Blast Proteine Cu NR Acces

RID: U81HR50K01R
Job Title:NP_001073901:alpha-ketoglutarate-dependent...
Program: BLASTP
Database: nr All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
Query #1: alpha-ketoglutarate-dependent dioxygenase FTO isoform 3 [Homo sapiens]
Query ID: ref|NP_001073901.1 Length: 505
Sequences producing significant alignments:

Max Total
Query E Per.
Description Score Score
cover Value Ident Accession
alpha-ketoglutarate-dependent dioxygenase FTO isoform 3 [Homo... 1053 1053 100%
0.0 100.00 NP_001073901.1
alpha-ketoglutarate-dependent dioxygenase FTO isoform X3 [Pan... 1052 1052 100%
0.0 99.80 XP_024781684.1
unnamed protein product [Homo sapiens] 1052 1052 100%
0.0 99.80 BAG53322.1
alpha-ketoglutarate-dependent dioxygenase FTO isoform X2... 1050 1050 100%
0.0 99.60 XP_032013254.1
KIAA1752 protein [Homo sapiens] 1050 1050 100%
0.0 99.80 BAB21843.2
0.0 99.60 XP_510968.2
0.0 98.06 NP_001350820.1
0.0 97.86 XP_024781683.1
0.0 99.01 XP_003263101.1
0.0 96.01 NP_001350823.1
FTO isoform 3 [Pongo abelii] 1042 1042 100%
0.0 98.61 PNJ62567.1
0.0 97.67 XP_032013253.1
0.0 97.67 XP_009429081.1
alpha-ketoglutarate-dependent dioxygenase FTO [Pongo abelii] 1039 1039 100%
0.0 98.61 NP_001126250.1
PREDICTED: alpha-ketoglutarate-dependent dioxygenase FTO isofo... 1036 1036 100%
0.0 98.42 XP_005591989.1
0.0 98.61 XP_010356591.2
0.0 98.42 XP_023065721.2
0.0 98.42 XP_025225777.1
0.0 98.42 XP_033074312.1
FTO isoform 3 [Pan troglodytes] 1035 1035 98%
0.0 99.60 PNI63967.1
0.0 97.09 XP_030652817.1
0.0 99.00 PNI63969.1
0.0 98.22 XP_007991498.1
alpha-ketoglutarate-dependent dioxygenase FTO isoform X1 [Maca... 1033 1033 100%
0.0 98.02 XP_011760503.1
alpha-ketoglutarate-dependent dioxygenase FTO isoform X1 [Pong... 1033 1033 100%
0.0 96.70 XP_009248996.1
PREDICTED: alpha-ketoglutarate-dependent dioxygenase FTO... 1033 1033 100%
0.0 98.02 XP_011801988.1
0.0 97.82 XP_011827312.1
0.0 96.50 XP_025225776.1
0.0 98.59 PNJ62570.1
0.0 98.00 PNJ62571.1
0.0 96.83 XP_008984120.1
alpha-ketoglutarate-dependent dioxygenase FTO isoform X1 [Papi... 1021 1021 98%
0.0 98.00 XP_031514106.1
alpha-ketoglutarate-dependent dioxygenase FTO [Aotus nancymaae] 1021 1021 100%
0.0 97.03 XP_012303365.1
0.0 98.39 XP_014981634.1
0.0 98.39 XP_003916924.2
0.0 96.24 XP_003937323.1
alpha-ketoglutarate-dependent dioxygenase FTO [Sapajus apella] 1015 1015 100%
0.0 96.04 XP_032111506.1
0.0 97.80 XP_034796072.1
PREDICTED: alpha-ketoglutarate-dependent dioxygenase FTO [Cebu... 1014 1014 100%
0.0 95.64 XP_017385575.1
LOW QUALITY PROTEIN: alpha-ketoglutarate-dependent dioxygenase... 1014 1014 100%
0.0 96.24 XP_033090538.1
0.0 95.84 XP_017719562.1
0.0 91.23 XP_035138572.1
0.0 98.37 XP_011921553.1
0.0 98.37 XP_011921571.1
0.0 98.17 XP_007991499.1
0.0 96.60 XP_009248997.1
alpha-ketoglutarate-dependent dioxygenase FTO [Microcebus... 1004 1004 100%
0.0 94.85 XP_012628070.1
0.0 97.76 XP_011760506.1
0.0 94.26 XP_012508119.1
Chain A, Protein Fto [Homo sapiens] 996 996 94%
0.0 99.58 3LFM_A
Chain A, Alpha-ketoglutarate-dependent Dioxygenase Fto [Homo... 995 995 94%
0.0 99.58 4ZS2_A
0.0 97.93 XP_009194707.2
0.0 99.58 4QKN_A
0.0 99.16 5DAB_A
0.0 98.14 XP_028697425.1
0.0 98.34 XP_015298227.1
0.0 99.58 5F8P_A
Chain A, Alpha-ketoglutarate-dependent dioxygenase FTO [Homo... 989 989 93%
0.0 99.58 6AKW_A
0.0 94.85 NP_001350826.1
0.0 94.18 XP_012508120.1
0.0 92.28 XP_012662320.1
0.0 91.88 XP_015343973.1
alpha-ketoglutarate-dependent dioxygenase FTO [Marmota... 975 975 100%
0.0 91.68 XP_027794874.1
0.0 91.49 XP_026248055.1
alpha-ketoglutarate-dependent dioxygenase FTO [Tupaia chinensis] 972 972 100%
0.0 93.08 XP_006148441.1
alpha-ketoglutarate-dependent dioxygenase FTO [Oryctolagus... 971 971 100%
0.0 91.88 NP_001186297.1
alpha-ketoglutarate-dependent dioxygenase FTO [Ictidomys... 971 971 100%
0.0 91.29 XP_005318239.1
0.0 93.27 XP_025225781.1
0.0 99.57 5ZMD_A
0.0 91.09 XP_014683258.1
PREDICTED: alpha-ketoglutarate-dependent dioxygenase FTO [Equu... 966 966 100%
0.0 90.89 XP_008511378.1
alpha-ketoglutarate-dependent dioxygenase FTO isoform X1 [Vulp... 966 966 100%
0.0 91.29 XP_025867549.1
0.0 90.50 XP_036690105.1
alpha-ketoglutarate-dependent dioxygenase FTO isoform X1 [Cani... 966 966 100%
0.0 91.29 XP_025302887.1
0.0 91.29 XP_003998090.1
alpha-ketoglutarate-dependent dioxygenase FTO isoform X3 [Equu... 964 964 100%
0.0 90.69 XP_005608321.1
0.0 90.69 XP_006186034.1
0.0 91.09 XP_019311473.1
0.0 90.89 XP_006207900.1
0.0 91.09 XP_026900282.1
0.0 90.10 XP_007167659.1
0.0 90.69 XP_007096738.1
0.0 90.89 XP_027949643.1
0.0 90.89 XP_027474669.1
alpha-ketoglutarate-dependent dioxygenase FTO isoform X1 [Lynx... 956 956 100%
0.0 90.50 XP_030155469.1
0.0 90.69 XP_025708148.1
RecName: Full=Alpha-ketoglutarate-dependent dioxygenase FTO;... 954 954 99%
0.0 91.00 F1PLN3.3
0.0 90.10 XP_006732653.1
alpha-ketoglutarate-dependent dioxygenase FTO isoform X7 [Homo... 952 952 90%
0.0 99.34 XP_016879145.1
0.0 99.56 XP_016879146.1
alpha-ketoglutarate-dependent dioxygenase FTO [Neomonachus... 952 952 100%
0.0 90.10 XP_021560370.1
0.0 89.90 XP_035937580.1
FTo [Sus scrofa] 950 950 100%
0.0 89.50 ACT65741.1
0.0 100.00 XP_024306205.1
0.0 88.91 XP_004371639.1
fat mass and obesity associated protein [Sus scrofa] 949 949 100%
0.0 89.50 AEY68263.1
0.0 100.00 NP_001350917.1
0.0 99.12 PNI63980.1
0.0 89.90 XP_034881088.1
0.0 99.56 PNI63979.1
Alignments:
>alpha-ketoglutarate-dependent dioxygenase FTO isoform 3 [Homo sapiens]
Sequence ID: NP_001073901.1 Length: 505
>alpha-ketoglutarate-dependent dioxygenase FTO isoform X2 [Gorilla gorilla gorilla]
Sequence ID: XP_018868158.1 Length: 505 >RecName: Full=Alpha-ketoglutarate-
dependent dioxygenase FTO; AltName: Full=Fat mass and obesity-associated protein;
AltName: Full=U6 small nuclear RNA (2'-O-methyladenosine-N(6)-)-demethylase FTO;
AltName: Full=U6 small nuclear RNA N(6)-methyladenosine-demethylase FTO; AltName:
Full=mRNA (2'-O-methyladenosine-N(6)-)-demethylase FTO; Short=m6A(m)-demethylase
FTO; AltName: Full=mRNA N(6)-methyladenosine demethylase FTO; AltName: Full=tRNA
N1-methyl adenine demethylase FTO [Homo sapiens]
Sequence ID: Q9C0B1.3 Length: 505 >Fat mass and obesity associated, partial
[synthetic construct]
Sequence ID: AAI48443.1 Length: 505 >Fat mass and obesity associated [synthetic
construct]
Sequence ID: AAI53033.1 Length: 505 >hCG23453 [Homo sapiens]
Sequence ID: EAW82811.1 Length: 505
Range 1: 1 to 505
Score:1053 bits(2724), Expect:0.0,

Method:Compositional matrix adjust.,
Identities:505/505(100%), Positives:505/505(100%), Gaps:0/505(0%)
Query 1 MKRTPTAEEREREAKKLRLLEELEDTWLPYLTPKDDEFYQQWQLKYPKLILREASSVSEE 60
MKRTPTAEEREREAKKLRLLEELEDTWLPYLTPKDDEFYQQWQLKYPKLILREASSVSEE
Sbjct 1 MKRTPTAEEREREAKKLRLLEELEDTWLPYLTPKDDEFYQQWQLKYPKLILREASSVSEE 60
Query 61 LHKEVQEAFLTLHKHGCLFRDLVRIQGKDLLTPVSRILIGNPGCTYKYLNTRLFTVPWPV 120

LHKEVQEAFLTLHKHGCLFRDLVRIQGKDLLTPVSRILIGNPGCTYKYLNTRLFTVPWPV
Sbjct 61 LHKEVQEAFLTLHKHGCLFRDLVRIQGKDLLTPVSRILIGNPGCTYKYLNTRLFTVPWPV 120
Query 121 KGSNIKHTEAEIAAACETFLKLNDYLQIETIQALEELAAKEKANEDAVPLCMSADFPRVG 180

KGSNIKHTEAEIAAACETFLKLNDYLQIETIQALEELAAKEKANEDAVPLCMSADFPRVG
Sbjct 121 KGSNIKHTEAEIAAACETFLKLNDYLQIETIQALEELAAKEKANEDAVPLCMSADFPRVG 180
Query 181 MGSSYNGQDEVDIKSRAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLVDRS 240

MGSSYNGQDEVDIKSRAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLVDRS
Sbjct 181 MGSSYNGQDEVDIKSRAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLVDRS 240
Query 241 AVAVYSYSCEGPEEESEDDSHLEGRDPDIWHVGFKISWDIETPGLAIPLHQGDCYFMLDD 300

AVAVYSYSCEGPEEESEDDSHLEGRDPDIWHVGFKISWDIETPGLAIPLHQGDCYFMLDD
Sbjct 241 AVAVYSYSCEGPEEESEDDSHLEGRDPDIWHVGFKISWDIETPGLAIPLHQGDCYFMLDD 300
Query 301 LNATHQHCVLAGSQPRFSSTHRVAECSTGTLDYILQRCQLALQNVCDDVDNDDVSLKSFE 360

LNATHQHCVLAGSQPRFSSTHRVAECSTGTLDYILQRCQLALQNVCDDVDNDDVSLKSFE
Sbjct 301 LNATHQHCVLAGSQPRFSSTHRVAECSTGTLDYILQRCQLALQNVCDDVDNDDVSLKSFE 360
Query 361 PAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVTNAVLHE 420

PAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVTNAVLHE
Sbjct 361 PAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVTNAVLHE 420
Query 421 VKREGLPVEQRNEILTAILASLTARQNLRREWHARCQSRIARTLPADQKPECRPYWEKDD 480

VKREGLPVEQRNEILTAILASLTARQNLRREWHARCQSRIARTLPADQKPECRPYWEKDD
Sbjct 421 VKREGLPVEQRNEILTAILASLTARQNLRREWHARCQSRIARTLPADQKPECRPYWEKDD 480
Query 481 ASMPLPFDLTDIVSELRGQLLEAKP 505

ASMPLPFDLTDIVSELRGQLLEAKP
Sbjct 481 ASMPLPFDLTDIVSELRGQLLEAKP 505
>alpha-ketoglutarate-dependent dioxygenase FTO isoform X3 [Pan paniscus]

Sequence ID: XP_024781684.1 Length: 505
Range 1: 1 to 505







VKREGLP+EQRNEILTAILASLTARQNLRREWHARCQSRIARTLPADQKPECRPYWEKDD
Sbjct 421 VKREGLPMEQRNEILTAILASLTARQNLRREWHARCQSRIARTLPADQKPECRPYWEKDD 480

>unnamed protein product [Homo sapiens]

Sequence ID: BAG53322.1 Length: 505
Range 1: 1 to 505






PAVLKQGEEIHNEVEFEWLRQFWFQGNRYR+CTDWWCQPMAQLEALWKKMEGVTNAVLHE
Sbjct 361 PAVLKQGEEIHNEVEFEWLRQFWFQGNRYRRCTDWWCQPMAQLEALWKKMEGVTNAVLHE 420


>alpha-ketoglutarate-dependent dioxygenase FTO isoform X2 [Hylobates moloch]

Range 1: 48 to 552






LNATHQHCVLAGSQPRFSSTHRVAECSTGTLDYILQRCQLALQN+ DDVDNDDVSLKSFE
Sbjct 348 LNATHQHCVLAGSQPRFSSTHRVAECSTGTLDYILQRCQLALQNIRDDVDNDDVSLKSFE 407



>KIAA1752 protein [Homo sapiens]
Sequence ID: BAB21843.2 Length: 505
Range 1: 1 to 505






LNATHQHCVLAGSQP FSSTHRVAECSTGTLDYILQRCQLALQNVCDDVDNDDVSLKSFE
Sbjct 301 LNATHQHCVLAGSQPWFSSTHRVAECSTGTLDYILQRCQLALQNVCDDVDNDDVSLKSFE 360



>alpha-ketoglutarate-dependent dioxygenase FTO isoform X5 [Pan troglodytes]

>FTO isoform 4 [Pan troglodytes]
Sequence ID: PNI63968.1 Length: 505
Range 1: 1 to 505








VK EGLP+EQRNEILTAILASLTARQNLRREWHARCQSRIARTLPADQKPECRPYWEKDD
Sbjct 421 VKGEGLPMEQRNEILTAILASLTARQNLRREWHARCQSRIARTLPADQKPECRPYWEKDD 480


Range 1: 1 to 515




Query 241 AVAVYSYSCEG----------PEEESEDDSHLEGRDPDIWHVGFKISWDIETPGLAIPLH 290

AVAVYSYSCEG PEEESEDDSHLEGRDPDIWHVGFKISWDIETPGLAIPLH
Sbjct 241 AVAVYSYSCEGTVCSWKKQPCPEEESEDDSHLEGRDPDIWHVGFKISWDIETPGLAIPLH 300
Query 291 QGDCYFMLDDLNATHQHCVLAGSQPRFSSTHRVAECSTGTLDYILQRCQLALQNVCDDVD 350

QGDCYFMLDDLNATHQHCVLAGSQPRFSSTHRVAECSTGTLDYILQRCQLALQNVCDDVD
Sbjct 301 QGDCYFMLDDLNATHQHCVLAGSQPRFSSTHRVAECSTGTLDYILQRCQLALQNVCDDVD 360
Query 351 NDDVSLKSFEPAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKM 410

NDDVSLKSFEPAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKM
Sbjct 361 NDDVSLKSFEPAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKM 420
Query 411 EGVTNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHARCQSRIARTLPADQKP 470

EGVTNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHARCQSRIARTLPADQKP
Sbjct 421 EGVTNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHARCQSRIARTLPADQKP 480
Query 471 ECRPYWEKDDASMPLPFDLTDIVSELRGQLLEAKP 505

ECRPYWEKDDASMPLPFDLTDIVSELRGQLLEAKP
Sbjct 481 ECRPYWEKDDASMPLPFDLTDIVSELRGQLLEAKP 515

Range 1: 1 to 515








EGVTNAVLHEVKREGLP+EQRNEILTAILASLTARQNLRREWHARCQSRIARTLPADQKP
Sbjct 421 EGVTNAVLHEVKREGLPMEQRNEILTAILASLTARQNLRREWHARCQSRIARTLPADQKP 480

>alpha-ketoglutarate-dependent dioxygenase FTO isoform X2 [Nomascus leucogenys]

Range 1: 1 to 505






LNATHQHCVLAGSQPRFSSTHRVAECSTGTLDYILQRCQLALQN+ D+VDNDDVSLKSFE
Sbjct 301 LNATHQHCVLAGSQPRFSSTHRVAECSTGTLDYILQRCQLALQNIHDNVDNDDVSLKSFE 360


VKREGLPVEQRNEILTAILASLTAR NLRREWHARCQSRIARTLPADQKPECRPYWEKDD
Sbjct 421 VKREGLPVEQRNEILTAILASLTARHNLRREWHARCQSRIARTLPADQKPECRPYWEKDD 480

ASMPLPFDLTDIVSELRG LLEAKP
Sbjct 481 ASMPLPFDLTDIVSELRGHLLEAKP 505

Range 1: 1 to 526






Query 361 PAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGV------- 413

PAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGV
Sbjct 361 PAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVISVELYK 420
Query 414 --------------TNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHARCQSR 459

TNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHARCQSR
Sbjct 421 ELGLMSPRLIRHKATNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHARCQSR 480
Query 460 IARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRGQLLEAKP 505

IARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRGQLLEAKP
Sbjct 481 IARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRGQLLEAKP 526
>FTO isoform 3 [Pongo abelii]

Sequence ID: PNJ62567.1 Length: 505
Range 1: 1 to 505


LHKEVQEAFLT+HKHGCLFRDLVRIQGKDLLTPVSRILIGNPGCTYKYLNTRLFTVPWPV
Sbjct 61 LHKEVQEAFLTMHKHGCLFRDLVRIQGKDLLTPVSRILIGNPGCTYKYLNTRLFTVPWPV 120

KGSNIKHTEAEIAAACETFLKLNDYLQIETIQALEELAAKEKANED VPLCMSADFPRVG
Sbjct 121 KGSNIKHTEAEIAAACETFLKLNDYLQIETIQALEELAAKEKANEDTVPLCMSADFPRVG 180

MGSSYNGQDEVD+KSRAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLVDRS
Sbjct 181 MGSSYNGQDEVDVKSRAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLVDRS 240


LNATHQHCVLAGSQPRFSSTHRVAECSTGTLDYILQRCQLALQNV DDV+NDDVSLKSFE
Sbjct 301 LNATHQHCVLAGSQPRFSSTHRVAECSTGTLDYILQRCQLALQNVRDDVENDDVSLKSFE 360

PAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKME VTNAVLHE
Sbjct 361 PAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEAVTNAVLHE 420


SMPLPFDLTDIVSELRGQLLEAKP
Sbjct 481 VSMPLPFDLTDIVSELRGQLLEAKP 505

Range 1: 48 to 562





QGDCYFMLDDLNATHQHCVLAGSQPRFSSTHRVAECSTGTLDYILQRCQLALQN+ DDVD
Sbjct 348 QGDCYFMLDDLNATHQHCVLAGSQPRFSSTHRVAECSTGTLDYILQRCQLALQNIRDDVD 407




Range 1: 1 to 515








EGVTNAVLHEVK EGLP+EQRNEILTAILASLTARQNLRREWHARCQSRIARTLPADQKP
Sbjct 421 EGVTNAVLHEVKGEGLPMEQRNEILTAILASLTARQNLRREWHARCQSRIARTLPADQKP 480
>alpha-ketoglutarate-dependent dioxygenase FTO [Pongo abelii]

>RecName: Full=Alpha-ketoglutarate-dependent dioxygenase FTO; AltName: Full=Fat
mass and obesity-associated protein; AltName: Full=U6 small nuclear RNA (2'-O-
methyladenosine-N(6)-)-demethylase FTO; AltName: Full=U6 small nuclear RNA N(6)-
methyladenosine-demethylase FTO; AltName: Full=mRNA (2'-O-methyladenosine-N(6)-)-
demethylase FTO; Short=m6A(m)-demethylase FTO; AltName: Full=mRNA N(6)-
methyladenosine demethylase FTO; AltName: Full=tRNA N1-methyl adenine demethylase
FTO [Pongo abelii]
Sequence ID: Q5R7X0.1 Length: 505 >hypothetical protein [Pongo abelii]
Sequence ID: CAH92140.1 Length: 505
Range 1: 1 to 505






LNATHQHCVLAGSQPRFSSTHRVAECSTGTLDYILQRCQLA QNV DDV+NDDVSLKSFE
Sbjct 301 LNATHQHCVLAGSQPRFSSTHRVAECSTGTLDYILQRCQLAPQNVRDDVENDDVSLKSFE 360



>PREDICTED: alpha-ketoglutarate-dependent dioxygenase FTO isoform X2 [Macaca
fascicularis]
>PREDICTED: alpha-ketoglutarate-dependent dioxygenase FTO isoform X1 [Cercocebus
atys]
Range 1: 37 to 541



KGSNIK+ EAEIAAACETFLKLNDYLQIETIQALEELAAKEKANEDAVPLCMSADFPRVG
Sbjct 157 KGSNIKYPEAEIAAACETFLKLNDYLQIETIQALEELAAKEKANEDAVPLCMSADFPRVG 216

MGSSY+GQDEVDIKSRAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLVDRS
Sbjct 217 MGSSYDGQDEVDIKSRAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLVDRS 276

AVAVYSYSCEGPEEES+DDSH EGRDPDIWHVGFKISWDIETPGLAIPLHQGDCYFMLDD
Sbjct 277 AVAVYSYSCEGPEEESDDDSHFEGRDPDIWHVGFKISWDIETPGLAIPLHQGDCYFMLDD 336

LNATHQHCVLAGSQPRFSSTHRVAECSTGTLDYILQRCQLALQNV DDVDN DVSLKSFE
Sbjct 337 LNATHQHCVLAGSQPRFSSTHRVAECSTGTLDYILQRCQLALQNVRDDVDNGDVSLKSFE 396



>alpha-ketoglutarate-dependent dioxygenase FTO isoform X1 [Rhinopithecus roxellana]

Range 1: 37 to 541





AVAVYSYSCEGPEEESEDDSH EGRDPDIWHVGFKISWDIETPGLAIPLHQGDCYFMLDD
Sbjct 277 AVAVYSYSCEGPEEESEDDSHFEGRDPDIWHVGFKISWDIETPGLAIPLHQGDCYFMLDD 336




Sbjct 517 ISMPLPFDLTDIVSELRGQLLEAKP 541
>alpha-ketoglutarate-dependent dioxygenase FTO isoform X1 [Piliocolobus

tephrosceles]
Range 1: 37 to 541



MGSSY+G DEVDIKSRAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLVDRS
Sbjct 217 MGSSYDGHDEVDIKSRAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLVDRS 276





>alpha-ketoglutarate-dependent dioxygenase FTO isoform X3 [Theropithecus gelada]

>Alpha-ketoglutarate-dependent dioxygenase FTO [Macaca mulatta]
Sequence ID: EHH31662.1 Length: 505 >Alpha-ketoglutarate-dependent dioxygenase FTO
[Macaca fascicularis]
Sequence ID: EHH60385.1 Length: 505
Range 1: 1 to 505








>alpha-ketoglutarate-dependent dioxygenase FTO isoform X1 [Trachypithecus

francoisi]
Range 1: 37 to 541


LHKEVQEAFLTL KHGCLFRDLVRIQGKDLLTPVSRILIGNPGCTYKYLNTRLFTVPWPV
Sbjct 97 LHKEVQEAFLTLRKHGCLFRDLVRIQGKDLLTPVSRILIGNPGCTYKYLNTRLFTVPWPV 156







Range 1: 1 to 497








Query 481 ASMPLPFDLTDIVSELR 497

ASMPLPFDLTDIVSELR
Sbjct 481 ASMPLPFDLTDIVSELR 497

Range 1: 1 to 515






QGDCYFMLDDLNATHQHCVLAGSQPRFSSTHRVAECSTGTLDYILQRCQLALQN+ D+VD
Sbjct 301 QGDCYFMLDDLNATHQHCVLAGSQPRFSSTHRVAECSTGTLDYILQRCQLALQNIHDNVD 360


EGVTNAVLHEVKREGLPVEQRNEILTAILASLTAR NLRREWHARCQSRIARTLPADQKP
Sbjct 421 EGVTNAVLHEVKREGLPVEQRNEILTAILASLTARHNLRREWHARCQSRIARTLPADQKP 480

ECRPYWEKDDASMPLPFDLTDIVSELRG LLEAKP
Sbjct 481 ECRPYWEKDDASMPLPFDLTDIVSELRGHLLEAKP 515

Range 1: 1 to 500







Query 481 ASMPLPFDLTDIVSELRGQL 500

ASMPLPFDLTDIVSELR ++
Sbjct 481 ASMPLPFDLTDIVSELRDRV 500
>PREDICTED: alpha-ketoglutarate-dependent dioxygenase FTO isoform X1 [Chlorocebus

sabaeus]
Range 1: 37 to 541






PAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVTNAVL E
Sbjct 397 PAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVTNAVLRE 456


>alpha-ketoglutarate-dependent dioxygenase FTO isoform X1 [Macaca nemestrina]

Range 1: 37 to 541









SMPLPFDLTD+VSELRGQLLEAKP
Sbjct 517 VSMPLPFDLTDLVSELRGQLLEAKP 541
>alpha-ketoglutarate-dependent dioxygenase FTO isoform X1 [Pongo abelii]
Range 1: 1 to 515





Sbjct 241 AVAVYSYSCEGTVRSWKKQPCPEEESEDDSHLEGRDPDIWHVGFKISWDIETPGLAIPLH 300

QGDCYFMLDDLNATHQHCVLAGSQPRFSSTHRVAECSTGTLDYILQRCQLALQNV DDV+
Sbjct 301 QGDCYFMLDDLNATHQHCVLAGSQPRFSSTHRVAECSTGTLDYILQRCQLALQNVRDDVE 360


E VTNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHARCQSRIARTLPADQKP
Sbjct 421 EAVTNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHARCQSRIARTLPADQKP 480

ECRPYWEKDD SMPLPFDLTDIVSELRGQLLEAKP
Sbjct 481 ECRPYWEKDDVSMPLPFDLTDIVSELRGQLLEAKP 515
>PREDICTED: alpha-ketoglutarate-dependent dioxygenase FTO [Colobus angolensis

palliatus]
Range 1: 37 to 541




AVAVYSYSCEG EEESEDDSH EGRDPDIWHVGFKISWDIETPGLAIPLHQGDCYFMLDD
Sbjct 277 AVAVYSYSCEGSEEESEDDSHFEGRDPDIWHVGFKISWDIETPGLAIPLHQGDCYFMLDD 336

LNATHQHCVLAGSQPRFSSTHRVAECSTGTLDYILQRCQLALQN+ DDVDN DVSLKSFE
Sbjct 337 LNATHQHCVLAGSQPRFSSTHRVAECSTGTLDYILQRCQLALQNIRDDVDNGDVSLKSFE 396



>PREDICTED: alpha-ketoglutarate-dependent dioxygenase FTO [Mandrillus leucophaeus]

Range 1: 37 to 541






PAVLKQGEEI +VEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVTNAVLHE
Sbjct 397 PAVLKQGEEIXXQVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVTNAVLHE 456



Range 1: 1 to 515





AVAVYSYSCEG PEEES+DDSH EGRDPDIWHVGFKISWDIETPGLAIPLH
Sbjct 241 AVAVYSYSCEGMVCSAKKQPCPEEESDDDSHFEGRDPDIWHVGFKISWDIETPGLAIPLH 300

QGDCYFMLDDLNATHQHCVLAGSQPRFSSTHRVAECSTGTLDYILQRCQLALQNV DDVD
Sbjct 301 QGDCYFMLDDLNATHQHCVLAGSQPRFSSTHRVAECSTGTLDYILQRCQLALQNVRDDVD 360

N DVSLKSFEPAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKM
Sbjct 361 NGDVSLKSFEPAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKM 420



Range 1: 1 to 497









SMPLPFDLTDIVSELR
Sbjct 481 VSMPLPFDLTDIVSELR 497

Range 1: 1 to 500








SMPLPFDLTDIVSELR ++
Sbjct 481 VSMPLPFDLTDIVSELRDRV 500
>alpha-ketoglutarate-dependent dioxygenase FTO isoform X2 [Callithrix jacchus]

Range 1: 24 to 528

MKRTPTAEEREREAKKLRLLEELEDTWLPYLTPKDDEFYQQWQLKYPKLILREA SVSEE
Sbjct 24 MKRTPTAEEREREAKKLRLLEELEDTWLPYLTPKDDEFYQQWQLKYPKLILREAGSVSEE 83

KGS+IKHTEAEIA ACETFLKLNDYLQIETIQALEELAAKEKANEDAVPLCMSADFPRVG
Sbjct 144 KGSDIKHTEAEIATACETFLKLNDYLQIETIQALEELAAKEKANEDAVPLCMSADFPRVG 203

MGSSY+GQDEVD+KSRAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLVDRS
Sbjct 204 MGSSYDGQDEVDLKSRAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLVDRS 263

AVAVYSYSCEGPE ESEDDS+LEGRDPD WHVGFKISWDIETPGLAIPLHQGDCYFMLDD
Sbjct 264 AVAVYSYSCEGPEVESEDDSNLEGRDPDTWHVGFKISWDIETPGLAIPLHQGDCYFMLDD 323

LNATHQHCVLAGSQPRFSSTHRVAECSTGTLDYILQRCQLALQNV DDV + DV LKSFE
Sbjct 324 LNATHQHCVLAGSQPRFSSTHRVAECSTGTLDYILQRCQLALQNVRDDVASGDVCLKSFE 383

