ANALYTICAL CHEMISTRY
Kuss, H.-J. / Kromidas, S. (eds.)
September 2009. 376 pages. Hardcover.
€ 89.-
ISBN: 978-3-527-32301-2
S. Kromidas, Consultant, Saarbrücken,
Germany
H.-J. Kuss, Ludwig Maximilian
University, Munich, Germany
Quantification in LC and GC
A Practical Guide to Good Chromatographic Data
Correct chromatographic data, and
a reliable assessment of the
results, are the basic requirements
in all analytical contract work.
Practitioners as well as laboratory
leaders are routinely faced with a
number of questions:
► How do I integrate correctly, and
how do the integration parameters
and software settings influence the
final result?
► What are the special
requirements for this
chromatographic method?
and, last but not least:
► What are the requirements and
standards imposed by national and
international regulatory authorities
such as the EMEA and FDA?
The answers to all of those
questions can be found in this
practical guide. Experts from all
areas of chromatography share
practical advice on general aspects
such as integration parameters and
measurement errors, as well as on
specific challenges posed by the
various chromatographic tech-
niques: HPLC, GC, IC, GPC and
LC-MS. The views of international
regulatory authorities and industry
standards with regard to the
contents and requirements of
analytical data are discussed in
detail.
The authors have managed to
focus on the essential practical
knowledge that is most useful for
day-to-day operation.
By way of its clear structure and its
concise, self-contained chapters,
the information is easy to retrieve
and to work with.
FROM THE CONTENTS

EVALUATION AND ESTIMATION CHARACTERIZATION OF THE ORGANISATIONS AND PUBLIC

OF CHROMATOGRAPHIC DATA EVALUATION OF DIFFERENT AUTHORITIES
CHROMATOGRAPHIC MODES
Evaluating Chromatograms (Hans- The Science Behind the
Joachim Kuss and Daniel Stauffer) Evaluation and Estimation of Pharmaceutical Regulatory
Chromatographic Data in GC Chromatographic Procedures
Integration Parameters (Daniel
(Werner Engewald) (Linda Ng)
Stauffer and Hans-Joachim Kuss)
Data evaluation in LC-MS Interpretation of Chromatographic
Integration Errors
(Hartmut Kirchherr) Data According to the Pharmaco-
(Hans-Joachim Kuss)
poeias–Control of Impurities
Evaluation of Chromatography
Simulation of Chromatograms (Ulrich Rose)
Data in Ion Chromatography
(Uwe Neue)
(Heiko Herrmann and Detlef Requirements of (Chromato-
Integration of Asymmetric Peaks Jensen) graphic) Data in Pharmaceutical
(Hans-Joachim Kuss) Analysis
Qualification of GPC/GFC/SEC
(Joachim Ermer)
Deconvolution (Mike Hillebrand) Data and Results
(Daniela Held and Peter Kilz) Evaluation and Valuation of
General Interpretation of Analytical Chromatographic Data
Data (Joachim Ermer) REQUIREMENTS FOR (Stavros Kromidas)
Metrological Aspects of Chromato- CHROMATOGRAPHIC DATA
graphic Data Evaluation ANALYSIS FROM THE
(Ulrich Panne) VIEWPOINT OF

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ISBN: 978-3-527-32301-2
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