Professional Documents
Culture Documents
Administrator Manual
CE Declaration
This product is provided with a CE marking in accordance with the
regulations stated in Council Directive 93/42/EEC of June 14, 1993
0123 concerning Medical Devices. Siemens is certified by notified body 0123 to
Annex 11.3. Full Quality System.
Authorized EC Representative:
Siemens Aktiengesellschaft
Medical Solutions
Henkestraße 127 Document No. 07702850
D-91052 Erlangen Rev. 1
Germany Language: English
ii ACUSON Aspen Ultrasound System 0503
COPYRIGHT Copyright © 2003 by Siemens. All rights reserved.
No part of this publication may be reproduced, transmitted, transcribed, stored in
retrieval systems, or translated into any language or computer language, in any
form or by any means, electronic, mechanical, magnetic, optical, chemical,
manual, or otherwise, without the prior written permission of Siemens.
Siemens reserves the right to change its products and services at any time. In
addition, this manual is subject to change without notice. Siemens welcomes
customer input on corrections and suggestions for improvements to this manual.
Although Siemens has attempted to ensure accuracy throughout this manual,
Siemens assumes no liability for any errors or omissions, nor for any damages
resulting from the application or use of this information.
TRADEMARKS ACUSON, MultiHertz, Native, RES, Sequoia, SpaceTime, The Value of Vision,
Vector, ACUSON XP, ACUSON 128XP, ACUSON 128XP/4, ACUSON 128XP/10,
and AEGIS are registered trademarks of Siemens. 128XP/10c, ACUSON AcuNav,
ACUSON Aspen, ACUSON Aspen Advanced, Cadence, CCD, Convergent,
CWS3000, ACUSON Cypress, DBPro, DELTA, DIMAQ, DS3000, DTI, EF,
eUltrasound, FreeStyle, Imagegate, microCase, MICROSON, Multizone,
NewView, Perspective, PerformancePlus, ProtoCALL, OBPro, QuantX, Quik-Clip,
Solo, Signature, SST, SwiftLink, TEQ, ≅TEQ, WorkPro, WebPro, WS3000, ViewPro,
ViewPro-Net, and Xpress are trademarks of Siemens. Remote First is a service
mark of Siemens QuantX, Quik-Clip, Solo, SST and WebPro are trademarks of
Siemens.
Cidex, Cidex Plus, and Cidex 7 are registered trademarks of Surgikos, Inc. K-Y
Lubricating Gel is a trademark of Johnson & Johnson Products, Inc. IBM is a
registered trademark of International Business Machines Corporation. Metricide
is a trademark of Metrex Research Corporation. Omnicide is a trademark of
Cottrell, Ltd. Panasonic is a trademark of Matsushita Electric Industrial Co. Ltd.
Polaroid is a registered trademark of Polaroid Corporation. 3M is a registered
trademark of Minnesota Mining and Manufacturing. Apple, AppleTalk,
EtherTalk, LocalTalk, Macintosh, MultiFinder, and LaserWriter are trademarks of
Apple Computer, Inc. DOT is a registered trademark of Digital Optical
Technologies. Pinnacle Micro Inc., Kodak, and Ektascan are registered trademarks
of Eastman Kodak Company. PostScript is a registered trademark of Adobe
Systems, Incorporated. Ricoh is a trademark of Ricoh Company, Ltd. Sony is a
registered trademark of Sony Corporation of America. Verbatim is a registered
trademark of Verbatim Corporation. Tosoh is a trademark of Tosoh Corporation.
Multi-Imager is a trademark of International Imaging Electronics.
All other product names are trademarks of their respective companies.
CAUTION! In the United States of America, federal law restricts this device to sale or use by, or
on the order of, a physician.
Preface. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . vii
About Your Siemens System Manuals . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . vii
Administrator Manual Organization . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . viii
Chapter 3 Presets. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 37
Overview . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 38
Siemens Exam Presets . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 38
Using Presets . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 39
Customizing Presets . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 39
Index . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 193
About Your Siemens There are four manuals in the ACUSON Aspen system manual set:
System Manuals • This Administrator Manual contains information you use to customize
your system. In addition, it also provides reference information such
as standard Preset charts, obstetrical calculation charts, vascular and
cardiac calculation formulas and references, and an ALARA
supplement.
• Your User Manual contains information that you use regularly as you
perform ultrasound exams. It introduces you to the basic functions of
the system and identifies each operating mode and exam function.
• Your Transducer Manual contains information on available
transducers, what products to use to clean and disinfect your
transducers, and power safety considerations.
• Your Safety Manual contains important safety information for all
ACUSON systems. Read the Safety Manual before you use any
ACUSON system.
The manuals address readers who are familiar with ultrasound
techniques and, therefore, do not include sonography training or clinical
procedures.
SYMBOL DESCRIPTION
CONTROL USE
TRACKBALL Use to highlight and select a system function.
[HIDE MENU] Temporarily remove a dialog box that is
obscuring the image, and change the soft key
label to [SHOW MENU].
[SHOW MENU] Redisplay the dialog box.
[IMAGE] Return to imaging mode.
[()SELECT] Select the highlighted item.
[MODIFY] Displays a menu where you can change the
configuration for the selected setting.
[DELETE] Deletes the selected item.
