conceptual system [Ph.D. Thesis]. Massachusetts, USA: Massachusetts
Institute of Technology; 2010.
11. Datamonitor. (August 2006). Pharmaceutical Outsourcing: New opportunities in a fully
Integrated Global Outsourcing Strategy. Datamonitor Pharmaceutical Report.
12. Vozobulova M. Performance measurement in pharmaceutical supply chain [Master’s
Thesis]. Tampere, Finland: Tampere University of Technology; 2011.
13. Yu, M., & Nagurney, A. (2013). Competitive food supply chain networks with
application to fresh produce. European Journal of Operational Research, 224(2), 273-282.
14. Mousazadeh, M., Torabi, S. A., & Zahiri, B. (2015). A robust possibilistic programming
approach for pharmaceutical supply chain network design. Computers & Chemical
Engineering, 82, 115-128.
15. Hafezalkotob, A. (2017). Competition, cooperation, and coopetition of green supply
chains under regulations on energy saving levels. Transportation Research Part E:
Logistics and Transportation Review, 97, 228-250.

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