4/1/2021 CN109730662A - Physiology physical sign monitoring system based on multispectral pulse wave - Google Patents

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Physiology physical sign monitoring system based on multispectral pulse wave

Abstract
CN109730662A
The present invention relates to a kind of physiology physical sign monitoring system based on
China
multispectral pulse wave, the physiology physical sign monitoring system based on multispectral
pulse wave includes hardware components, software section and algorithm part, belongs to
integrated solution ；The hardware components comprise the following modules: control unit, light Download PDF Find Prior Art Similar
source unit, light signal collection unit, processing unit, wireless transmission unit, power supply
unit；The light source unit supports the light source of at least four wave band；The processing Other languages: Chinese
；The wireless transmission unit can be transmitted for Bluetooth
unit is used for signal processing
姜红, 王⽂锦
transmission or WIFI；The power supply unit is battery or rechargeable；The physical signs that the
Inventor:

software section calculates includes heart rate and heart rate variability；Respiratory rate；Blood
oxygen saturation；Blood pressure/blood pressure.Its advantage is shown: can be applicable to can Worldwide applications
pass through multispectral pulse wave signal and monitor multiple physical signs simultaneously,
；
and provide clinical meaning in portable wearable device Enhance the stability and robustness of
2019 CN

single physical signs monitoring.

Application CN201910213390.3A events

2019-03-20 Application led by 复旦⼤学附属中⼭医院

2019-03-20 Priority to CN201910213390.3A

2019-05-10 Publication of CN109730662A

Info: Cited by (1), Legal events, Similar documents, Priority and

Related Applications

External links: Espacenet, Global Dossier, Discuss

Claims (3) Hide Dependent

1. a kind of physiology physical sign monitoring system based on multispectral pulse wave, which is characterized in that described based on multispectral pulse The physiology
physical sign monitoring system of wave includes hardware components, software section and algorithm part ；The hardware components include: that control is single
；The light source unit is supported The light source of at
Member, light source unit, light signal collection unit, processing unit, wireless transmission unit, power supply unit
least four wave band；The processing unit is used for signal processing；The wireless transmission unit be Bluetooth transmission or WIFI transmission；The power supply
unit is battery or rechargeable.

2. the physiology physical sign monitoring system according to claim 1 based on multispectral pulse wave, which is characterized in that described The light source unit
；The light of different-waveband Source successively emits optical
of control unit timing control different-waveband, while including visible light and black light part
；
signal, and light signal collection unit successively acquires optical signal, and is sent to processing unit Processing unit believes light It number is handled, control unit
is transmitted to after processing, the result of processing is transmitted to terminal outward by wireless transmission and set by control unit It is standby；Wherein,
processing unit can directly extract physical signs and be sent to terminal, or carries out simple Signal Pretreatment and be then forwarded to end Extract physical signs
in end.

3. the physiology physical sign monitoring system according to claim 1 based on multispectral pulse wave, which is characterized in that described soft The correlated
characteristic of the physical signs that part part calculates, required wave band and calculating is as follows:

；PPG signal frequency domain [40,240] hertz peak detection；

Heart rate and heart rate variability: blue light, green light band

Respiratory rate: blue light, green light band；PPG signal frequency domain [15,50] hertz peak detection；

Blood oxygen saturation: feux rouges, infrared band；The variation detection of PPG signal Time Domain Amplitude；

Blood pressure/blood pressure: blue light, infrared band；PPG signal time domain phase difference detection.

Description

Physiology physical sign monitoring system based on multispectral pulse wave

Technical eld

The present invention relates to multispectral technical elds, speci cally, being a kind of physiology sign prison based on multispectral pulse wave Examining system.

Background technique

As China enters the aging society stage gradually, all kinds of Aging Problems are constantly highlighted, the health of the aged Problem is exactly wherein one of urgent
problem to be solved.Gradually due to patient populations dead because suffering from blood vessel tubing disease every year Rise, has become the whole society, in

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4/1/2021 CN109730662A - Physiology physical sign monitoring system based on multispectral pulse wave - Google Patents
particular for the great public health problem of the elderly.Thus, in order to realize painstaking effort The prevention and adjuvant treatment of tubing disease, there is an
urgent need to carry out continuous monitoring to physiologic informations such as pulse, blood pressure and electrocardios.

Currently used and more mature wearable physiology continuous monitoring product is mostly two classes: (1) motion bracelet, By single green band, come monitor
；
heart rate signal, (green light band PPG signal is strong, can reach certain motion robustness, but supervise The physical signs of survey is excessively single) (2) nger
oximeters are saturated by red and infrared double-waveband come monitor heart rate and blood oxygen It spends (infrared band PPG signal is weak, therefore rhythm of
the heart stability is lower).

