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stion Asked 4th Jan, 2019

Stephen Azari Asambo
University of Ghana
is sample size calculated? And how will this data be analyzed ?
t to conduct a parallel trial study in which 3 care bundles will be
mented aimed to decrease neonatal sepsis.How is sample size
lated?

to be collected from patients will be clinical signs of sepsis and

samples for culture to determine the presence of infection.
outcome variable will be incidence of neonatal sepsis among
cipants.The study aims to evaluate the impact of the
vention on incidence of sepsis. What will be the best method to
ze this data

natal Sepsis Neonates Sepsis Data Collection Newborn Infant

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rs (1)

Habib Md Reazaul Karim 6th Jan, 2019

All India Institute of Medical Sciences,
Raipur

ample size calculation you will need what is the current

ence of sepsis and what amount of changes you are expecting
the intervention. You can go for both randomized and non-
omized design. In the sample size calculation, you have decide
much absolute precision (1-alfa) and power (1-beta) you want.
ly, absolute precision of 5% and power of 80% is acceptable
limit. If your trial is non-randomized, it is better to put a design
t. You can use online free statistical site www.openepi.com for

nalysis, it depends on the data. but from your objective, it

ars that you will require unpaired t-test, Fisher's exact/Chi-
re test. You can also calculate the sensitivity and specificity if
tervention is diagnostic and calculate the area under the curve
l interventions. For this you have to have one gold standard
e tests will be required if intervention is diagnostic only). At
nt statistical software also prompts what tests are appropriate
ded you enter the data type correctly.
 this helps you

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estions and discussions

n do I need to weight cases on SPSS?

stion 4 answers
d 5th Mar, 2019
eleted profile
planning to carry out a Spearman's Rank Correlation Test on
on the count of Species Richness and pH. Would I need to
ht the cases by Species Richness because it is a frequency
t? I have tried this but this increases the number of ranks and I
ot sure what I should do. Thanks in advance.

is the default reference category for outcome variable in

tic regression using spss?
stion 9 answers
d 9th Sep, 2018
i Azeez Al-Jumaili
conducting a logistic regression using SPSS and I am
ering what is the default reference value for the outcome
bles (1 vs 0 or 0 vs 1)?

ks

is the difference between univariate and multivariate logistic

ssion?
stion 9 answers
d 16th May, 2018
umuda Irgam
case control study be uni variate since the dependent /response
ble is either Y/N qualitative variable?When can multivariate
ic regression be used?

ran armitage trend test in spss?

stion 3 answers
d 8th Mar, 2018
dil Anwar Bhatti
o perform Cochran-Armitage (CA) trend test using spss?

we perform it on 2*2 as well as 2*3 contingency table?

doing case control study and have to select one best fit genetic
tance model for my study.

n should I use the dominant and recessive model of genetic

ciation study? Should I calculate the OR and CI if there is no
ciation?
stion 4 answers
d 15th Feb, 2018
epanwita Saha
,

working on the genetic association of the candidate SNP loci

my diseased phenotype. I have performed the chi square test
2x2 and 2x3 contingency table) to compare the genotype and
frequency between case and control groups. I did not find any
ficant association. Should I also use the dominant and
sive model? I don't know when should I use these models? Are
models applicable only when I can determine the risk allele by
quare analysis? Since I did not get any association as
ioned above, so is it required to calculate OR, RR , CI ?

e help.

ple size for a pilot study?

stion 27 answers
d 16th Sep, 2017
anesh Dangal
e need to use a specific method to determine sample size for a
study or any number of sample size can be taken for such a
survey or study?

he sample used for pilot testing be included in the final

rch sample?

are the factors considered for the sample size for a pilot
? Can I publish the results of a pilot study?
do I set up my variables in spss to compare dominant and non-
nant limbs of different velocities and major ankle motions?
stion 4 answers
d 10th Sep, 2017
acy Macfarlane

esent I am doing my dissertation which focuses on the

ence between runners and non-runners in relation to range of
on and peak torque of the motion plantar flexion and dorsi
n. However when setting out variables in SPSS one of the them
e labelled for e.g., Plantar flexion, velocity 60, then I continue
0 velocity then 360 and the same for Dorsi flexion. However
I compare the limbs should I enter this information in a new
ble i.e., limbs -dominant and non-dominant or add it to the label
emonstrated earlier on velocity and plantar flexion ?  Hope this
s sense         

nant, recessive and additive model in SPSS?

stion 4 answers
d 7th Aug, 2017
isbah Hussain
eryone, 

working on case control genetic data. I have data for SNP with
types AA, AG and GG. I want to check the effect of these
dual genotypes on the disease outcome, which in my case is
tes. Now I want to calculate unadjusted and adjusted (for age
ender) Odds ratio in SPSS. I calculated unadjusted Odds ratio
ing multinomial regression (is this suitable for my data?). But
ot know how to calculate Odds ratio after adjustment for age
eneder. 

ndly, How can I  apply dominant, recessive and co-dominant

el to check which fits more. 

ld be highly obliged if you provide me the flowchart of

mands like 

--> analyze--> regression--> .........

ks, 

ah

d t- test, minimal sample size to do it ?

stion 7 answers
d 31st May, 2017
avid Neves Silva
ple size to perform a paired t-test.
ublications

m levels of IL-6 in neonatal sepsis by Gram-positive and Gram-

tive bacteria
cle
001
Zhelezova · Iskra Altankova · S. Simeonova · [...] · E.
tova
terminate the IL-6 levels, CRP levels, leukocyte count, and
tive burst in neonates with Gram-positive and Gram-negative
s. Twenty-one neonates with positive blood cultures and
osis sepsis were included in the study. They were classificated
onates with Gram-positive infection (4 preterm and 6 term) and
Gram-negative inf...

y of Diagnostic Criteria of Hemophagocytic

hohistiocytosis in Neonatal and Pediatric Sepsis
cle
2020
ohsen Saleh Elalfy · Iman Ragab · Noureldin · [...] · S
ohammed
ground sepsis, a syndrome of physiologic, pathologic, and
emical abnormalities induced by infection, is a major public
h concern; There is overlap between clinical and laboratory
ia induced by sepsis and hemophagocytosis Aim of the Work to
pare HLH by its known criteria among patients with neonatal
s admitted to NICU an...

Can the Microbiologist Help in Diagnosing Neonatal Sepsis?

cle Full-text available
012
ichela Paolucci · Mariapaola Landini · Vittorio Sambri
atal sepsis can be classified into two subtypes depending upon
her the onset of symptoms is before 72 hours of life (early-
t neonatal sepsis-EONS) or later (late-onset neonatal sepsis-
S). These definitions have contributed greatly to diagnosis and
ment by identifying which microorganisms are likely to be
onsible for sepsis d...

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