1.

50 year old obese alcoholic presented with right hypochondrial pain of dragging
type with anorexia. On examination , his liver was palpable 2 cm below right
costal margin. Ultrasound abdomen showed hepatomegaly. His LFT parameters
were within normal limits.

a) What is your diagnosis?

b) What precautions would you advise the patient?

c) Etiopathogenesis of the condition.

2. A 10 year old child presented to pediatric OP with complaints of blackish
discoloration of his skin and nails. On investigation, his Homogentisic acid
levels were raised.

a) What is your diagnosis?

b) What are the other pigments that you know of?

c) What is wear and tear pigment?

3. A 60 year old female patient presented with frequent syncopal attacks, fatigue,
palpitations, SOB on exertion. On examination, murmurs were heard in aortic
area. ECHO revealed stiff valves.

a) What causes the stiff valve?

b) What are the types of pathologic calcifications and their causes?

c) What is a heterotopic bone?

4. A 35 year old male presented with generalised lymphadenopathy with evening
rise of temperature and loss of weight. His lymph node biopsy was done which
revealed :-

a) What is your diagnosis?

b) What is granulomatous inflammation?

c) What are the diseases which present with such inflammation?

d) What are the types of granulomas?

5. A 7 tear old boy had an injury over shoulder while playing, for which suturing
was done. 3 months later, he presented with mass over the suture area.

a) What is your diagnosis?

b) What is the etiology of the lesion?

c) Define types of wound healing?

6. A 70 year old male, k/c/o CAD, was brought to casuality with chest pain,
sweating and dyspnoea. He collapsed while treating and was declared dead.
Lung, heart were sent for autopsy.

a) What is your diagnosis?

b) What are heart failure cells?

c) Describe the microscopy?

7. A 65 year old k/c/o long standing COPD came to the casuality with complaints
of anorexia, pedal edema and SOB. On examination she had hepatomegaly with
liver 3 cm below the right costal margin.

a) What is your diagnosis?

b) What is the etiopathology of the lesion?

c) What is the complication?

8. 55 year old chronic alcoholic presented to emergency with jaundice, protrusion
of abdomen, hematemesis. On examination, ultrasound revealed ascites and
massive splenomegaly 4cm below left costal margin with COL. Upper GI
endoscopy revealed Esophageal varices.

a) What is your diagnosis?

b) What are the causes of splenomegaly?

9. 80 year old paralytic patient who was confined to bed for 6 months who had
unilateral pedal edema with pain in the same lower limb, was brought to
emergency with sudden onset of shortness of breath and coughing up pink,
frothy sputum. He collapsed and was declared dead. Autopsy of his lung
revealed:-

a) What is your diagnosis?

b) Etiopathology of lesion?

c) Virchow’s triad? Consequence/ fate of thrombus.

d) Types of embolism.
10. 45 year old primigravida delivered a baby with following features:-

a) What is your diagnosis?

b) Discuss the abnormalities and clinical presentation?

c) Enumerate other trisomy syndromes?

11.A young mother brought 2 year old baby to pediatric OP with complaints of
reduced night vision, respiratory infections and pain during micturition.

a) What is your diagnosis?

b) What are the various functions of vitamin A?

c) RDA and hypervitaminosis A .

12. 35 year old pregnant women, who was G6P5L5 , presented with history of
frequent fractures and generalised weakness with muscle twitches. X-ray
revealed generalised osteoporosis. On examination, Trousseau’s sign was
positive. Biochemical analysis revealed :
Sr. Ca – 7 mg/dL ; Sr. Phosphorus – 4 mg/dL

a) What is your diagnosis?

b) What is the deficiency of this vitamin in children known as?

c) Metabolism of the vitamin and clinical manifestations?

13. 25 year old female who is G2P1L1 with 8 months of amenorrhoea with A
negative blood group came to obstetric OP with complaints of lack of foetal
movements. Later, she delivered a still born baby.

a) What is your diagnosis?

b) Etiopathogenesis.

c) Types of foetal hydrops? Causes of no-immunological hydrops?

d) Precautions to be taken?
14.Young mother brought 1 year old male baby to pediatric OP with complaints of
abdominal mass on left side associated with hematuria of 1 day duration. USG
abdomen revealed mass in left kidney extending across the midline.
Nephrectomy was done and specimen submitted.

a) What is your diagnosis?

b) What are the microscopic pictures?

c) Discuss the various syndromes and genetic mutations associated with the
tumour?
15. 6 month old child was brought to the pediatric OP with complaints of
increasing size of red-blue mass over the skin. On examination, mass was
present over the lower limb , which was reddish blue, elevated and disappeared
on applying pressure.

a) What is your diagnosis?

b) Morphology and types of hemangiomas, their various presentations?

c) Familial syndromes associated with the lesion?

16. 58 year old male, k/c/o diabetes, hypertension and a chronic smoker, presented
with blackish discolouration of the foot, which was gradually extending upto the
knee joint. Doppler was done which indicated narrowing of the Popliteal artery.
17. A 22 year old male, presented to cardiology OP with complaints of progressive
increasing dyspnoea, easy fatiguability, poor exercise tolerance. On ECHO, his
ejection fraction was less than 30% with mitral regurgitation and dilation of all
chambers was seen.
18. 50 year old male patient presented with a non-healing ulcer over the lower limb
which later developed into an ulceroproliferative cauliflower like mass within a
duration of 2 months. Biopsy was taken and submitted.

a) What is your diagnosis?

b) What are the various sites of presentation?

c) What are the various genetic mutations associated with this carcinoma?
19. 45 year old male patient presented to the medical OP with complaints of
generalised lymphadenopathy, weakness, malaise and easy fatiguability. On
examination, the patient had organomegaly along with cervical, inguinal,
axillary, para-aortic and mediastinal lymphadenopathy with individual lymph
node size varying from 1- 2.5 cm.

a) What is your diagnosis?

b) Classification of the neoplasms?

c) Phenotype of the cells involved?

20. 23 year old male patient presented to medical OP with history of painless
cervical lymphadenopathy associated with night sweats and weight loss with
general malaise. On examination- mediastinal lymphadenopathy was found on
X-ray. Lymph node biopsy was done and submitted.

a) What is your diagnosis?

b) What are the morphological types of HL?

c) Prognostic factors and staging of the disease.