DRUG STUDY

DRUG DRUG INDICATIONS/CONTRAINDICAT DOSAGES AND ADVERSE REACTIONS NURSING RESPONSIBILITIES

NAME CLASSIFICATI IONS ADMINISTARTI
ON ON
GENERIC Antidiabetic It is use for; DOSAGES GIVEN METABOLIC: 1. Assess patient’s glucose
NAME:  Moderate to severe diabetic TO THE hyperglycemia, hypoglycemia level before starting therapy
insulin ketoacidosis or hyperosmolar PATIENT: and regularly thereafter.
(regular) hyperglycemia 1. Regular Insulin RESPIRATORY: dyspnea, 2. Monitor patients
 Mild diabetic acidosis 6 units SQ now increased cough, reduced glycosylated hemoglobin
BRAND  Newly diagnosed diabetes 2. Regular Insulin pulmonary function, level regularly.
NAME: mellitus 8 units SQ now respiratory tract infection 3. Monitor urine ketone level
Humulin R,  Control of hyperglycemia with 3. Insulin 70/30 when glucose level is
Novolin R Humalog and longer acting SQ Q12 SKIN: elevated.
insulin in patients with type 1  12 units Rash, redness, stinging, 4. Monitor injection site for
diabetes mellitus SQ pre swelling, urticarial, warmth at local reactions.
 Hyperkalemia breakfast injection site 5. Be alert for adverse reaction
 14 units 6. Assess patients and family’s
Contraindications: SQ pre OTHER: anaphylaxis, knowledge about the
 Contraindicated in dinner hypersensitivity reaction, therapy.
hypoglycemia and in patients lipoatrophy, lipohypertrophy, 7. Always spell out “units” to
hypersensitive to insulin or rash reduce the risk of
any of its ingredients. misreading “u” as a zero.
8. Tell patient that insulin
relieves symptoms but
doesn’t cure disease.
9. Advise patient not to alter
order of mixing insulins or
change or brand of syringe
or needle.
10. Instruct patient not to drink
alcohol and smoke during
therapy.
 DRUG DRUG INDICATIONS/CONTRAINDICAT DOSAGES AND ADVERSE REACTIONS NURSING RESPONSIBILITIES
NAME CLASSIFICATI IONS ADMINISTARTI
ON ON
GENERIC Antihypertensive It is use for; Clonidine 75 mcg 1 CNS: anxiety, confusion, 1. Assess patient blood
NAME:  Essential, renal and malignant tab SL now dizziness, fatigue, headache, pressure before therapy and
Clonidine hypertension nervousness, sedation, regularly thereafter.
hydrochlori  Severe pain somnolence, vivid dreams 2. Antihypertensive effects of
de  Prophylaxis for vascular transdermal clonidine may
headache CV: bradycardia, take 2 to 3 days to become
BRAND  Adjunctive therapy for hypotension, orthostatic apparent.
NAME: nicotine withdrawal hypotension, severe rebound 3. Be alert for adverse
Catapres  Adjunct in opioid withdrawal hypertension reactions.
 Dysmenorrhea 4. Periodic eye examination
GI: constipation, dry mouth, are recommended.
 Ulcerative colitis
nausea, vomiting 5. Assess patient about
 Diabetic diarrhea
pruritus.
Contraindications: SKIN: pruritus asnd 6. Monitor patient closely,
dermatitis especially during the few
 Contraindicated to patient
sensitive to the drugs first few days of the therapy.
METABOLIC: Respiratory depression or
 Use cautiously to patient with
Transient glucose intolerance deep sedation may occur.
severe coronary insufficiency,
recent MI, cerebrovascular
disease, and chronic or renal
impairment
 DRUG DRUG INDICATIONS/CONTRAINDICAT DOSAGES AND ADVERSE REACTIONS NURSING RESPONSIBILITIES
NAME CLASSIFICATI IONS ADMINISTARTI
ON ON
GENERIC Antianginal, It is use for; 10 mg tab, 1 tab in CNS: fatigue, headache, 1. Assess patient’s blood
NAME: Antihypertensive  Chronic stable angina PM somnolence pressure or angina before
Amlodipine  Hypertension therapy and regularly
besylate CV: dizziness, edema, thereafter.
Contraindications: flushing, palpitations 2. Monitor patient carefully
