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Advances in

Histopathology of CIN
dr. Hartono Tjahjadi, SpPA (K)
Department of Anatomical Pathology, Breast and Gynecopathology Division
Universitas Indonesia, Cipto Mangunkusumo National Referral Hospital
Jakarta, Indonesia
OUTLINE
• General aspect of CIN
• Pitfalls and difficulties
• The role of galectin-3 in determining degree of CIN and
the presence of invasion
Alzamil L, Nikolakopoulou K, Turco, MY, Organoid systems to study the human female reproductive tract and pregnancy. Cell Death Differ 28, 35–51 (2021).
Margin of resection??
PITFALLS and
DIFFICULTIES
HSIL involving endocervical glands mimicking invasion

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