NUEVAESPANA, JAYNE ANGELIE A.
BSN 2A
DRUG STUDY
Name of Dosage Classification Mechanisms of Action
the Drug Frequency
Preparation
Ferrous 100mg/mg Bloods formers, Taking iron in supplement
Sulfate 2ml OD PO coagulators, and form, such as ferrous
anticoagulants sulfate, allows for more
rapid increases in iron
levels when dietary supply
and stores are not
sufficient. Iron is
transported by the divalent
metal transporter 1
(DMT1) across the
endolysosomal membrane
to enter the macrophage. It
can then can be
incorporated into ferritin
and be stored in the
macrophage or carried of
the macrophage by
ferroportin. This exported
iron is oxidized by the
enzyme to ceruloplasmin
to Fe3+, followed by
sequestration by
transferrin for transport in
the serum to various sites,
including the bone marrow
for hemoglobin synthesis
or into the liver. Iron
combines with porphyrin
and globin chains to form
hemoglobin, which is
critical for oxygen
delivery from the lungs to
Adverse Reaction
GI: Nausea,
heartburn, anorexia, constipa
tion, diarrhea, epigastric pain,
abdominal distress, black
stools.  preparations are best
Special Senses: Yellow-
brown discoloration of eyes
and teeth (liquid forms.) 
Large Chronic Doses in
Infants Rickets (due to
interference with phosphorus
absorption).  administering.
Massive
Overdosage Lethargy,
drowsiness, nausea, vomiting,
abdominal pain, diarrhea,
local corrosion of stomach
and small intestines, pallor or
cyanosis, metabolic
acidosis, shock,
cardiovascular collapse,
convulsions, liver necrosis,
coma, renal failure, death.
Nursing Considerations
 Give on an empty
stomach if possible
-An oral iron
absorbed with empty
stomach.
 Do not crush tablet or
empty contents of
capsule when
-Capsule is made to
be administered as a
whole.
 Do not give tablets or
capsules within 1 h of
bedtime.
-Capsule may have a
side effect of not
letting you sleep
quickly.
 Do not use discolored
tablets.
-It may be expired
and could affect the
NUEVAESPANA, JAYNE ANGELIE A. BSN 2A
other tissues.
Enervon C 100mg/ml Vitamin Ascorbic acid is reversibly
2.5ml OD oxidized to
dehydroascorbic acid in
the body. These two forms
of the vitamin are believed
to be important in
oxidation-reduction
reactions. The vitamin is
involved in tyrosine
metabolism, conversion of
folic acid to folinic acid,
carbohydrate metabolism,
synthesis of lipids and
proteins, iron metabolism,
resistance to infections,
and cellular respiration.
GI: Nausea, vomiting,
heartburn, diarrhea, or
abdominal cramps (high
doses).  -Patient may not want
Hematologic: Acute
hemolytic anemia (patients
with deficiency of G6PD);
sickle cell crisis.  
CNS: Headache or insomnia
(high doses).  water immediately
Urogenital: Urethritis,
dysuria, crystalluria,
hyperoxaluria, or
hyperuricemia (high doses). 
Other: Mild soreness at
injection site; dizziness and
temporary faintness with
rapid IV administration.
health of the patient.
 Store in tightly closed
containers and protect
from moisture. Store
at 15°–30° C.
-A moist content can
lead to loss of
substance.
 Give oral solutions
mixed with food.
the taste of the
medicine.
Dissolve effervescent
tablet in a glass of
before ingestion.
-In order for citric
acid and sodium
bicarbonate to react
together.
 For IM and SubQ,
open ampules with
caution.
-To prevent from
wasting the content.
NUEVAESPANA, JAYNE ANGELIE A. BSN 2A

 Be aware that
ascorbic acid
injection may
gradually darken on
exposure to light;
slight coloration
reportedly does not
affect its therapeutic
action.

-For awareness when

administering.

 For IV, verify correct

IV concentration and
rate of infusion for
children with
physician.

