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What are the possible complications of the

meningococcal vaccine?

It’s a very safe vaccine:

Common side effects include pain and redness


around the site of injection (up to 50% of recipients).
A small percentage of people develop a mild fever.
As with any medication, a small proportion of people
develop a severe allergic reaction.[39] In 2016
Health Canada warned of an increased risk of
anemia or hemolysis in people treated with
eculizumab (Soliris). The highest risk was when
individuals "received a dose of Soliris within 2 weeks
after being vaccinated with Bexsero".[40]

Despite initial concerns about Guillain-Barré


syndrome, subsequent studies in 2012 have shown
no increased risk of GBS after meningococcal
conjugate vaccination.[41] [Wikipedia]

There are two types of vaccine, MenACWY and


MenB. The side effects of the MenB vaccine are
more severe, but MenB is not given routinely:

In clinical trials the most common adverse events


within 7 days of receiving MenACWY were injection
site pain, swelling or redness (44%–59% of
recipients). One percent or less of recipients
considered the pain to be severe. Other reported
symptoms included malaise (11%–22%), and
headache (29%–36%). In general adverse events
were less frequent following MPSV4 than following
MenACWY. Ask the Experts about Meningococcal
ACWY Vaccine

In clinical trials the most common adverse events


within 7 days of receiving MenB were injection site
pain, swelling or redness (80%%–90% of recipients).
Up to 30% of recipients considered the pain to be
severe. Other reported symptoms included fatigue
(35%–40%), headache (33%%–35%), and myalgia
(30%%–49%). In general adverse events were more
frequent with the first dose than with subsequent
doses.

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