PAVLKQGEEIHNEVEFEWLRQFWFQGNRY+KCTDWWCQPMAQLE LWKKMEGVTNAVLHE
Sbjct 384 PAVLKQGEEIHNEVEFEWLRQFWFQGNRYKKCTDWWCQPMAQLEELWKKMEGVTNAVLHE 443


ASMPLPFDLTDIVSELRGQLLEA+P
Sbjct 504 ASMPLPFDLTDIVSELRGQLLEARP 528
>alpha-ketoglutarate-dependent dioxygenase FTO isoform X1 [Papio anubis]

Range 1: 37 to 535







Query 481 ASMPLPFDLTDIVSELRGQ 499

SMPLPFDLTDIVSELR +
Sbjct 517 VSMPLPFDLTDIVSELRAE 535
>alpha-ketoglutarate-dependent dioxygenase FTO [Aotus nancymaae]

Range 1: 1 to 505



KGSNIKHTEAEIA ACETFLKLNDYLQIETIQALEELAAKEKANEDAVPLCMSADFPRVG
Sbjct 121 KGSNIKHTEAEIATACETFLKLNDYLQIETIQALEELAAKEKANEDAVPLCMSADFPRVG 180



LNATHQHCVLAGSQPRFSSTHRVAECSTGTLDYILQRCQLALQNV DDV N DV LKSFE
Sbjct 301 LNATHQHCVLAGSQPRFSSTHRVAECSTGTLDYILQRCQLALQNVRDDVANGDVCLKSFE 360

PAVLKQGEEIHNEVEFEWLRQFWFQG+RY+KCTDWWCQPMAQLE LWKKMEGVTNAVLHE
Sbjct 361 PAVLKQGEEIHNEVEFEWLRQFWFQGSRYKKCTDWWCQPMAQLEELWKKMEGVTNAVLHE 420


>alpha-ketoglutarate-dependent dioxygenase FTO isoform X1 [Macaca mulatta]

Range 1: 37 to 534








Query 481 ASMPLPFDLTDIVSELRG 498

SMPLPFDLTDIVSELRG
Sbjct 517 VSMPLPFDLTDIVSELRG 534

fascicularis]
Range 1: 37 to 533









SMPLPFDLTDIVSELR
Sbjct 517 VSMPLPFDLTDIVSELR 533
>PREDICTED: alpha-ketoglutarate-dependent dioxygenase FTO [Saimiri boliviensis

boliviensis]
Range 1: 15 to 519



KGSNIKHTEAEIA ACETFLKLNDYLQIETIQALEELA KEKANEDAVPLCMSADFPRVG
Sbjct 135 KGSNIKHTEAEIATACETFLKLNDYLQIETIQALEELATKEKANEDAVPLCMSADFPRVG 194


AVAVYSYSCEGPE ES+DDS+LEGRDPD WHVGFKISWDIETPGLAIPLHQGDCYFMLDD
Sbjct 255 AVAVYSYSCEGPEVESDDDSNLEGRDPDTWHVGFKISWDIETPGLAIPLHQGDCYFMLDD 314


PAVLKQGEEIHNEVEFEWLRQFWFQGNRY+KCTDWWCQPMAQLE +WKKMEGVTNAVLHE
Sbjct 375 PAVLKQGEEIHNEVEFEWLRQFWFQGNRYKKCTDWWCQPMAQLEEMWKKMEGVTNAVLHE 434


ASM LPFDLTDIVSELRGQLLE +P
Sbjct 495 ASMHLPFDLTDIVSELRGQLLEGRP 519
>alpha-ketoglutarate-dependent dioxygenase FTO [Sapajus apella]

Range 1: 24 to 528

MKRT TAEEREREAKKLRLLEELEDTWLPYLTPKDDEFYQQWQLKYPKLILREA SVSEE
Sbjct 24 MKRTQTAEEREREAKKLRLLEELEDTWLPYLTPKDDEFYQQWQLKYPKLILREAGSVSEE 83


KGS+IK+TEAEIA ACETFLKLND+LQ+ETIQALEELAAKEKANEDAVPLCMSADFPRVG
Sbjct 144 KGSDIKYTEAEIATACETFLKLNDFLQVETIQALEELAAKEKANEDAVPLCMSADFPRVG 203







Range 1: 13 to 512

Query 16 KLRLLEELEDTWLPYLTPKDDEFYQQWQLKYPKLILREASSVSEELHKEVQEAFLTLHKH 75
KLRLLEELEDTWLPYLTPKDDEFYQQWQLKYPKLILREASSVSEELHKEVQEAFLTLHKH
Sbjct 13 KLRLLEELEDTWLPYLTPKDDEFYQQWQLKYPKLILREASSVSEELHKEVQEAFLTLHKH 72
Query 76 GCLFRDLVRIQGKDLLTPVSRILIGNPGCTYKYLNTRLFTVPWPVKGSNIKHTEAEIAAA 135

GCLFRDLVRIQGKDLLTPVSRILIGNPGCTYKYLNTRLFTVPWPVKGSNIKHTEAEIAAA
Sbjct 73 GCLFRDLVRIQGKDLLTPVSRILIGNPGCTYKYLNTRLFTVPWPVKGSNIKHTEAEIAAA 132
Query 136 CETFLKLNDYLQIETIQALEELAAKEKANEDAVPLCMSADFPRVGMGSSYNGQDEVDIKS 195

CETFLKLNDYLQIETIQALEELAAKEKANEDAVPLCMSADFPRVGMGSSYNGQDEVDIKS
Sbjct 133 CETFLKLNDYLQIETIQALEELAAKEKANEDAVPLCMSADFPRVGMGSSYNGQDEVDIKS 192
Query 196 RAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLVDRSAVAVYSYSCEG---- 251

RAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLVDRSAVAVYSYSCEG
Sbjct 193 RAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLVDRSAVAVYSYSCEGTVCS 252
Query 252 ------PEEESEDDSHLEGRDPDIWHVGFKISWDIETPGLAIPLHQGDCYFMLDDLNATH 305

PEEESEDDSHLEGRDPDIWHVGFKISWDIETPGLAIPLHQGDCYFMLDDLNATH
Sbjct 253 WKKQPCPEEESEDDSHLEGRDPDIWHVGFKISWDIETPGLAIPLHQGDCYFMLDDLNATH 312
Query 306 QHCVLAGSQPRFSSTHRVAECSTGTLDYILQRCQLALQNVCDDVDNDDVSLKSFEPAVLK 365

QHCVLAGSQPRFSSTHRVAECSTGTLDYILQRCQLALQNVCDDVDNDDVSLKSFEPAVLK
Sbjct 313 QHCVLAGSQPRFSSTHRVAECSTGTLDYILQRCQLALQNVCDDVDNDDVSLKSFEPAVLK 372
Query 366 QGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVTNAVLHEVKREG 425

QGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVTNAVLHEVKREG
Sbjct 373 QGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVTNAVLHEVKREG 432
Query 426 LPVEQRNEILTAILASLTARQNLRREWHARCQSRIARTLPADQKPECRPYWEKDDASMPL 485

LP+EQRNEILTAILASLTARQNLRREWHARCQSRIARTLPADQKPECRPYWEKDDASMPL
Sbjct 433 LPMEQRNEILTAILASLTARQNLRREWHARCQSRIARTLPADQKPECRPYWEKDDASMPL 492
Query 486 PFDLTDIVSELRGQLLEAKP 505

PFDLTDIVSELRGQLLEAKP
Sbjct 493 PFDLTDIVSELRGQLLEAKP 512
>PREDICTED: alpha-ketoglutarate-dependent dioxygenase FTO [Cebus imitator]
Range 1: 24 to 528

MKRT TAEEREREAKKLRLLEELEDTWLPYLTPKDDEFYQQWQLKYPKLILREA +VSEE
Sbjct 24 MKRTQTAEEREREAKKLRLLEELEDTWLPYLTPKDDEFYQQWQLKYPKLILREAGTVSEE 83





LNATHQHCVLAGSQPRFSSTHRVAECSTGTLDYILQRCQLALQNV DDV N D+ LKSFE
Sbjct 324 LNATHQHCVLAGSQPRFSSTHRVAECSTGTLDYILQRCQLALQNVRDDVANGDICLKSFE 383



ASMPLPFDLTD+VSELRGQLLEA+P
Sbjct 504 ASMPLPFDLTDVVSELRGQLLEARP 528
>LOW QUALITY PROTEIN: alpha-ketoglutarate-dependent dioxygenase FTO-like

[Trachypithecus francoisi]
Range 1: 1 to 505

MKRTPTAEERE +AKKLRLLEELEDTWLPYLTPKDDEFYQQWQLKYPKLILREASSVSEE
Sbjct 1 MKRTPTAEERECKAKKLRLLEELEDTWLPYLTPKDDEFYQQWQLKYPKLILREASSVSEE 60

LHKEVQEAFLTLHKHGCLF DLVRIQGKDLLTPVSRILIGN GCTYKYLNTRLFTVPWPV
Sbjct 61 LHKEVQEAFLTLHKHGCLFXDLVRIQGKDLLTPVSRILIGNTGCTYKYLNTRLFTVPWPV 120



AVAVYSYSCEGPEEESEDDSH E RDPDIWHVGFKISWDIETPGL IPLHQGDCYFMLDD
Sbjct 241 AVAVYSYSCEGPEEESEDDSHFESRDPDIWHVGFKISWDIETPGLTIPLHQGDCYFMLDD 300

LNATHQHC+LAGSQPRFSSTH+VAECSTGTLDYILQRCQLALQNV DDVDN DVSLKSFE
Sbjct 301 LNATHQHCILAGSQPRFSSTHQVAECSTGTLDYILQRCQLALQNVRDDVDNGDVSLKSFE 360

PAVLKQGEEIHNEVEFEWLR FWFQGNRYRKCTDWWCQP+A LEALWKKMEGVTNAVLHE
Sbjct 361 PAVLKQGEEIHNEVEFEWLRXFWFQGNRYRKCTDWWCQPVAHLEALWKKMEGVTNAVLHE 420

VKREGLPVEQRNEILTAILASLTARQNLRREWHARCQS+IARTLPADQKPECRPYWEKDD
Sbjct 421 VKREGLPVEQRNEILTAILASLTARQNLRREWHARCQSQIARTLPADQKPECRPYWEKDD 480

SMPLPFDLTDIVSELRGQLL+AKP
Sbjct 481 ISMPLPFDLTDIVSELRGQLLKAKP 505
>PREDICTED: alpha-ketoglutarate-dependent dioxygenase FTO [Rhinopithecus bieti]

Range 1: 1 to 505

MK TPTAEERER+AKKLRLLEELEDTWLPYLTPKDDEFYQQWQLKYPKLILREASSVSEE
Sbjct 1 MKCTPTAEERERKAKKLRLLEELEDTWLPYLTPKDDEFYQQWQLKYPKLILREASSVSEE 60


KGSN K+ EAEIAAACETFLKLNDYLQIETIQALEELAAKEKANEDAVPLCMSADFPRVG
Sbjct 121 KGSNTKYPEAEIAAACETFLKLNDYLQIETIQALEELAAKEKANEDAVPLCMSADFPRVG 180


AVAVYSYSCEGPEEESEDDSH E RDPDIWHVGFKISWDIETPG AIPLHQGDCYFMLDD
Sbjct 241 AVAVYSYSCEGPEEESEDDSHFESRDPDIWHVGFKISWDIETPGSAIPLHQGDCYFMLDD 300

L ATHQHCVLAGSQPRFSSTH+VAECSTGTLDYILQRCQLALQNV +DVDN D+SLK+FE
Sbjct 301 LYATHQHCVLAGSQPRFSSTHQVAECSTGTLDYILQRCQLALQNVRNDVDNGDISLKTFE 360

PAVLKQGEEIHNEVEFEWLRQFWFQGN YRKCTDWWCQP+AQLEALWKKMEGVTNAVLHE
Sbjct 361 PAVLKQGEEIHNEVEFEWLRQFWFQGNGYRKCTDWWCQPVAQLEALWKKMEGVTNAVLHE 420

VKREGLPVEQRNEILTAILASLTARQNLRREWHARCQS+IARTLPADQKPECRPYWEKDD
Sbjct 421 VKREGLPVEQRNEILTAILASLTARQNLRREWHARCQSQIARTLPADQKPECRPYWEKDD 480

Sbjct 481 ISMPLPFDLTDIVSELRGQLLKAKP 505

Range 1: 24 to 559




Query 241 AVAVYSYSCE-------------------------------GPEEESEDDSHLEGRDPDI 269

AVAVYSYSCE GPE ESEDDS+LEGRDPD
Sbjct 264 AVAVYSYSCEEMEFHHVVQAGPELLSSSNAPALASQSAGITGPEVESEDDSNLEGRDPDT 323
Query 270 WHVGFKISWDIETPGLAIPLHQGDCYFMLDDLNATHQHCVLAGSQPRFSSTHRVAECSTG 329

WHVGFKISWDIETPGLAIPLHQGDCYFMLDDLNATHQHCVLAGSQPRFSSTHRVAECSTG
Sbjct 324 WHVGFKISWDIETPGLAIPLHQGDCYFMLDDLNATHQHCVLAGSQPRFSSTHRVAECSTG 383
Query 330 TLDYILQRCQLALQNVCDDVDNDDVSLKSFEPAVLKQGEEIHNEVEFEWLRQFWFQGNRY 389

TLDYILQRCQLALQNV DDV + DV LKSFEPAVLKQGEEIHNEVEFEWLRQFWFQGNRY
Sbjct 384 TLDYILQRCQLALQNVRDDVASGDVCLKSFEPAVLKQGEEIHNEVEFEWLRQFWFQGNRY 443
Query 390 RKCTDWWCQPMAQLEALWKKMEGVTNAVLHEVKREGLPVEQRNEILTAILASLTARQNLR 449

+KCTDWWCQPMAQLE LWKKMEGVTNAVLHEVKREGLPVEQRNEILTAILASLTARQNLR
Sbjct 444 KKCTDWWCQPMAQLEELWKKMEGVTNAVLHEVKREGLPVEQRNEILTAILASLTARQNLR 503
Query 450 REWHARCQSRIARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRGQLLEAKP 505

REWHARCQSRIARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRGQLLEA+P
Sbjct 504 REWHARCQSRIARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRGQLLEARP 559

atys]
Range 1: 10 to 499


GCLFRDLVRIQGKDLLTPVSRILIGNPGCTYKYLNTRLFTVPWPVKGSNIK+ EAEIAAA
Sbjct 70 GCLFRDLVRIQGKDLLTPVSRILIGNPGCTYKYLNTRLFTVPWPVKGSNIKYPEAEIAAA 129

CETFLKLNDYLQIETIQALEELAAKEKANEDAVPLCMSADFPRVGMGSSY+GQDEVDIKS
Sbjct 130 CETFLKLNDYLQIETIQALEELAAKEKANEDAVPLCMSADFPRVGMGSSYDGQDEVDIKS 189
Query 196 RAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLVDRSAVAVYSYSCEGPEEE 255

RAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLVDRSAVAVYSYSCEGPEEE
Sbjct 190 RAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLVDRSAVAVYSYSCEGPEEE 249
Query 256 SEDDSHLEGRDPDIWHVGFKISWDIETPGLAIPLHQGDCYFMLDDLNATHQHCVLAGSQP 315

S+DDSH EGRDPDIWHVGFKISWDIETPGLAIPLHQGDCYFMLDDLNATHQHCVLAGSQP
Sbjct 250 SDDDSHFEGRDPDIWHVGFKISWDIETPGLAIPLHQGDCYFMLDDLNATHQHCVLAGSQP 309
Query 316 RFSSTHRVAECSTGTLDYILQRCQLALQNVCDDVDNDDVSLKSFEPAVLKQGEEIHNEVE 375

RFSSTHRVAECSTGTLDYILQRCQLALQNV DDVDN DVSLKSFEPAVLKQGEEIHNEVE
Sbjct 310 RFSSTHRVAECSTGTLDYILQRCQLALQNVRDDVDNGDVSLKSFEPAVLKQGEEIHNEVE 369
Query 376 FEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVTNAVLHEVKREGLPVEQRNEIL 435

FEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVTNAVLHEVKREGLPVEQRNEIL
Sbjct 370 FEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVTNAVLHEVKREGLPVEQRNEIL 429
Query 436 TAILASLTARQNLRREWHARCQSRIARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSE 495

TAILASLTARQNLRREWHARCQSRIARTLPADQKPECRPYWEKDD SMPLPFDLTDIVSE
Sbjct 430 TAILASLTARQNLRREWHARCQSRIARTLPADQKPECRPYWEKDDVSMPLPFDLTDIVSE 489
Query 496 LRGQLLEAKP 505

LRGQLLEAKP
Sbjct 490 LRGQLLEAKP 499
atys]
Range 1: 3 to 492








Query 496 LRGQLLEAKP 505

LRGQLLEAKP
Sbjct 483 LRGQLLEAKP 492

sabaeus]
Range 1: 6 to 496

Query 15 KKLRLLEELEDTWLPYLTPKDDEFYQQWQLKYPKLILREASSVSEELHKEVQEAFLTLHK 74
KKLRLLEELEDTWLPYLTPKDDEFYQQWQLKYPKLILREASSVSEELHKEVQEAFLTLHK
Sbjct 6 KKLRLLEELEDTWLPYLTPKDDEFYQQWQLKYPKLILREASSVSEELHKEVQEAFLTLHK 65
Query 75 HGCLFRDLVRIQGKDLLTPVSRILIGNPGCTYKYLNTRLFTVPWPVKGSNIKHTEAEIAA 134

HGCLFRDLVRIQGKDLLTPVSRILIGNPGCTYKYLNTRLFTVPWPVKGSNIK+ EAEIAA
Sbjct 66 HGCLFRDLVRIQGKDLLTPVSRILIGNPGCTYKYLNTRLFTVPWPVKGSNIKYPEAEIAA 125
Query 135 ACETFLKLNDYLQIETIQALEELAAKEKANEDAVPLCMSADFPRVGMGSSYNGQDEVDIK 194

ACETFLKLNDYLQIETIQALEELAAKEKANEDAVPLCMSADFPRVGMGSSY+GQDEVDIK
Sbjct 126 ACETFLKLNDYLQIETIQALEELAAKEKANEDAVPLCMSADFPRVGMGSSYDGQDEVDIK 185
Query 195 SRAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLVDRSAVAVYSYSCEGPEE 254

SRAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLVDRSAVAVYSYSCEGPEE
Sbjct 186 SRAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLVDRSAVAVYSYSCEGPEE 245
Query 255 ESEDDSHLEGRDPDIWHVGFKISWDIETPGLAIPLHQGDCYFMLDDLNATHQHCVLAGSQ 314

ES+DDSH EGRDPDIWHVGFKISWDIETPGLAIPLHQGDCYFMLDDLNATHQHCVLAGSQ
Sbjct 246 ESDDDSHFEGRDPDIWHVGFKISWDIETPGLAIPLHQGDCYFMLDDLNATHQHCVLAGSQ 305
Query 315 PRFSSTHRVAECSTGTLDYILQRCQLALQNVCDDVDNDDVSLKSFEPAVLKQGEEIHNEV 374

PRFSSTHRVAECSTGTLDYILQRCQLALQNV DDVDN DVSLKSFEPAVLKQGEEIHNEV
Sbjct 306 PRFSSTHRVAECSTGTLDYILQRCQLALQNVRDDVDNGDVSLKSFEPAVLKQGEEIHNEV 365
Query 375 EFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVTNAVLHEVKREGLPVEQRNEI 434

EFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVTNAVL EVKREGLPVEQRNEI
Sbjct 366 EFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVTNAVLREVKREGLPVEQRNEI 425
Query 435 LTAILASLTARQNLRREWHARCQSRIARTLPADQKPECRPYWEKDDASMPLPFDLTDIVS 494

LTAILASLTARQNLRREWHARCQSRIARTLPADQKPECRPYWEKDD SMPLPFDLTDIVS
Sbjct 426 LTAILASLTARQNLRREWHARCQSRIARTLPADQKPECRPYWEKDDVSMPLPFDLTDIVS 485
Query 495 ELRGQLLEAKP 505

ELRGQLLEAKP
Sbjct 486 ELRGQLLEAKP 496

Range 1: 13 to 512

KLRLLEELEDTWLPYLTPKDDEFYQQWQLKYPKLILREASSVSEELHKEVQEAFLT+HKH
Sbjct 13 KLRLLEELEDTWLPYLTPKDDEFYQQWQLKYPKLILREASSVSEELHKEVQEAFLTMHKH 72


CETFLKLNDYLQIETIQALEELAAKEKANED VPLCMSADFPRVGMGSSYNGQDEVD+KS
Sbjct 133 CETFLKLNDYLQIETIQALEELAAKEKANEDTVPLCMSADFPRVGMGSSYNGQDEVDVKS 192

Sbjct 193 RAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLVDRSAVAVYSYSCEGTVRS 252

QHCVLAGSQPRFSSTHRVAECSTGTLDYILQRCQLALQNV DDV+NDDVSLKSFEPAVLK
Sbjct 313 QHCVLAGSQPRFSSTHRVAECSTGTLDYILQRCQLALQNVRDDVENDDVSLKSFEPAVLK 372

QGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKME VTNAVLHEVKREG
Sbjct 373 QGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEAVTNAVLHEVKREG 432

LPVEQRNEILTAILASLTARQNLRREWHARCQSRIARTLPADQKPECRPYWEKDD SMPL
Sbjct 433 LPVEQRNEILTAILASLTARQNLRREWHARCQSRIARTLPADQKPECRPYWEKDDVSMPL 492

>alpha-ketoglutarate-dependent dioxygenase FTO [Microcebus murinus]

Range 1: 24 to 528

MKRTPTAEEREREAKKLRLLEELEDTWLPYLTPKDDEFYQQWQLKYPKLILREA SVSE+
Sbjct 24 MKRTPTAEEREREAKKLRLLEELEDTWLPYLTPKDDEFYQQWQLKYPKLILREAGSVSED 83

LHKEVQEAFLTLHKHGCLFRDLVRIQGKDLLTPVSRILIGNPG TYKYLNTRLFTVPWPV
Sbjct 84 LHKEVQEAFLTLHKHGCLFRDLVRIQGKDLLTPVSRILIGNPGYTYKYLNTRLFTVPWPV 143

KGSNIK+ EAEIAAAC+TFLKLNDYLQIETIQALEELA+KEKANEDAVP+CMSADFPR G
Sbjct 144 KGSNIKYGEAEIAAACQTFLKLNDYLQIETIQALEELASKEKANEDAVPVCMSADFPRFG 203

MGSS++GQDEVDIKSRAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLV+RS
Sbjct 204 MGSSHDGQDEVDIKSRAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLVERS 263

AVAVYSYSCEGPEEES+DDSHLEGRDPD WHVGFKISWDIETPGLAIPLHQGDCYFMLDD
Sbjct 264 AVAVYSYSCEGPEEESDDDSHLEGRDPDTWHVGFKISWDIETPGLAIPLHQGDCYFMLDD 323


PAVLKQGEEIHNEVEFEWLRQFWFQGNRY+KCTDWWCQPM QLE LWKKMEGVTNAVL E
Sbjct 384 PAVLKQGEEIHNEVEFEWLRQFWFQGNRYKKCTDWWCQPMTQLEELWKKMEGVTNAVLRE 443
VKREGLPVEQRNEILTAILASLT RQNLRREWHARCQ RIARTLP DQKPECRPYWEK+D
Sbjct 444 VKREGLPVEQRNEILTAILASLTTRQNLRREWHARCQCRIARTLPVDQKPECRPYWEKED 503

Sbjct 504 PSMPLPFDLTDVVSELRGQLLEAKP 528

Range 1: 16 to 506

+KLRLLEELEDTWLPYLTPKDDEFYQQWQLKYPKLILREASSVSEELHKEVQEAFLTLHK
Sbjct 16 QKLRLLEELEDTWLPYLTPKDDEFYQQWQLKYPKLILREASSVSEELHKEVQEAFLTLHK 75






EFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVTNAVLHEVKREGLP+EQRNEI
Sbjct 376 EFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVTNAVLHEVKREGLPMEQRNEI 435

LTAILASLTARQNLRREWHARCQSRIARTLPADQKPECRPYWEKDD SMPLPFDLTD+VS
Sbjct 436 LTAILASLTARQNLRREWHARCQSRIARTLPADQKPECRPYWEKDDVSMPLPFDLTDLVS 495

ELRGQLLEAKP
>PREDICTED: alpha-ketoglutarate-dependent dioxygenase FTO isoform X1 [Propithecus

coquereli]
Range 1: 1 to 505



KGSN+K+ EAEIAAAC+TFLKLNDYLQIETIQALEELA+KEKANED VP+C+S DFPRVG
Sbjct 121 KGSNVKYGEAEIAAACQTFLKLNDYLQIETIQALEELASKEKANEDDVPVCVSGDFPRVG 180

MGSSY+GQDEVDIKSRAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLV+RS
Sbjct 181 MGSSYDGQDEVDIKSRAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLVERS 240



PAVLKQGEEIHNEVEFEWLRQFWFQGNRY+KCTDWWCQPM QLE WKKMEGVTNAVL E
Sbjct 361 PAVLKQGEEIHNEVEFEWLRQFWFQGNRYKKCTDWWCQPMTQLEERWKKMEGVTNAVLRE 420


SMPLPFDLTDIVS+LRGQLLEAKP
Sbjct 481 PSMPLPFDLTDIVSDLRGQLLEAKP 505
>Chain A, Protein Fto [Homo sapiens]

Sequence ID: 3LFM_A Length: 495
>Chain A, ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE FTO [Homo sapiens]
Sequence ID: 4CXW_A Length: 495 >Chain A, ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE
FTO [Homo sapiens]
Sequence ID: 4CXX_A Length: 495 >Chain A, ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE
FTO [Homo sapiens]
Sequence ID: 4CXY_A Length: 495 >Chain A, Alpha-ketoglutarate-dependent dioxygenase
FTO [Homo sapiens]
Sequence ID: 4IDZ_A Length: 495 >Chain A, Alpha-ketoglutarate-dependent dioxygenase
FTO [Homo sapiens]
Sequence ID: 4IE0_A Length: 495 >Chain A, Alpha-ketoglutarate-dependent dioxygenase
FTO [Homo sapiens]
FTO [Homo sapiens]
FTO [Homo sapiens]
FTO [Homo sapiens]
Sequence ID: 4IE7_A Length: 495 >Chain A, Alpha-ketoglutarate-dependent Dioxygenase
Fto [Homo sapiens]
Sequence ID: 4QHO_A Length: 495
Range 1: 20 to 495

Query 30 YLTPKDDEFYQQWQLKYPKLILREASSVSEELHKEVQEAFLTLHKHGCLFRDLVRIQGKD 89
++TPKDDEFYQQWQLKYPKLILREASSVSEELHKEVQEAFLTLHKHGCLFRDLVRIQGKD
Sbjct 20 HMTPKDDEFYQQWQLKYPKLILREASSVSEELHKEVQEAFLTLHKHGCLFRDLVRIQGKD 79
Query 90 LLTPVSRILIGNPGCTYKYLNTRLFTVPWPVKGSNIKHTEAEIAAACETFLKLNDYLQIE 149

LLTPVSRILIGNPGCTYKYLNTRLFTVPWPVKGSNIKHTEAEIAAACETFLKLNDYLQIE
Sbjct 80 LLTPVSRILIGNPGCTYKYLNTRLFTVPWPVKGSNIKHTEAEIAAACETFLKLNDYLQIE 139
Query 150 TIQALEELAAKEKANEDAVPLCMSADFPRVGMGSSYNGQDEVDIKSRAAYNVTLLNFMDP 209

TIQALEELAAKEKANEDAVPLCMSADFPRVGMGSSYNGQDEVDIKSRAAYNVTLLNFMDP
Sbjct 140 TIQALEELAAKEKANEDAVPLCMSADFPRVGMGSSYNGQDEVDIKSRAAYNVTLLNFMDP 199
Query 210 QKMPYLKEEPYFGMGKMAVSWHHDENLVDRSAVAVYSYSCEGPEEESEDDSHLEGRDPDI 269

QKMPYLKEEPYFGMGKMAVSWHHDENLVDRSAVAVYSYSCEGPEEESEDDSHLEGRDPDI
Sbjct 200 QKMPYLKEEPYFGMGKMAVSWHHDENLVDRSAVAVYSYSCEGPEEESEDDSHLEGRDPDI 259


TLDYILQRCQLALQNVCDDVDNDDVSLKSFEPAVLKQGEEIHNEVEFEWLRQFWFQGNRY
Sbjct 320 TLDYILQRCQLALQNVCDDVDNDDVSLKSFEPAVLKQGEEIHNEVEFEWLRQFWFQGNRY 379

RKCTDWWCQPMAQLEALWKKMEGVTNAVLHEVKREGLPVEQRNEILTAILASLTARQNLR
Sbjct 380 RKCTDWWCQPMAQLEALWKKMEGVTNAVLHEVKREGLPVEQRNEILTAILASLTARQNLR 439

REWHARCQSRIARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRGQLLEAKP
Sbjct 440 REWHARCQSRIARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRGQLLEAKP 495
>Chain A, Alpha-ketoglutarate-dependent Dioxygenase Fto [Homo sapiens]

Sequence ID: 4ZS2_A Length: 478
Range 1: 3 to 478









Range 1: 2 to 485







Query 496 LRGQ 499

LR +
Sbjct 482 LRAE 485

Sequence ID: 4QKN_A Length: 476
Range 1: 3 to 476







Query 450 REWHARCQSRIARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRGQLLEA 503

REWHARCQSRIARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRGQLLEA
Sbjct 423 REWHARCQSRIARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRGQLLEA 476
Sequence ID: 5DAB_A Length: 479
Range 1: 4 to 479



TIQALEELAAKEKANEDAVPLCMSADFPRVGMGSSYNG EVDIKSRAAYNVTLLNFMDP
Sbjct 124 TIQALEELAAKEKANEDAVPLCMSADFPRVGMGSSYNGDVEVDIKSRAAYNVTLLNFMDP 183






Range 1: 16 to 499






EFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVTNAVLHEVKREGLPVEQRNEI
Sbjct 376 EFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVTNAVLHEVKREGLPVEQRNEI 435