BRAND  Contraindicated in patients for pain.
NAME: hypersensitive to drugs GI: abdominal pain, 3. Be alert for adverse effects.
Norvasc  Used cautiously in patient dyspepsia, nausea 4. Give S.L. nitroglycerin as
taking other peripheral needed for acute angina.
vasodilators and in those with 5. Advise patient to continue
heart failure taking drug even when
 In patients with severe hepatic feeling better.
disease
 DRUG DRUG INDICATIONS/CONTRAINDICAT DOSAGES AND ADVERSE REACTIONS NURSING RESPONSIBILITIES
NAME CLASSIFICATI IONS ADMINISTARTI
ON ON
GENERIC Antidiabetic Uses: 500 mg, 1 tab BID CNS: Headache, dizziness, 1. Lab tests: Obtain baseline
NAME: agitation, fatigue. and
metformin  Metformin is used together periodic kidney and liver fu
hydrochlori with diet and exercise to nction tests; drug
de improve blood sugar control in contraindicated in the
adults with type 2 diabetes presence of renal or hepatic
BRAND mellitus. insufficiency.
NAME: 2. Monitor blood glucose and
Fortamet  Metformin is sometimes used HbA1C, and lipid profile
together with insulin or other periodically.
medications, but it is not for 3. Monitor known or suspected
treating type 1 diabetes. alcoholics carefully for
decreased liver function.
4. Monitor cardiopulmonary
Contraindications:
status throughout course of
 Hypersensitivity to
therapy; cardiopulmonary
metformin; renal, hepatic, or
insufficiency may
cardiopulmonary
predispose to lactic acidosis.
insufficiency; alcoholism;
5. Be aware
concurrent infection.
that hypoglycemia is not a
risk when drug is taken in
recommended therapeutic
doses unless combined with
other drugs which lower
blood glucose.
6. Report to physician
immediately S&S of
infection, which increase the
risk of lactic acidosis (e.g.,
abdominal pains, nausea and
vomiting anorexia).
7. Do not breast feed while
taking this drug without
consulting physician.
 DRUG DRUG INDICATIONS/CONTRAINDICAT DOSAGES AND ADVERSE REACTIONS NURSING RESPONSIBILITIES
NAME CLASSIFICATI IONS ADMINISTARTI
ON ON
GENERIC Antilipemic Uses: 20 mg 1 tab OD HS CNS: asthenia, fever, 1. Monitor patient’s liver
NAME: headache, malaise function and lipid level at
atorvastatin  Atorvastatin is used together baseline and periodically
with diet to lower blood levels CV: chest pain after.
BRAND of "bad" cholesterol (low- 2. Monitor patient for signs of
NAME: density lipoprotein, or LDL), EENT: pharyngitis, sinusitis rhabdomyolysis, especially
Lipitor to increase levels of "good" if taking more than one class
cholesterol (high-density GI: abdominal pain, of lipid lowering drugs.
lipoprotein, or HDL), and to constipation, diarrhea, 3. Use drug only after diet and
lower triglycerides (a type of dyspepsia, flatulence other non-drug treatments
fat in the blood). prove ineffective. Patient
MUSCULUSKELETAL: should follow a low
 Atorvastatin is used to arthralgia, myalgia, back pain cholesterol diet before and
treat high cholesterol, and to during therapy.
lower the risk of stroke, heart SKIN: rash, erythema 4. Check CK level if patient
attack, or other heart multiform, Stevens Johnson complains of muscle pain,
complications in people with Syndrome, toxic epidermal tenderness or weakness.
type 2 diabetes, coronary heart necrolysis 5. Obtain liver function test
disease, or other risk factors. results and lipid levels
OTHER: accidental injury, before therapy, after 6 and
angioedema, flulike 12weeks, after a dosage
 Atorvastatin is used in adults syndrome, hypersensitivity increase and periodically
and children who are at least reaction infection thereafter.
10 years old.

