There are a few indications for penicillin shots these
days, being Syphilis is one of the most frequent indications (intramuscular benzathine G penicillin). Neonatal sepsis due to S agalactiae is another indication where PG salt is used IV intrapartum until delivery
Penicillin G was the first really effective antibiotic,
widely used from 1942, it saved many lives but bacterial resistance developed rapidly maquing it unsuitable to treat most of the current infections.
There are other pecicillins such as Aminopenicillins:
ampicillin and amoxacillin; antipseudomonal penicillins such as piperacillin and antistaphilococcal penicillins such as oxacilin and methicillin. These were developed to overcome resistance, lomited spectrum uf use and oral use limitations. Resistance became a problem too. Bacteria will always develop atb resistance no matter what