LTAILASLTARQNLRREWHARCQSRIARTLPADQKPECRPYWEKDD SMPLPFDLTDIVS
Query 495 ELRG 498

ELRG
Sbjct 496 ELRG 499

fascicularis]
Range 1: 3 to 484







Query 496 LR 497

LR
Sbjct 483 LR 484

Sequence ID: 5F8P_A Length: 476
Range 1: 4 to 476







Query 450 REWHARCQSRIARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRGQLLE 502

REWHARCQSRIARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRGQLLE
Sbjct 424 REWHARCQSRIARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRGQLLE 476
>Chain A, Alpha-ketoglutarate-dependent dioxygenase FTO [Homo sapiens]
Sequence ID: 6AKW_A Length: 492
Range 1: 20 to 492







Query 450 REWHARCQSRIARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRGQLLE 502

REWHARCQSRIARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRGQLLE
Sbjct 440 REWHARCQSRIARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRGQLLE 492

Range 1: 1 to 479

MKRTPTAEEREREAK WQLKYPKLILREASSVSEE
Sbjct 1 MKRTPTAEEREREAK--------------------------WQLKYPKLILREASSVSEE 34








coquereli]
Range 1: 1 to 498






PAVLKQGEEIHNEVEFEWLRQFWFQGNRY+KCTDWWCQPM QLE WKKMEGVTNAVL E


SMPLPFDLTDIVS+LRG
Sbjct 481 PSMPLPFDLTDIVSDLRG 498
>alpha-ketoglutarate-dependent dioxygenase FTO isoform X2 [Otolemur garnettii]

Range 1: 1 to 504

MKRTPTAEEREREAKKLRLLEELEDTWLPYLTPKDDEFYQQWQLKYPKL+LREA SV E+
Sbjct 1 MKRTPTAEEREREAKKLRLLEELEDTWLPYLTPKDDEFYQQWQLKYPKLVLREAGSVPED 60

+HKE QEAFLTLHKHGCLFRDLVRIQGKDLLTPVSRILIGNPG TYKYLNTRLFTVPWPV
Sbjct 61 IHKEAQEAFLTLHKHGCLFRDLVRIQGKDLLTPVSRILIGNPGYTYKYLNTRLFTVPWPV 120

KGS++K+ EAEIAAAC+TFLKLNDYLQIET+QALEELA+KEK NEDAVPLC+S DFPRVG
Sbjct 121 KGSSVKYGEAEIAAACQTFLKLNDYLQIETVQALEELASKEKENEDAVPLCVSGDFPRVG 180

MGSSY+ QDEVD KSRAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLV+RS
Sbjct 181 MGSSYD-QDEVDFKSRAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLVERS 239

AVAVYSYSCEGPEEESEDDSHLEGRDPD WHVGFKISWDIETPGLAIPLHQGDCYFMLDD
Sbjct 240 AVAVYSYSCEGPEEESEDDSHLEGRDPDTWHVGFKISWDIETPGLAIPLHQGDCYFMLDD 299

LNATHQHCVLAGSQPRFSSTHRVAECS GTLDYILQRCQ+ALQNV DVDN DVSLKSFE
Sbjct 300 LNATHQHCVLAGSQPRFSSTHRVAECSAGTLDYILQRCQVALQNVRGDVDNGDVSLKSFE 359

PAVLKQGEEIHNEVEFEWLRQFWFQGNRY+KCTDWWCQPM QLE LWK+MEGVTNAVLHE
Sbjct 360 PAVLKQGEEIHNEVEFEWLRQFWFQGNRYKKCTDWWCQPMTQLEELWKRMEGVTNAVLHE 419

VKREGLPVEQRNEILTA+L LT RQNLRREWHARCQ RIARTLP DQKPECRPYWEKDD
Sbjct 420 VKREGLPVEQRNEILTAVLPLLTTRQNLRREWHARCQCRIARTLPVDQKPECRPYWEKDD 479
SMPLPFDLTDIVSELR QLLEAKP
Sbjct 480 PSMPLPFDLTDIVSELRSQLLEAKP 504
>PREDICTED: alpha-ketoglutarate-dependent dioxygenase FTO [Marmota marmota marmota]

Range 1: 1 to 504

MKRT TAEEREREAKKLRLLEELEDTWLPYLTPKDDEFYQQWQLKYPKLILRE+ SVSEE
Sbjct 1 MKRTQTAEEREREAKKLRLLEELEDTWLPYLTPKDDEFYQQWQLKYPKLILRESGSVSEE 60


KGSN+ +TEAEIAAAC+TFLKLNDYLQIETIQALEELA KEKANEDAVP+CM A+FPRVG
Sbjct 121 KGSNVNYTEAEIAAACQTFLKLNDYLQIETIQALEELAVKEKANEDAVPVCM-AEFPRVG 179

MGSSY+GQDEVD+KSRAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLV+RS
Sbjct 180 MGSSYDGQDEVDLKSRAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLVERS 239

AVAVYSYSCEG E+ES+DDS+ EGRDPD WHVGFKISWDIETPGLAIPLHQGDCYFMLDD
Sbjct 240 AVAVYSYSCEGSEDESDDDSNFEGRDPDTWHVGFKISWDIETPGLAIPLHQGDCYFMLDD 299

LNATHQHCVLAGSQPRFSSTHRVAECSTGTLDYILQR Q+ALQN+ DD++N DVSLKSFE
Sbjct 300 LNATHQHCVLAGSQPRFSSTHRVAECSTGTLDYILQRSQVALQNIRDDLENGDVSLKSFE 359

PA+LKQGEEIHNEVEFEWLRQFWFQG+RYRKCTDWWC+PM++LE LWKKME VTNAVL E
Sbjct 360 PAILKQGEEIHNEVEFEWLRQFWFQGSRYRKCTDWWCEPMSKLEGLWKKMESVTNAVLRE 419

VKREGLPVEQRNEILTAILA LT RQNLRREWHARCQ RIARTLP DQKP+CRPYWEKDD
Sbjct 420 VKREGLPVEQRNEILTAILAPLTTRQNLRREWHARCQCRIARTLPVDQKPDCRPYWEKDD 479

ASMPLPFDLTDIVSELR QLLEAKP
Sbjct 480 ASMPLPFDLTDIVSELRAQLLEAKP 504
>alpha-ketoglutarate-dependent dioxygenase FTO [Marmota flaviventris]

Range 1: 1 to 504

MKR+ TAEEREREAKKLRLLEELEDTWLPYLTPKDDEFYQQWQLKYPKLILRE+ SVSEE
Sbjct 1 MKRSQTAEEREREAKKLRLLEELEDTWLPYLTPKDDEFYQQWQLKYPKLILRESGSVSEE 60








>alpha-ketoglutarate-dependent dioxygenase FTO isoform X1 [Urocitellus parryii]

Range 1: 1 to 504


LHKEVQEAFLTLHKHGCLFRDLVRIQGKDLLTPVSRILIG+PGCTYKYLNTRLFTVPWPV
Sbjct 61 LHKEVQEAFLTLHKHGCLFRDLVRIQGKDLLTPVSRILIGDPGCTYKYLNTRLFTVPWPV 120

KGSN+ + EAEIAAAC+TFLKLNDYLQIETIQALEELA KEKANEDAVP+CM A+FPRVG
Sbjct 121 KGSNVNYAEAEIAAACQTFLKLNDYLQIETIQALEELAVKEKANEDAVPVCM-AEFPRVG 179
MGSSY+ QDEVD+KSRAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLVDRS
Sbjct 180 MGSSYDAQDEVDLKSRAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLVDRS 239





>alpha-ketoglutarate-dependent dioxygenase FTO [Tupaia chinensis]

Range 1: 1 to 506

MKRT TAEEREREAKKLRLLEELEDTWLPYLTPKDDEFYQQWQLKYPKLILREA S+SEE
Sbjct 1 MKRTQTAEEREREAKKLRLLEELEDTWLPYLTPKDDEFYQQWQLKYPKLILREAGSISEE 60

LHKEVQEAFLTLHKHGCLFRDLVRIQGKD+LTPVSRILIG+PGCTYKYLNTRLFTVPWPV
Sbjct 61 LHKEVQEAFLTLHKHGCLFRDLVRIQGKDVLTPVSRILIGDPGCTYKYLNTRLFTVPWPV 120

KGSNIK+TEAEIAAAC+TFLKLNDYLQ+ETIQALEELA+KEKANEDAVP+CMSADFPRVG
Sbjct 121 KGSNIKYTEAEIAAACQTFLKLNDYLQVETIQALEELASKEKANEDAVPVCMSADFPRVG 180

Query 241 AVAVYSYSCEGPEEESEDDS-HLEGRDPDIWHVGFKISWDIETPGLAIPLHQGDCYFMLD 299

AVAVY+YSC+ EE +D HLEGRDPDIWHVGFKISWDIETPGLAIPLHQGDCYFMLD
Sbjct 241 AVAVYNYSCDEDSEEESEDDSHLEGRDPDIWHVGFKISWDIETPGLAIPLHQGDCYFMLD 300
Query 300 DLNATHQHCVLAGSQPRFSSTHRVAECSTGTLDYILQRCQLALQNVCDDVDNDDVSLKSF 359

DLNATHQHCVLAGSQPRFSSTHRVAECSTGTLDYI QRCQLALQNV DDVDN D+SLK+F
Sbjct 301 DLNATHQHCVLAGSQPRFSSTHRVAECSTGTLDYISQRCQLALQNVRDDVDNGDISLKTF 360
Query 360 EPAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVTNAVLH 419

EPAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPM LE LWKKMEGVTNAVLH
Sbjct 361 EPAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMTHLEGLWKKMEGVTNAVLH 420
Query 420 EVKREGLPVEQRNEILTAILASLTARQNLRREWHARCQSRIARTLPADQKPECRPYWEKD 479

EVKREGLPVEQRNEILTAILA LT RQNLRREWHARCQSRIARTLP DQKPECRPYWEKD
Sbjct 421 EVKREGLPVEQRNEILTAILALLTTRQNLRREWHARCQSRIARTLPGDQKPECRPYWEKD 480
Query 480 DASMPLPFDLTDIVSELRGQLLEAKP 505

D SMPLPFDLTDIVSELRG LLEAKP
Sbjct 481 DPSMPLPFDLTDIVSELRGLLLEAKP 506
>alpha-ketoglutarate-dependent dioxygenase FTO [Oryctolagus cuniculus]

>fat mass and obesity associated protein [Oryctolagus cuniculus]
Sequence ID: ACJ53748.2 Length: 504
Range 1: 1 to 504



KGS I +TEAEI AAC+TFLKLNDYLQIETIQALEELA KEK NEDAVP+CM A+FPRVG
Sbjct 121 KGSTINYTEAEIGAACQTFLKLNDYLQIETIQALEELAVKEKENEDAVPVCM-AEFPRVG 179

Sbjct 180 MGSSYDGQDEVDMKSRAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLVDRS 239

AVAVY+YSCEGP++ES+DDS+LEGRDPDIWHVGFKISWDIETPGLAIPLHQGDCYFMLDD
Sbjct 240 AVAVYNYSCEGPDDESDDDSNLEGRDPDIWHVGFKISWDIETPGLAIPLHQGDCYFMLDD 299

LNATHQHCVLAGSQPRFSSTHRVAECS GTLDYILQRCQLALQNV DD D V+LKSFE
Sbjct 300 LNATHQHCVLAGSQPRFSSTHRVAECSMGTLDYILQRCQLALQNVRDDADGTAVTLKSFE 359

PAVLKQGEEIHNEVEFEWLRQ+WFQGNRY+KCTDWWC+PM QLE LWKKME VTNAVLHE
Sbjct 360 PAVLKQGEEIHNEVEFEWLRQYWFQGNRYKKCTDWWCEPMTQLEGLWKKMEDVTNAVLHE 419


SMPLPFDLT++VSELRG LLEAKP
Sbjct 480 PSMPLPFDLTELVSELRGLLLEAKP 504
>alpha-ketoglutarate-dependent dioxygenase FTO [Ictidomys tridecemlineatus]
Range 1: 1 to 504

MKRT TAEEREREAKKLRLLEELEDTWLPYLTPKDDEFYQQWQLKYPKLILRE+ SVS+E
Sbjct 1 MKRTQTAEEREREAKKLRLLEELEDTWLPYLTPKDDEFYQQWQLKYPKLILRESGSVSDE 60









Range 1: 1 to 479









Sequence ID: 5ZMD_A Length: 463
>Chain C, Alpha-ketoglutarate-dependent dioxygenase FTO [Homo sapiens]
Sequence ID: 5ZMD_C Length: 463 >Chain E, Alpha-ketoglutarate-dependent dioxygenase
FTO [Homo sapiens]
Sequence ID: 5ZMD_E Length: 463 >Chain G, Alpha-ketoglutarate-dependent dioxygenase
FTO [Homo sapiens]
Sequence ID: 5ZMD_G Length: 463
Range 1: 1 to 463

Query 37 EFYQQWQLKYPKLILREASSVSEELHKEVQEAFLTLHKHGCLFRDLVRIQGKDLLTPVSR 96
EFYQQWQLKYPKLILREASSVSEELHKEVQEAFLTLHKHGCLFRDLVRI+GKDLLTPVSR
Sbjct 1 EFYQQWQLKYPKLILREASSVSEELHKEVQEAFLTLHKHGCLFRDLVRIKGKDLLTPVSR 60
Query 97 ILIGNPGCTYKYLNTRLFTVPWPVKGSNIKHTEAEIAAACETFLKLNDYLQIETIQALEE 156

ILIGNPGCTYKYLNTRLFTVPWPVKGSNIKHTEAEIAAACETFLKLNDYLQIETIQALEE
Sbjct 61 ILIGNPGCTYKYLNTRLFTVPWPVKGSNIKHTEAEIAAACETFLKLNDYLQIETIQALEE 120
Query 157 LAAKEKANEDAVPLCMSADFPRVGMGSSYNGQDEVDIKSRAAYNVTLLNFMDPQKMPYLK 216

LAAKEKANEDAVPLCMSADFPRVGMGSSYNGQDEVDIKSRAAYNVTLLNFMDPQKMPYLK
Sbjct 121 LAAKEKANEDAVPLCMSADFPRVGMGSSYNGQDEVDIKSRAAYNVTLLNFMDPQKMPYLK 180
Query 217 EEPYFGMGKMAVSWHHDENLVDRSAVAVYSYSCEGPEEESEDDSHLEGRDPDIWHVGFKI 276

EEPYFGMGKMAVSWHHDENLVDRSAVAVYSYSCEGPEEESEDDSHLEGRDPDIWHVGFKI
Sbjct 181 EEPYFGMGKMAVSWHHDENLVDRSAVAVYSYSCEGPEEESEDDSHLEGRDPDIWHVGFKI 240
Query 277 SWDIETPGLAIPLHQGDCYFMLDDLNATHQHCVLAGSQPRFSSTHRVAECSTGTLDYILQ 336

SWDIETPGLAIPLHQGDCYFMLDDLNATH+HCVLAGSQPRFSSTHRVAECSTGTLDYILQ
Sbjct 241 SWDIETPGLAIPLHQGDCYFMLDDLNATHKHCVLAGSQPRFSSTHRVAECSTGTLDYILQ 300
Query 337 RCQLALQNVCDDVDNDDVSLKSFEPAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWW 396

RCQLALQNVCDDVDNDDVSLKSFEPAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWW
Sbjct 301 RCQLALQNVCDDVDNDDVSLKSFEPAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWW 360
Query 397 CQPMAQLEALWKKMEGVTNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHARC 456

CQPMAQLEALWKKMEGVTNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHARC
Sbjct 361 CQPMAQLEALWKKMEGVTNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHARC 420
Query 457 QSRIARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRGQ 499

QSRIARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRGQ
Sbjct 421 QSRIARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRGQ 463
>PREDICTED: alpha-ketoglutarate-dependent dioxygenase FTO isoform X1 [Equus asinus]

Range 1: 1 to 505

MKRTPTAEEREREAKKLRLLEELEDTWLPYLTPKDDEF QQWQLKYPKLILREASSV EE
Sbjct 1 MKRTPTAEEREREAKKLRLLEELEDTWLPYLTPKDDEFDQQWQLKYPKLILREASSVPEE 60

LHKEVQEAF LHKHGCLFRDLVRIQGKDLLTPVSRILIGNPGCTYKYLNTRLFTVPWPV
Sbjct 61 LHKEVQEAFFALHKHGCLFRDLVRIQGKDLLTPVSRILIGNPGCTYKYLNTRLFTVPWPV 120

KGSN K+ EAEIAAAC++FLKLNDYLQ ETIQALEELAAK+KAN DAVP+C+ DFPR+G
Sbjct 121 KGSNAKYNEAEIAAACQSFLKLNDYLQTETIQALEELAAKDKANIDAVPVCIGPDFPRLG 180

MGSS++GQDE+DIK+RAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLV+RS
Sbjct 181 MGSSFDGQDEMDIKNRAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLVERS 240

AVAVYSYSCEGPEEESEDD LEGRDPDIWHVGFKISWDIETPGLAIPLHQGDCYFMLDD
Sbjct 241 AVAVYSYSCEGPEEESEDDPQLEGRDPDIWHVGFKISWDIETPGLAIPLHQGDCYFMLDD 300

LNATHQHCVLAG PRFSSTHRVAECSTGTLDYI+Q CQLALQN+ D+ DN DVSLKS E
Sbjct 301 LNATHQHCVLAGLPPRFSSTHRVAECSTGTLDYIVQHCQLALQNIRDEADNGDVSLKSLE 360

PAVLKQGEEIHNEVEFEWLRQFWFQGNRY+KCTDWWCQPM QLE LWKKMEGVTNAVLHE
Sbjct 361 PAVLKQGEEIHNEVEFEWLRQFWFQGNRYKKCTDWWCQPMTQLEELWKKMEGVTNAVLHE 420
V+REG+PVEQRNEILTAILASLT RQNLRREWHARCQ RIARTLP DQKPECRPYWEKDD
Sbjct 421 VRREGVPVEQRNEILTAILASLTTRQNLRREWHARCQCRIARTLPVDQKPECRPYWEKDD 480

SMPLPFDLTDI+SELRG LLEAKP
Sbjct 481 PSMPLPFDLTDIISELRGLLLEAKP 505
>PREDICTED: alpha-ketoglutarate-dependent dioxygenase FTO [Equus przewalskii]

Range 1: 1 to 505

MKRTPTAEEREREAKKLRLLEELEDTWLPYLTPKDDEF QQWQLKYPKLILREA SV EE
Sbjct 1 MKRTPTAEEREREAKKLRLLEELEDTWLPYLTPKDDEFDQQWQLKYPKLILREAGSVPEE 60





LNATHQHCVLAG PRFSSTHRVAECSTGTLDYI+QRCQLALQN+ D+ DN DVSLKS E
Sbjct 301 LNATHQHCVLAGLPPRFSSTHRVAECSTGTLDYIVQRCQLALQNIRDETDNGDVSLKSLE 360

PAVLKQGEEIHNEVEFEWLRQFWFQGNRY+KCTDWWCQPM QLE LWKKME VTNAVLHE
Sbjct 361 PAVLKQGEEIHNEVEFEWLRQFWFQGNRYKKCTDWWCQPMTQLEELWKKMEAVTNAVLHE 420

V+REG+PVEQRNEILTAILASLT RQNLRREWHARCQ RIARTLP DQKPECRPYWEKDD
Sbjct 421 VRREGVPVEQRNEILTAILASLTTRQNLRREWHARCQCRIARTLPVDQKPECRPYWEKDD 480

>alpha-ketoglutarate-dependent dioxygenase FTO isoform X1 [Vulpes vulpes]

Range 1: 46 to 549

MKRTPTAEEREREAKKLRLLEELEDTWLPYLTPKDDEFYQQWQLKYPKLILREA SV E+
Sbjct 46 MKRTPTAEEREREAKKLRLLEELEDTWLPYLTPKDDEFYQQWQLKYPKLILREAGSVPED 105

LHKEVQEAFLTLHKHGC FRDLVRIQGKDLLTPVSRILIGNPGCTYKYLNTRLFTVPWPV
Sbjct 106 LHKEVQEAFLTLHKHGCFFRDLVRIQGKDLLTPVSRILIGNPGCTYKYLNTRLFTVPWPV 165

KG++ K+ EA IAAAC+TFLKLNDYLQIETIQALEELA KEK+N DAVP+C+ DFPRVG
Sbjct 166 KGASTKYDEAGIAAACQTFLKLNDYLQIETIQALEELACKEKSNIDAVPVCIGPDFPRVG 225

MGS ++GQDE+DIK+RAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLV+RS
Sbjct 226 MGS-FDGQDELDIKNRAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLVERS 284

AVAVYSYSCEGPEEESEDD LEGRDPD WHVGFKISWDIETPGLAIPLHQGDCYFMLDD
Sbjct 285 AVAVYSYSCEGPEEESEDDPQLEGRDPDTWHVGFKISWDIETPGLAIPLHQGDCYFMLDD 344

LNATHQHCVLAG PRFSSTHRVAECSTGTLDYILQRCQLALQNV D+ DN DVSLKSFE
Sbjct 345 LNATHQHCVLAGLPPRFSSTHRVAECSTGTLDYILQRCQLALQNVRDEADNGDVSLKSFE 404

P VLKQGEEIHNEVEFEWLRQ+WFQGNRYRKCTDWWCQPM QLE LWKKMEGVTNAVLHE
Sbjct 405 PVVLKQGEEIHNEVEFEWLRQYWFQGNRYRKCTDWWCQPMTQLEGLWKKMEGVTNAVLHE 464

V+REG+PVEQRNEILTAILA LT RQNLRREWHARCQSRIARTLP DQKPECRPYWEKDD
Sbjct 465 VRREGVPVEQRNEILTAILALLTTRQNLRREWHARCQSRIARTLPVDQKPECRPYWEKDD 524

SMPLPFDLTDIVSELRG LLEAKP
Sbjct 525 PSMPLPFDLTDIVSELRGLLLEAKP 549
>alpha-ketoglutarate-dependent dioxygenase FTO isoform X1 [Balaenoptera musculus]

Range 1: 15 to 519

MKRTPTAEEREREAKKLRLLEELEDTWLPYLTPKDDEFYQQWQLKYPKLILREA+SV EE
Sbjct 15 MKRTPTAEEREREAKKLRLLEELEDTWLPYLTPKDDEFYQQWQLKYPKLILREAASVPEE 74

KGS+ K+ EAE+AAAC+TFLKLNDYLQ+ETIQALEELAAKEKAN DAVP+C+ DFPRVG
Sbjct 135 KGSDAKYHEAEVAAACQTFLKLNDYLQVETIQALEELAAKEKANIDAVPVCIGPDFPRVG 194

MGSS++GQDE+D+K+RAAYNVTLLNFMDP KMPYLKEEPYFGMGKMAVSWHHDENLVDRS
Sbjct 195 MGSSFDGQDEIDMKNRAAYNVTLLNFMDPAKMPYLKEEPYFGMGKMAVSWHHDENLVDRS 254

AVAVYSYSCEGP+EESEDD LEGRDPDIWHVGFKISWDIETPGLAIPLHQGDCYFMLDD
Sbjct 255 AVAVYSYSCEGPDEESEDDPQLEGRDPDIWHVGFKISWDIETPGLAIPLHQGDCYFMLDD 314

LNATHQHCVLAG PRFSSTHRVAECSTGTLDYILQRCQ ALQN+ D+ DN +VSLKS E
Sbjct 315 LNATHQHCVLAGLPPRFSSTHRVAECSTGTLDYILQRCQSALQNIRDEADNGEVSLKSLE 374

P VLK GEEIHNEVEFEWLRQFWFQGNRY++CTDWWCQPM QLE LWKKMEG+TNAVL E
Sbjct 375 PVVLKHGEEIHNEVEFEWLRQFWFQGNRYKRCTDWWCQPMTQLEELWKKMEGLTNAVLRE 434

V+REG PVEQRNEILTAILA+LTARQNLRREWHARCQSRIARTLPADQKPECRPYWEKDD
Sbjct 435 VRREGTPVEQRNEILTAILATLTARQNLRREWHARCQSRIARTLPADQKPECRPYWEKDD 494

SMPLPFDLTDI+SELR LLEAKP
Sbjct 495 PSMPLPFDLTDIISELRSLLLEAKP 519
>alpha-ketoglutarate-dependent dioxygenase FTO isoform X1 [Canis lupus dingo]

>alpha-ketoglutarate-dependent dioxygenase FTO isoform X1 [Canis lupus familiaris]
Range 1: 46 to 549









>LOW QUALITY PROTEIN: alpha-ketoglutarate-dependent dioxygenase FTO [Felis catus]

Range 1: 1 to 504

MKRTPTAEEREREAKKLRLLEELEDTWLPYLTPKDDEFYQQWQLKYPKLILREA SV EE
Sbjct 1 MKRTPTAEEREREAKKLRLLEELEDTWLPYLTPKDDEFYQQWQLKYPKLILREAGSVPEE 60


KG++ ++ EAEIAAAC+TFL+LNDYLQIETIQALEELA KEK+N DAVP+C+ DFPRVG
Sbjct 121 KGASTRYEEAEIAAACQTFLRLNDYLQIETIQALEELACKEKSNIDAVPVCIGPDFPRVG 180

MGS ++GQDEVDIK+RAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLV+RS
Sbjct 181 MGS-FDGQDEVDIKNRAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLVERS 239


LNATHQHCVLAG PRFSSTHRVAECSTGTLDYILQRCQ+ALQNV D D DVSLKSFE
Sbjct 300 LNATHQHCVLAGLPPRFSSTHRVAECSTGTLDYILQRCQVALQNVRDGADGGDVSLKSFE 359

PAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKC+DWWCQPMAQLE LWKKMEGVTNAVL E
Sbjct 360 PAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCSDWWCQPMAQLEELWKKMEGVTNAVLRE 419

V+REG+PVEQRNEILTAILASLT RQNLRREWHARCQSRIARTLP DQKPECRPYWEKDD
Sbjct 420 VRREGVPVEQRNEILTAILASLTTRQNLRREWHARCQSRIARTLPVDQKPECRPYWEKDD 479
SMPLPFDLTD+VSELRG LLEAKP
Sbjct 480 PSMPLPFDLTDVVSELRGLLLEAKP 504
>alpha-ketoglutarate-dependent dioxygenase FTO isoform X3 [Equus caballus]

Range 1: 1 to 505







PAVLKQGEEIHNEVEFEWLRQFWFQGNRY+KCTDWWCQPM QLE LWKKME VTNAVLHE

V++EG+PVEQRNEILTAILASLT RQNLRREWHARCQ RIARTLP DQKPECRPYWEKDD
Sbjct 421 VRQEGVPVEQRNEILTAILASLTTRQNLRREWHARCQCRIARTLPVDQKPECRPYWEKDD 480

>alpha-ketoglutarate-dependent dioxygenase FTO isoform X1 [Camelus ferus]

>PREDICTED: alpha-ketoglutarate-dependent dioxygenase FTO [Camelus bactrianus]
Sequence ID: XP_010961939.1 Length: 505 >alpha-ketoglutarate-dependent dioxygenase
FTO isoform X1 [Camelus dromedarius]
Range 1: 1 to 505


LHKEVQEAFLTLHKHGCLFRDLVRIQGKD+LTPVSRILIGNPGCTYKYLNTRLFTVPWPV
Sbjct 61 LHKEVQEAFLTLHKHGCLFRDLVRIQGKDVLTPVSRILIGNPGCTYKYLNTRLFTVPWPV 120

KGS+ K++EAEIAAAC+TFLKLNDYLQIETIQALEELAA++KAN DAVP+C+ DFPRVG
Sbjct 121 KGSDAKYSEAEIAAACQTFLKLNDYLQIETIQALEELAARDKANIDAVPVCIGPDFPRVG 180

+GSS++GQDEVD K+RAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLV+RS
Sbjct 181 LGSSFDGQDEVDFKNRAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLVERS 240


LNATHQHCVLAG PRFSSTHRVAECSTGTLDYILQRCQLALQNV ++ DN + SLKS E
Sbjct 301 LNATHQHCVLAGLPPRFSSTHRVAECSTGTLDYILQRCQLALQNVRNEADNGEFSLKSLE 360

PAVLKQGEEIHNEVEFEWLRQFWFQGNRY+KCT+WWCQPM QLE LWKKMEGVTNAVLHE
Sbjct 361 PAVLKQGEEIHNEVEFEWLRQFWFQGNRYKKCTNWWCQPMTQLEELWKKMEGVTNAVLHE 420

V+REG PVEQRN+ILTAILA LT RQNLRREWHARCQ RIAR+LPADQKPECRPYWEKDD
Sbjct 421 VRREGAPVEQRNKILTAILAVLTTRQNLRREWHARCQCRIARSLPADQKPECRPYWEKDD 480

SMPLPF+LTDIVSELRG LLEAKP
Sbjct 481 PSMPLPFELTDIVSELRGLLLEAKP 505
>PREDICTED: alpha-ketoglutarate-dependent dioxygenase FTO [Panthera pardus]

Range 1: 1 to 504



MGS ++GQDE DIK+RAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLV+RS
Sbjct 181 MGS-FDGQDEADIKNRAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLVERS 239



PAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKC+DWWCQPMAQLE LWKKMEGVTNAVLHE
Sbjct 360 PAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCSDWWCQPMAQLEELWKKMEGVTNAVLHE 419

V+REG+PVEQRNEILTAILA LT+RQNLRREWHARCQSRIARTLP DQKPECRPYWEKDD
Sbjct 420 VRREGVPVEQRNEILTAILALLTSRQNLRREWHARCQSRIARTLPVDQKPECRPYWEKDD 479

>alpha-ketoglutarate-dependent dioxygenase FTO isoform X1 [Vicugna pacos]

Range 1: 1 to 505

MKRTPTAEEREREAKKLRLLEELEDTWLPYLTPKDDEFYQQWQLKYPKLILREA S+ EE
Sbjct 1 MKRTPTAEEREREAKKLRLLEELEDTWLPYLTPKDDEFYQQWQLKYPKLILREAGSIPEE 60



+GSS++GQDEVDIK+RAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLV+RS
Sbjct 181 LGSSFDGQDEVDIKNRAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLVERS 240

LNATHQHCVLAG PRFSSTHRVAECSTGTLDYILQRCQLALQNV ++ DN +VSLKS E
Sbjct 301 LNATHQHCVLAGLPPRFSSTHRVAECSTGTLDYILQRCQLALQNVRNEADNGEVSLKSLE 360