Contraindications:
 Do not use if you have liver
disease
 Do not use if you are pregnant.
Stop taking this medicine and
tell your doctor right away if
you become pregnant.
 Do not breastfeed while you
are taking this medicine.
  Atorvastatin can cause a
condition that results in the
breakdown of skeletal muscle
tissue, potentially leading to
kidney failure.
 Atorvastatin is not approved
for use by anyone younger
than 10 years old.

DRUG DRUG INDICATIONS/CONTRAINDICAT DOSAGES AND ADVERSE REACTIONS NURSING RESPONSIBILITIES

NAME CLASSIFICATI IONS ADMINISTARTI
ON ON
GENERIC Antibiotic It is used for; 1.5 gm IV Q8 CV: thrombophlebitis, vein 1. Obtain history of infections
NAME:  Susceptible infections ANST (-) irritation before therapy and observe
ampicillin +  Uncomplicated gonorrhea throughout therapy.
sulbactam  Intra-abdominal infections, GI: diarrhea, glossitis, 2. Ask patient about previous
respiratory tract infections and nausea, stomatitis and allergic reaction to
BRAND urinary tract infections vomiting penicillin.
NAME:  Skin and skin structure 3. Obtain the skin testing
Unasyn infections HEMATOLOGIC: before giving the first dose.
agranulocytosis, anemia, 4. Monitor for the patient
Contraindications: eosinophilia, leukopenia, hydration status if adverse
 Hypersensitivity to ampicillin, thrombocytopenia, GI reactions occur.
sulbactam or other β-lactam thrombocytopenic purpura 5. In patient with renal
antibacterials (e.g. penicillins, impairment, dosage should
cephalosporins). OTHER: anaphylaxis, be reduced.
 History of cholestatic erythematous maculopapular 6. Stop drug immediately if
jaundice/hepatic dysfunction rash, urticarial, overgrowth of anaphylaxis occurs.
associated w/ ampicillin and no susceptible organisms, 7. Tell patient to call prescriber
sulbactam. pain at injection site if rash, fever or chill
 Patient w/ infectious develop.
mononucleosis. Hepatic and
renal impairment. Pregnancy
and lactation.
 DRUG DRUG INDICATIONS/CONTRAINDICAT DOSAGES AND ADVERSE REACTIONS NURSING RESPONSIBILITIES
NAME CLASSIFICATI IONS ADMINISTARTI
ON ON
GENERIC Antipyretic, Uses:  500 mg  Minimal GI upset. 1. Do not exceed
NAME: Analgesics  Control of pain due to tab, 1-tab  Methemoglobinemia 4gm/24hr. in adults and
paracetamo headache, earache, PRN  Hemolytic Anemia 75mg/kg/day in
l dysmenorrhea, arthralgia,  300 mg IV  Neutropenia children.
myalgia, musculoskeletal PRN  Thrombocytopenia 2. Do not take for >5days
BRAND pain, arthritis, immunizations,  Pancytopenia for pain in children, 10
NAME: teething, tonsillectomy days for pain in adults,
 Leukopenia
Biogesic,  O reduce fever in viral and  Urticaria
or more than 3 days for
Tylenol, bacterial infections fever in adults.
 CNS stimulation
Panadol  As a substitute for aspirin in 3. Extended-Release
 Hypoglycemic coma tablets are not to be
upper GI disease, bleeding
 Jaundice chewed.
disorders clients in
 Glissitis 4. Monitor CBC, liver and
anticoagulant therapy and
gouty arthritis  Drowsiness renal functions.
 Liver Damage 5. Assess for fecal occult
Contraindications: blood and nephritis.
 Renal insufficiency 6. Avoid using OTC drugs
 Anemia with Acetaminophen.
 Liver toxicity (hepatocyte 7. Take with food or milk
necrosis) may occur with to minimize GI upset.
doses not far beyond labeled 8. Report N&V. cyanosis,
dosing. shortness of breath and
abdominal pain as these
 If 3 or more alcoholic drinks
are signs of toxicity.
per day are consumed, consult
a physician prior to use. 9. Report abdominal pain,
jaundice, dark urine,
itchiness or clay-colored
stools.
10. Report pain that persists
for more than 3-5 days
11. Avoid alcohol.
12. This drug is not for
regular use with any
form of liver disease.
 DRUG DRUG INDICATIONS/CONTRAINDICAT DOSAGES AND ADVERSE REACTIONS NURSING RESPONSIBILITIES
NAME CLASSIFICATI IONS ADMINISTARTI
ON ON
GENERIC Antihypertensive It is used for; 50 mg tab, 1 tab For hypertension and left 1. Assess patients’ blood
NAME:  Hypertension OD in AM ventricular hypertrophy: pressure before starting
losartan  Nephropathy in type 2 therapy.
potassium diabetes mellitus CNS: asthenia, fatigue, 2. Regularly assess creatinine
 To reduce risks of strokes in headache, dizziness and BUN levels to check
BRAND patient with hypertension and kidney failure.
NAME: left ventricular hypertension CV: chest pain, edema 3. If patient is takin a diuretic,
Cozaar watch for symptomatic
Contraindications: EENT: sinusitis, pharyngitis, hypotension.
 Do not use if you have liver sinus disorder 4. Give once daily dose in the
disease morning to prevent
 Do not use if you are pregnant. GI: abdominal pain, diarrhea, insomnia.
Stop taking this medicine and dyspepsia, nausea
tell your doctor right away if
you become pregnant. MUSKULOSKELETAL:
muscle cramps, myalgia

