Far Eastern University

Institute of Nursing

Louielyn V.Paragas

BSN 301

Drug Study

Generic/ Drug Class: Dosage Indication: Contraindication: Adverse/Side Nursing

Brand Name: Effects: Responsibilities:
Olanzapine Antipsychotic 5-10  Treatment of  Contraindicated Adverse effects:  Inspect I.M.
-Zyprexa Dopaminergic mg schizophrenia with allergy to somnolence, solution for
blocker BID  Acute mixed olanzapine, dizziness, particulate matter
or manic myeloproliferati nervousness, and discoloration
episodes ve disorders, headache, before
associated severe CNS akathisia, administration.
with bipolar 1 depression, personality  Encourage patient
disorder and comatose states, disorders, tardive to void before
maintenance and lactation. dyskinesia, taking the drug to
of bipolar 1 neuroleptic help decrease
disorder as malignant anticholinergic
monotherapy syndrome, effects of urinary
or combined orthostatic retention
with lithium hypotension,  Monitor for
or valproate peripheral elevations of
 Agitation edema, temperature and
associated tachycardia, differentiate
with constipation, between infection
schizophrenia abdominal pain, and neuroleptic
and bipolar 1 cough, malignant
mania pharyngitis, syndrome.
 (injection)  Monitor for
Side effects: orthostatic
Drowsiness, hypotension and
dizziness, provide
sedation, appropriate safety
seizures, measures as
increased needed.
salivation,  Monitor patient
constipation and regularly for signs
fast heart rate. and symptoms of
diabetes mellitus;
monitor lipid and
triglyceride
levels.
 Peel back foil on
blister pack of
disintegrating
tablets; do not
push through foil;
use dry hands to
remove tablet ,
place entire tablet
in mouth.
Divalproex Antiepileptic 250 mg  treatment of  Contraindicated Adverse effects:  Obtain liver
sodium BID acute manic in patients Sedation, tremor, function test
Depakote or mixed hypersensitive emotional upset, results, platelet
episodes to drug and in depression, count, and PT and
associated those with psychosis, INR before
with bipolar hepatic disease aggression, starting therapy,
disorder with or significant hyperactivity, and monitor these
or without hepatic behavioural values
psychotic dysfunction, deterioration, periodically.
features and in patients weakness,  Don't give syrup
 treatment of with a urea suicidality, rash, to patients who
bipolar mania cycle disorder petechiae, need sodium
 prophylaxis of (UCD). pancreatitis, restriction. Check
migraine hemorrhage, with prescriber.
headaches bone marrow  Adverse reactions
suppression, may not be
thrombocytopeni caused by
a, hepatotoxicity, valproic acid
erythema alone because it's
multiforme, usually used with
Stevens-Johnson other
syndrome, anticonvulsants.
hypersensitivity  Divalproex
reactions sodium has a
lower risk of
Side effects: adverse GI
Drowsiness, GI reactions.
upset, transient  Never withdraw
increase in hair drug suddenly
loss because sudden
withdrawal may
worsen seizures.
Call prescriber at
once if adverse
reactions develop.
 Notify prescriber
if tremors occur; a
dosage reduction
may be needed.
 Monitor drug
level. Therapeutic
level is 50 to 100
mcg/ml.
  When converting
patients from a
brand-name drug
to a generic drug,
use caution
because
breakthrough
seizures may
occur.
Diphenhydramin Antihistamine 50 mg  Relief of  Contraindicated Adverse effects:  Administer with
e hydrochloride Anti-motion PRN symptoms with allergy to Drowsiness, food if GI upset
sickness drug associated antihistamines, dizziness, occurs
Antiparkinsoni with perennial third trimester sedation,  Monitor patient
an and seasonal of pregnancy disturbed response, and
Cough allergic and lactation coordination, arrange for
suppressant rhinitis; fatigue, adjustments of
Sedative vasomotor confusion, dosage to lowest
hypnotic rhinitis; hypotension, possible effective
allergic palpitations, dose
conjunctivitis, bradycardia,  avoid alcohol,
 Active and tachycardia, serious sedation
prophylactic epigastric could occur
treatment of distress,
motion haemolytic
sickness anemia,
 night time hypoplastic
sleep aid anemia,
 Parkinsonism thrombocytopeni
a, leukopenia,
agranulocytosis,
pancytopenia,
and thickening
of bronchial
secretions.

Side effects:
Dizziness,
sedation,
drowsiness,
epigastric
distress, diarrhea
or constipation,
dry mouth, and
dryness of nasal
mucosa.