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Pharmacology Interventions:
• Typical Antipsychotics (1st generation): block dopamine
o positive symptoms
o dopamine (D2 receptor) antagonists (postsynaptic)
o antagonists for acetylcholine, norepinephrine, and histamine receptors
o movement-related and anticholinergic side effects
• Atypical Antipsychotics (2nd generation): block serotonin and dopamine
o positive and negative symptoms
o dopamine (postsynaptic) and serotonin (presynaptic) antagonists
o metabolic-related side effects
Complications:
• Anticholinergic toxicity
• Neuroleptic malignant syndrome (NMS)
o **know s/s
• Agranulocytosis: check blood work!!!!!
o particularly with clozapine; last line of def.
• Extrapyramidal Symptoms (EPS)
o Tardive dyskinesia:
o Dystonia:
o Pseudo-Parkinsonism:
o Akathisia: restlessness
NURSING 3125 WEEK FIVE OCT 4, 2019
Types of Therapies
• Individual and Group Therapies:
o Psychoeducation, Family therapy, Cognitive remediation, Milieu therapy, Social skills
training
• Integrative Therapies:
o Yoga, Nutrition therapy
Nursing interventions:
Establish open, trusting relationship
Assist with management of symptoms
o Do not challenge; provide reality
Provide reassurance of safety
Identify safety risk to self or others
Assist to identify new adaptive coping strategies
Promote physical health, well-being, relaxation response
Case study:
Legal implications: assault and battery; right to refuse medication unless control purposes; documentation
room visible to nursing station, take someone with you for care
NURSING 3125 WEEK FIVE OCT 4, 2019
Nursing interventions: ensure safety; trust establishment; rapport; present reality-validate their fear still;
reassure their safety.