RESPIRATORY: cough,
upper respiratory infection

OTHER: anaphylaxis,
angioedema

For nephropathy:

CNS: asthenia, diabetic

neuropathy, fatigue, fever

CV: chest pain, hypotension,

orthostatic hypotension

EENT: cataract, sinusitis

GI: diarrhea, dyspepsia,
gastritis

GU: UTI
HEMATOLOGIC: anemia

METABOLIC:
hyperkalemia, hypoglycemia,
weight gain

MUSKUSKELETAL:
Back pain, muscle weakness

RESPIRATORY: bronchitis,
cough

SKIN: cellulitis

OTHER: anaphylaxis,
angioedema
 DRUG DRUG INDICATIONS/CONTRAINDICAT DOSAGES AND ADVERSE REACTIONS NURSING RESPONSIBILITIES
NAME CLASSIFICATI IONS ADMINISTARTI
ON ON
GENERIC Antiplatelet, It is used for: 80 mg tab, 1 tab GASTROINTESTINAL:  Check and verify with
NAME: Analgesics, OD PC in lunch nausea, dyspepsia, heartburn, doctor’s order and
Antipyretic  Mild to moderate pain epigastric discomfort, Kardex.
aspirin anorexia, hepatotoxicity  Observe rights
 Fever in medication administr
HEMATOLOGIC: ation such as giving the
 Inflammatory conditions occult blood loss, hemostatic right drug to the right
BRAND such as rheumatic fever, defects patient using the right
NAME: arthritis, and HYPERSENSITIVITY: route and at the right
spondyloarthropaties anaphylactoid reactions to time.
Aspergum, anaphylactic shock  Assess skin color and
Bayer,  Reduction of risk of presence of lesions as
Ecotrin recurrent transient SALICYLISM: dizziness, this may indicate
ischemic attack (precursor tinnitus, difficulty hearing, hepatotoxicity, allergy,
to stroke) nausea, vomiting, diarrhea, bleeding, and other
or cardiovascular accident mental confusion complications.
(stroke) in patients with  Assess patient’s
history of TIA due to orientation to time and
fibrin platelet emboli or place as the drug may
ischemic stroke cause dizziness and
confusion.
 Unlabeled use:  Give drug with food or
prophylaxis against after meal if GI upset
cataract formation with occurs.
long-term use  To reduce the risk of the
tablet lodging in the
esophagus, give drug
with full glass of water.
Contraindications:  Ensure that patient does
not crush and chew
 People with allergy to tablets as well as
salicylates or NSAIDs. sustained release
This is more common to preparations to prevent
people with nasal losing drug’s effectivity.
 polyps, asthma, and  If aspirin has vinegar-
chronic urticaria. like odor, do not use and
dispose.
 People with haemophilia,  In case of overdose,
allergy to tartrazine (cross- institute emergency
sensitivity is common), procedures and prepare
bleeding ulcers, blood equipment for gastric
coagulation defects, and lavage, induction of
with Vitamin K deficiency emesis, and activated
(increased risk of charcoal.
bleeding)  Continue monitoring
clotting factors,
 Caution with people who bleeding time, liver and
have impaired renal renal function tests for
function, children and long-term drug therapy.
teenagers (risk for  Observe patient for
developing Reye’s signs and symptoms of
Syndrome), patients who bleeding such as easy
will have surgery within 1 bruising, bleeding in the
week, and pregnant gums, and nosebleeds.
women (it readily crosses  Monitor vital signs.
placenta and is a possible  Raise side rails up to
teratogen) as well as ensure patient’s safety.
lactating mothers.  Monitor for signs and
symptoms of drug
allergy such as difficulty
