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4.5.3 Cholesterol Balance - 4.5 Lipid Metabolism - NUTR101x Courseware - Edx
4.5.3 Cholesterol Balance - 4.5 Lipid Metabolism - NUTR101x Courseware - Edx
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Cholesterol balance
Cholesterol has a number of functions in the body. First, cholesterol is needed to make bile acids, which in turn are required for e cient
digestion of dietary fats. Second, cholesterol is used to make several (steroid) hormones such as the male and female sex hormones. Third,
cholesterol is a component of cell membranes. It is important to realize that cholesterol is not a nutrient because our own cells can make
cholesterol. Only approximately one-third of the cholesterol in our bodies comes from our diet. The rest is synthesized in the body. For this
reason, we can subsist on a diet that is completely devoid of cholesterol.
The cholesterol in the diet and the cholesterol produced in our body together comprise the cholesterol input. Cholesterol leaves the body in the
feces in the form of cholesterol that was excreted as part of bile, or in the form of bile acids that were made from cholesterol. Disturbances in
bile acid metabolism can in uence cholesterol metabolism and vice versa.
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