PAVLKQGEEIHNEVEFEWLRQFWFQGNRY+KCTDWW QPM QLE LWKKMEGVTNAVL E
Sbjct 361 PAVLKQGEEIHNEVEFEWLRQFWFQGNRYKKCTDWWWQPMTQLEELWKKMEGVTNAVLQE 420

V+REG PVEQRN+ILTAILA LT RQNLRREWHARCQ RIAR+LPADQKPECRPYWEKDD
Sbjct 421 VRREGAPVEQRNKILTAILAVLTTRQNLRREWHARCQCRIARSLPADQKPECRPYWEKDD 480

>alpha-ketoglutarate-dependent dioxygenase FTO isoform X4 [Acinonyx jubatus]

Range 1: 1 to 504






LNATHQHCVLAG PRFSSTHRVAECSTGTLDYILQRCQ+ALQNV D D D SLKSFE
Sbjct 300 LNATHQHCVLAGLPPRFSSTHRVAECSTGTLDYILQRCQVALQNVRDGADGGDASLKSFE 359

PAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKC+DWWCQPMAQLE LWKKMEGVTNAVL E


>alpha-ketoglutarate-dependent dioxygenase FTO isoform X1 [Balaenoptera

acutorostrata scammoni]
Range 1: 15 to 519


LHKEVQEAF TLHKHGCLFRDLVRIQGKDLLTPVSRILIGNPGCTYKYLNTRLFTVPWPV
Sbjct 75 LHKEVQEAFFTLHKHGCLFRDLVRIQGKDLLTPVSRILIGNPGCTYKYLNTRLFTVPWPV 134




LNATHQHCVLAG PRFSSTHRVAECSTGTLDYIL+RCQ ALQN+ D+ DN +VSLKS E
Sbjct 315 LNATHQHCVLAGLPPRFSSTHRVAECSTGTLDYILERCQSALQNIRDEADNGEVSLKSLE 374

P VLK GEEIHNEVEFEWLRQFWFQGNRY++CTDWWCQPM QLE LWKKMEG+TNAVL E

V+REG PVEQRNEILTAILA+LTARQNLRREWHARCQSRIARTLPADQKPECRPYWEKDD
Sbjct 435 VRREGTPVEQRNEILTAILATLTARQNLRREWHARCQSRIARTLPADQKPECRPYWEKDD 494

SMPLPFDLTDI+SELR LLEAKP
Sbjct 495 PSMPLPFDLTDIISELRSLLLEAKP 519
>PREDICTED: alpha-ketoglutarate-dependent dioxygenase FTO [Panthera tigris altaica]

Range 1: 1 to 504







P VLKQGEEIHNEVEFEWLRQFWFQGNRYRKC+DWWCQPMAQLE LWKKMEGVTNAVL E
Sbjct 360 PVVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCSDWWCQPMAQLEELWKKMEGVTNAVLRE 419

V+REG+PVEQRNEILTAILA LT+RQNLRREWHARCQSRIARTLP DQKPECRPYWEKDD
Sbjct 420 VRREGVPVEQRNEILTAILALLTSRQNLRREWHARCQSRIARTLPVDQKPECRPYWEKDD 479

>alpha-ketoglutarate-dependent dioxygenase FTO isoform X1 [Eumetopias jubatus]

Range 1: 46 to 549



KGS+ K+ EA IAAAC+TFLKLNDYLQ ET QALEELA KEKAN DAVP+C+ DFPRVG
Sbjct 166 KGSSPKYDEAGIAAACQTFLKLNDYLQTETSQALEELACKEKANIDAVPVCIGPDFPRVG 225
+GS ++GQDE+DIK+RAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLV+RS
Sbjct 226 LGS-FDGQDELDIKNRAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLVERS 284


LNATHQHCVLAG PRFSSTHRVAECSTGTLDYIL+RCQLALQNV ++VDN DVSLKSFE
Sbjct 345 LNATHQHCVLAGLPPRFSSTHRVAECSTGTLDYILERCQLALQNVRNEVDNGDVSLKSFE 404

PAVLKQGEEIHNEVEFEWLRQ+WFQGNRYRKCTDWWCQPM QLE LWKKMEGVTNAVLHE
Sbjct 405 PAVLKQGEEIHNEVEFEWLRQYWFQGNRYRKCTDWWCQPMTQLEGLWKKMEGVTNAVLHE 464


SMPLPFDLTDIVSELR LLE KP
Sbjct 525 PSMPLPFDLTDIVSELRSLLLEGKP 549
>alpha-ketoglutarate-dependent dioxygenase FTO isoform X1 [Zalophus californianus]

Range 1: 65 to 568









>alpha-ketoglutarate-dependent dioxygenase FTO isoform X1 [Lynx canadensis]

Range 1: 1 to 504


LHKEVQEAFL LHKHGC FRDLVRIQGKDLLTPVSRILIGNPGCTYKYLNTRLFTVPWPV
Sbjct 61 LHKEVQEAFLALHKHGCFFRDLVRIQGKDLLTPVSRILIGNPGCTYKYLNTRLFTVPWPV 120




LNATHQHCVLAG PRFSSTHRVAECS GTLDYILQRCQ+ALQNV D D DVSLKS E
Sbjct 300 LNATHQHCVLAGLPPRFSSTHRVAECSAGTLDYILQRCQVALQNVRDGADGGDVSLKSLE 359

P+VLKQGEEIHNEVEFEWLRQFWFQGNRYRKC+DWWCQPMAQLE LWKKMEGVTNAVL E
Sbjct 360 PSVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCSDWWCQPMAQLEELWKKMEGVTNAVLRE 419


SMPLPFDLTD VSELRG LLEAKP
Sbjct 480 PSMPLPFDLTDAVSELRGLLLEAKP 504
>alpha-ketoglutarate-dependent dioxygenase FTO isoform X2 [Callorhinus ursinus]
Range 1: 1 to 504

MKRTPTAEEREREAKKLRLLEELEDTWLPYLTPKDDEFYQQWQLKYPKL+LREA SV EE
Sbjct 1 MKRTPTAEEREREAKKLRLLEELEDTWLPYLTPKDDEFYQQWQLKYPKLVLREAGSVPEE 60


KGS K+ EA IAAAC+TFLKLNDYLQ ET QALEELA KEKAN DAVP+C+ DFPRVG
Sbjct 121 KGSTPKYDEAGIAAACQTFLKLNDYLQTETSQALEELACKEKANIDAVPVCIGPDFPRVG 180







FTO [Canis lupus familiaris]
Sequence ID: F1PLN3.3 Length: 506
Range 1: 1 to 499









SMPLPFDLTDIVSELRG+
Sbjct 480 PSMPLPFDLTDIVSELRGEF 499
>alpha-ketoglutarate-dependent dioxygenase FTO isoform X1 [Leptonychotes weddellii]

Range 1: 46 to 549

MKRTPTAEEREREAKKLRLLEELEDTWLPYLTPKDDEFYQQWQLKYPKLILREA SV E
Sbjct 46 MKRTPTAEEREREAKKLRLLEELEDTWLPYLTPKDDEFYQQWQLKYPKLILREAGSVPEA 105


KG++ K+ EA IAAAC+TFLKLNDYLQ ET QALEELA KEKAN DAVP+C+ DFPRVG
Sbjct 166 KGASPKYDEAGIAAACQTFLKLNDYLQTETSQALEELACKEKANIDAVPVCIGPDFPRVG 225
+G+ ++GQDE+DIK+RAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLV+RS
Sbjct 226 LGA-FDGQDELDIKNRAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLVERS 284




V+REG+PVEQR EILTAILA LT RQNLRREWHARCQSRIARTLP DQKPECRPYWEKDD
Sbjct 465 VRREGVPVEQRTEILTAILALLTTRQNLRREWHARCQSRIARTLPVDQKPECRPYWEKDD 524

>alpha-ketoglutarate-dependent dioxygenase FTO isoform X7 [Homo sapiens]

Range 1: 1 to 458







Query 421 VKREGLPVEQRNEILTAILASLTARQNLRREWHARCQS 458

VKREGLPVEQRNEILTAILASLTARQNLRREWHAR +
Sbjct 421 VKREGLPVEQRNEILTAILASLTARQNLRREWHARATT 458

Range 1: 1 to 457







Query 421 VKREGLPVEQRNEILTAILASLTARQNLRREWHARCQ 457

VKREGLPVEQRNEILTAILASLTARQNLRREWHAR +
Sbjct 421 VKREGLPVEQRNEILTAILASLTARQNLRREWHARVE 457
>alpha-ketoglutarate-dependent dioxygenase FTO [Neomonachus schauinslandi]

Range 1: 1 to 504



KG++ K+ EA+IAAAC+TFLKLNDYLQ ET QALEELA KEKAN DAVP+C+ DFPRVG
Sbjct 121 KGASPKYDEADIAAACQTFLKLNDYLQTETSQALEELACKEKANIDAVPVCIGPDFPRVG 180






>alpha-ketoglutarate-dependent dioxygenase FTO isoform X2 [Halichoerus grypus]

Range 1: 46 to 549


LHKEVQEAFLTLHKHGC FRDLVRIQGKDLLTPVSRILIGNPGCTYKYLNTRLFTVPWP+
Sbjct 106 LHKEVQEAFLTLHKHGCFFRDLVRIQGKDLLTPVSRILIGNPGCTYKYLNTRLFTVPWPL 165

KG++ ++ EA IAAAC+TFLKLNDYLQ ET QALEELA KEKAN DAVP+C+ DFPRVG
Sbjct 166 KGASPRYDEAGIAAACQTFLKLNDYLQTETSQALEELACKEKANIDAVPVCIGPDFPRVG 225






>FTo [Sus scrofa]

Sequence ID: ACT65741.1 Length: 505
>FTO [Sus scrofa]
Sequence ID: AIW04143.1 Length: 505 >fat mass and obesity-associated protein [Sus
scrofa]
Sequence ID: QNU12851.1 Length: 505 >FTO protein [Sus scrofa]
Sequence ID: CAP19644.1 Length: 505 >FTO protein [Sus scrofa]
Sequence ID: CAP91068.1 Length: 505
Range 1: 1 to 505

Sbjct 1 MKRTPTAEEREREAKKLRLLEELEDTWLPYLTPKDDEFYQQWQLKYPKLILREAGSVPEG 60

LHKEVQEAFL LHKHGCLFRDLVRIQGKDLLTPVSR+LIGNPGCTYKYLNTRLFTVPWPV
Sbjct 61 LHKEVQEAFLALHKHGCLFRDLVRIQGKDLLTPVSRLLIGNPGCTYKYLNTRLFTVPWPV 120

KGS+ K+ EAEI AAC+TFLKLNDYLQIETIQALEELAAKEKAN D VP+C+ DFPRVG
Sbjct 121 KGSDAKYNEAEIGAACQTFLKLNDYLQIETIQALEELAAKEKANIDTVPVCIGPDFPRVG 180

MGSS++G DEVD KSRAAYN+TLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLVDRS
Sbjct 181 MGSSFDGHDEVDRKSRAAYNLTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLVDRS 240

AVAVY+YSCEGPEEESEDD LEGRDPD+WHVGFKISWDIETPGLAIPLHQGDCYFMLDD
Sbjct 241 AVAVYNYSCEGPEEESEDDPQLEGRDPDVWHVGFKISWDIETPGLAIPLHQGDCYFMLDD 300
LNATHQHCVLAG PRFSSTHRVAECSTGTLDYILQRCQLALQNV D+ D+ +VSLKS E
Sbjct 301 LNATHQHCVLAGLPPRFSSTHRVAECSTGTLDYILQRCQLALQNVRDEADSGEVSLKSLE 360

PAVLKQGEEIHNEVEFEWLRQFWFQGNRY+KCTDWWCQPM QLE LWKKMEG T+AVL E
Sbjct 361 PAVLKQGEEIHNEVEFEWLRQFWFQGNRYKKCTDWWCQPMTQLEELWKKMEGATHAVLRE 420

V+REG PVEQ ++ILTAILA LT RQNLRREWHARCQSRIARTLP DQKPECRPYWEKDD
Sbjct 421 VRREGAPVEQSSDILTAILAVLTTRQNLRREWHARCQSRIARTLPVDQKPECRPYWEKDD 480

SMPLPFDLTD V+ELRG LLEAKP
Sbjct 481 PSMPLPFDLTDTVAELRGLLLEAKP 505

Range 1: 1 to 454







Query 421 VKREGLPVEQRNEILTAILASLTARQNLRREWHA 454

VKREGLPVEQRNEILTAILASLTARQNLRREWHA
Sbjct 421 VKREGLPVEQRNEILTAILASLTARQNLRREWHA 454
>alpha-ketoglutarate-dependent dioxygenase FTO isoform X1 [Trichechus manatus
latirostris]
Range 1: 1 to 505

MKRT TAEEREREAKKLRLLEELED WLPYLTPKDDEFYQQW LKYPKLILREA +V EE
Sbjct 1 MKRTQTAEEREREAKKLRLLEELEDAWLPYLTPKDDEFYQQWHLKYPKLILREADNVPEE 60


KGS IK+TE EI AAC+TFLKLNDYLQ ETIQALEEL +KEK++ DA+P+ ++ DFPR+G
Sbjct 121 KGSTIKYTEDEIGAACQTFLKLNDYLQTETIQALEELTSKEKSSGDALPVYIAPDFPRIG 180

MGSS++GQDE D+KSRAAYNVTLLNFMDPQKM YLKEEPYFGMGKMAVSWHHDENLV+RS
Sbjct 181 MGSSFDGQDEEDVKSRAAYNVTLLNFMDPQKMSYLKEEPYFGMGKMAVSWHHDENLVERS 240

AVAVY+YSCEGPEEESEDD LEGRDPD WHVGFKISWDIETPGLAIPLHQGDCYFMLDD
Sbjct 241 AVAVYNYSCEGPEEESEDDPDLEGRDPDTWHVGFKISWDIETPGLAIPLHQGDCYFMLDD 300

LNATHQHCVLAGSQPRFSSTHRVAECSTGTLDYILQRCQLALQN+ D+VD+ DVSLKS E
Sbjct 301 LNATHQHCVLAGSQPRFSSTHRVAECSTGTLDYILQRCQLALQNLRDEVDDGDVSLKSLE 360

PA+LKQGEEIHNEVEFEWLRQ+WFQGNRY+KCTDWWCQPM QLE LWKKMEGVTNAVL E
Sbjct 361 PAILKQGEEIHNEVEFEWLRQYWFQGNRYKKCTDWWCQPMTQLEGLWKKMEGVTNAVLRE 420

V++EGLPVEQRNEILTAILA LT RQNLRREWHARCQSRIARTL DQKPEC+PYWEKDD
Sbjct 421 VRKEGLPVEQRNEILTAILALLTTRQNLRREWHARCQSRIARTLSVDQKPECQPYWEKDD 480

Sbjct 481 PSMPLPFDLTDIVSELRGQLLQAKP 505
>fat mass and obesity associated protein [Sus scrofa]

Sequence ID: AEY68263.1 Length: 505
Range 1: 1 to 505

Sbjct 1 MKRTPTAEEREREAKKLRLLEELEDTWLPYLTPKDDEFYQQWQLKYPKLILREACSVPEG 60





PAVLKQGEEIHNEVEFEWLRQFWFQGNRY+KCTDWWCQPM QLE LWKKMEG T+AVL E

V+REG PVEQ ++ILTAILA LT RQNLRREWHARCQSRIARTLP DQKPECRPYWEKDD


Range 1: 1 to 455







Query 421 VKREGLPVEQRNEILTAILASLTARQNLRREWHAR 455

VKREGLPVEQRNEILTAILASLTARQNLRREWHAR
Sbjct 421 VKREGLPVEQRNEILTAILASLTARQNLRREWHAR 455

Range 1: 1 to 457







Query 421 VKREGLPVEQRNEILTAILASLTARQNLRREWHARCQ 457

VK EGLP+EQRNEILTAILASLTARQNLRREWHAR +
Sbjct 421 VKGEGLPMEQRNEILTAILASLTARQNLRREWHARVE 457
>alpha-ketoglutarate-dependent dioxygenase FTO isoform X1 [Mirounga leonina]
Range 1: 1 to 504







PAVLKQGEEIHNEVEFEWLRQ+WFQGNRYRKCTDWWCQPM QLE LWKKMEGVTNAVL E
Sbjct 360 PAVLKQGEEIHNEVEFEWLRQYWFQGNRYRKCTDWWCQPMTQLEGLWKKMEGVTNAVLRE 419



Range 1: 1 to 455







Query 421 VKREGLPVEQRNEILTAILASLTARQNLRREWHAR 455

VK EGLP+EQRNEILTAILASLTARQNLRREWHAR
Sbjct 421 VKGEGLPMEQRNEILTAILASLTARQNLRREWHAR 455


Max Total
Query E Per.
0.0 100.00 NP_001350820.1
0.0 99.81 XP_024781683.1
0.0 99.61 XP_032013253.1
0.0 99.61 XP_009429081.1
0.0 99.03 XP_030652817.1
0.0 98.45 XP_009248996.1
0.0 98.06 XP_025225776.1
0.0 98.06 NP_001073901.1
0.0 99.80 XP_034796072.1
0.0 97.86 XP_024781684.1
0.0 97.86 BAG53322.1
0.0 97.67 XP_032013254.1
0.0 97.67 XP_510968.2
0.0 97.86 BAB21843.2
0.0 97.09 XP_003263101.1
0.0 94.22 NP_001350823.1
0.0 96.70 PNJ62567.1
0.0 98.40 XP_009248997.1
0.0 96.70 NP_001126250.1
0.0 96.70 XP_010356591.2
0.0 96.50 XP_025225777.1
0.0 96.50 XP_005591989.1
0.0 96.50 XP_023065721.2
0.0 96.50 XP_033074312.1
0.0 97.63 PNI63967.1
0.0 97.06 PNI63969.1
0.0 96.31 XP_007991498.1
0.0 96.12 XP_011760503.1
0.0 96.12 XP_011801988.1
0.0 95.92 XP_011827312.1
0.0 96.65 PNJ62570.1
0.0 96.08 PNJ62571.1
0.0 95.15 XP_012303365.1
0.0 96.07 XP_031514106.1
0.0 94.95 XP_008984120.1
0.0 96.46 XP_014981634.1
0.0 96.45 XP_003916924.2
0.0 94.37 XP_003937323.1
0.0 94.17 XP_032111506.1
0.0 93.79 XP_017385575.1
0.0 91.42 XP_035138572.1
0.0 94.37 XP_033090538.1
0.0 93.98 XP_017719562.1
0.0 96.40 XP_011921553.1
0.0 96.40 XP_011921571.1
0.0 96.21 XP_007991499.1
0.0 93.01 XP_012628070.1
0.0 95.81 XP_011760506.1
0.0 92.43 XP_012508119.1
0.0 97.53 3LFM_A
0.0 97.53 4ZS2_A
0.0 95.95 XP_009194707.2
0.0 97.52 4QKN_A
0.0 96.34 XP_015298227.1
0.0 97.12 5DAB_A
0.0 97.52 6AKW_A
0.0 96.15 XP_028697425.1
0.0 97.52 5F8P_A
0.0 93.01 NP_001350826.1
0.0 92.32 XP_012508120.1
0.0 99.36 XP_011521616.1
0.0 99.15 XP_024781685.1
0.0 99.57 XP_011521617.1
0.0 100.00 XP_016879143.1
0.0 100.00 XP_011521618.1
0.0 98.93 XP_016785340.1
0.0 90.10 XP_015343973.1
0.0 99.14 XP_016785341.1
0.0 90.49 XP_012662320.1
0.0 92.43 XP_006148441.1
0.0 89.90 XP_027794874.1
0.0 99.15 XP_016785337.2
0.0 89.71 XP_026248055.1
0.0 90.10 NP_001186297.1
0.0 89.51 XP_005318239.1
0.0 97.46 5ZMD_A
0.0 91.46 XP_025225781.1
0.0 98.49 XP_024088822.1
0.0 98.07 XP_024088823.1
0.0 89.32 XP_014683258.1
0.0 89.13 XP_008511378.1
0.0 89.51 XP_025302887.1
0.0 89.51 XP_025867549.1
0.0 88.74 XP_036690105.1
0.0 88.93 XP_005608321.1
0.0 89.51 XP_003998090.1
0.0 88.93 XP_006186034.1
0.0 89.32 XP_019311473.1
0.0 89.13 XP_006207900.1
0.0 88.35 XP_007167659.1
0.0 89.32 XP_026900282.1
0.0 89.13 XP_027474669.1
0.0 88.93 XP_007096738.1
0.0 89.13 XP_027949643.1
0.0 88.74 XP_030155469.1
0.0 88.93 XP_025708148.1
0.0 89.22 F1PLN3.3
0.0 88.35 XP_006732653.1
0.0 97.22 XP_016879145.1
0.0 88.35 XP_021560370.1
Alignments:
Range 1: 1 to 515




Query 241 AVAVYSYSCEGTVCSWKKQPCPEEESEDDSHLEGRDPDIWHVGFKISWDIETPGLAIPLH 300

AVAVYSYSCEGTVCSWKKQPCPEEESEDDSHLEGRDPDIWHVGFKISWDIETPGLAIPLH





Range 1: 1 to 515










Range 1: 48 to 562









Range 1: 1 to 515









Range 1: 1 to 515










Range 1: 1 to 515





AVAVYSYSCEGTV SWKKQPCPEEESEDDSHLEGRDPDIWHVGFKISWDIETPGLAIPLH





Range 1: 1 to 515





AVAVYSYSCEG VCS KKQPCPEEES+DDSH EGRDPDIWHVGFKISWDIETPGLAIPLH





construct]
Range 1: 1 to 505





Sbjct 241 AVAVYSYSCEG----------PEEESEDDSHLEGRDPDIWHVGFKISWDIETPGLAIPLH 290





Range 1: 13 to 512



Query 196 RAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLVDRSAVAVYSYSCEGTVCS 255
RAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLVDRSAVAVYSYSCEGTVCS
Query 256 WKKQPCPEEESEDDSHLEGRDPDIWHVGFKISWDIETPGLAIPLHQGDCYFMLDDLNATH 315

WKKQPCPEEESEDDSHLEGRDPDIWHVGFKISWDIETPGLAIPLHQGDCYFMLDDLNATH



LP+EQRNEILTAILASLTARQNLRREWHARCQSRIARTLPADQKPECRPYWEKDDASMPL
Sbjct 433 LPMEQRNEILTAILASLTARQNLRREWHARCQSRIARTLPADQKPECRPYWEKDDASMPL 492


Range 1: 1 to 505










Range 1: 1 to 505







NDDVSLKSFEPAVLKQGEEIHNEVEFEWLRQFWFQGNRYR+CTDWWCQPMAQLEALWKKM
Sbjct 351 NDDVSLKSFEPAVLKQGEEIHNEVEFEWLRQFWFQGNRYRRCTDWWCQPMAQLEALWKKM 410


Range 1: 48 to 552










Range 1: 1 to 505









Range 1: 1 to 505





QGDCYFMLDDLNATHQHCVLAGSQP FSSTHRVAECSTGTLDYILQRCQLALQNVCDDVD
Sbjct 291 QGDCYFMLDDLNATHQHCVLAGSQPWFSSTHRVAECSTGTLDYILQRCQLALQNVCDDVD 350




Range 1: 1 to 505










Range 1: 1 to 526







Query 421 EGV---------------------TNAVLHEVKREGLPVEQRNEILTAILASLTARQNLR 459

EGV TNAVLHEVKREGLPVEQRNEILTAILASLTARQNLR
Sbjct 411 EGVISVELYKELGLMSPRLIRHKATNAVLHEVKREGLPVEQRNEILTAILASLTARQNLR 470


Range 1: 1 to 505









Range 1: 13 to 512




RAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLVDRSAVAVYSYSCEGTV S

WKKQPCPEEESEDDSHLEGRDPDIWHVGFKISWDIETPGLAIPLHQGDCYFMLDDLNATH


QGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKME VTNAVLHEVKREG



FTO [Pongo abelii]
Range 1: 1 to 505






QGDCYFMLDDLNATHQHCVLAGSQPRFSSTHRVAECSTGTLDYILQRCQLA QNV DDV+
Sbjct 291 QGDCYFMLDDLNATHQHCVLAGSQPRFSSTHRVAECSTGTLDYILQRCQLAPQNVRDDVE 350




Range 1: 37 to 541





AVAVYSYSCEG PEEESEDDSH EGRDPDIWHVGFKISWDIETPGLAIPLH
Sbjct 277 AVAVYSYSCEG----------PEEESEDDSHFEGRDPDIWHVGFKISWDIETPGLAIPLH 326




Sbjct 507 ECRPYWEKDDISMPLPFDLTDIVSELRGQLLEAKP 541

Range 1: 1 to 505





Sbjct 241 AVAVYSYSCEG----------PEEESDDDSHFEGRDPDIWHVGFKISWDIETPGLAIPLH 290




fascicularis]
atys]
Range 1: 37 to 541










tephrosceles]
Range 1: 37 to 541










francoisi]
Range 1: 37 to 541










Range 1: 1 to 497








Query 481 ECRPYWEKDDASMPLPFDLTDIVSELR 507

ECRPYWEKDDASMPLPFDLTDIVSELR
Sbjct 471 ECRPYWEKDDASMPLPFDLTDIVSELR 497

Range 1: 1 to 500








Query 481 ECRPYWEKDDASMPLPFDLTDIVSELRGQL 510

ECRPYWEKDDASMPLPFDLTDIVSELR ++
Sbjct 471 ECRPYWEKDDASMPLPFDLTDIVSELRDRV 500
sabaeus]
Range 1: 37 to 541








EGVTNAVL EVKREGLPVEQRNEILTAILASLTARQNLRREWHARCQSRIARTLPADQKP
Sbjct 447 EGVTNAVLREVKREGLPVEQRNEILTAILASLTARQNLRREWHARCQSRIARTLPADQKP 506


Range 1: 37 to 541









ECRPYWEKDD SMPLPFDLTD+VSELRGQLLEAKP
Sbjct 507 ECRPYWEKDDVSMPLPFDLTDLVSELRGQLLEAKP 541

palliatus]
Range 1: 37 to 541





AVAVYSYSCEG+ EEESEDDSH EGRDPDIWHVGFKISWDIETPGLAIPLH
Sbjct 277 AVAVYSYSCEGS----------EEESEDDSHFEGRDPDIWHVGFKISWDIETPGLAIPLH 326





Range 1: 37 to 541







N DVSLKSFEPAVLKQGEEI +VEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKM
Sbjct 387 NGDVSLKSFEPAVLKQGEEIXXQVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKM 446



Range 1: 1 to 497









ECRPYWEKDD SMPLPFDLTDIVSELR
Sbjct 471 ECRPYWEKDDVSMPLPFDLTDIVSELR 497

Range 1: 1 to 500









ECRPYWEKDD SMPLPFDLTDIVSELR ++
Sbjct 471 ECRPYWEKDDVSMPLPFDLTDIVSELRDRV 500

Range 1: 1 to 505





AVAVYSYSCEG PE ESEDDS+LEGRDPD WHVGFKISWDIETPGLAIPLH
Sbjct 241 AVAVYSYSCEG----------PEVESEDDSNLEGRDPDTWHVGFKISWDIETPGLAIPLH 290

QGDCYFMLDDLNATHQHCVLAGSQPRFSSTHRVAECSTGTLDYILQRCQLALQNV DDV
Sbjct 291 QGDCYFMLDDLNATHQHCVLAGSQPRFSSTHRVAECSTGTLDYILQRCQLALQNVRDDVA 350

N DV LKSFEPAVLKQGEEIHNEVEFEWLRQFWFQG+RY+KCTDWWCQPMAQLE LWKKM
Sbjct 351 NGDVCLKSFEPAVLKQGEEIHNEVEFEWLRQFWFQGSRYKKCTDWWCQPMAQLEELWKKM 410


ECRPYWEKDDASMPLPFDLTDIVSELRGQLLEA+P
Sbjct 471 ECRPYWEKDDASMPLPFDLTDIVSELRGQLLEARP 505

Range 1: 37 to 535







Query 481 ECRPYWEKDDASMPLPFDLTDIVSELRGQ 509

ECRPYWEKDD SMPLPFDLTDIVSELR +
Sbjct 507 ECRPYWEKDDVSMPLPFDLTDIVSELRAE 535

Range 1: 24 to 528







+ DV LKSFEPAVLKQGEEIHNEVEFEWLRQFWFQGNRY+KCTDWWCQPMAQLE LWKKM
Sbjct 374 SGDVCLKSFEPAVLKQGEEIHNEVEFEWLRQFWFQGNRYKKCTDWWCQPMAQLEELWKKM 433



Range 1: 37 to 534








Query 481 ECRPYWEKDDASMPLPFDLTDIVSELRG 508

ECRPYWEKDD SMPLPFDLTDIVSELRG
Sbjct 507 ECRPYWEKDDVSMPLPFDLTDIVSELRG 534

fascicularis]
Range 1: 37 to 533









ECRPYWEKDD SMPLPFDLTDIVSELR
Sbjct 507 ECRPYWEKDDVSMPLPFDLTDIVSELR 533

boliviensis]
Range 1: 15 to 519





AVAVYSYSCEG PE ES+DDS+LEGRDPD WHVGFKISWDIETPGLAIPLH
Sbjct 255 AVAVYSYSCEG----------PEVESDDDSNLEGRDPDTWHVGFKISWDIETPGLAIPLH 304


N DV LKSFEPAVLKQGEEIHNEVEFEWLRQFWFQGNRY+KCTDWWCQPMAQLE +WKKM
Sbjct 365 NGDVCLKSFEPAVLKQGEEIHNEVEFEWLRQFWFQGNRYKKCTDWWCQPMAQLEEMWKKM 424


ECRPYWEKDDASM LPFDLTDIVSELRGQLLE +P
Sbjct 485 ECRPYWEKDDASMHLPFDLTDIVSELRGQLLEGRP 519

Range 1: 24 to 528






N DV LKSFEPAVLKQGEEIHNEVEFEWLRQFWFQGNRY+KCTDWWCQPMAQLE LWKKM
Sbjct 374 NGDVCLKSFEPAVLKQGEEIHNEVEFEWLRQFWFQGNRYKKCTDWWCQPMAQLEELWKKM 433