of breathing, pruritus,
and rashes.
 Provide a room
environment conducive
for resting.
 DRUG DRUG INDICATIONS/CONTRAINDICAT DOSAGES AND ADVERSE REACTIONS NURSING RESPONSIBILITIES
NAME CLASSIFICATI IONS ADMINISTARTI
ON ON
GENERIC Antihypertensive It is used for:  25 mg tab,  a light-headed  WARNING: Do not
NAME:  Hypertension 1 tab OD feeling, like you discontinue drug abruptly
carvedilol  Angina pectoris in PM might pass out; after chronic therapy
 Heart failure  12.5 mg  slow or uneven (hypersensitivity to
BRAND  Left ventricular dysfunction tab, 1 tab heartbeats; catecholamine may have
NAME: post myocardial infection BID  swelling, rapid developed, causing
Coreg weight gain, feeling exacerbation of angina, MI,
Contraindications: short of breath (even and ventricular
 Hypersensitivity; severe with mild exertion); arrhythmias); taper drug
chronic heart failure, bronchial  cold feeling or gradually over 2 weeks with
asthma or related numbness in your monitoring.
bronchospastic conditions; fingers or toes;  Consult with physician
severe hepatic impairment.  chest pain, dry about withdrawing drug if
 Patients with NYHA class IV cough, wheezing, patient is to undergo surgery
cardiac failure, 2nd or 3rd ° chest tightness, (withdrawal is
AV block, sick sinus trouble breathing; or controversial).
syndrome (unless a permanent  high blood sugar  Give with food to decrease
pacemaker is in place), (increased thirst, orthostatic hypotension and
cardiogenic shock or severe increased urination, adverse effects.
bradycardia. hunger, dry mouth,  Monitor for orthostatic
 Lactation fruity breath odor, hypotension and provide
drowsiness, dry skin, safety precautions.
blurred vision,  Monitor diabetic patient
weight loss). closely; drug may mask
hypoglycemia or worsen
 weakness, dizziness;
hyperglycemia.
diarrhea; dry eyes;
 WARNING: Monitor
tired feeling; or
patient for any sign of
weight gain.
hepatic impairment
(pruritus, dark urine or
stools, anorexia, jaundice,
pain); arrange for LFTs and
discontinue drug if tests
indicate liver injury. Do not
restart carvedilol.
 Take drug with meals.
 Do not stop taking drug
unless instructed to do so by
a health care provider.
 Avoid use of over-the-
counter medications.
 Advise the diabetic patient
to promptly report changes
in glucose.
 You may experience these
side effects: Depression,
dizziness, light-headedness
(avoid driving or performing
dangerous activities; getting
up and changing positions
slowly may help ease
dizziness).
 Report difficulty breathing,
swelling of extremities,
changes in color of stool or
urine, very slow heart rate,
continued dizziness.
 DRUG DRUG INDICATIONS/CONTRAINDICAT DOSAGES AND ADVERSE REACTIONS NURSING RESPONSIBILITIES
NAME CLASSIFICATI IONS ADMINISTARTI
ON ON
GENERIC antibiotic It is used for: 4.5 gm IV Q8 CNS: Headache, insomnia,  Obtain history of
NAME:  Treatment of moderate to ANST (-) fever. hypersensitivity to
piperazillin severe appendicitis, penicillins, cephalosporins,
+ uncomplicated and GI: Diarrhea, constipation, or other drugs prior to
tazobactam complicated skin and skin nausea, vomiting, dyspepsia, administration.
structure infections, endo pseudomembranous colitis.  Lab tests: C&S prior to first
BRAND metritis, pelvic inflammatory dose of the drug; start drug
