Compounding - Wikipedia 4/2/21, 5(36 PM

Compounding
In the field of pharmacy, compounding (performed in
compounding pharmacies) is preparation of a custom
formulation of a medication to fit a unique need of a patient
which cannot be met with commercially available products. This
may be done for medical reasons, such as to be administered by a
different route (ex: tablet to liquid), to avoid a non-active
ingredient that the patient is allergic to, or to provide an exact
dose that isn't commercially available. Medically necessary
compounding is referred to as "traditional" compounding.
Compounding may also be done for medically optional reasons,
such as preference of flavor or texture, or dietary restrictions.

Hospital pharmacies typically engage in compounding

medications for intravenous administration, whereas outpatient
or community pharmacies typically engage in compounding
medications for oral or topical administration. Due to the rising
cost of compounding and drug shortages, some hospitals Pharmacist compounding a
outsource their compounding needs to large-scale compounding medication using a mortar and pestle
pharmacies, particularly of sterile-injectable medications. (c. 1923)

Compounding bulk preparations of a given formulation as

opposed to preparation for a specific patient is known as "non-traditional" compounding. Different
jurisdictions have different rules regarding the applicability of regulations which apply to drug
manufacturers to pharmacies which perform bulk compounding.

Contents
History
Roles
Regulation in Australia
Regulation in the United States
Outsourcing facilities
Drug testing and reporting of incidents
New England Compounding Center incident
Misuse prompting regulatory changes
See also

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