Range 1: 24 to 528







N D+ LKSFEPAVLKQGEEIHNEVEFEWLRQFWFQGNRY+KCTDWWCQPMAQLE LWKKM
Sbjct 374 NGDICLKSFEPAVLKQGEEIHNEVEFEWLRQFWFQGNRYKKCTDWWCQPMAQLEELWKKM 433

ECRPYWEKDDASMPLPFDLTD+VSELRGQLLEA+P
Sbjct 494 ECRPYWEKDDASMPLPFDLTDVVSELRGQLLEARP 528

Range 1: 24 to 559




Query 241 AVAVYSYSCEGT-----------VCSWKKQPC----------PEEESEDDSHLEGRDPDI 279

AVAVYSYSCE + S P PE ESEDDS+LEGRDPD



+KCTDWWCQPMAQLE LWKKMEGVTNAVLHEVKREGLPVEQRNEILTAILASLTARQNLR
Sbjct 444 KKCTDWWCQPMAQLEELWKKMEGVTNAVLHEVKREGLPVEQRNEILTAILASLTARQNLR 503

REWHARCQSRIARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRGQLLEA+P
Sbjct 504 REWHARCQSRIARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRGQLLEARP 559

Range 1: 1 to 505




AVAVYSYSCEG PEEESEDDSH E RDPDIWHVGFKISWDIETPGL IPLH
Sbjct 241 AVAVYSYSCEG----------PEEESEDDSHFESRDPDIWHVGFKISWDIETPGLTIPLH 290

QGDCYFMLDDLNATHQHC+LAGSQPRFSSTH+VAECSTGTLDYILQRCQLALQNV DDVD
Sbjct 291 QGDCYFMLDDLNATHQHCILAGSQPRFSSTHQVAECSTGTLDYILQRCQLALQNVRDDVD 350

N DVSLKSFEPAVLKQGEEIHNEVEFEWLR FWFQGNRYRKCTDWWCQP+A LEALWKKM
Sbjct 351 NGDVSLKSFEPAVLKQGEEIHNEVEFEWLRXFWFQGNRYRKCTDWWCQPVAHLEALWKKM 410

EGVTNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHARCQS+IARTLPADQKP
Sbjct 411 EGVTNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHARCQSQIARTLPADQKP 470

ECRPYWEKDD SMPLPFDLTDIVSELRGQLL+AKP
Sbjct 471 ECRPYWEKDDISMPLPFDLTDIVSELRGQLLKAKP 505

Range 1: 1 to 505





AVAVYSYSCEG PEEESEDDSH E RDPDIWHVGFKISWDIETPG AIPLH
Sbjct 241 AVAVYSYSCEG----------PEEESEDDSHFESRDPDIWHVGFKISWDIETPGSAIPLH 290

QGDCYFMLDDL ATHQHCVLAGSQPRFSSTH+VAECSTGTLDYILQRCQLALQNV +DVD
Sbjct 291 QGDCYFMLDDLYATHQHCVLAGSQPRFSSTHQVAECSTGTLDYILQRCQLALQNVRNDVD 350

N D+SLK+FEPAVLKQGEEIHNEVEFEWLRQFWFQGN YRKCTDWWCQP+AQLEALWKKM
Sbjct 351 NGDISLKTFEPAVLKQGEEIHNEVEFEWLRQFWFQGNGYRKCTDWWCQPVAQLEALWKKM 410

EGVTNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHARCQS+IARTLPADQKP
Sbjct 411 EGVTNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHARCQSQIARTLPADQKP 470

ECRPYWEKDD SMPLPFDLTDIVSELRGQLL+AKP
Sbjct 471 ECRPYWEKDDISMPLPFDLTDIVSELRGQLLKAKP 505

atys]
Range 1: 10 to 499




Sbjct 190 RAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLVDRSAVAVYSYSCEG---- 245

PEEES+DDSH EGRDPDIWHVGFKISWDIETPGLAIPLHQGDCYFMLDDLNATH
Sbjct 246 ------PEEESDDDSHFEGRDPDIWHVGFKISWDIETPGLAIPLHQGDCYFMLDDLNATH 299

QHCVLAGSQPRFSSTHRVAECSTGTLDYILQRCQLALQNV DDVDN DVSLKSFEPAVLK
Sbjct 300 QHCVLAGSQPRFSSTHRVAECSTGTLDYILQRCQLALQNVRDDVDNGDVSLKSFEPAVLK 359




atys]
Range 1: 3 to 492










sabaeus]
Range 1: 6 to 496



Query 195 SRAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLVDRSAVAVYSYSCEGTVC 254

SRAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLVDRSAVAVYSYSCEG
Sbjct 186 SRAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLVDRSAVAVYSYSCEG--- 242
Query 255 SWKKQPCPEEESEDDSHLEGRDPDIWHVGFKISWDIETPGLAIPLHQGDCYFMLDDLNAT 314

PEEES+DDSH EGRDPDIWHVGFKISWDIETPGLAIPLHQGDCYFMLDDLNAT
Sbjct 243 -------PEEESDDDSHFEGRDPDIWHVGFKISWDIETPGLAIPLHQGDCYFMLDDLNAT 295
Query 315 HQHCVLAGSQPRFSSTHRVAECSTGTLDYILQRCQLALQNVCDDVDNDDVSLKSFEPAVL 374

HQHCVLAGSQPRFSSTHRVAECSTGTLDYILQRCQLALQNV DDVDN DVSLKSFEPAVL
Sbjct 296 HQHCVLAGSQPRFSSTHRVAECSTGTLDYILQRCQLALQNVRDDVDNGDVSLKSFEPAVL 355
Query 375 KQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVTNAVLHEVKRE 434

KQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVTNAVL EVKRE
Sbjct 356 KQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVTNAVLREVKRE 415
Query 435 GLPVEQRNEILTAILASLTARQNLRREWHARCQSRIARTLPADQKPECRPYWEKDDASMP 494

GLPVEQRNEILTAILASLTARQNLRREWHARCQSRIARTLPADQKPECRPYWEKDD SMP
Sbjct 416 GLPVEQRNEILTAILASLTARQNLRREWHARCQSRIARTLPADQKPECRPYWEKDDVSMP 475
Query 495 LPFDLTDIVSELRGQLLEAKP 515

LPFDLTDIVSELRGQLLEAKP
Sbjct 476 LPFDLTDIVSELRGQLLEAKP 496

Range 1: 24 to 528





AVAVYSYSCEG PEEES+DDSHLEGRDPD WHVGFKISWDIETPGLAIPLH
Sbjct 264 AVAVYSYSCEG----------PEEESDDDSHLEGRDPDTWHVGFKISWDIETPGLAIPLH 313


N DVSLKSFEPAVLKQGEEIHNEVEFEWLRQFWFQGNRY+KCTDWWCQPM QLE LWKKM
Sbjct 374 NGDVSLKSFEPAVLKQGEEIHNEVEFEWLRQFWFQGNRYKKCTDWWCQPMTQLEELWKKM 433

EGVTNAVL EVKREGLPVEQRNEILTAILASLT RQNLRREWHARCQ RIARTLP DQKP
Sbjct 434 EGVTNAVLREVKREGLPVEQRNEILTAILASLTTRQNLRREWHARCQCRIARTLPVDQKP 493

ECRPYWEK+D SMPLPFDLTD+VSELRGQLLEAKP
Sbjct 494 ECRPYWEKEDPSMPLPFDLTDVVSELRGQLLEAKP 528

Range 1: 16 to 506






KQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVTNAVLHEVKRE
Sbjct 366 KQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVTNAVLHEVKRE 425

GLP+EQRNEILTAILASLTARQNLRREWHARCQSRIARTLPADQKPECRPYWEKDD SMP
Sbjct 426 GLPMEQRNEILTAILASLTARQNLRREWHARCQSRIARTLPADQKPECRPYWEKDDVSMP 485

LPFDLTD+VSELRGQLLEAKP
Sbjct 486 LPFDLTDLVSELRGQLLEAKP 506

coquereli]
Range 1: 1 to 505






N DVSLKSFEPAVLKQGEEIHNEVEFEWLRQFWFQGNRY+KCTDWWCQPM QLE WKKM
Sbjct 351 NGDVSLKSFEPAVLKQGEEIHNEVEFEWLRQFWFQGNRYKKCTDWWCQPMTQLEERWKKM 410


ECRPYWEK+D SMPLPFDLTDIVS+LRGQLLEAKP
Sbjct 471 ECRPYWEKEDPSMPLPFDLTDIVSDLRGQLLEAKP 505

FTO [Homo sapiens]
FTO [Homo sapiens]
FTO [Homo sapiens]
FTO [Homo sapiens]
FTO [Homo sapiens]
FTO [Homo sapiens]
FTO [Homo sapiens]
FTO [Homo sapiens]
Fto [Homo sapiens]
Range 1: 20 to 495



Query 210 QKMPYLKEEPYFGMGKMAVSWHHDENLVDRSAVAVYSYSCEGTVCSWKKQPCPEEESEDD 269

QKMPYLKEEPYFGMGKMAVSWHHDENLVDRSAVAVYSYSCEG PEEESEDD
Sbjct 200 QKMPYLKEEPYFGMGKMAVSWHHDENLVDRSAVAVYSYSCEG----------PEEESEDD 249
Query 270 SHLEGRDPDIWHVGFKISWDIETPGLAIPLHQGDCYFMLDDLNATHQHCVLAGSQPRFSS 329

SHLEGRDPDIWHVGFKISWDIETPGLAIPLHQGDCYFMLDDLNATHQHCVLAGSQPRFSS
Sbjct 250 SHLEGRDPDIWHVGFKISWDIETPGLAIPLHQGDCYFMLDDLNATHQHCVLAGSQPRFSS 309
Query 330 THRVAECSTGTLDYILQRCQLALQNVCDDVDNDDVSLKSFEPAVLKQGEEIHNEVEFEWL 389

THRVAECSTGTLDYILQRCQLALQNVCDDVDNDDVSLKSFEPAVLKQGEEIHNEVEFEWL
Sbjct 310 THRVAECSTGTLDYILQRCQLALQNVCDDVDNDDVSLKSFEPAVLKQGEEIHNEVEFEWL 369
Query 390 RQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVTNAVLHEVKREGLPVEQRNEILTAIL 449

RQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVTNAVLHEVKREGLPVEQRNEILTAIL
Sbjct 370 RQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVTNAVLHEVKREGLPVEQRNEILTAIL 429
Query 450 ASLTARQNLRREWHARCQSRIARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRGQ 509

ASLTARQNLRREWHARCQSRIARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRGQ
Sbjct 430 ASLTARQNLRREWHARCQSRIARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRGQ 489
Query 510 LLEAKP 515

LLEAKP
Sbjct 490 LLEAKP 495

Range 1: 3 to 478








LLEAKP

Range 1: 2 to 485








Query 496 PFDLTDIVSELRGQ 509

PFDLTDIVSELR +
Sbjct 472 PFDLTDIVSELRAE 485

Range 1: 3 to 476







Query 510 LLEA 513

LLEA
Sbjct 473 LLEA 476

fascicularis]
Range 1: 3 to 484







Query 496 PFDLTDIVSELR 507

PFDLTDIVSELR
Sbjct 473 PFDLTDIVSELR 484

Range 1: 4 to 479








LLEAKP

Range 1: 20 to 492








Query 510 LLE 512

LLE
Sbjct 490 LLE 492

Range 1: 16 to 499







KQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVTNAVLHEVKRE
Sbjct 366 KQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVTNAVLHEVKRE 425

GLPVEQRNEILTAILASLTARQNLRREWHARCQSRIARTLPADQKPECRPYWEKDD SMP
Sbjct 426 GLPVEQRNEILTAILASLTARQNLRREWHARCQSRIARTLPADQKPECRPYWEKDDVSMP 485
Query 495 LPFDLTDIVSELRG 508

LPFDLTDIVSELRG
Sbjct 486 LPFDLTDIVSELRG 499

Range 1: 4 to 476








Query 510 LLE 512

LLE
Sbjct 474 LLE 476

Range 1: 1 to 479










coquereli]
Range 1: 1 to 498







N DVSLKSFEPAVLKQGEEIHNEVEFEWLRQFWFQGNRY+KCTDWWCQPM QLE WKKM
Sbjct 351 NGDVSLKSFEPAVLKQGEEIHNEVEFEWLRQFWFQGNRYKKCTDWWCQPMTQLEERWKKM 410

Query 481 ECRPYWEKDDASMPLPFDLTDIVSELRG 508

ECRPYWEK+D SMPLPFDLTDIVS+LRG
Sbjct 471 ECRPYWEKEDPSMPLPFDLTDIVSDLRG 498

Range 1: 1 to 468







Query 421 EGVTNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHARCQS 468

EGVTNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHAR +
Sbjct 421 EGVTNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHARATT 468

Range 1: 1 to 468







EGVTNAVLHEVKREGLP+EQRNEILTAILASLTARQNLRREWHAR +
Sbjct 421 EGVTNAVLHEVKREGLPMEQRNEILTAILASLTARQNLRREWHARATT 468

Range 1: 1 to 467







Query 421 EGVTNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHARCQ 467

Sbjct 421 EGVTNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHARVE 467

Range 1: 1 to 465







Query 421 EGVTNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHAR 465

EGVTNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHAR
Sbjct 421 EGVTNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHAR 465

Range 1: 1 to 464







Query 421 EGVTNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHA 464

EGVTNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHA
Sbjct 421 EGVTNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHA 464

Range 1: 1 to 468








EGVTNAVLHEVK EGLP+EQRNEILTAILASLTARQNLRREWHAR +
Sbjct 421 EGVTNAVLHEVKGEGLPMEQRNEILTAILASLTARQNLRREWHARATT 468

Range 1: 1 to 504





AVAVYSYSCEG+ E+ES+DDS+ EGRDPD WHVGFKISWDIETPGLAIPLH
Sbjct 240 AVAVYSYSCEGS----------EDESDDDSNFEGRDPDTWHVGFKISWDIETPGLAIPLH 289

QGDCYFMLDDLNATHQHCVLAGSQPRFSSTHRVAECSTGTLDYILQR Q+ALQN+ DD++
Sbjct 290 QGDCYFMLDDLNATHQHCVLAGSQPRFSSTHRVAECSTGTLDYILQRSQVALQNIRDDLE 349

N DVSLKSFEPA+LKQGEEIHNEVEFEWLRQFWFQG+RYRKCTDWWC+PM++LE LWKKM
Sbjct 350 NGDVSLKSFEPAILKQGEEIHNEVEFEWLRQFWFQGSRYRKCTDWWCEPMSKLEGLWKKM 409

E VTNAVL EVKREGLPVEQRNEILTAILA LT RQNLRREWHARCQ RIARTLP DQKP
Sbjct 410 ESVTNAVLREVKREGLPVEQRNEILTAILAPLTTRQNLRREWHARCQCRIARTLPVDQKP 469

+CRPYWEKDDASMPLPFDLTDIVSELR QLLEAKP
Sbjct 470 DCRPYWEKDDASMPLPFDLTDIVSELRAQLLEAKP 504

Range 1: 1 to 467








EGVTNAVLHEVK EGLP+EQRNEILTAILASLTARQNLRREWHAR +
Sbjct 421 EGVTNAVLHEVKGEGLPMEQRNEILTAILASLTARQNLRREWHARVE 467

Range 1: 1 to 504





AVAVYSYSCEG PEEESEDDSHLEGRDPD WHVGFKISWDIETPGLAIPLH
Sbjct 240 AVAVYSYSCEG----------PEEESEDDSHLEGRDPDTWHVGFKISWDIETPGLAIPLH 289

QGDCYFMLDDLNATHQHCVLAGSQPRFSSTHRVAECS GTLDYILQRCQ+ALQNV DVD
Sbjct 290 QGDCYFMLDDLNATHQHCVLAGSQPRFSSTHRVAECSAGTLDYILQRCQVALQNVRGDVD 349

N DVSLKSFEPAVLKQGEEIHNEVEFEWLRQFWFQGNRY+KCTDWWCQPM QLE LWK+M
Sbjct 350 NGDVSLKSFEPAVLKQGEEIHNEVEFEWLRQFWFQGNRYKKCTDWWCQPMTQLEELWKRM 409

EGVTNAVLHEVKREGLPVEQRNEILTA+L LT RQNLRREWHARCQ RIARTLP DQKP
Sbjct 410 EGVTNAVLHEVKREGLPVEQRNEILTAVLPLLTTRQNLRREWHARCQCRIARTLPVDQKP 469

ECRPYWEKDD SMPLPFDLTDIVSELR QLLEAKP
Sbjct 470 ECRPYWEKDDPSMPLPFDLTDIVSELRSQLLEAKP 504

Range 1: 1 to 506





AVAVY+YSC+ EEESEDDSHLEGRDPDIWHVGFKISWDIETPGLAIPLH
Sbjct 241 AVAVYNYSCDEDS---------EEESEDDSHLEGRDPDIWHVGFKISWDIETPGLAIPLH 291

QGDCYFMLDDLNATHQHCVLAGSQPRFSSTHRVAECSTGTLDYI QRCQLALQNV DDVD
Sbjct 292 QGDCYFMLDDLNATHQHCVLAGSQPRFSSTHRVAECSTGTLDYISQRCQLALQNVRDDVD 351

N D+SLK+FEPAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPM LE LWKKM
Sbjct 352 NGDISLKTFEPAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMTHLEGLWKKM 411

EGVTNAVLHEVKREGLPVEQRNEILTAILA LT RQNLRREWHARCQSRIARTLP DQKP
Sbjct 412 EGVTNAVLHEVKREGLPVEQRNEILTAILALLTTRQNLRREWHARCQSRIARTLPGDQKP 471

ECRPYWEKDD SMPLPFDLTDIVSELRG LLEAKP
Sbjct 472 ECRPYWEKDDPSMPLPFDLTDIVSELRGLLLEAKP 506

Range 1: 1 to 504









Range 1: 1 to 468








EGVTNAVLHEVK EGLP+EQRNEILTAILASLTARQNLRREWHAR S
Sbjct 421 EGVTNAVLHEVKGEGLPMEQRNEILTAILASLTARQNLRREWHARGGS 468
Range 1: 1 to 504










Range 1: 1 to 504





AVAVY+YSCEG P++ES+DDS+LEGRDPDIWHVGFKISWDIETPGLAIPLH
Sbjct 240 AVAVYNYSCEG----------PDDESDDDSNLEGRDPDIWHVGFKISWDIETPGLAIPLH 289

QGDCYFMLDDLNATHQHCVLAGSQPRFSSTHRVAECS GTLDYILQRCQLALQNV DD D
Sbjct 290 QGDCYFMLDDLNATHQHCVLAGSQPRFSSTHRVAECSMGTLDYILQRCQLALQNVRDDAD 349

V+LKSFEPAVLKQGEEIHNEVEFEWLRQ+WFQGNRY+KCTDWWC+PM QLE LWKKM
Sbjct 350 GTAVTLKSFEPAVLKQGEEIHNEVEFEWLRQYWFQGNRYKKCTDWWCEPMTQLEGLWKKM 409

E VTNAVLHEVKREGLPVEQRNEILTAILA LT RQNLRREWHARCQ RIARTLP DQKP
Sbjct 410 EDVTNAVLHEVKREGLPVEQRNEILTAILAPLTTRQNLRREWHARCQCRIARTLPVDQKP 469

+CRPYWEKDD SMPLPFDLT++VSELRG LLEAKP
Sbjct 470 DCRPYWEKDDPSMPLPFDLTELVSELRGLLLEAKP 504

Range 1: 1 to 504










FTO [Homo sapiens]
FTO [Homo sapiens]
Range 1: 1 to 463



Query 217 EEPYFGMGKMAVSWHHDENLVDRSAVAVYSYSCEGTVCSWKKQPCPEEESEDDSHLEGRD 276

EEPYFGMGKMAVSWHHDENLVDRSAVAVYSYSCEG PEEESEDDSHLEGRD
Sbjct 181 EEPYFGMGKMAVSWHHDENLVDRSAVAVYSYSCEG----------PEEESEDDSHLEGRD 230
Query 277 PDIWHVGFKISWDIETPGLAIPLHQGDCYFMLDDLNATHQHCVLAGSQPRFSSTHRVAEC 336

PDIWHVGFKISWDIETPGLAIPLHQGDCYFMLDDLNATH+HCVLAGSQPRFSSTHRVAEC
Sbjct 231 PDIWHVGFKISWDIETPGLAIPLHQGDCYFMLDDLNATHKHCVLAGSQPRFSSTHRVAEC 290
Query 337 STGTLDYILQRCQLALQNVCDDVDNDDVSLKSFEPAVLKQGEEIHNEVEFEWLRQFWFQG 396

STGTLDYILQRCQLALQNVCDDVDNDDVSLKSFEPAVLKQGEEIHNEVEFEWLRQFWFQG
Sbjct 291 STGTLDYILQRCQLALQNVCDDVDNDDVSLKSFEPAVLKQGEEIHNEVEFEWLRQFWFQG 350
Query 397 NRYRKCTDWWCQPMAQLEALWKKMEGVTNAVLHEVKREGLPVEQRNEILTAILASLTARQ 456

NRYRKCTDWWCQPMAQLEALWKKMEGVTNAVLHEVKREGLPVEQRNEILTAILASLTARQ
Sbjct 351 NRYRKCTDWWCQPMAQLEALWKKMEGVTNAVLHEVKREGLPVEQRNEILTAILASLTARQ 410
Query 457 NLRREWHARCQSRIARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRGQ 509

NLRREWHARCQSRIARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRGQ
Sbjct 411 NLRREWHARCQSRIARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRGQ 463

Range 1: 1 to 479









Range 1: 1 to 465







Query 421 EGVTNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHAR 465

E VTNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHAR
Sbjct 421 EAVTNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHAR 465

Range 1: 1 to 467








E VTNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHAR +
Sbjct 421 EAVTNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHARVE 467

Range 1: 1 to 505





AVAVYSYSCEG PEEESEDD LEGRDPDIWHVGFKISWDIETPGLAIPLH
Sbjct 241 AVAVYSYSCEG----------PEEESEDDPQLEGRDPDIWHVGFKISWDIETPGLAIPLH 290

QGDCYFMLDDLNATHQHCVLAG PRFSSTHRVAECSTGTLDYI+Q CQLALQN+ D+ D
Sbjct 291 QGDCYFMLDDLNATHQHCVLAGLPPRFSSTHRVAECSTGTLDYIVQHCQLALQNIRDEAD 350

N DVSLKS EPAVLKQGEEIHNEVEFEWLRQFWFQGNRY+KCTDWWCQPM QLE LWKKM
Sbjct 351 NGDVSLKSLEPAVLKQGEEIHNEVEFEWLRQFWFQGNRYKKCTDWWCQPMTQLEELWKKM 410

EGVTNAVLHEV+REG+PVEQRNEILTAILASLT RQNLRREWHARCQ RIARTLP DQKP
Sbjct 411 EGVTNAVLHEVRREGVPVEQRNEILTAILASLTTRQNLRREWHARCQCRIARTLPVDQKP 470

ECRPYWEKDD SMPLPFDLTDI+SELRG LLEAKP
Sbjct 471 ECRPYWEKDDPSMPLPFDLTDIISELRGLLLEAKP 505

Range 1: 1 to 505






QGDCYFMLDDLNATHQHCVLAG PRFSSTHRVAECSTGTLDYI+QRCQLALQN+ D+ D
Sbjct 291 QGDCYFMLDDLNATHQHCVLAGLPPRFSSTHRVAECSTGTLDYIVQRCQLALQNIRDETD 350


E VTNAVLHEV+REG+PVEQRNEILTAILASLT RQNLRREWHARCQ RIARTLP DQKP
Sbjct 411 EAVTNAVLHEVRREGVPVEQRNEILTAILASLTTRQNLRREWHARCQCRIARTLPVDQKP 470


Range 1: 46 to 549





AVAVYSYSCEG PEEESEDD LEGRDPD WHVGFKISWDIETPGLAIPLH
Sbjct 285 AVAVYSYSCEG----------PEEESEDDPQLEGRDPDTWHVGFKISWDIETPGLAIPLH 334

QGDCYFMLDDLNATHQHCVLAG PRFSSTHRVAECSTGTLDYILQRCQLALQNV D+ D
Sbjct 335 QGDCYFMLDDLNATHQHCVLAGLPPRFSSTHRVAECSTGTLDYILQRCQLALQNVRDEAD 394

N DVSLKSFEP VLKQGEEIHNEVEFEWLRQ+WFQGNRYRKCTDWWCQPM QLE LWKKM
Sbjct 395 NGDVSLKSFEPVVLKQGEEIHNEVEFEWLRQYWFQGNRYRKCTDWWCQPMTQLEGLWKKM 454

EGVTNAVLHEV+REG+PVEQRNEILTAILA LT RQNLRREWHARCQSRIARTLP DQKP
Sbjct 455 EGVTNAVLHEVRREGVPVEQRNEILTAILALLTTRQNLRREWHARCQSRIARTLPVDQKP 514


Range 1: 46 to 549









Range 1: 15 to 519





AVAVYSYSCEG P+EESEDD LEGRDPDIWHVGFKISWDIETPGLAIPLH
Sbjct 255 AVAVYSYSCEG----------PDEESEDDPQLEGRDPDIWHVGFKISWDIETPGLAIPLH 304

QGDCYFMLDDLNATHQHCVLAG PRFSSTHRVAECSTGTLDYILQRCQ ALQN+ D+ D
Sbjct 305 QGDCYFMLDDLNATHQHCVLAGLPPRFSSTHRVAECSTGTLDYILQRCQSALQNIRDEAD 364

N +VSLKS EP VLK GEEIHNEVEFEWLRQFWFQGNRY++CTDWWCQPM QLE LWKKM
Sbjct 365 NGEVSLKSLEPVVLKHGEEIHNEVEFEWLRQFWFQGNRYKRCTDWWCQPMTQLEELWKKM 424

EG+TNAVL EV+REG PVEQRNEILTAILA+LTARQNLRREWHARCQSRIARTLPADQKP
Sbjct 425 EGLTNAVLREVRREGTPVEQRNEILTAILATLTARQNLRREWHARCQSRIARTLPADQKP 484

ECRPYWEKDD SMPLPFDLTDI+SELR LLEAKP
Sbjct 485 ECRPYWEKDDPSMPLPFDLTDIISELRSLLLEAKP 519

Range 1: 1 to 505






QGDCYFMLDDLNATHQHCVLAG PRFSSTHRVAECSTGTLDYI+QRCQLALQN+ D+ D
Sbjct 291 QGDCYFMLDDLNATHQHCVLAGLPPRFSSTHRVAECSTGTLDYIVQRCQLALQNIRDETD 350


E VTNAVLHEV++EG+PVEQRNEILTAILASLT RQNLRREWHARCQ RIARTLP DQKP
Sbjct 411 EAVTNAVLHEVRQEGVPVEQRNEILTAILASLTTRQNLRREWHARCQCRIARTLPVDQKP 470


Range 1: 1 to 504






QGDCYFMLDDLNATHQHCVLAG PRFSSTHRVAECSTGTLDYILQRCQ+ALQNV D D
Sbjct 290 QGDCYFMLDDLNATHQHCVLAGLPPRFSSTHRVAECSTGTLDYILQRCQVALQNVRDGAD 349

DVSLKSFEPAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKC+DWWCQPMAQLE LWKKM
Sbjct 350 GGDVSLKSFEPAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCSDWWCQPMAQLEELWKKM 409

EGVTNAVL EV+REG+PVEQRNEILTAILASLT RQNLRREWHARCQSRIARTLP DQKP
Sbjct 410 EGVTNAVLREVRREGVPVEQRNEILTAILASLTTRQNLRREWHARCQSRIARTLPVDQKP 469

ECRPYWEKDD SMPLPFDLTD+VSELRG LLEAKP
Sbjct 470 ECRPYWEKDDPSMPLPFDLTDVVSELRGLLLEAKP 504

Range 1: 1 to 505






QGDCYFMLDDLNATHQHCVLAG PRFSSTHRVAECSTGTLDYILQRCQLALQNV ++ D
Sbjct 291 QGDCYFMLDDLNATHQHCVLAGLPPRFSSTHRVAECSTGTLDYILQRCQLALQNVRNEAD 350

N + SLKS EPAVLKQGEEIHNEVEFEWLRQFWFQGNRY+KCT+WWCQPM QLE LWKKM
Sbjct 351 NGEFSLKSLEPAVLKQGEEIHNEVEFEWLRQFWFQGNRYKKCTNWWCQPMTQLEELWKKM 410

EGVTNAVLHEV+REG PVEQRN+ILTAILA LT RQNLRREWHARCQ RIAR+LPADQKP
Sbjct 411 EGVTNAVLHEVRREGAPVEQRNKILTAILAVLTTRQNLRREWHARCQCRIARSLPADQKP 470

ECRPYWEKDD SMPLPF+LTDIVSELRG LLEAKP
Sbjct 471 ECRPYWEKDDPSMPLPFELTDIVSELRGLLLEAKP 505

Range 1: 1 to 504







DVSLKSFEPAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKC+DWWCQPMAQLE LWKKM
Sbjct 350 GGDVSLKSFEPAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCSDWWCQPMAQLEELWKKM 409

EGVTNAVLHEV+REG+PVEQRNEILTAILA LT+RQNLRREWHARCQSRIARTLP DQKP
Sbjct 410 EGVTNAVLHEVRREGVPVEQRNEILTAILALLTSRQNLRREWHARCQSRIARTLPVDQKP 469


Range 1: 1 to 505





QGDCYFMLDDLNATHQHCVLAG PRFSSTHRVAECSTGTLDYILQRCQLALQNV ++ D
Sbjct 291 QGDCYFMLDDLNATHQHCVLAGLPPRFSSTHRVAECSTGTLDYILQRCQLALQNVRNEAD 350

N +VSLKS EPAVLKQGEEIHNEVEFEWLRQFWFQGNRY+KCTDWW QPM QLE LWKKM
Sbjct 351 NGEVSLKSLEPAVLKQGEEIHNEVEFEWLRQFWFQGNRYKKCTDWWWQPMTQLEELWKKM 410

EGVTNAVL EV+REG PVEQRN+ILTAILA LT RQNLRREWHARCQ RIAR+LPADQKP
Sbjct 411 EGVTNAVLQEVRREGAPVEQRNKILTAILAVLTTRQNLRREWHARCQCRIARSLPADQKP 470


