Nama : Deni Saputra

Npm : A1D019050

 Function of cooperation between the plasma membrane, endoplasmic reticulum and

mitochondria
 Function Presence of microsomal and mitochondrial proteins and characteristics for
plasma membranes
 Formation of contractions
 Endoplasmic reticulum membrane markers
 Suggestions for inter-membrane compartments to be stable

 Fungsi Kerja sama yang antara membran plasma, retikulum endoplasma dan
mitokondria
 Fungsi Kehadiran protein mikrosomal dan mitokondria dan karakteristik untuk
membran plasma
 Pembentukan intraksi
 Penanda membran retikulum endoplasma
 Saran agar kompartemen antar-membran menjadi stabil

The International Journal of Biochemistry & Cell Biology

Proper cooperation between plasma membranes, endoplasmic reticulum and mitochondria

seems to be very important for the various cellular processes involved in Ca2 + signaling and
the maintenance of Ca2 + homeostasis.

The presence of microsomal and mitochondrial proteins along with characteristics for the
plasma membrane in the membrane membrane associated plasma membrane (PAM).

the formation of stable interactions between these three structures. We isolated the
membrane-related plasma membrane from Jurkat cells and found significant enrichment in
plasma membrane markers including plasma membranes Ca2 + -ATPase, Na +, K + -ATPase
and CD3 as well as sarco / endoplasmic reticulum

Ca2 + ATPase functions as a marker for endoplasmic reticulum membranes. In addition,

two proteins involved in store-operated Ca2 + entries, Orai1 located in the plasma membrane
and STIM1 endoplasmic reticulum protein were found in this fraction. Next, we observed a
rearrangement containing a protein complex STIM1 isolated from Jurkat cells undergoing
stimulation by thapsigargin.

In order that inter-membrane compartments which consist of plasma membranes and

endoplasmic reticulum, and be isolated as stable plasma membranes related to membrane
fractions, may be involved in store-operated Ca2 + entries, and the formation and rebuilding
have an important regulatory role in Ca2 + cellular homeostasis.