Dermatoses Morphology
Mucinosis
2. Reticular Erythema -Characterized as erythematous
Mucinosis plaques or reticulated patches
-Predilection sites: most common
in the midline of chest and back
3. Follicular Mucinosis Alopecia Mucinosa
-Characterized by
hypopigmented/erythematous/flesh
colored, scaly/eczematous,
follicular papules
-Predilection site: face, neck, scalp -Histology: Mucin deposits on the outer root sheaths of
4. Cutaneous Focal -Asymptomatic solitary nodule or
Mucinosis papule
-Predilection site: face, neck,
trunk, extremities
5. Myxoid Cyst -Solitary, 5-7mm, opalescent or
skin colored cyst
-Cyst contain a clear viscous
sticky fluid covered in a
compacted fibrous wall
-Predilection site: dorsal hands,
lateral terminal digits of hands and
toes
Etiology Pathogenesis Treatment/Management
-F>M; 30-40 years of age
-Gradual evolution
-Eruption frequently appear after intense sun exposure
(Photosensitivity is common)
-Onset of exacerbation:
 Oral contraceptives
 Menses
 Pregnancy
 UVB exposure
Types: -Hydroxychloroquin
 Primary follicular mucinosis: skin limited, -Topical corticosteroids
benign; lesions are solitary or few in number; -Dapsone
cluster on head & neck; younger than 40 yo -PUVA
 Associated with follicular mycosis fungoides: -Minocycline
older patient -Isotretinoin
the hair follicles
-Primary follicular mucinosis: spontaneous involution
(esp in children)
-Follicular MF + Mucin: refractory to treatment; worse
prognosis than classic CTCL
-Adulthood - Surgical excision
-Clinical appearance may be indistinctive with:
 Cyst
 Basal cell carcinoma
 Neurofibroma
-Synovial mucous cyst, Digital mucous cyst -Surgical excision: cure rate
>90%
-F>M -Proximal nailfold: puncture
technique
-Osteoarthritis at the adjacent distal interphalangeal -Swelling: intralesional
joint injection of Sodium
Tetradecyl Sulfate
-If multiple: associated with CTD (JRA) -Cryotherapy, CO2 ablation,
curettage and fulguration