Questions 1.

Lot of options for this answer. As long as there is no resource conflict while using memory.
Note that fetching operand from register does not need memory reference.

Instruction Clock Cycle

1 2 4 5 6 7 8 9 10 11 12 13 14 15 16 17
Load R1,M(25) FI DI FO EI WO

Add R2,R1 FI DI # # FO EI WO
Sub R3,R1 FI DI FO EI WO
Mul R3, R2 FI DI # # FO EI WO
Stor R3,M(45) FI DI # # # # FO EI WO
Question 2.
Question 3.