Streptococcus viridans is the most common cause of endocarditis following dental or oral

procedures

rheumatoid arthritis is the autoimmune disease which improves in pregnancy

thymoma+hypogammaglobulinemia = GOOD'S syndrome

mode of adrenaline administration in anaphylactic shock is intramuscular.

steroid can precipitate scleroderma renal crisis in systemic sclerosis

activated protein c is no longer used in septic shock and is withdrawn.

IL-6 elevation is the single best predictor of multi organ failure in patient of shock

Mc organism causing severe sepsis is gram negative bacteria but mc isolated in blood is gram
positive bacteria

IPF (immature platelet fraction) is almost equivalent of reticulocyte count for platelets.being used in
dengue fever to see the need of platelet transfusion.if it's high (>10%;normal value being 1-5%)then
there is no need for prophylactic transfusion even if platelets are around 10000 as platelet count will
rise in 24-48hrs.

antibiotic in enteric fever:for empirical,multi drug resistant and flouroquonolone resistance =

ceftriaxone

the most common artery involved in takayasu vasculitis is subclavian.

Behcet's syndrome associated with-

1.HLA B 51

2.IL-10(low)

3.Anti saccharomyces cerevisiae ab

despite widespread use of ART in HIV - PML(jc virus) and AIDS associated systemic lymphomas are
the two manifestations whose incidence has NOT changed unlike KS,primary CNS lymphoma and
most of the opportunistic infections whose incidence has reduced with use of ART.

For prophylaxis of meningococcal meningitis effectiveness of rifampicin is 80-85% and ceftriaxone is

97%

Most common genotype of hepatitis B in India is D

Most common genotype of hepatitis B in North India is D

Most common serotype hepatitis B in India ayw

Significant involuntary weight loss is defined as 4.5 kg or 5% of body weight over 6-12 months period
DOC for acute adrenal crisis is iv hydrocortisone(+iv fluids). DOC for initial treatment of chronic
adrenal insufficiency is oral hydrocortisone.

PULMONARY HYPERTENSION- Screening test = ECHO ; Gold standard right heart catheterization

The definition of precapillary Pulmonary Hypertension or PAH requires (1) an increased mean
pulmonary arterial pressure (mP AP >25 mmHg); (2) a pulmonary capillary wedge pressure (PCWP) ，
left atrial pressure， or left ventricular end -diastolic pressure <15mmHg; and (3) PVR >3 Wood units

There are two non pharmacological anti-hypertensive therapies that interrupt sympathetic outflow:

( 1 )device-based carotid baroreflex activation by electrical stimulation of the carotid sinus

(2) endovascular radiofrequency ablation of the renal sympathetic nerves.

Both interventions inhibit sympathetic drive.These are particularly helpful in patients with
"resistant" hypertension and obesity-related hypertension

mc cause of acute pericarditis/constrictive pericarditis/tamponade = idiopathic

mc cause of constrictive pericarditis and tamponade in developing countries = tb.

"BCG vaccine can reverse type 1diabetes"

formula for converting hba1c into plasma sugar in mg/dl = (hba1c * 35.6) - 77.