Range 1: 15 to 519





AVAVYSYSCEG P+EESEDD LEGRDPDIWHVGFKISWDIETPGLAIPLH
Sbjct 255 AVAVYSYSCEG----------PDEESEDDPQLEGRDPDIWHVGFKISWDIETPGLAIPLH 304

QGDCYFMLDDLNATHQHCVLAG PRFSSTHRVAECSTGTLDYIL+RCQ ALQN+ D+ D
Sbjct 305 QGDCYFMLDDLNATHQHCVLAGLPPRFSSTHRVAECSTGTLDYILERCQSALQNIRDEAD 364

N +VSLKS EP VLK GEEIHNEVEFEWLRQFWFQGNRY++CTDWWCQPM QLE LWKKM
Sbjct 365 NGEVSLKSLEPVVLKHGEEIHNEVEFEWLRQFWFQGNRYKRCTDWWCQPMTQLEELWKKM 424

EG+TNAVL EV+REG PVEQRNEILTAILA+LTARQNLRREWHARCQSRIARTLPADQKP
Sbjct 425 EGLTNAVLREVRREGTPVEQRNEILTAILATLTARQNLRREWHARCQSRIARTLPADQKP 484
ECRPYWEKDD SMPLPFDLTDI+SELR LLEAKP
Sbjct 485 ECRPYWEKDDPSMPLPFDLTDIISELRSLLLEAKP 519

Range 1: 1 to 504







D SLKSFEPAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKC+DWWCQPMAQLE LWKKM
Sbjct 350 GGDASLKSFEPAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCSDWWCQPMAQLEELWKKM 409



Range 1: 65 to 568






QGDCYFMLDDLNATHQHCVLAG PRFSSTHRVAECSTGTLDYIL+RCQLALQNV ++VD
Sbjct 354 QGDCYFMLDDLNATHQHCVLAGLPPRFSSTHRVAECSTGTLDYILERCQLALQNVRNEVD 413

N DVSLKSFEPAVLKQGEEIHNEVEFEWLRQ+WFQGNRYRKCTDWWCQPM QLE LWKKM
Sbjct 414 NGDVSLKSFEPAVLKQGEEIHNEVEFEWLRQYWFQGNRYRKCTDWWCQPMTQLEGLWKKM 473


ECRPYWEKDD SMPLPFDLTDIVSELR LLE KP
Sbjct 534 ECRPYWEKDDPSMPLPFDLTDIVSELRSLLLEGKP 568

Range 1: 1 to 504






DVSLKSFEP VLKQGEEIHNEVEFEWLRQFWFQGNRYRKC+DWWCQPMAQLE LWKKM
Sbjct 350 GGDVSLKSFEPVVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCSDWWCQPMAQLEELWKKM 409

EGVTNAVL EV+REG+PVEQRNEILTAILA LT+RQNLRREWHARCQSRIARTLP DQKP
Sbjct 410 EGVTNAVLREVRREGVPVEQRNEILTAILALLTSRQNLRREWHARCQSRIARTLPVDQKP 469


Range 1: 46 to 549









Range 1: 1 to 504






QGDCYFMLDDLNATHQHCVLAG PRFSSTHRVAECS GTLDYILQRCQ+ALQNV D D
Sbjct 290 QGDCYFMLDDLNATHQHCVLAGLPPRFSSTHRVAECSAGTLDYILQRCQVALQNVRDGAD 349

DVSLKS EP+VLKQGEEIHNEVEFEWLRQFWFQGNRYRKC+DWWCQPMAQLE LWKKM
Sbjct 350 GGDVSLKSLEPSVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCSDWWCQPMAQLEELWKKM 409


ECRPYWEKDD SMPLPFDLTD VSELRG LLEAKP
Sbjct 470 ECRPYWEKDDPSMPLPFDLTDAVSELRGLLLEAKP 504
Range 1: 1 to 504










Range 1: 1 to 499









ECRPYWEKDD SMPLPFDLTDIVSELRG+
Sbjct 470 ECRPYWEKDDPSMPLPFDLTDIVSELRGEF 499

Range 1: 46 to 549







EGVTNAVLHEV+REG+PVEQR EILTAILA LT RQNLRREWHARCQSRIARTLP DQKP
Sbjct 455 EGVTNAVLHEVRREGVPVEQRTEILTAILALLTTRQNLRREWHARCQSRIARTLPVDQKP 514


Range 1: 1 to 458







Sbjct 411 EGVTNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHARATT 458

Range 1: 1 to 504








EGVTNAVLHEV+REG+PVEQR EILTAILA LT RQNLRREWHARCQSRIARTLP DQKP
Sbjct 410 EGVTNAVLHEVRREGVPVEQRTEILTAILALLTTRQNLRREWHARCQSRIARTLPVDQKP 469



Max Total
Query E Per.
0.0 100.00 NP_001350823.1
0.0 96.01 NP_001073901.1
0.0 95.82 BAG53322.1
0.0 95.82 XP_024781684.1
0.0 95.82 BAB21843.2
0.0 95.63 XP_510968.2
0.0 95.63 XP_032013254.1
0.0 94.22 NP_001350820.1
0.0 94.03 XP_024781683.1
0.0 95.06 XP_003263101.1
0.0 94.68 PNJ62567.1
0.0 93.84 XP_009429081.1
0.0 93.84 XP_032013253.1
0.0 94.68 NP_001126250.1
0.0 94.68 XP_010356591.2
0.0 94.49 XP_005591989.1
0.0 94.49 XP_025225777.1
0.0 94.49 XP_023065721.2
0.0 93.28 XP_030652817.1
0.0 94.49 XP_033074312.1
0.0 95.56 PNI63967.1
0.0 94.11 XP_011760503.1
0.0 95.01 PNI63969.1
0.0 94.30 XP_007991498.1
0.0 92.91 XP_009248996.1
0.0 94.11 XP_011801988.1
0.0 93.92 XP_011827312.1
0.0 92.72 XP_025225776.1
0.0 94.59 PNJ62570.1
0.0 94.05 PNJ62571.1
0.0 93.16 XP_012303365.1
0.0 92.97 XP_008984120.1
0.0 94.04 XP_031514106.1
0.0 94.41 XP_014981634.1
0.0 94.40 XP_003916924.2
0.0 92.40 XP_003937323.1
0.0 93.86 XP_034796072.1
0.0 92.21 XP_032111506.1
0.0 91.83 XP_017385575.1
0.0 92.40 XP_033090538.1
0.0 92.02 XP_017719562.1
0.0 94.32 XP_011921553.1
0.0 87.79 XP_035138572.1
0.0 94.14 XP_007991499.1
0.0 94.32 XP_011921571.1
0.0 92.71 XP_009248997.1
0.0 91.06 XP_012628070.1
0.0 93.75 XP_011760506.1
0.0 90.49 XP_012508119.1
0.0 95.37 4ZS2_A
0.0 95.37 3LFM_A
0.0 93.86 XP_009194707.2
0.0 95.35 4QKN_A
0.0 94.23 XP_015298227.1
0.0 94.06 XP_028697425.1
0.0 94.97 5DAB_A
0.0 95.34 5F8P_A
0.0 95.34 6AKW_A
0.0 91.06 NP_001350826.1
0.0 90.37 XP_012508120.1
alpha-ketoglutarate-dependent dioxygenase FTO [Puma concolor] 968 968 97%
0.0 89.65 XP_025776378.1
0.0 88.59 XP_012662320.1
0.0 88.21 XP_015343973.1
0.0 88.02 XP_027794874.1
0.0 87.83 XP_026248055.1
0.0 88.21 NP_001186297.1
0.0 90.13 XP_006148441.1
0.0 87.64 XP_005318239.1
0.0 95.25 5ZMD_A
0.0 89.54 XP_025225781.1
0.0 87.45 XP_014683258.1
0.0 87.26 XP_008511378.1
0.0 87.64 XP_025302887.1
0.0 87.64 XP_025867549.1
0.0 86.88 XP_036690105.1
0.0 87.64 XP_003998090.1
0.0 87.07 XP_005608321.1
0.0 87.07 XP_006186034.1
0.0 87.45 XP_026900282.1
0.0 87.45 XP_019311473.1
0.0 87.26 XP_006207900.1
0.0 86.50 XP_007167659.1
0.0 87.07 XP_007096738.1
0.0 87.26 XP_027949643.1
0.0 87.26 XP_027474669.1
0.0 86.88 XP_030155469.1
0.0 87.07 XP_025708148.1
0.0 87.33 F1PLN3.3
0.0 86.50 XP_006732653.1
0.0 86.31 XP_035937580.1
0.0 94.99 XP_016879145.1
0.0 86.50 XP_021560370.1
0.0 86.12 ACT65741.1
0.0 95.19 XP_016879146.1
0.0 86.12 AEY68263.1
0.0 85.36 XP_004371639.1
0.0 95.58 XP_024306205.1
0.0 95.59 NP_001350917.1
fat mass and obesity-associated protein [Sus scrofa] 937 937 100%
0.0 85.93 ACY82516.1
0.0 86.31 XP_034881088.1
Alignments:
Range 1: 1 to 526






Query 361 PAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVISVELYK 420

PAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVISVELYK
Query 421 ELGLMSPRLIRHKATNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHARCQSR 480

ELGLMSPRLIRHKATNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHARCQSR
Sbjct 421 ELGLMSPRLIRHKATNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHARCQSR 480


construct]
Range 1: 1 to 505







Sbjct 361 PAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGV------- 413

Sbjct 414 --------------TNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHARCQSR 459


Range 1: 1 to 505







PAVLKQGEEIHNEVEFEWLRQFWFQGNRYR+CTDWWCQPMAQLEALWKKMEGV
Sbjct 361 PAVLKQGEEIHNEVEFEWLRQFWFQGNRYRRCTDWWCQPMAQLEALWKKMEGV------- 413



Range 1: 1 to 505








TNAVLHEVKREGLP+EQRNEILTAILASLTARQNLRREWHARCQSR
Sbjct 414 --------------TNAVLHEVKREGLPMEQRNEILTAILASLTARQNLRREWHARCQSR 459


Range 1: 1 to 505










Range 1: 1 to 505







TNAVLHEVK EGLP+EQRNEILTAILASLTARQNLRREWHARCQSR
Sbjct 414 --------------TNAVLHEVKGEGLPMEQRNEILTAILASLTARQNLRREWHARCQSR 459


Range 1: 48 to 552










Range 1: 1 to 515







Query 411 EGVISVELYKELGLMSPRLIRHKATNAVLHEVKREGLPVEQRNEILTAILASLTARQNLR 470

Sbjct 421 EGV---------------------TNAVLHEVKREGLPVEQRNEILTAILASLTARQNLR 459

Range 1: 1 to 515








EGV TNAVLHEVKREGLP+EQRNEILTAILASLTARQNLR
Sbjct 421 EGV---------------------TNAVLHEVKREGLPMEQRNEILTAILASLTARQNLR 459


Range 1: 1 to 505








TNAVLHEVKREGLPVEQRNEILTAILASLTAR NLRREWHARCQSR
Sbjct 414 --------------TNAVLHEVKREGLPVEQRNEILTAILASLTARHNLRREWHARCQSR 459

IARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRG LLEAKP
Sbjct 460 IARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRGHLLEAKP 505

Range 1: 1 to 505






PAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKME V
Sbjct 361 PAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEAV------- 413


IARTLPADQKPECRPYWEKDD SMPLPFDLTDIVSELRGQLLEAKP
Sbjct 460 IARTLPADQKPECRPYWEKDDVSMPLPFDLTDIVSELRGQLLEAKP 505

Range 1: 1 to 515








EGV TNAVLHEVK EGLP+EQRNEILTAILASLTARQNLR
Sbjct 421 EGV---------------------TNAVLHEVKGEGLPMEQRNEILTAILASLTARQNLR 459


Range 1: 48 to 562









FTO [Pongo abelii]
Range 1: 1 to 505










Range 1: 37 to 541








Sbjct 496 IARTLPADQKPECRPYWEKDDISMPLPFDLTDIVSELRGQLLEAKP 541

fascicularis]
atys]
Range 1: 37 to 541










Range 1: 1 to 505










tephrosceles]
Range 1: 37 to 541










Range 1: 1 to 515








EGV TNAVLHEVKREGLPVEQRNEILTAILASLTAR NLR
Sbjct 421 EGV---------------------TNAVLHEVKREGLPVEQRNEILTAILASLTARHNLR 459

REWHARCQSRIARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRG LLEAKP
Sbjct 460 REWHARCQSRIARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRGHLLEAKP 515

francoisi]
Range 1: 37 to 541










Range 1: 1 to 497








Query 481 IARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELR 518

IARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELR
Sbjct 460 IARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELR 497

Range 1: 37 to 541









IARTLPADQKPECRPYWEKDD SMPLPFDLTD+VSELRGQLLEAKP
Sbjct 496 IARTLPADQKPECRPYWEKDDVSMPLPFDLTDLVSELRGQLLEAKP 541

Range 1: 1 to 500








Query 481 IARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRGQL 521
IARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELR ++
Sbjct 460 IARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRDRV 500

sabaeus]
Range 1: 37 to 541








TNAVL EVKREGLPVEQRNEILTAILASLTARQNLRREWHARCQSR
Sbjct 450 --------------TNAVLREVKREGLPVEQRNEILTAILASLTARQNLRREWHARCQSR 495


Range 1: 1 to 515








E V TNAVLHEVKREGLPVEQRNEILTAILASLTARQNLR
Sbjct 421 EAV---------------------TNAVLHEVKREGLPVEQRNEILTAILASLTARQNLR 459

REWHARCQSRIARTLPADQKPECRPYWEKDD SMPLPFDLTDIVSELRGQLLEAKP
Sbjct 460 REWHARCQSRIARTLPADQKPECRPYWEKDDVSMPLPFDLTDIVSELRGQLLEAKP 515

palliatus]
Range 1: 37 to 541










Range 1: 37 to 541







PAVLKQGEEI +VEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGV
Sbjct 397 PAVLKQGEEIXXQVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGV------- 449



Range 1: 1 to 515









REWHARCQSRIARTLPADQKPECRPYWEKDD SMPLPFDLTDIVSELRGQLLEAKP
Sbjct 460 REWHARCQSRIARTLPADQKPECRPYWEKDDVSMPLPFDLTDIVSELRGQLLEAKP 515
Range 1: 1 to 497









IARTLPADQKPECRPYWEKDD SMPLPFDLTDIVSELR
Sbjct 460 IARTLPADQKPECRPYWEKDDVSMPLPFDLTDIVSELR 497

Range 1: 1 to 500









IARTLPADQKPECRPYWEKDD SMPLPFDLTDIVSELR ++
Sbjct 460 IARTLPADQKPECRPYWEKDDVSMPLPFDLTDIVSELRDRV 500

Range 1: 1 to 505






PAVLKQGEEIHNEVEFEWLRQFWFQG+RY+KCTDWWCQPMAQLE LWKKMEGV
Sbjct 361 PAVLKQGEEIHNEVEFEWLRQFWFQGSRYKKCTDWWCQPMAQLEELWKKMEGV------- 413


IARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRGQLLEA+P
Sbjct 460 IARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRGQLLEARP 505

Range 1: 24 to 528







PAVLKQGEEIHNEVEFEWLRQFWFQGNRY+KCTDWWCQPMAQLE LWKKMEGV
Sbjct 384 PAVLKQGEEIHNEVEFEWLRQFWFQGNRYKKCTDWWCQPMAQLEELWKKMEGV------- 436



Range 1: 37 to 535








Query 481 IARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRGQ 520

IARTLPADQKPECRPYWEKDD SMPLPFDLTDIVSELR +
Sbjct 496 IARTLPADQKPECRPYWEKDDVSMPLPFDLTDIVSELRAE 535

Range 1: 37 to 534








Query 481 IARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRG 519

IARTLPADQKPECRPYWEKDD SMPLPFDLTDIVSELRG
Sbjct 496 IARTLPADQKPECRPYWEKDDVSMPLPFDLTDIVSELRG 534

fascicularis]
Range 1: 37 to 533








IARTLPADQKPECRPYWEKDD SMPLPFDLTDIVSELR
Sbjct 496 IARTLPADQKPECRPYWEKDDVSMPLPFDLTDIVSELR 533

boliviensis]
Range 1: 15 to 519






PAVLKQGEEIHNEVEFEWLRQFWFQGNRY+KCTDWWCQPMAQLE +WKKMEGV
Sbjct 375 PAVLKQGEEIHNEVEFEWLRQFWFQGNRYKKCTDWWCQPMAQLEEMWKKMEGV------- 427


IARTLPADQKPECRPYWEKDDASM LPFDLTDIVSELRGQLLE +P
Sbjct 474 IARTLPADQKPECRPYWEKDDASMHLPFDLTDIVSELRGQLLEGRP 519

Range 1: 13 to 512






Query 366 QGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVISVELYKELGLM 425

QGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGV
Sbjct 373 QGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGV------------ 420
Query 426 SPRLIRHKATNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHARCQSRIARTL 485
TNAVLHEVKREGLP+EQRNEILTAILASLTARQNLRREWHARCQSRIARTL
Sbjct 421 ---------TNAVLHEVKREGLPMEQRNEILTAILASLTARQNLRREWHARCQSRIARTL 471
Query 486 PADQKPECRPYWEKDDASMPLPFDLTDIVSELRGQLLEAKP 526

PADQKPECRPYWEKDDASMPLPFDLTDIVSELRGQLLEAKP
Sbjct 472 PADQKPECRPYWEKDDASMPLPFDLTDIVSELRGQLLEAKP 512

Range 1: 24 to 528










Range 1: 24 to 528








IARTLPADQKPECRPYWEKDDASMPLPFDLTD+VSELRGQLLEA+P
Sbjct 483 IARTLPADQKPECRPYWEKDDASMPLPFDLTDVVSELRGQLLEARP 528

Range 1: 1 to 505






PAVLKQGEEIHNEVEFEWLR FWFQGNRYRKCTDWWCQP+A LEALWKKMEGV
Sbjct 361 PAVLKQGEEIHNEVEFEWLRXFWFQGNRYRKCTDWWCQPVAHLEALWKKMEGV------- 413

TNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHARCQS+
Sbjct 414 --------------TNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHARCQSQ 459

IARTLPADQKPECRPYWEKDD SMPLPFDLTDIVSELRGQLL+AKP
Sbjct 460 IARTLPADQKPECRPYWEKDDISMPLPFDLTDIVSELRGQLLKAKP 505

Range 1: 1 to 505






PAVLKQGEEIHNEVEFEWLRQFWFQGN YRKCTDWWCQP+AQLEALWKKMEGV
Sbjct 361 PAVLKQGEEIHNEVEFEWLRQFWFQGNGYRKCTDWWCQPVAQLEALWKKMEGV------- 413

TNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHARCQS+
Sbjct 414 --------------TNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHARCQSQ 459

IARTLPADQKPECRPYWEKDD SMPLPFDLTDIVSELRGQLL+AKP
Sbjct 460 IARTLPADQKPECRPYWEKDDISMPLPFDLTDIVSELRGQLLKAKP 505

atys]
Range 1: 10 to 499






Query 376 FEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVISVELYKELGLMSPRLIRHKAT 435

FEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGV T
Sbjct 370 FEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGV---------------------T 408
Query 436 NAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHARCQSRIARTLPADQKPECRP 495

NAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHARCQSRIARTLPADQKPECRP
Sbjct 409 NAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHARCQSRIARTLPADQKPECRP 468
Query 496 YWEKDDASMPLPFDLTDIVSELRGQLLEAKP 526
YWEKDD SMPLPFDLTDIVSELRGQLLEAKP
Sbjct 469 YWEKDDVSMPLPFDLTDIVSELRGQLLEAKP 499

Range 1: 24 to 559







Query 390 RKCTDWWCQPMAQLEALWKKMEGVISVELYKELGLMSPRLIRHKATNAVLHEVKREGLPV 449

+KCTDWWCQPMAQLE LWKKMEGV TNAVLHEVKREGLPV
Sbjct 444 KKCTDWWCQPMAQLEELWKKMEGV---------------------TNAVLHEVKREGLPV 482
Query 450 EQRNEILTAILASLTARQNLRREWHARCQSRIARTLPADQKPECRPYWEKDDASMPLPFD 509

EQRNEILTAILASLTARQNLRREWHARCQSRIARTLPADQKPECRPYWEKDDASMPLPFD
Sbjct 483 EQRNEILTAILASLTARQNLRREWHARCQSRIARTLPADQKPECRPYWEKDDASMPLPFD 542
Query 510 LTDIVSELRGQLLEAKP 526

LTDIVSELRGQLLEA+P
Sbjct 543 LTDIVSELRGQLLEARP 559

sabaeus]
Range 1: 6 to 496






Query 375 EFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVISVELYKELGLMSPRLIRHKA 434

EFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGV
Sbjct 366 EFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGV--------------------- 404
Query 435 TNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHARCQSRIARTLPADQKPECR 494

TNAVL EVKREGLPVEQRNEILTAILASLTARQNLRREWHARCQSRIARTLPADQKPECR
Sbjct 405 TNAVLREVKREGLPVEQRNEILTAILASLTARQNLRREWHARCQSRIARTLPADQKPECR 464
Query 495 PYWEKDDASMPLPFDLTDIVSELRGQLLEAKP 526

PYWEKDD SMPLPFDLTDIVSELRGQLLEAKP
Sbjct 465 PYWEKDDVSMPLPFDLTDIVSELRGQLLEAKP 496

atys]
Range 1: 3 to 492








YWEKDD SMPLPFDLTDIVSELRGQLLEAKP
Sbjct 462 YWEKDDVSMPLPFDLTDIVSELRGQLLEAKP 492

Range 1: 13 to 512






Query 366 QGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVISVELYKELGLM 425

QGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKME V
Sbjct 373 QGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEAV------------ 420
Query 426 SPRLIRHKATNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHARCQSRIARTL 485

TNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHARCQSRIARTL
Sbjct 421 ---------TNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHARCQSRIARTL 471

PADQKPECRPYWEKDD SMPLPFDLTDIVSELRGQLLEAKP
Sbjct 472 PADQKPECRPYWEKDDVSMPLPFDLTDIVSELRGQLLEAKP 512

Range 1: 24 to 528







PAVLKQGEEIHNEVEFEWLRQFWFQGNRY+KCTDWWCQPM QLE LWKKMEGV
Sbjct 384 PAVLKQGEEIHNEVEFEWLRQFWFQGNRYKKCTDWWCQPMTQLEELWKKMEGV------- 436

TNAVL EVKREGLPVEQRNEILTAILASLT RQNLRREWHARCQ R
Sbjct 437 --------------TNAVLREVKREGLPVEQRNEILTAILASLTTRQNLRREWHARCQCR 482

IARTLP DQKPECRPYWEK+D SMPLPFDLTD+VSELRGQLLEAKP
Sbjct 483 IARTLPVDQKPECRPYWEKEDPSMPLPFDLTDVVSELRGQLLEAKP 528

Range 1: 16 to 506








TNAVLHEVKREGLP+EQRNEILTAILASLTARQNLRREWHARCQSRIARTLPADQKPECR
Sbjct 415 TNAVLHEVKREGLPMEQRNEILTAILASLTARQNLRREWHARCQSRIARTLPADQKPECR 474

PYWEKDD SMPLPFDLTD+VSELRGQLLEAKP
Sbjct 475 PYWEKDDVSMPLPFDLTDLVSELRGQLLEAKP 506

coquereli]
Range 1: 1 to 505






PAVLKQGEEIHNEVEFEWLRQFWFQGNRY+KCTDWWCQPM QLE WKKMEGV
Sbjct 361 PAVLKQGEEIHNEVEFEWLRQFWFQGNRYKKCTDWWCQPMTQLEERWKKMEGV------- 413


IARTLP DQKPECRPYWEK+D SMPLPFDLTDIVS+LRGQLLEAKP
Sbjct 460 IARTLPVDQKPECRPYWEKEDPSMPLPFDLTDIVSDLRGQLLEAKP 505

Range 1: 3 to 478






RKCTDWWCQPMAQLEALWKKMEGV TNAVLHEVKREGLPV
Sbjct 363 RKCTDWWCQPMAQLEALWKKMEGV---------------------TNAVLHEVKREGLPV 401


LTDIVSELRGQLLEAKP
Sbjct 462 LTDIVSELRGQLLEAKP 478

FTO [Homo sapiens]
FTO [Homo sapiens]
FTO [Homo sapiens]
FTO [Homo sapiens]
FTO [Homo sapiens]
FTO [Homo sapiens]
FTO [Homo sapiens]
FTO [Homo sapiens]
Fto [Homo sapiens]
Range 1: 20 to 495









LTDIVSELRGQLLEAKP

Range 1: 2 to 485








Query 496 YWEKDDASMPLPFDLTDIVSELRGQ 520

YWEKDD SMPLPFDLTDIVSELR +
Sbjct 461 YWEKDDVSMPLPFDLTDIVSELRAE 485

Range 1: 3 to 476








Query 510 LTDIVSELRGQLLEA 524

LTDIVSELRGQLLEA
Sbjct 462 LTDIVSELRGQLLEA 476

fascicularis]
Range 1: 3 to 484








Query 496 YWEKDDASMPLPFDLTDIVSELR 518

YWEKDD SMPLPFDLTDIVSELR
Sbjct 462 YWEKDDVSMPLPFDLTDIVSELR 484
Range 1: 16 to 499








TNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHARCQSRIARTLPADQKPECR
Sbjct 415 TNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHARCQSRIARTLPADQKPECR 474
Query 495 PYWEKDDASMPLPFDLTDIVSELRG 519

PYWEKDD SMPLPFDLTDIVSELRG
Sbjct 475 PYWEKDDVSMPLPFDLTDIVSELRG 499

Range 1: 4 to 479









LTDIVSELRGQLLEAKP

Range 1: 4 to 476








Query 510 LTDIVSELRGQLLE 523

LTDIVSELRGQLLE
Sbjct 463 LTDIVSELRGQLLE 476

Range 1: 20 to 492








Query 510 LTDIVSELRGQLLE 523
LTDIVSELRGQLLE
Sbjct 479 LTDIVSELRGQLLE 492

Range 1: 1 to 479










coquereli]
Range 1: 1 to 498







PAVLKQGEEIHNEVEFEWLRQFWFQGNRY+KCTDWWCQPM QLE WKKMEGV
Sbjct 361 PAVLKQGEEIHNEVEFEWLRQFWFQGNRYKKCTDWWCQPMTQLEERWKKMEGV------- 413

Query 481 IARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRG 519

IARTLP DQKPECRPYWEK+D SMPLPFDLTDIVS+LRG
Sbjct 460 IARTLPVDQKPECRPYWEKEDPSMPLPFDLTDIVSDLRG 498
>alpha-ketoglutarate-dependent dioxygenase FTO [Puma concolor]

Range 1: 16 to 526

KKLRLLEELEDTWLPYLTPKDDEFYQQWQLKYPKLILREA SV EELHKEVQEAFLTLHK
Sbjct 16 KKLRLLEELEDTWLPYLTPKDDEFYQQWQLKYPKLILREAGSVPEELHKEVQEAFLTLHK 75

HGC FRDLVRIQGKDLLTPVSRILIGNPGCTYKYLNTRLFTVPWPVKG++ ++ EAEIAA
Sbjct 76 HGCFFRDLVRIQGKDLLTPVSRILIGNPGCTYKYLNTRLFTVPWPVKGASTRYEEAEIAA 135

AC+TFL+LNDYLQIETIQALEELA KEK+N DAVP+C+ DFPRVGMGS ++GQDEVDIK
Sbjct 136 ACQTFLRLNDYLQIETIQALEELACKEKSNIDAVPVCIGPDFPRVGMGS-FDGQDEVDIK 194

+RAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLV+RSAVAVYSYSCEGPEE
Sbjct 195 NRAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLVERSAVAVYSYSCEGPEE 254

ESEDD LEGRDPD WHVGFKISWDIETPGLAIPLHQGDCYFMLDDLNATHQHCVLAG
Sbjct 255 ESEDDPQLEGRDPDTWHVGFKISWDIETPGLAIPLHQGDCYFMLDDLNATHQHCVLAGLP 314

PRFSSTHRVAECSTGTLDYILQRCQ+ALQNV D D D SLKSFEPAVLKQGEEIHNEV
Sbjct 315 PRFSSTHRVAECSTGTLDYILQRCQVALQNVRDGADGGDASLKSFEPAVLKQGEEIHNEV 374

EFEWLRQFWFQGNRYRKC+DWWCQPMAQLE LWKKMEGVISV+ YK+ GL+SPRLI+HKA
Sbjct 375 EFEWLRQFWFQGNRYRKCSDWWCQPMAQLEELWKKMEGVISVKFYKKPGLLSPRLIKHKA 434

TNAVL EV+REG+PVEQRNEILTA+LASL RQNLRREWHARCQSRIARTLP DQKPECR
Sbjct 435 TNAVLREVRREGVPVEQRNEILTAVLASLATRQNLRREWHARCQSRIARTLPVDQKPECR 494

PYWEKDD SMPLPFDLTD+VSELRG LLEAKP
Sbjct 495 PYWEKDDPSMPLPFDLTDVVSELRGLLLEAKP 526

Range 1: 1 to 504






PAVLKQGEEIHNEVEFEWLRQFWFQGNRY+KCTDWWCQPM QLE LWK+MEGV
Sbjct 360 PAVLKQGEEIHNEVEFEWLRQFWFQGNRYKKCTDWWCQPMTQLEELWKRMEGV------- 412

TNAVLHEVKREGLPVEQRNEILTA+L LT RQNLRREWHARCQ R
Sbjct 413 --------------TNAVLHEVKREGLPVEQRNEILTAVLPLLTTRQNLRREWHARCQCR 458

IARTLP DQKPECRPYWEKDD SMPLPFDLTDIVSELR QLLEAKP
Sbjct 459 IARTLPVDQKPECRPYWEKDDPSMPLPFDLTDIVSELRSQLLEAKP 504

Range 1: 1 to 504







PA+LKQGEEIHNEVEFEWLRQFWFQG+RYRKCTDWWC+PM++LE LWKKME V
Sbjct 360 PAILKQGEEIHNEVEFEWLRQFWFQGSRYRKCTDWWCEPMSKLEGLWKKMESV------- 412

TNAVL EVKREGLPVEQRNEILTAILA LT RQNLRREWHARCQ R
Sbjct 413 --------------TNAVLREVKREGLPVEQRNEILTAILAPLTTRQNLRREWHARCQCR 458

