Professional Documents
Culture Documents
Presented By
Qirtas Tauheed (100-E-14)
Definition:
“Ointments are semi-solid
preparations for
application to the skin.”
Types of Ointments
Medicated ointments
Non-medicated ointments
Medicated ointments
These contain the medicament either dissolved
or dispersed in the vehicle as fine powders or in
the form of micronized powder e.g.
o Gentamicin ointment.
Non medicated ointments
These are used as vehicles for preparation of
medicated ointments or can be used for
their physical effects e.g.
o Soft Paraffin
Properties of ideal ointments
Non sensitizing
Non irritating
Pharmaceutically elegant
Efficient release of medicament at the
site of application
Water -washable
Ointment Bases
Ointment bases are generally classified
by the USP into four groups
I. Oleaginous bases
II. Absorption bases
III. Water removable bases
IV. Water soluble bases
1)Oleaginous bases
Oleaginous bases are also termed as hydrocarbon bases.
On application to the skin
emollient occlusive
effect dressings
- Incorporation
- Fusion
Incorporation
By the incorporation method, the components
are mixed until a uniform preparation is
attained.
Incorporation of solids:
The ointment base is placed on one side of
the working surface and the powdered
components, previously reduced to fine
powders and thoroughly blended in a
mortar, on the other side.
Incorporation of solids
The drug (the pink
powder) is usually the
smaller quantity of the
two ingredients.
oleaginous ointment
hydrophilic base.
2
Pharmaceutical Creams:
Creams are semisolid preparations containing
one or more medical agents dissolved or
dispersed in either an oil-in-water emulsion or
in another type of water-washable base.
Many patients and physicians prefer creams to
ointments because they are easier to spread
and remove than many ointments.