After we sin, sometimes the guilt is so tremendous, it eventually drives us insane.
But what physiological effects does guilt produce? The first effect is deprivation of sleep. Matthew 11:28 says “Come to me, all of you who are tired and are carrying heavy loads. I will give you rest.” Our body needs sleep and it is a gift from God, who gives it freely. Yet in Macbeth, after they kill Duncan, both Macbeth and Lady Macbeth have trouble sleeping. He heard a voice saying “Sleep no more; Macbeth shall sleep no more.” Without sleep, we have a sick mind. When they are able to sleep, they have horrible nightmares. Lady Macbeth sleepwalks, imagining that she is washing off blood of her hands. This depicts that she thought she could rid the guilt with water. Another effect is regret. At the start of the play, they are confident, but towards the end they are haunted with guilt. They wish they didn’t kill him in the first place. He has committed more than one murder and cannot forget it. Another effect of sin is a seared conscience. After you sin once, it is easy to do it again. Macbeth feels that there is no turning back now that I’m halfway there. He thinks that he will never be forgiven for his crimes. Yet God forgives and forgets even the most revolting sins when we repent.