IARTLP DQKP+CRPYWEKDDASMPLPFDLTDIVSELR QLLEAKP
Sbjct 459 IARTLPVDQKPDCRPYWEKDDASMPLPFDLTDIVSELRAQLLEAKP 504
Range 1: 1 to 504










Range 1: 1 to 504









Range 1: 1 to 504





AVAVY+YSCEGP++ES+DDS+LEGRDPDIWHVGFKISWDIETPGLAIPLHQGDCYFMLDD
Sbjct 240 AVAVYNYSCEGPDDESDDDSNLEGRDPDIWHVGFKISWDIETPGLAIPLHQGDCYFMLDD 299

LNATHQHCVLAGSQPRFSSTHRVAECS GTLDYILQRCQLALQNV DD D V+LKSFE
Sbjct 300 LNATHQHCVLAGSQPRFSSTHRVAECSMGTLDYILQRCQLALQNVRDDADGTAVTLKSFE 359

PAVLKQGEEIHNEVEFEWLRQ+WFQGNRY+KCTDWWC+PM QLE LWKKME V
Sbjct 360 PAVLKQGEEIHNEVEFEWLRQYWFQGNRYKKCTDWWCEPMTQLEGLWKKMEDV------- 412

TNAVLHEVKREGLPVEQRNEILTAILA LT RQNLRREWHARCQ R
Sbjct 413 --------------TNAVLHEVKREGLPVEQRNEILTAILAPLTTRQNLRREWHARCQCR 458

IARTLP DQKP+CRPYWEKDD SMPLPFDLT++VSELRG LLEAKP
Sbjct 459 IARTLPVDQKPDCRPYWEKDDPSMPLPFDLTELVSELRGLLLEAKP 504

Range 1: 1 to 506




Query 241 AVAVYSY-SCEGPEEESEDDSHLEGRDPDIWHVGFKISWDIETPGLAIPLHQGDCYFMLD 299

AVAVY+Y E EEESEDDSHLEGRDPDIWHVGFKISWDIETPGLAIPLHQGDCYFMLD

Query 360 EPAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVISVELY 419

EPAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPM LE LWKKMEGV
Sbjct 361 EPAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMTHLEGLWKKMEGV------ 414
Query 420 KELGLMSPRLIRHKATNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHARCQS 479
TNAVLHEVKREGLPVEQRNEILTAILA LT RQNLRREWHARCQS
Sbjct 415 ---------------TNAVLHEVKREGLPVEQRNEILTAILALLTTRQNLRREWHARCQS 459
Query 480 RIARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRGQLLEAKP 526

RIARTLP DQKPECRPYWEKDD SMPLPFDLTDIVSELRG LLEAKP
Sbjct 460 RIARTLPGDQKPECRPYWEKDDPSMPLPFDLTDIVSELRGLLLEAKP 506

Range 1: 1 to 504










FTO [Homo sapiens]
FTO [Homo sapiens]
Range 1: 1 to 463



Query 217 EEPYFGMGKMAVSWHHDENLVDRSAVAVYSYSCEGPEEESEDDSHLEGRDPDIWHVGFKI 276

EEPYFGMGKMAVSWHHDENLVDRSAVAVYSYSCEGPEEESEDDSHLEGRDPDIWHVGFKI
Sbjct 181 EEPYFGMGKMAVSWHHDENLVDRSAVAVYSYSCEGPEEESEDDSHLEGRDPDIWHVGFKI 240
Query 277 SWDIETPGLAIPLHQGDCYFMLDDLNATHQHCVLAGSQPRFSSTHRVAECSTGTLDYILQ 336

SWDIETPGLAIPLHQGDCYFMLDDLNATH+HCVLAGSQPRFSSTHRVAECSTGTLDYILQ
Sbjct 241 SWDIETPGLAIPLHQGDCYFMLDDLNATHKHCVLAGSQPRFSSTHRVAECSTGTLDYILQ 300
Query 337 RCQLALQNVCDDVDNDDVSLKSFEPAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWW 396

RCQLALQNVCDDVDNDDVSLKSFEPAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWW
Sbjct 301 RCQLALQNVCDDVDNDDVSLKSFEPAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWW 360
Query 397 CQPMAQLEALWKKMEGVISVELYKELGLMSPRLIRHKATNAVLHEVKREGLPVEQRNEIL 456

CQPMAQLEALWKKMEGV TNAVLHEVKREGLPVEQRNEIL
Sbjct 361 CQPMAQLEALWKKMEGV---------------------TNAVLHEVKREGLPVEQRNEIL 399

TAILASLTARQNLRREWHARCQSRIARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSE
Sbjct 400 TAILASLTARQNLRREWHARCQSRIARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSE 459
Query 517 LRGQ 520

LRGQ
Sbjct 460 LRGQ 463

Range 1: 1 to 479










Range 1: 1 to 505







Sbjct 361 PAVLKQGEEIHNEVEFEWLRQFWFQGNRYKKCTDWWCQPMTQLEELWKKMEGV------- 413

TNAVLHEV+REG+PVEQRNEILTAILASLT RQNLRREWHARCQ R
Sbjct 414 --------------TNAVLHEVRREGVPVEQRNEILTAILASLTTRQNLRREWHARCQCR 459

IARTLP DQKPECRPYWEKDD SMPLPFDLTDI+SELRG LLEAKP
Sbjct 460 IARTLPVDQKPECRPYWEKDDPSMPLPFDLTDIISELRGLLLEAKP 505

Range 1: 1 to 505







PAVLKQGEEIHNEVEFEWLRQFWFQGNRY+KCTDWWCQPM QLE LWKKME V
Sbjct 361 PAVLKQGEEIHNEVEFEWLRQFWFQGNRYKKCTDWWCQPMTQLEELWKKMEAV------- 413
TNAVLHEV+REG+PVEQRNEILTAILASLT RQNLRREWHARCQ R
Sbjct 414 --------------TNAVLHEVRREGVPVEQRNEILTAILASLTTRQNLRREWHARCQCR 459


Range 1: 46 to 549







P VLKQGEEIHNEVEFEWLRQ+WFQGNRYRKCTDWWCQPM QLE LWKKMEGV
Sbjct 405 PVVLKQGEEIHNEVEFEWLRQYWFQGNRYRKCTDWWCQPMTQLEGLWKKMEGV------- 457

TNAVLHEV+REG+PVEQRNEILTAILA LT RQNLRREWHARCQSR
Sbjct 458 --------------TNAVLHEVRREGVPVEQRNEILTAILALLTTRQNLRREWHARCQSR 503

IARTLP DQKPECRPYWEKDD SMPLPFDLTDIVSELRG LLEAKP
Sbjct 504 IARTLPVDQKPECRPYWEKDDPSMPLPFDLTDIVSELRGLLLEAKP 549
Range 1: 46 to 549









IARTLP DQKPECRPYWEKDD SMPLPFDLTDIVSELRG LLEAKP
Sbjct 504 IARTLPVDQKPECRPYWEKDDPSMPLPFDLTDIVSELRGLLLEAKP 549

Range 1: 15 to 519







P VLK GEEIHNEVEFEWLRQFWFQGNRY++CTDWWCQPM QLE LWKKMEG+
Sbjct 375 PVVLKHGEEIHNEVEFEWLRQFWFQGNRYKRCTDWWCQPMTQLEELWKKMEGL------- 427

TNAVL EV+REG PVEQRNEILTAILA+LTARQNLRREWHARCQSR
Sbjct 428 --------------TNAVLREVRREGTPVEQRNEILTAILATLTARQNLRREWHARCQSR 473

IARTLPADQKPECRPYWEKDD SMPLPFDLTDI+SELR LLEAKP
Sbjct 474 IARTLPADQKPECRPYWEKDDPSMPLPFDLTDIISELRSLLLEAKP 519

Range 1: 1 to 504







PAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKC+DWWCQPMAQLE LWKKMEGV
Sbjct 360 PAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCSDWWCQPMAQLEELWKKMEGV------- 412

TNAVL EV+REG+PVEQRNEILTAILASLT RQNLRREWHARCQSR
Sbjct 413 --------------TNAVLREVRREGVPVEQRNEILTAILASLTTRQNLRREWHARCQSR 458

IARTLP DQKPECRPYWEKDD SMPLPFDLTD+VSELRG LLEAKP
Sbjct 459 IARTLPVDQKPECRPYWEKDDPSMPLPFDLTDVVSELRGLLLEAKP 504

Range 1: 1 to 505







PAVLKQGEEIHNEVEFEWLRQFWFQGNRY+KCTDWWCQPM QLE LWKKME V
Sbjct 361 PAVLKQGEEIHNEVEFEWLRQFWFQGNRYKKCTDWWCQPMTQLEELWKKMEAV------- 413

TNAVLHEV++EG+PVEQRNEILTAILASLT RQNLRREWHARCQ R
Sbjct 414 --------------TNAVLHEVRQEGVPVEQRNEILTAILASLTTRQNLRREWHARCQCR 459

Range 1: 1 to 505







PAVLKQGEEIHNEVEFEWLRQFWFQGNRY+KCT+WWCQPM QLE LWKKMEGV
Sbjct 361 PAVLKQGEEIHNEVEFEWLRQFWFQGNRYKKCTNWWCQPMTQLEELWKKMEGV------- 413

TNAVLHEV+REG PVEQRN+ILTAILA LT RQNLRREWHARCQ R
Sbjct 414 --------------TNAVLHEVRREGAPVEQRNKILTAILAVLTTRQNLRREWHARCQCR 459

IAR+LPADQKPECRPYWEKDD SMPLPF+LTDIVSELRG LLEAKP
Sbjct 460 IARSLPADQKPECRPYWEKDDPSMPLPFELTDIVSELRGLLLEAKP 505

Range 1: 1 to 504










Range 1: 1 to 504







TNAVLHEV+REG+PVEQRNEILTAILA LT+RQNLRREWHARCQSR
Sbjct 413 --------------TNAVLHEVRREGVPVEQRNEILTAILALLTSRQNLRREWHARCQSR 458


Range 1: 1 to 505






PAVLKQGEEIHNEVEFEWLRQFWFQGNRY+KCTDWW QPM QLE LWKKMEGV
Sbjct 361 PAVLKQGEEIHNEVEFEWLRQFWFQGNRYKKCTDWWWQPMTQLEELWKKMEGV------- 413

TNAVL EV+REG PVEQRN+ILTAILA LT RQNLRREWHARCQ R
Sbjct 414 --------------TNAVLQEVRREGAPVEQRNKILTAILAVLTTRQNLRREWHARCQCR 459

IAR+LPADQKPECRPYWEKDD SMPLPFDLTDIVSELRG LLEAKP
Sbjct 460 IARSLPADQKPECRPYWEKDDPSMPLPFDLTDIVSELRGLLLEAKP 505

Range 1: 15 to 519







Sbjct 375 PVVLKHGEEIHNEVEFEWLRQFWFQGNRYKRCTDWWCQPMTQLEELWKKMEGL------- 427

TNAVL EV+REG PVEQRNEILTAILA+LTARQNLRREWHARCQSR
Sbjct 428 --------------TNAVLREVRREGTPVEQRNEILTAILATLTARQNLRREWHARCQSR 473
IARTLPADQKPECRPYWEKDD SMPLPFDLTDI+SELR LLEAKP
Sbjct 474 IARTLPADQKPECRPYWEKDDPSMPLPFDLTDIISELRSLLLEAKP 519

Range 1: 1 to 504







P VLKQGEEIHNEVEFEWLRQFWFQGNRYRKC+DWWCQPMAQLE LWKKMEGV
Sbjct 360 PVVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCSDWWCQPMAQLEELWKKMEGV------- 412

TNAVL EV+REG+PVEQRNEILTAILA LT+RQNLRREWHARCQSR
Sbjct 413 --------------TNAVLREVRREGVPVEQRNEILTAILALLTSRQNLRREWHARCQSR 458


Range 1: 46 to 549







PAVLKQGEEIHNEVEFEWLRQ+WFQGNRYRKCTDWWCQPM QLE LWKKMEGV
Sbjct 405 PAVLKQGEEIHNEVEFEWLRQYWFQGNRYRKCTDWWCQPMTQLEGLWKKMEGV------- 457


IARTLP DQKPECRPYWEKDD SMPLPFDLTDIVSELR LLE KP
Sbjct 504 IARTLPVDQKPECRPYWEKDDPSMPLPFDLTDIVSELRSLLLEGKP 549

Range 1: 65 to 568









Range 1: 1 to 504







P+VLKQGEEIHNEVEFEWLRQFWFQGNRYRKC+DWWCQPMAQLE LWKKMEGV
Sbjct 360 PSVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCSDWWCQPMAQLEELWKKMEGV------- 412


IARTLP DQKPECRPYWEKDD SMPLPFDLTD VSELRG LLEAKP
Sbjct 459 IARTLPVDQKPECRPYWEKDDPSMPLPFDLTDAVSELRGLLLEAKP 504

Range 1: 1 to 504









Range 1: 1 to 499









IARTLP DQKPECRPYWEKDD SMPLPFDLTDIVSELRG+
Sbjct 459 IARTLPVDQKPECRPYWEKDDPSMPLPFDLTDIVSELRGEF 499

Range 1: 46 to 549








TNAVLHEV+REG+PVEQR EILTAILA LT RQNLRREWHARCQSR
Sbjct 458 --------------TNAVLHEVRREGVPVEQRTEILTAILALLTTRQNLRREWHARCQSR 503


Range 1: 46 to 549









Range 1: 1 to 458







Query 421 ELGLMSPRLIRHKATNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHARCQS 479

TNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHAR +
Sbjct 414 --------------TNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHARATT 458

Range 1: 1 to 504









>FTo [Sus scrofa]

>FTO [Sus scrofa]
scrofa]
Range 1: 1 to 505







PAVLKQGEEIHNEVEFEWLRQFWFQGNRY+KCTDWWCQPM QLE LWKKMEG
Sbjct 361 PAVLKQGEEIHNEVEFEWLRQFWFQGNRYKKCTDWWCQPMTQLEELWKKMEG-------- 412

AT+AVL EV+REG PVEQ ++ILTAILA LT RQNLRREWHARCQSR
Sbjct 413 -------------ATHAVLREVRREGAPVEQSSDILTAILAVLTTRQNLRREWHARCQSR 459

IARTLP DQKPECRPYWEKDD SMPLPFDLTD V+ELRG LLEAKP
Sbjct 460 IARTLPVDQKPECRPYWEKDDPSMPLPFDLTDTVAELRGLLLEAKP 505

Range 1: 1 to 457






Query 421 ELGLMSPRLIRHKATNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHARCQ 478

TNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHAR +
Sbjct 414 --------------TNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHARVE 457

Range 1: 1 to 505








>alpha-ketoglutarate-dependent dioxygenase FTO isoform X1 [Trichechus manatus

latirostris]
Range 1: 1 to 505

MKRT TAEEREREAKKLRLLEELED WLPYLTPKDDEFYQQW LKYPKLILREA +V EE
Sbjct 1 MKRTQTAEEREREAKKLRLLEELEDAWLPYLTPKDDEFYQQWHLKYPKLILREADNVPEE 60


KGS IK+TE EI AAC+TFLKLNDYLQ ETIQALEEL +KEK++ DA+P+ ++ DFPR+G
Sbjct 121 KGSTIKYTEDEIGAACQTFLKLNDYLQTETIQALEELTSKEKSSGDALPVYIAPDFPRIG 180

MGSS++GQDE D+KSRAAYNVTLLNFMDPQKM YLKEEPYFGMGKMAVSWHHDENLV+RS
Sbjct 181 MGSSFDGQDEEDVKSRAAYNVTLLNFMDPQKMSYLKEEPYFGMGKMAVSWHHDENLVERS 240

AVAVY+YSCEGPEEESEDD LEGRDPD WHVGFKISWDIETPGLAIPLHQGDCYFMLDD
Sbjct 241 AVAVYNYSCEGPEEESEDDPDLEGRDPDTWHVGFKISWDIETPGLAIPLHQGDCYFMLDD 300

LNATHQHCVLAGSQPRFSSTHRVAECSTGTLDYILQRCQLALQN+ D+VD+ DVSLKS E
Sbjct 301 LNATHQHCVLAGSQPRFSSTHRVAECSTGTLDYILQRCQLALQNLRDEVDDGDVSLKSLE 360

PA+LKQGEEIHNEVEFEWLRQ+WFQGNRY+KCTDWWCQPM QLE LWKKMEGV
Sbjct 361 PAILKQGEEIHNEVEFEWLRQYWFQGNRYKKCTDWWCQPMTQLEGLWKKMEGV------- 413

TNAVL EV++EGLPVEQRNEILTAILA LT RQNLRREWHARCQSR
Sbjct 414 --------------TNAVLREVRKEGLPVEQRNEILTAILALLTTRQNLRREWHARCQSR 459
IARTL DQKPEC+PYWEKDD SMPLPFDLTDIVSELRGQLL+AKP
Sbjct 460 IARTLSVDQKPECQPYWEKDDPSMPLPFDLTDIVSELRGQLLQAKP 505

Range 1: 1 to 454







Query 421 ELGLMSPRLIRHKATNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHA 475

TNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHA
Sbjct 414 --------------TNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHA 454

Range 1: 1 to 455







Query 421 ELGLMSPRLIRHKATNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHAR 476

TNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHAR
Sbjct 414 --------------TNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHAR 455
>fat mass and obesity-associated protein [Sus scrofa]

Sequence ID: ACY82516.1 Length: 505
Range 1: 1 to 505






LNATHQHCVLAG PRFSST RVAECSTGTLDYILQRCQLALQNV D+ D+ +VSLKS E
Sbjct 301 LNATHQHCVLAGLPPRFSSTRRVAECSTGTLDYILQRCQLALQNVRDEADSGEVSLKSLE 360




Range 1: 1 to 504








TNAVL EV+REG+PVEQR EILTAILA LT RQNLRREWHARCQSR
Sbjct 413 --------------TNAVLREVRREGVPVEQRTEILTAILALLTTRQNLRREWHARCQSR 458


Max Total
Query E Per.
0.0 100.00 NP_001350825.1
0.0 97.60 XP_025225779.1
0.0 92.49 XP_032013254.1
0.0 89.18 NP_001350823.1
0.0 91.39 XP_003263101.1
0.0 91.50 PNJ62567.1
0.0 90.70 XP_032013253.1
0.0 91.50 NP_001126250.1
0.0 91.49 XP_007991498.1
0.0 91.30 XP_011760503.1
0.0 91.50 XP_010356591.2
0.0 89.64 XP_030652817.1
0.0 91.30 XP_005591989.1
0.0 91.30 XP_025225777.1
0.0 91.30 XP_023065721.2
0.0 91.30 XP_033074312.1
0.0 89.73 XP_009248996.1
0.0 90.71 XP_011827312.1
0.0 93.08 XP_024781684.1
0.0 90.82 PNJ62571.1
0.0 93.08 XP_510968.2
0.0 91.37 PNJ62570.1
0.0 89.53 XP_025225776.1
0.0 92.89 NP_001073901.1
0.0 92.69 BAG53322.1
0.0 89.92 XP_012303365.1
0.0 90.80 XP_031514106.1
0.0 89.72 XP_008984120.1
0.0 92.69 BAB21843.2
0.0 91.18 XP_014981634.1
0.0 91.16 XP_003916924.2
0.0 91.28 XP_009429081.1
0.0 91.28 XP_024781683.1
0.0 89.33 XP_032111506.1
0.0 89.13 XP_003937323.1
0.0 91.09 NP_001350820.1
0.0 88.54 XP_017385575.1
0.0 89.13 XP_033090538.1
0.0 92.42 PNI63969.1
0.0 92.97 PNI63967.1
0.0 88.32 XP_012628070.1
0.0 91.24 XP_007991499.1
0.0 88.74 XP_017719562.1
0.0 84.54 XP_035138572.1
0.0 91.04 XP_011921553.1
0.0 91.04 XP_011921571.1
0.0 90.85 XP_011760506.1
0.0 89.42 XP_009248997.1
0.0 87.72 XP_012508119.1
0.0 90.91 XP_011801988.1
0.0 90.52 XP_009194707.2
0.0 90.89 XP_015298227.1
0.0 90.72 XP_028697425.1
0.0 87.55 XP_012508120.1
0.0 91.02 XP_034796072.1
0.0 84.57 XP_012662320.1
0.0 84.95 XP_015343973.1
0.0 84.75 XP_027794874.1
0.0 84.55 XP_026248055.1
0.0 84.36 XP_005318239.1
0.0 87.18 XP_006148441.1
0.0 84.98 XP_006207900.1
0.0 84.39 XP_036690105.1
0.0 84.58 XP_006186034.1
0.0 84.58 XP_014683258.1
0.0 83.99 XP_007167659.1
0.0 84.98 XP_003998090.1
0.0 84.39 XP_005608321.1
0.0 84.39 XP_008511378.1
0.0 84.98 XP_019311473.1
0.0 84.78 XP_026900282.1
0.0 86.17 XP_025225781.1
0.0 84.78 XP_007096738.1
0.0 83.96 ACT65741.1
0.0 83.96 AEY68263.1
0.0 92.03 4ZS2_A
0.0 92.03 3LFM_A
fat mass and obesity-associated protein [Sus scrofa] 868 868 100%
0.0 83.76 ACY82516.1
0.0 100.00 PNI63979.1
0.0 100.00 XP_024306205.1
0.0 100.00 XP_016879145.1
0.0 100.00 PNI63976.1
0.0 100.00 XP_016879146.1
0.0 100.00 PNI63980.1
0.0 84.19 XP_030155469.1
0.0 100.00 PNI63975.1
0.0 98.34 NP_001350832.1
0.0 83.56 AFX62367.1
0.0 100.00 NP_001350917.1
0.0 100.00 XP_016785339.2
0.0 92.00 4QKN_A
0.0 83.76 XP_034881088.1
0.0 91.61 5DAB_A
0.0 91.98 5F8P_A
0.0 83.56 XP_006732653.1
0.0 82.77 XP_006043112.1
0.0 91.98 6AKW_A
0.0 83.37 XP_035937580.1
0.0 87.75 NP_001350826.1
0.0 83.56 XP_021560370.1
Alignments:
Range 1: 1 to 499





Query 361 PAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVMEFHSRC 420

PAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVMEFHSRC
Sbjct 361 PAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVMEFHSRC 420
Query 421 PGWSAMAQSWLTATSTSRVQVILLPQPPRCQSRIARTLPADQKPECRPYWEKDDASMPLP 480

PGWSAMAQSWLTATSTSRVQVILLPQPPRCQSRIARTLPADQKPECRPYWEKDDASMPLP
Sbjct 421 PGWSAMAQSWLTATSTSRVQVILLPQPPRCQSRIARTLPADQKPECRPYWEKDDASMPLP 480
Query 481 FDLTDIVSELRGQLLEAKP 499

FDLTDIVSELRGQLLEAKP
Sbjct 481 FDLTDIVSELRGQLLEAKP 499

Range 1: 1 to 499







PAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVMEFHS C
Sbjct 361 PAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVMEFHSCC 420
Query 421 PGWSAMAQSWLTATSTSRVQVILLPQPPRCQSRIARTLPADQKPECRPYWEKDDASMPLP 480

P WSAMAQSWLTATSTS VQVILLPQPP+CQSRIARTLPADQKPECRPYWEKDD SMPLP
Sbjct 421 PDWSAMAQSWLTATSTSWVQVILLPQPPKCQSRIARTLPADQKPECRPYWEKDDVSMPLP 480
Query 481 FDLTDIVSELRGQLLEAKP 499

FDLTDIVSELRGQLLEAKP
Sbjct 481 FDLTDIVSELRGQLLEAKP 499

Range 1: 48 to 552






Query 361 PAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVME--FHS 418

PAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGV H
Query 419 RCPGWSAMAQ-----SWLTATSTSRVQVILLPQPPRCQSRIARTLPADQKPECRPYWEKD 473

+ Q + + A+ T+R Q + RCQSRIARTLPADQKPECRPYWEKD
Sbjct 468 VKREGLPVEQRNEILTAILASLTAR-QNLRREWHARCQSRIARTLPADQKPECRPYWEKD 526

DASMPLPFDLTDIVSELRGQLLEAKP
Sbjct 527 DASMPLPFDLTDIVSELRGQLLEAKP 552

Range 1: 1 to 526






Query 361 PAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVMEFH--- 417

PAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGV+
Query 418 ---------SRCPGWSAMAQ----------------SWLTATSTSRVQVILLPQPPRCQS 452

R +A+ + + A+ T+R Q + RCQS
Sbjct 421 ELGLMSPRLIRHKATNAVLHEVKREGLPVEQRNEILTAILASLTAR-QNLRREWHARCQS 479
Query 453 RIARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRGQLLEAKP 499

RIARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRGQLLEAKP
Sbjct 480 RIARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRGQLLEAKP 526

Range 1: 1 to 505






Query 361 PAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGV------- 413

Query 414 -----MEFHSRCPGWSAMAQSWLTATSTSRVQVILLPQPPRCQSRIARTLPADQKPECRP 468

+ R +A+ S LTA R + RCQSRIARTLPADQKPECRP
Sbjct 421 VKREGLPVEQRNEILTAILAS-LTARHNLRRE-----WHARCQSRIARTLPADQKPECRP 474

YWEKDDASMPLPFDLTDIVSELRG LLEAKP
Sbjct 475 YWEKDDASMPLPFDLTDIVSELRGHLLEAKP 505

Range 1: 1 to 505







PAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKME V H


D SMPLPFDLTDIVSELRGQLLEAKP
Sbjct 480 DVSMPLPFDLTDIVSELRGQLLEAKP 505

Range 1: 48 to 562







Query 411 EGVME--FHSRCPGWSAMAQ-----SWLTATSTSRVQVILLPQPPRCQSRIARTLPADQK 463
EGV H + Q + + A+ T+R Q + RCQSRIARTLPADQK
Sbjct 468 EGVTNAVLHEVKREGLPVEQRNEILTAILASLTAR-QNLRREWHARCQSRIARTLPADQK 526
Query 464 PECRPYWEKDDASMPLPFDLTDIVSELRGQLLEAKP 499

PECRPYWEKDDASMPLPFDLTDIVSELRGQLLEAKP
Sbjct 527 PECRPYWEKDDASMPLPFDLTDIVSELRGQLLEAKP 562

FTO [Pongo abelii]
Range 1: 1 to 505









sabaeus]
Range 1: 37 to 541







PAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGV R
Sbjct 397 PAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVTNAVLRE 456
Query 421 PGWSAMA----QSWLTA--TSTSRVQVILLPQPPRCQSRIARTLPADQKPECRPYWEKDD 474

+ LTA S + Q + RCQSRIARTLPADQKPECRPYWEKDD


Range 1: 37 to 541








M Q + + A+ T+R Q + RCQSRIARTLPADQKPECRPYWEKD
Sbjct 457 VKREGLPMEQRNEILTAILASLTAR-QNLRREWHARCQSRIARTLPADQKPECRPYWEKD 515

D SMPLPFDLTD+VSELRGQLLEAKP
Sbjct 516 DVSMPLPFDLTDLVSELRGQLLEAKP 541

Range 1: 37 to 541









Sbjct 516 DISMPLPFDLTDIVSELRGQLLEAKP 541

Range 1: 1 to 515






Query 411 EGV------------MEFHSRCPGWSAMAQSWLTATSTSRVQVILLPQPPRCQSRIARTL 458

EGV + R +A+ S LTA R + RCQSRIARTL
Sbjct 421 EGVTNAVLHEVKREGLPVEQRNEILTAILAS-LTARHNLRRE-----WHARCQSRIARTL 474

PADQKPECRPYWEKDDASMPLPFDLTDIVSELRG LLEAKP
Sbjct 475 PADQKPECRPYWEKDDASMPLPFDLTDIVSELRGHLLEAKP 515

fascicularis]
atys]
Range 1: 37 to 541









Range 1: 1 to 505










tephrosceles]
Range 1: 37 to 541










francoisi]
Range 1: 37 to 541










Range 1: 1 to 515







E V H + Q + + A+ T+R Q + RCQSRIARTLPADQK
Sbjct 421 EAVTNAVLHEVKREGLPVEQRNEILTAILASLTAR-QNLRREWHARCQSRIARTLPADQK 479

PECRPYWEKDD SMPLPFDLTDIVSELRGQLLEAKP
Sbjct 480 PECRPYWEKDDVSMPLPFDLTDIVSELRGQLLEAKP 515

Range 1: 37 to 541







PAVLKQGEEI +VEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGV H
Sbjct 397 PAVLKQGEEIXXQVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVTNAVLHE 456


Range 1: 1 to 505










Range 1: 1 to 500








Query 474 DASMPLPFDLTDIVSELRGQL 494

D SMPLPFDLTDIVSELR ++
Sbjct 480 DVSMPLPFDLTDIVSELRDRV 500

Range 1: 1 to 505








Sbjct 421 VKGEGLPMEQRNEILTAILASLTAR-QNLRREWHARCQSRIARTLPADQKPECRPYWEKD 479


Range 1: 1 to 497







Query 474 DASMPLPFDLTDIVSELR 491

D SMPLPFDLTDIVSELR
Sbjct 480 DVSMPLPFDLTDIVSELR 497

Range 1: 1 to 515









PECRPYWEKDD SMPLPFDLTDIVSELRGQLLEAKP
Sbjct 480 PECRPYWEKDDVSMPLPFDLTDIVSELRGQLLEAKP 515
construct]
Range 1: 1 to 505









Range 1: 1 to 505







PAVLKQGEEIHNEVEFEWLRQFWFQGNRYR+CTDWWCQPMAQLEALWKKMEGV H
Sbjct 361 PAVLKQGEEIHNEVEFEWLRQFWFQGNRYRRCTDWWCQPMAQLEALWKKMEGVTNAVLHE 420



Range 1: 1 to 505







PAVLKQGEEIHNEVEFEWLRQFWFQG+RY+KCTDWWCQPMAQLE LWKKMEGV H
Sbjct 361 PAVLKQGEEIHNEVEFEWLRQFWFQGSRYKKCTDWWCQPMAQLEELWKKMEGVTNAVLHE 420


