Inflammation

cell exposed to irratant

1
Reversible Cell living
L
Sympots appear
due to
accumulate
1
degenerative
disease

Seifrearfant 0 necrosis da
L
d ns cell respond
CEes by inflammation irratants
1 that
inflammatory
disease cause
necrosis

To prevent
spread

remove necrotic tissue

so defect
organ has no

severe symptoms

vigrous response
Malignant thot expressing
itself
if

necrosis for Ccw Fells mild

Response
lose few cells daily over
long time organ failure
no severe symptoms
 severe irratant

aim to A blood
suppy

fallow
leukocyte to
to
migrate
site of
igratant
destroy
Army it
of
Body
d
leukocytes
WBC 0
neutrophil
Macrophages
proteins
inplasma
macroenger
Immunoglobin

drain deoxygent
Swollen
oredimits

y mmqgqgy.gg
blood move slowly
rood
supply
to give time for
out'd
affix in leuokuyte to go
Endothelial cells
move away to give
Gap for leuokye to
pass through
 I 9

plasma
protein
comes out with plasma

1
like
thread chemical Substance
attract leukocyte
to site of
irratant

air or aww no
rag.AE EE
p j d I
 Neutrophilcoming in contact
fpaumintation with endothelium
couldtakeneutrophil away soadhesion
bloodflowing
endothelium
betw neutrophil
creatingfirm
adhesionmower

extravasation
of leukocytes
Bridge
offibrin
ward

attachesto
immungrosins
when irratane
surrounded
as
immunogiosinsmacrophage
can magamose
irratant
of leucoma a surface
Irratant shouldbeattached onimmungiosin
surface
attache to irratane speciacreceptoron
immungiobinaoessopsonization ofrecngan.EEP.oha.ge gYoasIs

d d d
im coating
macrophageirratanth
gains Empient

t.ws can comment

onysoke
irravent
recognizes immungiobin
aEach
sina.ae

irratant attached surface

Macrophage will extend its to
cytoplasm aroundirratane
T around
racon
of Macrophage
irraiann
lysosome became attached
topnagbomsome

to phagosome
discharge lysosomal enzymes
1
d To kill
e irratant
Oh
dependent cytoplasm has NADPH oxidase
myelopaeroxidase
in
Cytoplasmic Dart attaches
to membranous part of phagosom
fa n so enzyme can work
generate'Iree T.diadraa.ae
fromoxygen

contact with edothelium g

O
lysosome

or

attachments crepe'Ifosone
how
it µn engulfment
destrot
will.pro destruction
thesomeenzyme
or
free radial
 Inflammatory
0 edema of
Inflamnal

beer
of
ascoidpore
eider
seethe
doffate
responds
for
fibrin protein clotting

d 3plasma
neutrophil protein
Macrophages
dqqfi.frdi t
globulin
gotEn'Tfibroges
albumin
ostmotic
pressure
pofasma

crease
vasular
permiabilz
vasodiano

gross
examination
of
emotaxis acute
inflammation

causes
sinus opain
nereneaing

XUEcomplain

1role
of
Tin
Biopsying

fun of blood

inflammatory Exudate

Sneutroph
esinophol
macrophaget
 0 redness hyperemia
pus pus a lot of neutrophil hotness
exudate d
detad
living swelling 0 edema
or
exudate
filled 0
with pain
pus limited
supprative 0 function
1
No pus

in 094
took
juicy

to enE a taxi n
aim
inflammation thffenane opening

i
back
of
Neck

Abcesspathology 0
opening
O
necrosis
center of liquefactive
pus
dead
neutrophil inflammatory
exdute
surrounded by signsof
inflammation0 Dilated
conjusted
vessel
Edema
neutrophil
living
hair follicle trunk
if close to Carbunc
back of n.eck multiple opening d
clinifganifers early sign of diabetes
doaefpendectomy

airdischarge
a
IN8u
 fidgap
w
by
toughonager
1 c
Replace
deadcells
1
byforming
healthy
new similar
cells

becomes
Chronic
chronic
on
w
weakened topof
reduced acute