When the respiratory droplets gets into the respiratory system, it will attack the

alveoli specifically the type 2 pneumocytes which is responsible for producing

surfactant that decreases surface tension and reduces collapsing pressure. The
spikes of the virus binds to specific receptor which is the ACE-2 in the type 2
pneumocytes which made the virus be engulfed inside the cell. Then the virus
releases its single stranded RNA in the cytoplasm and uses the host cell's ribosome
which will undergo translation causing it to synthesize more RNA. This will damage
the type 2 pneumocytes, causing it to release an inflammatory mediators which will
stimulate macrophage that will lead to secretion of cytokines. These cytokines will
go to the bloodstream causing the endothelial cells to undergo dilation.Smooth
muscles will dilate and increases the capillary permeability which will lead to
vasodilation and increased capillary permeability. When this happens, all the fluid
and plasma will start leaking in the interstitial spaces and into the alveoli
causing it to be compressed. When the fluid enter the alveoli, this will lead to
alveolar edema. Production of surfactant will be affected, increasing the surfacing
tension that leads to alveolar collapse which will also lead to hypoxemia.

Coronavirus disease (COVID-19) is an infectious disease caused by a newly

discovered coronavirus

when the virus enters the respiratory system, it affects the ventilation syetem of
the human body. it resulats to inadequate gas exchange due to an increase in carbon
dioxide levels and drop in oxygen resulting in an increased work of breathing
leading to a respiratory failure

when you breathe in the same air as someone with tuberculosis and the gets into
your lungs. it will spread to your lymph as well as to the bloodstream. immune
system will be alerted, B cells will make antibodies against it to attack
ktuberculosis. the body will alert the T-cells which are the natural killers to
directly attack tuberculosis. Macrophage will make a perimeter with T- lymphocytes