UNIVERSITAS AIRLANGGA

DIREKTORAT PENDIDIKAN
Tim Pengembangan Jurnal Universitas Airlangga
Kampus C Mulyorejo Surabaya

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 UNIVERSITAS AIRLANGGA
DIREKTORAT PENDIDIKAN
Tim Pengembangan Jurnal Universitas Airlangga
Kampus C Mulyorejo Surabaya

EDITORIAL BOARD
Dewan Redaksi

Pemimpin Redaksi : Nusdianto Triakoso, drh., M.P. Penyunting : Nusdianto Triakoso, drh. M.P. Dr. M.
Zainal Arifin, drh., M.S. Dr. I Komang Wiarsa Sardjana, drh. Prof. Dr. Bambang Sektiari, drh., DEA Ira
Sari Yudaniayanti, drh., M.P. Boedi Setiawan, drh., M.P. Julien Supraptini, drh., S.U. Handayani Tjitro,
drh., M.S. Djoko Galijono, drh., M.S. Lianny Nangoi, drh., M.Kes. Dr. E. Djoko Poetranto, drh., M.S. Dr.
Wiwik Misaco Yuniarti, drh., M.Kes Redaktur Pelaksana : Hardany Primarizky, drh., M.V.M.

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 UNIVERSITAS AIRLANGGA
DIREKTORAT PENDIDIKAN
Tim Pengembangan Jurnal Universitas Airlangga
Kampus C Mulyorejo Surabaya

Table of Contents
No Title Page

1 The Comparison of Wound Healing Time of Staphylococcus aureus Infection With 1-4
Treatment of Self Produced Apple Cider Vinegar and Commercial Apple Cider
Vinegar Topically On Mice (Mus musculus)
2 The Urolithiasis Incidence in Cats At Veterinary Teaching Hospital of Faculty 5-8
Veterinary Medicine Airlangga University in Period 2013-2014
3 The Comparison of Wound Healing Time of Staphylococcus aureus Infection 9 - 12
Between the Effect of Topical Treatment of Apple Cider Vinegar and
Oxytetracycline on Mice (Mus musculus)

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 UNIVERSITAS AIRLANGGA
DIREKTORAT PENDIDIKAN
Tim Pengembangan Jurnal Universitas Airlangga
Kampus C Mulyorejo Surabaya

Vol. 3 - No. 2 / 2015-01

TOC : 3, and page : 9 - 12

The Comparison of Wound Healing Time of Staphylococcus aureus Infection Between the Effect of
Topical Treatment of Apple Cider Vinegar and Oxytetracycline on Mice (Mus musculus)

Perbandingan Efek Pemberian Cuka Apel Dengan Oksitetrasiklin Secara Topikal Pada Mencit (Mus
muskulus) Terhadap Lama Waktu Kesembuhan Luka Infeksi Staphylococcus aureus

Author :
Yeni Purbowati | -
Fakultas Kedokteran Hewan
Erni Rosilawati SI | -
Fakultas Kedokteran Hewan
Arimbi | -
Fakultas Kedokteran Hewan

Abstract

This research was conducted to investigate the ability of apple cider vinegar, as traditional medicine
for wound healing incision on mice (Mus musculus) were infected by Staphylococcus aureus.
Eighteen of three mounth old female mice (Mus musculus) BALB/c strain with 25 gram everage body
weight was divided into three group, A, B and C. group A was given treatment with apple cider
vinegar, group B was given treatment with Oxytetracycline as antibotic and group C as a control was
not given treatmnt. Each treatment was consist of six mice (Mus musculus). The treatment was
given topically three times a day. Observation of wound healing was characterized by the exfoliation
of the scab and wound closure. The experimental design used in this study was using completely
ramdmized design (CRD). The data were analized by Analysis of Variance (ANOVA) and then was
followed by Honestly Significant Difference (HSD) test with significance of 1%. The result showed
that the treatment using apple cider vinegar and oxytetracycline affect the healing time of the
Staphylococcus aureus wound infection on mice (Mus musculus), amd the treatment indicated that
apple cider vinegar showed the best result compared to both antibiotic treatment and control.

Keyword : apple, cider, vinegar, Staphylococcus, aureus, ,

Daftar Pustaka :
1. Atma, CD, (2014). Efektifitas antibakteri cuka apel varietas Anna produk sendiri dan kemasan
terhadap pertumbuhan bakteri Staphylococcus aureus secara in vitro . Skripsi : Fakultas Kedokteran
Hewan Universitas Airlangga.
2. Katzung, BG, (2009). Basic and clinical pharmacology. 7th Edition. New York : Prentice Hall,
Appleton & Lange
3. Nayak BS, Sandiford S, Maxwell A, (2007). Evaluation of the wound-healing activity of
ethanolic extract of morinda citriflora leaf. 6(3):351-356 : Evid Based Complement Alternative
Medicine
4. Kormaz A, U Sahiner and M Yurdakok, (2000). Chemical burn caused by topical vinegar
application in a newborn infant. 17:34-36 : Pediatr Dermatol

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