DASMPLPFDLTDIVSELRGQLLEA+P
Sbjct 480 DASMPLPFDLTDIVSELRGQLLEARP 505

Range 1: 37 to 535







Query 474 DASMPLPFDLTDIVSELRGQ 493

D SMPLPFDLTDIVSELR +
Sbjct 516 DVSMPLPFDLTDIVSELRAE 535

Range 1: 24 to 528







PAVLKQGEEIHNEVEFEWLRQFWFQGNRY+KCTDWWCQPMAQLE LWKKMEGV H



Range 1: 1 to 505










Range 1: 37 to 534








Query 474 DASMPLPFDLTDIVSELRG 492

D SMPLPFDLTDIVSELRG
Sbjct 516 DVSMPLPFDLTDIVSELRG 534

fascicularis]
Range 1: 37 to 533








D SMPLPFDLTDIVSELR
Sbjct 516 DVSMPLPFDLTDIVSELR 533

Range 1: 1 to 515







EGV H M Q + + A+ T+R Q + RCQSRIARTLPADQK
Sbjct 421 EGVTNAVLHEVKGEGLPMEQRNEILTAILASLTAR-QNLRREWHARCQSRIARTLPADQK 479


Range 1: 1 to 515








EGV H M Q + + A+ T+R Q + RCQSRIARTLPADQK
Sbjct 421 EGVTNAVLHEVKREGLPMEQRNEILTAILASLTAR-QNLRREWHARCQSRIARTLPADQK 479


Range 1: 24 to 528










boliviensis]
Range 1: 15 to 519






PAVLKQGEEIHNEVEFEWLRQFWFQGNRY+KCTDWWCQPMAQLE +WKKMEGV H
Sbjct 375 PAVLKQGEEIHNEVEFEWLRQFWFQGNRYKKCTDWWCQPMAQLEEMWKKMEGVTNAVLHE 434


DASM LPFDLTDIVSELRGQLLE +P
Sbjct 494 DASMHLPFDLTDIVSELRGQLLEGRP 519

Range 1: 1 to 515










Range 1: 24 to 528








DASMPLPFDLTD+VSELRGQLLEA+P
Sbjct 503 DASMPLPFDLTDVVSELRGQLLEARP 528

Range 1: 1 to 505







PAVLKQGEEIHNEVEFEWLR FWFQGNRYRKCTDWWCQP+A LEALWKKMEGV H
Sbjct 361 PAVLKQGEEIHNEVEFEWLRXFWFQGNRYRKCTDWWCQPVAHLEALWKKMEGVTNAVLHE 420

+ Q + + A+ T+R Q + RCQS+IARTLPADQKPECRPYWEKD
Sbjct 421 VKREGLPVEQRNEILTAILASLTAR-QNLRREWHARCQSQIARTLPADQKPECRPYWEKD 479
D SMPLPFDLTDIVSELRGQLL+AKP
Sbjct 480 DISMPLPFDLTDIVSELRGQLLKAKP 505

Range 1: 1 to 500








Query 474 DASMPLPFDLTDIVSELRGQL 494

DASMPLPFDLTDIVSELR ++
Sbjct 480 DASMPLPFDLTDIVSELRDRV 500

Range 1: 1 to 497









DASMPLPFDLTDIVSELR
Sbjct 480 DASMPLPFDLTDIVSELR 497

Range 1: 24 to 528






PAVLKQGEEIHNEVEFEWLRQFWFQGNRY+KCTDWWCQPM QLE LWKKMEGV R
Sbjct 384 PAVLKQGEEIHNEVEFEWLRQFWFQGNRYKKCTDWWCQPMTQLEELWKKMEGVTNAVLRE 443

+ LTA S + Q + RCQ RIARTLP DQKPECRPYWEK+D

Sbjct 504 PSMPLPFDLTDVVSELRGQLLEAKP 528

sabaeus]
Range 1: 6 to 496






Query 375 EFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVMEFHSRCPGWSAMA----QSW 430
EFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGV R +
Sbjct 366 EFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVTNAVLREVKREGLPVEQRNEI 425
Query 431 LTA--TSTSRVQVILLPQPPRCQSRIARTLPADQKPECRPYWEKDDASMPLPFDLTDIVS 488

LTA S + Q + RCQSRIARTLPADQKPECRPYWEKDD SMPLPFDLTDIVS

ELRGQLLEAKP

Range 1: 1 to 505







PAVLKQGEEIHNEVEFEWLRQFWFQGN YRKCTDWWCQP+AQLEALWKKMEGV H
Sbjct 361 PAVLKQGEEIHNEVEFEWLRQFWFQGNGYRKCTDWWCQPVAQLEALWKKMEGVTNAVLHE 420

+ Q + + A+ T+R Q + RCQS+IARTLPADQKPECRPYWEKD
Sbjct 421 VKREGLPVEQRNEILTAILASLTAR-QNLRREWHARCQSQIARTLPADQKPECRPYWEKD 479

D SMPLPFDLTDIVSELRGQLL+AKP
Sbjct 480 DISMPLPFDLTDIVSELRGQLLKAKP 505
Range 1: 24 to 559







Query 390 RKCTDWWCQPMAQLEALWKKMEGVME--FHSRCPGWSAMAQ-----SWLTATSTSRVQVI 442

+KCTDWWCQPMAQLE LWKKMEGV H + Q + + A+ T+R Q +
Sbjct 444 KKCTDWWCQPMAQLEELWKKMEGVTNAVLHEVKREGLPVEQRNEILTAILASLTAR-QNL 502
Query 443 LLPQPPRCQSRIARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRGQLLEAKP 499

RCQSRIARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRGQLLEA+P
Sbjct 503 RREWHARCQSRIARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRGQLLEARP 559

atys]
Range 1: 10 to 499






Query 376 FEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVME--FHSRCPGWSAMAQ----- 428

FEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGV H + Q
Query 429 SWLTATSTSRVQVILLPQPPRCQSRIARTLPADQKPECRPYWEKDDASMPLPFDLTDIVS 488

+ + A+ T+R Q + RCQSRIARTLPADQKPECRPYWEKDD SMPLPFDLTDIVS
Sbjct 430 TAILASLTAR-QNLRREWHARCQSRIARTLPADQKPECRPYWEKDDVSMPLPFDLTDIVS 488

ELRGQLLEAKP

atys]
Range 1: 3 to 492








ELRGQLLEAKP

Range 1: 16 to 506






Query 375 EFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVME--FHSRCPGWSAMAQ---- 428

EFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGV H M Q
Sbjct 376 EFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVTNAVLHEVKREGLPMEQRNEI 435
Query 429 -SWLTATSTSRVQVILLPQPPRCQSRIARTLPADQKPECRPYWEKDDASMPLPFDLTDIV 487

+ + A+ T+R Q + RCQSRIARTLPADQKPECRPYWEKDD SMPLPFDLTD+V
Sbjct 436 LTAILASLTAR-QNLRREWHARCQSRIARTLPADQKPECRPYWEKDDVSMPLPFDLTDLV 494
Query 488 SELRGQLLEAKP 499

SELRGQLLEAKP
Sbjct 495 SELRGQLLEAKP 506

Range 1: 13 to 512






Query 366 QGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVME--FHSRCPGW 423

QGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKME V H
Query 424 SAMAQ-----SWLTATSTSRVQVILLPQPPRCQSRIARTLPADQKPECRPYWEKDDASMP 478

+ Q + + A+ T+R Q + RCQSRIARTLPADQKPECRPYWEKDD SMP
Sbjct 433 LPVEQRNEILTAILASLTAR-QNLRREWHARCQSRIARTLPADQKPECRPYWEKDDVSMP 491

coquereli]
Range 1: 1 to 505







PAVLKQGEEIHNEVEFEWLRQFWFQGNRY+KCTDWWCQPM QLE WKKMEGV R


SMPLPFDLTDIVS+LRGQLLEAKP
Sbjct 481 PSMPLPFDLTDIVSDLRGQLLEAKP 505

palliatus]
Range 1: 37 to 541









Range 1: 2 to 485







Query 489 ELRGQ 493

ELR +
Sbjct 481 ELRAE 485

fascicularis]
Range 1: 3 to 484







Query 489 ELR 491

ELR
Sbjct 482 ELR 484

Range 1: 16 to 499






Query 375 EFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVME--FHSRCPGWSAMAQ---- 428

EFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGV H + Q
Sbjct 376 EFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVTNAVLHEVKREGLPVEQRNEI 435
Query 429 -SWLTATSTSRVQVILLPQPPRCQSRIARTLPADQKPECRPYWEKDDASMPLPFDLTDIV 487

+ + A+ T+R Q + RCQSRIARTLPADQKPECRPYWEKDD SMPLPFDLTDIV
Sbjct 436 LTAILASLTAR-QNLRREWHARCQSRIARTLPADQKPECRPYWEKDDVSMPLPFDLTDIV 494
Query 488 SELRG 492

SELRG
Sbjct 495 SELRG 499

coquereli]
Range 1: 1 to 498







PAVLKQGEEIHNEVEFEWLRQFWFQGNRY+KCTDWWCQPM QLE WKKMEGV R


SMPLPFDLTDIVS+LRG
Sbjct 481 PSMPLPFDLTDIVSDLRG 498

Range 1: 13 to 512





Query 366 QGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVME--FHSRCPGW 423

QGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGV H
Query 424 SAMAQ-----SWLTATSTSRVQVILLPQPPRCQSRIARTLPADQKPECRPYWEKDDASMP 478

M Q + + A+ T+R Q + RCQSRIARTLPADQKPECRPYWEKDDASMP
Sbjct 433 LPMEQRNEILTAILASLTAR-QNLRREWHARCQSRIARTLPADQKPECRPYWEKDDASMP 491


Range 1: 1 to 504






PAVLKQGEEIHNEVEFEWLRQFWFQGNRY+KCTDWWCQPM QLE LWK+MEGV H
Sbjct 360 PAVLKQGEEIHNEVEFEWLRQFWFQGNRYKKCTDWWCQPMTQLEELWKRMEGVTNAVLHE 419
Query 419 RCPGWSAMAQSWLTATSTSRVQVILLPQ-----------PPRCQSRIARTLPADQKPECR 467

+ + L + + +LP RCQ RIARTLP DQKPECR
Sbjct 420 -------VKREGLPVEQRNEILTAVLPLLTTRQNLRREWHARCQCRIARTLPVDQKPECR 472

PYWEKDD SMPLPFDLTDIVSELR QLLEAKP
Sbjct 473 PYWEKDDPSMPLPFDLTDIVSELRSQLLEAKP 504

Range 1: 1 to 504







PA+LKQGEEIHNEVEFEWLRQFWFQG+RYRKCTDWWC+PM++LE LWKKME V R
Query 421 PGWSAMAQSWLTATSTSRVQVILLPQP------PRCQSRIARTLPADQKPECRPYWEKDD 474

+ T+ + + Q RCQ RIARTLP DQKP+CRPYWEKDD


Range 1: 1 to 504










Range 1: 1 to 504










Range 1: 1 to 504










Range 1: 1 to 506




Query 241 AVAVYSY-SCEGPEEESEDDSHLEGRDPDIWHVGFKISWDIETPGLAIPLHQGDCYFMLD 299

AVAVY+Y E EEESEDDSHLEGRDPDIWHVGFKISWDIETPGLAIPLHQGDCYFMLD

Query 360 EPAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVME--FH 417

EPAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPM LE LWKKMEGV H
Sbjct 361 EPAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMTHLEGLWKKMEGVTNAVLH 420
Query 418 SRCPGWSAMAQ-----SWLTATSTSRVQVILLPQPPRCQSRIARTLPADQKPECRPYWEK 472

+ Q + + A T+R Q + RCQSRIARTLP DQKPECRPYWEK
Sbjct 421 EVKREGLPVEQRNEILTAILALLTTR-QNLRREWHARCQSRIARTLPGDQKPECRPYWEK 479
Query 473 DDASMPLPFDLTDIVSELRGQLLEAKP 499

DD SMPLPFDLTDIVSELRG LLEAKP
Sbjct 480 DDPSMPLPFDLTDIVSELRGLLLEAKP 506

Range 1: 1 to 505






Query 361 PAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVMEF---H 417

PAVLKQGEEIHNEVEFEWLRQFWFQGNRY+KCTDWW QPM QLE LWKKMEGV
Sbjct 361 PAVLKQGEEIHNEVEFEWLRQFWFQGNRYKKCTDWWWQPMTQLEELWKKMEGVTNAVLQE 420
Query 418 SRCPGWSAMAQ----SWLTATSTSRVQVILLPQPPRCQSRIARTLPADQKPECRPYWEKD 473

R G + + + A T+R Q + RCQ RIAR+LPADQKPECRPYWEKD
Sbjct 421 VRREGAPVEQRNKILTAILAVLTTR-QNLRREWHARCQCRIARSLPADQKPECRPYWEKD 479

D SMPLPFDLTDIVSELRG LLEAKP
Sbjct 480 DPSMPLPFDLTDIVSELRGLLLEAKP 505

Range 1: 15 to 519








R G + + + AT T+R Q + RCQSRIARTLPADQKPECRPYWEKD
Sbjct 435 VRREGTPVEQRNEILTAILATLTAR-QNLRREWHARCQSRIARTLPADQKPECRPYWEKD 493

D SMPLPFDLTDI+SELR LLEAKP
Sbjct 494 DPSMPLPFDLTDIISELRSLLLEAKP 519

Range 1: 1 to 505







PAVLKQGEEIHNEVEFEWLRQFWFQGNRY+KCT+WWCQPM QLE LWKKMEGV H
Sbjct 361 PAVLKQGEEIHNEVEFEWLRQFWFQGNRYKKCTNWWCQPMTQLEELWKKMEGVTNAVLHE 420

+ + Q + + A T+R Q + RCQ RIAR+LPADQKPECRPYWEKD
Sbjct 421 VRREGAPVEQRNKILTAILAVLTTR-QNLRREWHARCQCRIARSLPADQKPECRPYWEKD 479

D SMPLPF+LTDIVSELRG LLEAKP
Sbjct 480 DPSMPLPFELTDIVSELRGLLLEAKP 505

Range 1: 1 to 505





Query 361 PAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVME---FH 417

Sbjct 361 PAVLKQGEEIHNEVEFEWLRQFWFQGNRYKKCTDWWCQPMTQLEELWKKMEGVTNAVLHE 420

R G + + + A+ T+R Q + RCQ RIARTLP DQKPECRPYWEKD
Sbjct 421 VRREGVPVEQRNEILTAILASLTTR-QNLRREWHARCQCRIARTLPVDQKPECRPYWEKD 479

D SMPLPFDLTDI+SELRG LLEAKP
Sbjct 480 DPSMPLPFDLTDIISELRGLLLEAKP 505

Range 1: 15 to 519







R G + + + AT T+R Q + RCQSRIARTLPADQKPECRPYWEKD
Sbjct 435 VRREGTPVEQRNEILTAILATLTAR-QNLRREWHARCQSRIARTLPADQKPECRPYWEKD 493

D SMPLPFDLTDI+SELR LLEAKP
Sbjct 494 DPSMPLPFDLTDIISELRSLLLEAKP 519

Range 1: 1 to 504








R G + + + A+ T+R Q + RCQSRIARTLP DQKPECRPYWEKD
Sbjct 420 VRREGVPVEQRNEILTAILASLTTR-QNLRREWHARCQSRIARTLPVDQKPECRPYWEKD 478

D SMPLPFDLTD+VSELRG LLEAKP
Sbjct 479 DPSMPLPFDLTDVVSELRGLLLEAKP 504

Range 1: 1 to 505







PAVLKQGEEIHNEVEFEWLRQFWFQGNRY+KCTDWWCQPM QLE LWKKME V H

+ Q + + A+ T+R Q + RCQ RIARTLP DQKPECRPYWEKD
Sbjct 421 VRQEGVPVEQRNEILTAILASLTTR-QNLRREWHARCQCRIARTLPVDQKPECRPYWEKD 479


Range 1: 1 to 505






PAVLKQGEEIHNEVEFEWLRQFWFQGNRY+KCTDWWCQPM QLE LWKKME V H

+ Q + + A+ T+R Q + RCQ RIARTLP DQKPECRPYWEKD
Sbjct 421 VRREGVPVEQRNEILTAILASLTTR-QNLRREWHARCQCRIARTLPVDQKPECRPYWEKD 479


Range 1: 1 to 504






PAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKC+DWWCQPMAQLE LWKKMEGV H
Sbjct 360 PAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCSDWWCQPMAQLEELWKKMEGVTNAVLHE 419

+ Q + + A TSR Q + RCQSRIARTLP DQKPECRPYWEKD
Sbjct 420 VRREGVPVEQRNEILTAILALLTSR-QNLRREWHARCQSRIARTLPVDQKPECRPYWEKD 478


Range 1: 1 to 504










Range 1: 1 to 479










Range 1: 1 to 504







P VLKQGEEIHNEVEFEWLRQFWFQGNRYRKC+DWWCQPMAQLE LWKKMEGV
Sbjct 360 PVVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCSDWWCQPMAQLEELWKKMEGVTNAVLRE 419

R G + + + A TSR Q + RCQSRIARTLP DQKPECRPYWEKD
Sbjct 420 VRREGVPVEQRNEILTAILALLTSR-QNLRREWHARCQSRIARTLPVDQKPECRPYWEKD 478

>FTo [Sus scrofa]

>FTO [Sus scrofa]
scrofa]
Range 1: 1 to 505






PAVLKQGEEIHNEVEFEWLRQFWFQGNRY+KCTDWWCQPM QLE LWKKMEG R

+ T+ + V+ Q RCQSRIARTLP DQKPECRPYWEKDD


Range 1: 1 to 505









Range 1: 3 to 478







RKCTDWWCQPMAQLEALWKKMEGV H + Q + + A+ T+R Q +
Sbjct 363 RKCTDWWCQPMAQLEALWKKMEGVTNAVLHEVKREGLPVEQRNEILTAILASLTAR-QNL 421

RCQSRIARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRGQLLEAKP
Sbjct 422 RREWHARCQSRIARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRGQLLEAKP 478
FTO [Homo sapiens]
FTO [Homo sapiens]
FTO [Homo sapiens]
FTO [Homo sapiens]
FTO [Homo sapiens]
FTO [Homo sapiens]
FTO [Homo sapiens]
FTO [Homo sapiens]
Fto [Homo sapiens]
Range 1: 20 to 495







>fat mass and obesity-associated protein [Sus scrofa]

Sequence ID: ACY82516.1 Length: 505
Range 1: 1 to 505






LNATHQHCVLAG PRFSST RVAECSTGTLDYILQRCQLALQNV D+ D+ +VSLKS E
Sbjct 301 LNATHQHCVLAGLPPRFSSTRRVAECSTGTLDYILQRCQLALQNVRDEADSGEVSLKSLE 360




Range 1: 1 to 413






Query 361 PAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGV 413

Sbjct 361 PAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGV 413

Range 1: 1 to 413







Range 1: 1 to 413








Range 1: 1 to 413







Range 1: 1 to 413







Range 1: 1 to 413








Range 1: 1 to 504






P+VLKQGEEIHNEVEFEWLRQFWFQGNRYRKC+DWWCQPMAQLE LWKKMEGV
Sbjct 360 PSVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCSDWWCQPMAQLEELWKKMEGVTNAVLRE 419


D SMPLPFDLTD VSELRG LLEAKP
Sbjct 479 DPSMPLPFDLTDAVSELRGLLLEAKP 504

Range 1: 1 to 413







Range 1: 1 to 421







PAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGV+ + C
Sbjct 361 PAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVVPV-TNC 419
Query 421 PG 422

P
Sbjct 420 PN 421

Sequence ID: AFX62367.1 Length: 505
Range 1: 1 to 505




MGSS++G DEVD KSRAAYN+TLLNFMDPQKMP LKEEPYFGMGKMAVSWHHDENLVDRS
Sbjct 181 MGSSFDGHDEVDRKSRAAYNLTLLNFMDPQKMPCLKEEPYFGMGKMAVSWHHDENLVDRS 240

AVAVY+YSCEGPEEESEDD LEGRDPD+WHVGFKISWDIETPGLAIPLH+GDCYFMLDD
Sbjct 241 AVAVYNYSCEGPEEESEDDPQLEGRDPDVWHVGFKISWDIETPGLAIPLHRGDCYFMLDD 300



Sbjct 421 VRREGAPVEQSSDILTAILAVLTARQNLRREWHARCQSRIARTLPVDQKPECRPYWEKDD 480


Range 1: 1 to 413







Range 1: 1 to 413







Range 1: 3 to 476







Query 443 LLPQPPRCQSRIARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRGQLLEA 497

RCQSRIARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRGQLLEA
Sbjct 422 RREWHARCQSRIARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRGQLLEA 476

Range 1: 1 to 504






PAVLKQGEEIHNEVEFEWLRQ+WFQGNRYRKCTDWWCQPM QLE LWKKMEGV R
Sbjct 360 PAVLKQGEEIHNEVEFEWLRQYWFQGNRYRKCTDWWCQPMTQLEGLWKKMEGVTNAVLRE 419

+ T T+ + ++ Q RCQSRIARTLP DQKPECRPYWEKDD


Range 1: 4 to 479









Range 1: 4 to 476







Query 443 LLPQPPRCQSRIARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRGQLLE 496

RCQSRIARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRGQLLE
Sbjct 423 RREWHARCQSRIARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRGQLLE 476

Range 1: 46 to 549








>alpha-ketoglutarate-dependent dioxygenase FTO isoform X2 [Bubalus bubalis]

Range 1: 1 to 505

MKRTPTAEEREREAKKLRLLEELEDTWLPYLTPKDDEFYQQWQLKYPKLILREA+SV E
Sbjct 1 MKRTPTAEEREREAKKLRLLEELEDTWLPYLTPKDDEFYQQWQLKYPKLILREAASVPEL 60

LHKEVQ+AFLTLHKHGCLFRDLVRIQGKDLLTPVSRILIGNPGCTYKYLNTRLFTVPWPV
Sbjct 61 LHKEVQQAFLTLHKHGCLFRDLVRIQGKDLLTPVSRILIGNPGCTYKYLNTRLFTVPWPV 120

KGS+ K+ EAEIAAAC+TFLKLN YLQ+ETIQALEELAAKEKAN DAVP+C+ DFPRVG
Sbjct 121 KGSDAKYNEAEIAAACQTFLKLNSYLQVETIQALEELAAKEKANIDAVPVCIGPDFPRVG 180

MGSS++G DE+D+K+RAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLVDRS
Sbjct 181 MGSSFDGHDEIDMKNRAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLVDRS 240


LNATHQHCVLAG PRFSSTHRVAECSTGTL+YILQRCQ+ALQNV D+ DN ++SLKS E
Sbjct 301 LNATHQHCVLAGLPPRFSSTHRVAECSTGTLEYILQRCQVALQNVRDEADNGEISLKSLE 360

VLKQGEEIHNEVEFEWLRQFWFQG+RY+KCTDWWCQPM+QLE +W+KME + R
Sbjct 361 SVVLKQGEEIHNEVEFEWLRQFWFQGSRYKKCTDWWCQPMSQLEEMWRKMEWLTSAVLRE 420

+ TS + I Q RCQSRIARTLPADQKPECRPYWEK D
Sbjct 421 VRREGVPMEQKNEMLTSILASITTRQNLRREWHARCQSRIARTLPADQKPECRPYWEKGD 480

SMPLPFDLT+IVSELRG LLE +P
Sbjct 481 PSMPLPFDLTEIVSELRGLLLETRP 505

Range 1: 20 to 492







Query 443 LLPQPPRCQSRIARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRGQLLE 496

RCQSRIARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRGQLLE
Sbjct 439 RREWHARCQSRIARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRGQLLE 492

Range 1: 46 to 549










Range 1: 1 to 479










Range 1: 1 to 504










Blast Proteine Cu NR Acces

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Blast Proteine Cu NR Acces

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RID: U81HR50K01R

Sequences producing significant alignments:

Score:1053 bits(2724), Expect:0.0,

Query 61 LHKEVQEAFLTLHKHGCLFRDLVRIQGKDLLTPVSRILIGNPGCTYKYLNTRLFTVPWPV 120

Query 121 KGSNIKHTEAEIAAACETFLKLNDYLQIETIQALEELAAKEKANEDAVPLCMSADFPRVG 180

Query 181 MGSSYNGQDEVDIKSRAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLVDRS 240

Query 241 AVAVYSYSCEGPEEESEDDSHLEGRDPDIWHVGFKISWDIETPGLAIPLHQGDCYFMLDD 300

Query 301 LNATHQHCVLAGSQPRFSSTHRVAECSTGTLDYILQRCQLALQNVCDDVDNDDVSLKSFE 360

Query 361 PAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVTNAVLHE 420

Query 421 VKREGLPVEQRNEILTAILASLTARQNLRREWHARCQSRIARTLPADQKPECRPYWEKDD 480

Query 481 ASMPLPFDLTDIVSELRGQLLEAKP 505

>alpha-ketoglutarate-dependent dioxygenase FTO isoform X3 [Pan paniscus]

Score:1052 bits(2721), Expect:0.0,

Query 61 LHKEVQEAFLTLHKHGCLFRDLVRIQGKDLLTPVSRILIGNPGCTYKYLNTRLFTVPWPV 120

Query 121 KGSNIKHTEAEIAAACETFLKLNDYLQIETIQALEELAAKEKANEDAVPLCMSADFPRVG 180

Query 241 AVAVYSYSCEGPEEESEDDSHLEGRDPDIWHVGFKISWDIETPGLAIPLHQGDCYFMLDD 300

Query 301 LNATHQHCVLAGSQPRFSSTHRVAECSTGTLDYILQRCQLALQNVCDDVDNDDVSLKSFE 360

Query 361 PAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVTNAVLHE 420

Query 421 VKREGLPVEQRNEILTAILASLTARQNLRREWHARCQSRIARTLPADQKPECRPYWEKDD 480

Query 481 ASMPLPFDLTDIVSELRGQLLEAKP 505

>unnamed protein product [Homo sapiens]

Score:1052 bits(2721), Expect:0.0,

Query 61 LHKEVQEAFLTLHKHGCLFRDLVRIQGKDLLTPVSRILIGNPGCTYKYLNTRLFTVPWPV 120

Query 121 KGSNIKHTEAEIAAACETFLKLNDYLQIETIQALEELAAKEKANEDAVPLCMSADFPRVG 180

Query 181 MGSSYNGQDEVDIKSRAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLVDRS 240

Query 241 AVAVYSYSCEGPEEESEDDSHLEGRDPDIWHVGFKISWDIETPGLAIPLHQGDCYFMLDD 300

Query 301 LNATHQHCVLAGSQPRFSSTHRVAECSTGTLDYILQRCQLALQNVCDDVDNDDVSLKSFE 360

Query 421 VKREGLPVEQRNEILTAILASLTARQNLRREWHARCQSRIARTLPADQKPECRPYWEKDD 480

Query 481 ASMPLPFDLTDIVSELRGQLLEAKP 505

>alpha-ketoglutarate-dependent dioxygenase FTO isoform X2 [Hylobates moloch]

Score:1050 bits(2716), Expect:0.0,

Query 61 LHKEVQEAFLTLHKHGCLFRDLVRIQGKDLLTPVSRILIGNPGCTYKYLNTRLFTVPWPV 120

Query 121 KGSNIKHTEAEIAAACETFLKLNDYLQIETIQALEELAAKEKANEDAVPLCMSADFPRVG 180

Query 181 MGSSYNGQDEVDIKSRAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLVDRS 240

Query 241 AVAVYSYSCEGPEEESEDDSHLEGRDPDIWHVGFKISWDIETPGLAIPLHQGDCYFMLDD 300

Query 301 LNATHQHCVLAGSQPRFSSTHRVAECSTGTLDYILQRCQLALQNVCDDVDNDDVSLKSFE 360

Query 361 PAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVTNAVLHE 420

Query 421 VKREGLPVEQRNEILTAILASLTARQNLRREWHARCQSRIARTLPADQKPECRPYWEKDD 480

Query 481 ASMPLPFDLTDIVSELRGQLLEAKP 505

Score:1050 bits(2714), Expect:0.0,

Query 61 LHKEVQEAFLTLHKHGCLFRDLVRIQGKDLLTPVSRILIGNPGCTYKYLNTRLFTVPWPV 120

Query 121 KGSNIKHTEAEIAAACETFLKLNDYLQIETIQALEELAAKEKANEDAVPLCMSADFPRVG 180

Query 181 MGSSYNGQDEVDIKSRAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLVDRS 240

Query 241 AVAVYSYSCEGPEEESEDDSHLEGRDPDIWHVGFKISWDIETPGLAIPLHQGDCYFMLDD 300

Query 301 LNATHQHCVLAGSQPRFSSTHRVAECSTGTLDYILQRCQLALQNVCDDVDNDDVSLKSFE 360

Query 361 PAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVTNAVLHE 420

Query 421 VKREGLPVEQRNEILTAILASLTARQNLRREWHARCQSRIARTLPADQKPECRPYWEKDD 480

Query 481 ASMPLPFDLTDIVSELRGQLLEAKP 505

>alpha-ketoglutarate-dependent dioxygenase FTO isoform X5 [Pan troglodytes]

Score:1049 bits(2713), Expect:0.0,

Query 61 LHKEVQEAFLTLHKHGCLFRDLVRIQGKDLLTPVSRILIGNPGCTYKYLNTRLFTVPWPV 120

Query 121 KGSNIKHTEAEIAAACETFLKLNDYLQIETIQALEELAAKEKANEDAVPLCMSADFPRVG 180

Query 181 MGSSYNGQDEVDIKSRAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLVDRS 240

Query 241 AVAVYSYSCEGPEEESEDDSHLEGRDPDIWHVGFKISWDIETPGLAIPLHQGDCYFMLDD 300

Query 301 LNATHQHCVLAGSQPRFSSTHRVAECSTGTLDYILQRCQLALQNVCDDVDNDDVSLKSFE 360

Query 361 PAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVTNAVLHE 420

Query 421 VKREGLPVEQRNEILTAILASLTARQNLRREWHARCQSRIARTLPADQKPECRPYWEKDD 480

Query 481 ASMPLPFDLTDIVSELRGQLLEAKP 505

>alpha-ketoglutarate-dependent dioxygenase FTO isoform 2 [Homo sapiens]

Score:1045 bits(2702), Expect:0.0,

Query 61 LHKEVQEAFLTLHKHGCLFRDLVRIQGKDLLTPVSRILIGNPGCTYKYLNTRLFTVPWPV 120

Query 121 KGSNIKHTEAEIAAACETFLKLNDYLQIETIQALEELAAKEKANEDAVPLCMSADFPRVG 180

Query 181 MGSSYNGQDEVDIKSRAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLVDRS 240