NAME: disease, or nosocomial or SKIN: Rash, pruritus, pending results. Monitor
Zosyn community- hypersensitivity reactions. hematologic status with
acquired pneumonia caused prolonged therapy (Hct and
by piperacillin-resistant, Hgb, CBC with differential
piperacillin/tazobactam- and platelet count).
susceptible, beta-lactamase-  Monitor patient carefully
producing bacteria during the first 30 min after
initiation of the infusion for
Contraindications: signs of hypersensitivity.
 Hypersensitivity to  Report rash, itching, or other
piperacillin, tazobactam, signs of hypersensitivity
penicillins, cephalosporins, or immediately.
beta-lactamase inhibitors such  Report loose stools or
as clavulanic acid and diarrhea as these may
sulbactam. indicate pseudomembranous
 Kidney failure; pregnancy colitis.
(category B), lactation. Safety  Do not breast feed while
and efficacy in children <12 y taking this drug without
are not established. consulting physician.
 DRUG DRUG INDICATIONS/CONTRAINDICAT DOSAGES AND ADVERSE REACTIONS NURSING RESPONSIBILITIES
NAME CLASSIFICATI IONS ADMINISTARTI
ON ON
GENERIC Antibiotic Uses: 500 mg tab, 1 tab  Mild to moderate  Culture site of infection
NAME: OD 3x doses nausea, vomiting, before therapy.
azithromyci  Treatment of lower respiratory abdominal pain,  Administer on an empty
n infections: Acute bacterial dyspepsia, stomach 1 hour before or 2–
exacerbations of COPD due to flatulence, diarrhoea, 3 hour after meals. Food
BRAND Haemophilus influenzae, Moraxella cramping; affects the absorption of this
NAME: catarrhalis, Streptococcus  angioedema, drug.
Zithromax, pneumoniae; community-acquired cholestatic jaundice;  Prepare Zmax by adding 60
Zmax pneumonia due to S. pneumoniae, H.  dizziness, headache, mL water to bottle, shake
influenzae vertigo, somnolence; well.
 Treatment of lower respiratory  transient elevations  Counsel patients being
infections: Streptococcal pharyngitis of liver enzyme treated for STDs about
and tonsillitis due to Streptococcus values. appropriate precautions and
pyogenes in those who cannot take additional therapy.
penicillins  Take the full course
 Treatment of acute sinusitis prescribed. Do not take with
 Treatment of otitis media caused by antacids. Tablets and oral
H. influenzae, M. catarrhalis, S. suspension can be taken
pneumoniae in children > 6 mo with or without food.
 Treatment of pharyngitis and  Prepare Zmax by adding 60
tonsillitis in children > 2 yr who milliliters (1/4 cup) water to
cannot use first-line therapy bottle, shake well, drink all
 Prevention and treatment of at once.
disseminated Mycobacterium avium  You may experience these
complex (MAC) in patients with side effects: Stomach
advanced AIDS cramping, discomfort,
 Treatment of patients with mild to diarrhea; fatigue, headache
moderate acute bacterial sinusitis (medication may help);
caused by H. influenzae, Moracellis additional infections in the
catarrhalis, S. pneumoniae (Zmax) mouth or vagina (consult
 Treatment of mild to moderate with health care provider for
community acquired pneumonia treatment).
caused by Chlamydophila  Report severe or watery
pneumoniae, H. influenzae, diarrhea, severe nausea or
 Mycoplasma pneumoniae, S. vomiting, rash or itching,
pneumoniae (Zmax) mouth sores, vaginal sores.