-To avoid overdosing

of the patient.
Mosegor 5mg/ml 2mg Vitamin It is proposed that Increased appetite  Avoid activities
Vita OD Pizotifen works by Weight gain which require
inhibiting the peripheral Drowsiness concentration.
actions of serotonin and Fatigue -The patient may
histamine in increasing the Nausea experience dizziness.
membrane permeability of Unusual weakness
cranial vessels and Rarely Dizziness  Administer with
transudation of Headache meals.
plasmakinin, while Dry mouth -To avoid G.I
altering pain thresholds in irritations.
migraines. By blocking 5-
HT receptors, pizotifen  A therapeutic
attenuates the signalling of response may require
serotonin in causing several weeks of
NUEVAESPANA, JAYNE ANGELIE A. BSN 2A
cranial vasoconstriction, as
well as serotonin-
enhanced platelet function
and aggregation. There is
evidence that it also
inhibits the peripheral
actions of bradykinin.
Pizotifen may inhibit
serotonin reuptake by
blood platelets, which
affects the tonicity and
decreases passive
distension of extracranial
arteries. The effects of
pizotifen leading to
appetite stimulation may
be due to the drug acting
at the metabolic level
rather than a direct
stimulation of the appetite
center.
Prednisone 1.25mg/ml Corticosteroids Prednisone is first
1ml BID metabolized in the liver to
its active form,
prednisolone, a
glucocorticoid agonist
corticosteroid. The short
term effects of
corticosteroids are
decreased vasodilation and
permeability of capillaries,
as well as decreased
leukocyte migration to
sites of
inflammation. Corticostero
ids binding to the
therapy.
-To see improvements
of the patient.
 Do not discontinue
abruptly.
-Discontinuing may
affect the patient’s
health and may
experience some
adverse reactions.
 Assure vitamin intake
is enough for the
child’s age.
-A child may not take
the effect of vitamins
taken by the adults.
CNS: Euphoria, headache,  Check and record BP
insomnia, confusion, during dose
psychosis.  stabilization period at
CV: CHF, edema.  least 2 times daily.
GI: Nausea, vomiting, peptic Report an ascending
ulcer.  pattern.
Musculoskeletal: Muscle
weakness, delayed wound -To determine any
healing, muscle wasting, abnormalities.
osteoporosis, aseptic necrosis
of bone, spontaneous  Be alert to signs of
fractures.  hypocalcemia.
Endocrine: Cushingoid
features, growth suppression
-To prevent
in children, carbohydrate
complications from
NUEVAESPANA, JAYNE ANGELIE A. BSN 2A

glucocorticoid receptor intolerance, hyperglycemia. 

mediates changes in gene
expression that lead to
multiple downstream
effects over hours to days.
Special Senses: Cataracts.  happening to the
Hematologic: Leukocytosis  patient.
Metabolic: Hypokalemia.
 Be aware that long-
term corticosteroid
therapy is ordinarily
not interrupted when
patient undergoes
major surgery, but
dosage may be
increased.

-The drug may affect

the child’s health if
interrupted.

 Monitor for
withdrawal syndrome.

-Patient’s condition
may be worsening.

 Be alert to possibility
of masked infection
and delayed healing.

-To add further care

and management.
Ferrous 10 mg Blood formers, The complex is GI irritation  If stomach upset
Gluconate elemental Fe coagulators and endocytosed by Nausea occurs, patient may
PO qDay anticoagulants; iron macrophages of the Stomach cramping take this medication
preparation reticuloendothelial system. Staining of teeth with food. 
Within an endosome of the Heartburn -To avoid further
macrophage, lysosome Vomiting stomach irritations.
NUEVAESPANA, JAYNE ANGELIE A. BSN 2A

fuses with the endosome Constipation

creating an acidic Diarrhea  Monitor closely for
environment leading to the Discoloration of urine S&S of severe
cleavage of the complex Dark color stools hypersensitivity
from iron. Iron is then during IV
incorporated in ferritin, administration.
transferrin or hemoglobin.
Sodium ferric gluconate -To prevent any skin
also normalizes RBC irritations.
production by binding
with hemoglobin
 Stop infusion
immediately and
notify physician if
hypersensitivity is
suspected.

-To change the route

of administration of
the drug.

 Report to physician
immediately:
Difficulty breathing,
itching, flushing,
rash, weakness, light-
headedness, pain, or
any other discomfort
during infusion.

-To discontinue drug

administration.

 Monitor vital signs

periodically during IV
administration.
NUEVAESPANA, JAYNE ANGELIE A. BSN 2A

-To know if there are

any abnormalities
occurring.