Dwe Vavery pels Q bly ax Veug dlvey Syst Needed ° - Wig dases required) Solubil 4 issues > Wigs frequeuce of dees a pereutial byicity - Pct aot aAscom ert ; — solublike — Vydroplebic drugs. 6 Why fhe needs a * Coutrolled “coug clelivery, — contral wl ¢ i deliwery rate Sees 2. Site of releas€ Dg Hehic et sapoudt wis Toxic level. Therapeatic Reng AiniMam Offech vt timeRous Ff Deve Apumistraneal 1.2 Fareateral (Oral ) : Topica | G Percutaneous ) Nala Mucesal Rectal, Vaginal, or en) Pulrmonal (eresol /HyavoSel Ainlwlers ) L NV. iyecten eit u Types of Deve Delivery Oy steas « * Non. Degradable Systens (Peyyeoss , Metals ) © DitFusion ceutrolled eltne. . Cheically Covdvollen . . Bodgradable (hyirolysis, oreqmutc ) - Bok EResi ON, ~ SutFAce 2» PH ,temperahure Sfaulus CeSperse. .Image me wath involved ta designing Fas a Deng Del wery Syste ne A. a b : Hous Rest is drug reload ah . Uiko Surround i ig Ptud ? 1. @ Het love wi SIEM : re al = be \ > look at inside The Carrier (yen hawt alteatly dent Wis 4 ertten ) Gwen THe Ae oF CELEASE Ce SuRrAcE Content. how fer will drug. gs Slee eotside 0 Carvior - ~Consider Scenanrko SS, Miso a re. Geek Kamp 4 a aA Lloret So luhen wird. Teosker 6.3.1 Oy Ci Probl Starevent ¢ Cr (ti) U nstéadsy ere mug sud, ae “Drug eae in Canter [" a t Acsume That Cenen aay ‘te in polymer does not Van ducing. “he pobler . Me yo, el 2 Ar op last ahen ’ Bonceut cahion dw probably 260, bud For qonsraty , assume Cr (t= 20) = Cc will peuess This assumay 94: (Veins er an Suche 2 Conk nevi tan. Catt, d, O2CaLt 9) Ot Av oyere t40 a= Co at allys hs BC. rina h>o (y= e z@ Po (y= 0° ry fy Worwacee = I, : = M(t) 4) } tt +\< A O (tit) = t = t/t, nk yr thy, rk Se cet reactor i 00 | Qy-t to oe @® Ses Mm Co sot So OSS tee many : wr knetous 4 =0 4 at qt" = 6 6 =0 kg / tt, =Oqua Ctaun when mee Thin | Re ihopindoit variable Mus ee Dol hue uote. §—silubien utthed Simic aeity ComOwATION OF VOM ABLES ( Temesrcen Ge. COMBIME Tio fudereuderT WaeiAdLes wre fk SNCLS OBO VALIABLE. Clty) —» O= f(y) Where 1-Feig) IF THS LomtKS O1 Pee —> \ ove @ Two @c/te will become dhe SAME conDimMen . So look at “ Ea. Zz. es Qa re \aact Wut wo tm be mm ne nee Zz Nh) Same Power i) - (_# — , Cosnst Dat kL Peachat ik arly Saleced b ceuplete| aelichen tues at Shedd réndor te. Mee ries eek, wictcou Wgluet oni fool. Se Be ye Than w= 07 ict : . 3 CN oy ih n=\ he onstuct 4. Ne tug 4Bin) = nyt) —Co ; Go leo < PT isto EQN | 3st) 7 Phew Dt ae ye ulus 98 2p 28 ot AC o4* @ NEED 1D comert | Soom £4 wato Ul MusT USE CANA RULE Lis 26 | a sa % / dL tate] x iy (“ae 2 Gee)a Es - &() ji a tin = SS (ae @ heer Ceveert 4 Ww RHS. 0-68. 3 PRG Ale “HAG.4. YF aL Fel fee 3 | ‘i ths F 4 a Atte es] Ho ue (58) @ Ewary EQS ara +a © Ge no we «CODE.= Taraugl Rewva - Ree. 1O: tale a ay . lt de _ ke ( Ae er L ha AY? MueTieey I 2 de ; ite We z te 1 ae “pe ) ide Late ~2 (Fea, 1 dy 142 Les ne — anda - £8 Ay = Tie eR ‘ . dé | 2°? over | 0 = ae + Ue) ,New Coe Bc fic Sheuld Acduec fren B72 Eo ally's O=0 1a t>o yo 6-0 VAS SAME , yo 6=I VAS —>o Solve Ory wwtegnati ng tote L Z 2 OM) = ¢. | ea + Cc, Where C, (Cy ane Constants to be delrminat. BCL. q-0 © 2 | o a2 (=cC,\ € ay + Ce ae O ‘Ged GilEuan. Bolichin . 2 ple Li ecror funchon ef (1) Oe 4 - Hy).dm dimbusigns 2. . - -Co 4 reas | ={- ul (| oO whit S I waked De cute § dg nelogee .. - which u te feu 8 wx Yeo 3G ce Nog = Ay ay | _ “Aal6-C) % ,. 0 fe Oy x ahr (C-G) 26 Neal >> 0) sh PAE F oo COE SOB4, My — - Or lG-Co) i ‘he tara nie) ho - 82 "(C Ce) fics ®