DRUG STUDY

Name of Drug: Amoxiclav

Drug Dosage/Route Classification Mechanisms of Action Indication Contraindication Adverse Effects Nursing Considerations

Generic Name: 5 ml BID for 7 Antibiotic Clavulanic acid contains a beta-  Bacterial Infections - diarrhea from an - Nausea Assessment & Drug Effects
Amoxiclav days PO lactam ring in its structure that  Bloodstream Infections infection with Clostridium - Vomiting
binds in an irreversible fashion  Bone and Joint Infections difficile bacteria. - Headache - Determine previous hypersensitivity
Brand Name: to beta-lactamases, preventing  Gynaecological infection - Diarrhea reactions to penicillins, cephalosporins,
AmoClav them from inactivating certain  Intraabdominal Infections - mononucleosis. - Gas and other allergens prior to therapy.
beta-lactam antibiotics, with  Lower Respiratory Tract - Stomach pain - Lab tests: Baseline C&S tests prior to
efficacy in treating susceptible Infection (LRTI) - the kissing disease. - Skin rash or itching initiation of therapy; start drug pending
gram-positive and gram- - White patches in results.
 Otitis Media (OM)
negative infections. - liver problems. your mouth or - Monitor for S&S of an urticarial rash
 Sinusitis
throat (usually occurring within a few days after
 Skin and Subcutaneous Tissue - blockage of normal bile - Vaginal yeast start of drug) suggestive of a
Bacterial Infections flow. infection (itching or hypersensitivity reaction. If it occurs, look
 Urinary Tract Infection discharge) for other signs of hypersensitivity (fever,
 Skin and skin-structure infections - severe renal impairment. wheezing, generalized itching, dyspnea),
and report to physician immediately.
- Note: Generalized, erythematous,
maculopapular rash (ampicillin rash) is not
due to hypersensitivity. It is usually mild,
but can be severe. Report onset of rash to
physician, since hypersensitivity should be
ruled out.

Patient & Family Education

- Female patients should report onset of

symptoms of Candidal vaginitis (e.g.,
moderate amount of white, cheesy,
nonodorous vaginal discharge; vaginal
inflammation and itching; vulvar
excoriation, inflammation, burning, itching).
Therapy may have to be discontinued.
- Note: Use Clinistix or TesTape when
monitoring urinary glucose to avoid false
readings with diabetes mellitus.
- Do not breast feed while taking this drug
without consulting physician.