Chinese patent literature: CN201710805700.1, applying date 2017.09.08, patent name are as follows: be based on PPG pulse Monitoring of blood pressure sensor chip of
wave and preparation method thereof.Disclose a kind of monitoring of blood pressure sensor core based on PPG pulse wave Piece and preparation method thereof
comprising: substrate, the exible media layer being arranged on substrate, the drain-source being arranged on exible media layer Electrode, gate electrode and
electrocardio measuring electrode, drain-source electrodes, gate electrode and electrocardio measuring electrode are respectively positioned on exible media layer On ；
The active layer being arranged on the interdigitated region of drain-source electrodes, on active layer and is not covered on the region of active layer The protective layer
of setting.

Chinese patent literature: CN201610599137.2, applying date 2016.07.27, patent name are as follows: a kind of optics is swept Retouch formula pulse wave sensor and
wearable device.Disclose a kind of optical scanner formula pulse wave sensor and wearable device, light Learn scan-type wrist type pulse wave analyzer, optical scanner
formula heart rate monitor, optical scanner formula blood pressure monitor, optical scanner formula blood vessel Hardness analyzer, optical scanner formula carotid
；
artery stiffness analyzer and pulse wave monitoring method.The pulse wave sensor includes laser Transmitter emits rst laser Branch optical waveguide component,
；Light draws Output block is led, receive and adjusts second laser to form third laser, third laser is
receives rst laser and branch is second laser and reference light
enable to be incident on blood vessel；Light guidance is defeated Enter component, receive and adjusts the 4th laser from vasore ex to form the 5th laser；Receiving
light path component receives the 5th laser The 6th laser is formed after two-way is interfered with reference light.

A kind of monitoring of blood pressure sensor chip and preparation method thereof based on PPG pulse wave of above patent document, blood pressure Monitor sensor
chip can long-term seamless applying human body, while measuring electrocardiosignal and pulse wave of multiple points, realize noninvasive company Continuous
monitoring of blood pressure, and preparation method simpli es preparation process using the whirl coating technique and inkjet printing technology of low cost ；And it
is special One of sharp document CN201610599137.2 optical scanner formula pulse wave sensor and wearable device, the then one kind provided Optical scanner
formula pulse wave sensor, related monitoring device and wearable device are able to achieve continuous monitoring, and accuracy is high, effect is good And it is low in
energy consumption.But a variety of different physical signs can be monitored by different light source wave bands simultaneously about a kind of, and enhance single
The stability and robustness of a physical signs monitoring, and have and a kind of physiology based on multispectral pulse wave of clinical meaning is provided Physical
sign monitoring system is at present then without relevant report.

In conclusion needing a kind of by different light source wave bands, a variety of different physical signs can be monitored simultaneously, and increase The stability and
robustness of strong single physical signs monitoring, and have and a kind of based on multispectral pulse wave of clinical meaning is provided Physiology physical sign
monitoring system.

Summary of the invention

It is a kind of by different light source wave bands the purpose of the present invention is aiming at the shortcomings in the prior art, providing, it can be simultaneously A
variety of different physical signs are monitored, and enhance the stability and robustness of single physical signs monitoring, and have and clinic is provided A kind of
physiology physical sign monitoring system based on multispectral pulse wave of meaning.

To achieve the above object, the technical solution adopted by the present invention is that:

A kind of physiology physical sign monitoring system based on multispectral pulse wave, which is characterized in that described based on multispectral arteries and
veins The physiology physical sign monitoring system of wave of ghting includes hardware components, software section and algorithm part The hardware；
components include: control Unit, light source unit, light signal collection unit, processing unit, wireless transmission unit, power supply unit ；The light source unit branch
； ；
Hold the light source of at least four wave band The processing unit is used for signal processing The wireless transmission unit be Bluetooth transmission or WIFI
transmission ；The power supply unit is battery or rechargeable.
As a kind of perferred technical scheme, the light source unit of the control unit timing control different-waveband, simultaneously Including visible light and black light
part；The light source of different-waveband successively emits optical signal, and light signal collection unit successively acquires Optical signal, and it is sent to
processing unit；Processing unit handles optical signal, and control unit, control unit are transmitted to after processing The result of processing is transmitted to
terminal device by wireless transmission outward；Wherein, processing unit can directly extract physical signs transmission To terminal, or carries out simple Signal
Pretreatment and be then forwarded to terminal extraction physical signs.