Contraindication:

 Contraindicated with
hypersensitivity to azithromycin,
erythromycin, or any macrolide
antibiotic.
 Use cautiously with gonorrhea or
syphilis, pseudomembranous
colitis, hepatic or renal impairment,
lactation.
 DRUG DRUG INDICATIONS/CONTRAINDICAT DOSAGES AND ADVERSE REACTIONS NURSING RESPONSIBILITIES
NAME CLASSIFICATI IONS ADMINISTARTI
ON ON
GENERIC Bronchodilators It is used for: salbutamol + SIGNIFICANT: Hypersensit  Check and verify with
NAME:  COPD treatment ipatropium ivity reactions (e.g. urticaria, doctor’s order and
salbutamol Contraindications: bromide neb Q8 angioedema, rash, Kardex.
+  Hypersensitivity to anaphylaxis, bronchospasm,  Observe rights
ipatropium salbutamol, ipratropium or oropharyngeal oedema), in medication administr
bromide fenoterol, atropine or its paradoxical bronchospasm, ation such as giving the
derivatives. ocular complications (e.g. right drug to the right
BRAND  Hypertrophic obstructive mydriasis, blurred vision, patient using the right
NAME: cardiomyopathy, narrow-angle glaucoma, eye route and at the right
Combair tachyarrhythmia. pain), serious hypokalaemia, time.
 Patient with CV disorders gastrointestinal motility  Monitor ECG, serum
(e.g. ischaemic heart disturbances, rapidly electrolytes and thyroid
disease, arrhythmia, severe worsening dyspnoea, ECG function test results.
heart failure), severe airway
changes, lactic acidosis,  Administer accurately
urinary retention. Rarely, because adverse
obstruction, cystic fibrosis, myocardial ischaemia. reactions and tolerance
prostatic hyperplasia or
might occur.
bladder-neck obstruction, CARDIAC  Raise side rails up
convulsive disorders, DISORDERS: Palpitations, because client might be
hyperthyroidism, diabetes tachycardia. restless and drowsy
mellitus. Pregnancy and because of this drug.
lactation. EYE  Keep room well-lit and
DISORDERS: Accommodat see to it that client has a
ion disorders. person with him closely
in case of vertigo.
GASTROINTESTINAL  Assess lung sounds, PR
DISORDERS: Dry mouth,
and BP before drug
nausea.
administration and
NERVOUS SYSTEM during peak of
DISORDERS: Headache.
medication.
 Assess pulse for rhythm.
RESPIRATORY,
 Provide oral care or let
THORACIC AND
patient gurgle after
MEDIASTINAL
inhalation to get rid of
DISORDERS: Coughing,
dysphonia.
 the unpleasant aftertaste
of the inhalation.
 Auscultate lungs for
presence of adventitious
breath sounds that may
signal pulmonary
edema, airway
resistance or
bronchospasm.
 Inspect client’s nail bed
and oral mucosa for
pallor.
 Place client in position
of comfort to facilitate
optimum rest and sleep.
 DRUG DRUG INDICATIONS/CONTRAINDICAT DOSAGES AND ADVERSE REACTIONS NURSING RESPONSIBILITIES
NAME CLASSIFICATI IONS ADMINISTARTI
ON ON
GENERIC Mucolytic Uses: 600 mg tab OD HS  Nausea, vomiting, &  Instruct patient to follow
NAME:  Treatment of respiratory other GI symptoms, directions exactly
n- affections characterized by  generalized urticaria  Explain the importance of
acetylcestei thick & viscous accompanied by
using drug as directed
ne hypersecretions; acute mild fever,
&chronic bronchitis & its  hypotension,
BRAND wheezing, dyspnea,
NAME: exacerbation, pulmonary
and stomatitis.
Solmucol emphysema,
mucoviscidosis &
bronchiectasis. Antidote in
poisoning caused by
paracetamol, carbon
tetrachloride, arsenic,
metallic mercury
inhalation, yellow
phosphorus & for
cyclophosphamide induced
hemorrhagic cystitis
Contraindications:

 Hypersensitivity.
Phenylketonuria (contain
aspartate)
 DRUG DRUG INDICATIONS/CONTRAINDICAT DOSAGES AND ADVERSE REACTIONS NURSING RESPONSIBILITIES
NAME CLASSIFICATI IONS ADMINISTARTI
ON ON
GENERIC Proton-pump It is used for: 40 mg tab, 1 tab CNS: Headache, dizziness,  Lab tests: Monitor urinalysis
NAME: inhibitor  Duodenal and gastric ulcer. OD pre-breakkfast fatigue. for hematuria and
omeprazole Gastroesophageal reflux proteinuria. Periodic liver
disease including severe GI: Diarrhea, abdominal pain, function tests with
BRAND erosive esophagitis (4 to 8 wk nausea, mild transient prolonged use.
NAME: treatment). increases in liver function  Report any changes in
Losec,  Long-term treatment of tests. urinary elimination such as
Prilosec pathologic hypersecretory pain or discomfort
conditions such as Zollinger- Urogenital: Hematuria, associated with urination, or
Ellison syndrome, multiple proteinuria. blood in urine.
endocrine adenomas, and  Report severe diarrhea; drug
systemic mastocytosis. Skin: Rash. may need to be
 In combination with discontinued.
clarithromycin to treat  Do not breast feed while
duodenal ulcers associated taking this drug.
with Helicobacter pylori.

Contraindications:
 Long-term use for
gastroesophageal reflux
disease, duodenal ulcers;
lactation.