around the site of injection (up to 50% of recipients). A small percentage of people develop a mild fever. As with any medication, a small proportion of people develop a severe allergic reaction.[39] In 2016 Health Canada warned of an increased risk of anemia or hemolysis in people treated with eculizumab (Soliris). The highest risk was when individuals "received a dose of Soliris within 2 weeks after being vaccinated with Bexsero".[40]
Despite initial concerns about Guillain-Barré
syndrome, subsequent studies in 2012 have shown no increased risk of GBS after meningococcal conjugate vaccination.[41] [Wikipedia]
There are two types of vaccine, MenACWY and
MenB. The side effects of the MenB vaccine are more severe, but MenB is not given routinely:
In clinical trials the most common adverse events
within 7 days of receiving MenACWY were injection site pain, swelling or redness (44%–59% of recipients). One percent or less of recipients considered the pain to be severe. Other reported symptoms included malaise (11%–22%), and headache (29%–36%). In general adverse events were less frequent following MPSV4 than following MenACWY. Ask the Experts about Meningococcal ACWY Vaccine
In clinical trials the most common adverse events
within 7 days of receiving MenB were injection site pain, swelling or redness (80%%–90% of recipients). Up to 30% of recipients considered the pain to be severe. Other reported symptoms included fatigue (35%–40%), headache (33%%–35%), and myalgia (30%%–49%). In general adverse events were more frequent with the first dose than with subsequent doses.