As a kind of perferred technical scheme, the physical signs that the software section calculates, required wave band and calculating Correlated characteristic is as
follows:

；PPG signal frequency domain [40,240] hertz peak detection；

Heart rate and heart rate variability: blue light, green light band

Respiratory rate: blue light, green light band；PPG signal frequency domain [15,50] hertz peak detection；

Blood oxygen saturation: feux rouges, infrared band；The variation detection of PPG signal Time Domain Amplitude；

Blood pressure/blood pressure: blue light, infrared band；PPG signal time domain phase difference detection.

The invention has the advantages that:

1, by different light source wave bands, a variety of different physical signs can be monitored simultaneously.

2, enhance the stability and robustness of single physical signs monitoring.

3, it can be applied in portable wearable device, multiple physical signs monitored simultaneously by multispectral pulse wave signal, And provide clinical meaning.

Detailed description of the invention

Attached drawing 1 is a kind of structural representation of the physiology physical sign monitoring system hardware components based on multispectral pulse wave of
the present invention Figure.

Speci c embodiment

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4/1/2021 CN109730662A - Physiology physical sign monitoring system based on multispectral pulse wave - Google Patents
It elaborates with reference to the accompanying drawing to speci c embodiment provided by the invention.

Before illustrating the present invention, rst illustrate the cardinal principle and thought of the present invention herein:

Multispectral photoplethysmographic (Multi-wavelength Photoplethysmography) can supervise simultaneously Survey the pulse wave signal (PPG) under different light
source wave bands ；The pulse wave of different-waveband can re ect different human body physiological characteristics, As the heart rate signal of green light band is
；
most strong but to the variation of blood oxygen it is insensitive, infrared band is sensitive to the variation of blood oxygen but heart rate is believed It is number faint
Therefore, PPG signal is extracted jointly under (visible light and black light) under multiple wave bands to be of great importance；It can be Different physical signs is
obtained under different-waveband, and can speculate more physiological characteristics in conjunction with the PPG signal of different-waveband, The transmission
time (Pulse Transit Time) of pulse wave, Jin Erji are such as speculated by the PPG signal under blue light and infrared light Calculate blood pressure ；
Physiological characteristic based on multispectral pulse wave detects feature are as follows: the physical signs monitoring (7 of wearable continuous non-invasive It/24
hours) ；It can monitor a variety of physical signs, such as heart rate simultaneously, heart rate variability, respiratory rate, blood oxygen saturation, blood pressure/ Blood
pressure, etc. ；
Multiple physical signs based on monitoring carry out intelligence in conjunction with arti cial intelligence (machine learning/pattern-recognition/big data) Diagnosis and
alarm, such as predict different sleep stages by two indexs of heart rate variability and respiratory rate ；
As monitoring side, the physiological status (forming personalized log) of long-term follow patient assists diagnosis and design Targeted therapeutic scheme, or
input/foundation is provided for therapeutic intervention equipment ；
The technology is suitable for following scene:

Professional medical equipment ；Long-continued physiology monitoring and report, such as cardiovascular disease, the heart are carried out for certain class patient
Pulmonary dysfunction/rehabilitation, hypertension, insomnia, OSAS, diabetes, Intensive Care Therapy (ICU), neonatal care (NICU), etc.；
Domestic healthy equipment ；There is provided physiology monitoring for certain class special population or under special scenes, as the elderly (prevention, Early
warning), sub-health population, pilot/astronaut training (psychology/mood monitoring and management), training athlete/rehabilitation, security protection Field
(portable wearable a lie detector), cardiovascular disease, cardio-pulmonary function impaired patients follow-up, or have the group of related needs ；
Attached drawing 1 is please referred to, Fig. 1 is a kind of physiology physical sign monitoring system hardware components based on multispectral pulse wave of the
present invention Structural schematic diagram.A kind of physiology physical sign monitoring system based on multispectral pulse wave, it is described based on
multispectral pulse wave Physiology physical sign monitoring system includes hardware components, software section and algorithm part, belongs to integrated
；The hardware Part comprises the following modules: control unit, light source unit, light signal collection unit, processing unit, wireless transmission unit,
solution
power supply Unit ；The light source unit supports the light source of at least four wave band；The processing unit is used for signal processing；The nothing Line
transmission unit can transmit for Bluetooth transmission or WIFI；The power supply unit is battery or rechargeable；

The groundwork process of the hardware components are as follows: (1) light source unit of control unit timing control different-waveband is (same When include visible
light and black light part), the light source of (2) different-waveband successively emits optical signal, light signal collection unit according to Secondary acquisition
optical signal, and it is sent to processing unit, (3) processing unit handles optical signal, control unit is transmitted to after processing, The result of processing is
；
transmitted to terminal device by being wirelessly transferred (bluetooth or WIFI) by control unit outward Wherein, processing unit can Directly extract physical signs
and be sent to terminal, or carry out simple Signal Pretreatment be then forwarded to terminal extract physical signs (can Undertake higher computation complexity) ；
The correlated characteristic of the physical signs that the software section calculates, required wave band and calculating is as follows:

Heart rate and heart rate variability: blue light, green light band.PPG signal frequency domain [40,240] hertz peak detection ；
；
Respiratory rate: blue light, green light band PPG signal frequency domain [15,50] hertz peak detection ；
Blood oxygen saturation: feux rouges, infrared band ；The variation detection of PPG signal Time Domain Amplitude；
Blood pressure/blood pressure: blue light, infrared band；PPG signal time domain phase difference detection；

It should be understood that mainly being had using the reason of multispectral detection pulse wave: (1) since the light of different wave length penetrates The depth of
skin is different, and the PPG signal acquired under different-waveband can re ect the information of different depth vescular bed ；Such as blue light (470nm) re ection
be shallow-layer vein blood vessel information, and infrared (940nm) re ection be deep artery blood vessel information, this The PPG signal phase difference in time of
acquisition simultaneously under two wave bands ；Therefore, the PPG signal meter under blue light and infrared light can be used The transmission time of pulse wave
；
is calculated, and then derives velocity of blood ow, blood pressure or even pressure value (needing baseline calibration) (2) blood Hemoglobin is different to the
absorption of the light of different-waveband in liquid, the light of the oxygen content (HbO2, Hb) of hemoglobin to different-waveband Sensibility it is also different；
Pulse such as green light (570nm) wave band is most strong to the absorption of light, and red (660nm) and infrared (940nm) changes blood oxygen most
sensitive.Therefore different physical signs can be obtained simultaneously in conjunction with the PPG signal of different-waveband ； (3) it when calculating physical
signs, can also mutually be supported between the PPG signal of different-waveband, it is common to cooperate, it is such as full in calculating blood oxygen Noise
reduction is ltered to infrared PPG signal (signal is weaker) with blue light/green light PPG signal (signal is stronger) with when spending, is enhanced Correlated
characteristic.

Physiology sign detection system based on multispectral pulse wave of the invention can be simultaneously by different light source wave bands Monitor a variety of
different physical signs ；Enhance the stability and robustness of single physical signs monitoring；This monitoring system can be applied In in portable wearable
device, multiple physical signs are monitored simultaneously by multispectral pulse wave signal, and provide clinical meaning.

The above is only a preferred embodiment of the present invention, it is noted that for the ordinary skill people of the art Member, under the premise of not departing from
the method for the present invention, can also make several improvement and supplement, these are improved and supplement also should be regarded as Protection
scope of the present invention.

Cited By (1)

Publication number Priority date Publication date Assignee Title

CN110251094A * 2019-05-14 2019-09-20 周常安 Finger-worn type physiology detection apparatus

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* Cited by examiner, † Cited by third party, ‡ Family to family citation

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Priority And Related Applications

Priority Applications (1)

Application Priority date Filing date Title

CN201910213390.3A 2019-03-20 2019-03-20 Physiology physical sign monitoring system based on multispectral pulse wave

Applications Claiming Priority (1)

Application Filing date Title

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Legal Events

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Date Code Title Description

2019-05-10 PB01 Publication

2019-05-10 PB01 Publication

2019-06-04 SE01 Entry into force of request for substantive examination

2019-06-04 SE01 Entry into force of request for substantive examination

2019-10-29 EE01 Entry into force of recordation of patent licensing contract

2019-10-29 EE01 Entry into force of recordation of patent licensing contract Application publication date: 20190510

Assignee: Perth Sleep Technology (Shenzhen) Co., Ltd.

Assignor: Zhongshan Hospital A liated to Fudan University

Contract record no.: X2019980000225

Denomination of invention: Physiological sign monitoring system based on multispectral

pulse wave

License type: Exclusive License

Record date: 20190930

Concepts

machine-extracted Download Filter table

Name Image Sections Count Query match

physiological effects, processes and functions title,claims,abstract,description 22 0.000

biological transmission claims,abstract,description 19 0.000

blood pressure claims,abstract,description 19 0.000

Blood claims,abstract,description 11 0.000

blood claims,abstract,description 11 0.000

oxygen claims,abstract,description 11 0.000

O O

oxygen claims,abstract,description 11 0.000

oxygen claims,abstract,description 11 0.000

respiratory rate claims,abstract,description 6 0.000

Polypropylene glycol claims,description 28 0.000

optical claims,description 16 0.000

correlated claims,description 4 0.000

enhancing abstract,description 5 0.000

Show all concepts from the description section

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