[ON/OFF] Turns the selected setting on or off (toggle).
[PRIOR] or [RETURN] Return to the prior menu, either a dialog box or
the SETUP menu.
[EXIT] or SETUP Leave the SETUP function.
Command Buttons
Click to display
additional options.
Option Buttons
Click to turn on or off.
Red buttons are on.
Pop-up Menu Click to apply
Click to display the menu, changes and leave
select an option, and click the function.
again to choose the option.
• Select the method of controlling the DGC curve, either using all eight
sliders (8 POT) or using three sliders (3 POT).
• Turn on INVERT DGC to invert the DGC controls when the 2-D image
and DGC curve are inverted.
• Select the method for changing the size of the RES box. When you
select FIXED CENTER, the center of the RES box grows or shrinks
proportionately from the center. When you select FIXED CORNER, the
upper-left corner of the RES box remains stationary as the box grows
or shrinks.
Customizing Auto Auto Doppler configurations specify several sites at which to record
Doppler measurements. For each site, a configuration determines which
measurements are recorded from the spectral Doppler display. Table 1-1
lists the preset Auto Doppler configurations.
You can customize the Auto Doppler function by turning configurations
on or off. You can further customize each configuration by turning
measurements on or off and, in some cases, changing the name, number
of sites, and signal type.
Turning Configurations ◆ To configure Auto Doppler status:
On and Off
1. Select AUTO MEASURE: DOPPLER CONFIGURATION FUNCTION from
the Setup menu.
The Doppler Configuration Function menu lists each of the available
configurations and their current status, either On or Off.
LVOT LVOT
Signal Type High Volume Low Tri-Phasic Low LVOT Low Low High Volume
Resistance Resistance Resistance Resistance
Number of Sites 8 2 2 2 1 2 2 2
Measurements Live Frozen Live Frozen Live Frozen Live Frozen Live Frozen Live Frozen Live Frozen Live Frozen
Time Averaged OFF OFF OFF OFF OFF OFF OFF OFF OFF OFF OFF OFF OFF OFF OFF OFF
Max. Vel
Acceleration OFF OFF OFF OFF OFF OFF OFF OFF OFF OFF OFF OFF OFF OFF OFF OFF
Pulsatility Index OFF OFF OFF OFF OFF OFF OFF OFF OFF OFF OFF OFF ON ON ON ON
Resistivity Index OFF OFF OFF OFF OFF OFF OFF OFF OFF OFF OFF OFF ON ON OFF OFF
Systolic/Diastoli OFF OFF OFF OFF OFF OFF OFF OFF OFF OFF OFF OFF ON ON ON ON
c Ratio
Velocity Time OFF OFF OFF OFF OFF OFF OFF OFF ON ON OFF OFF OFF OFF OFF OFF
Integral
Ejection Time OFF OFF OFF OFF OFF OFF OFF OFF OFF OFF OFF OFF OFF OFF OFF OFF
Acceleration OFF OFF OFF OFF OFF OFF OFF OFF OFF OFF OFF OFF OFF OFF OFF OFF
Time
Mean Gradient OFF OFF OFF OFF OFF OFF OFF OFF OFF OFF OFF OFF OFF OFF OFF OFF
Peak Gradient OFF OFF OFF OFF OFF OFF OFF OFF OFF OFF OFF OFF OFF OFF OFF OFF
Cardiac Output OFF OFF OFF OFF OFF OFF OFF OFF ON ON OFF OFF OFF OFF OFF OFF
Selecting the You use the EX VIDEO key to activate the external video input source. The
External Video external video input source can be an external VCR or a Sony Color Page
Source Printer. (An external VCR is any VCR other than the integrated
SVO-9500MD.) When the external video input source is a VCR, the
system displays images from a videotape. When the external video input
source is a printer, the system displays printer menus or an image stored
in the printer's memory.
Depending on the external video input source and the current status of
the VCR, pressing EX VIDEO has the following effect:
Printer with:
The external video source has different default values depending on the
options installed on your system. When you turn on or reset the system,
the external video source is reset to its default value. In most cases, you
do not need to change the external video source from its default value.
CONTROL USE
Customizing The system supports many kinds of printing devices. You use the Print
Printing Control menu to install printing devices, specify how the system
responds when you print, and manually print to a specific device.
Chapter 7 contains information on setting up VCRs, printers, and
external video functions.
When one or more devices are installed and turned on, pressing PRINT
prints the screen information to each device.
◆ To control printing devices, select PERIPHS: PRINT CONTROL from
the Setup menu.
The Print Control soft key menu appears. Use the soft keys as
described in the following procedures.
CONTROL USE
Installing and Removing Installing a printer consists of three steps: physically installing the device,
Printing Devices informing the system that the device is installed, and turning on the
device. Your Siemens Customer Service Engineer will initialize your
system for your particular printers during system installation.
◆ To install or remove a printing device:
1. Press [PRINTER LIST] in the Print Control soft key menu to display a
catalog of supported devices as shown below.
NOTE: [ON/OFF] appears only when the selected device is already
installed.
Adjusting VCR You can adjust the system’s VCR signal output level.
Signal Output
WARNING! The adjustment of the video output level affects the video signal that
goes to the system monitor AND to all of the video outputs on the back
panel. For example, adjusting the video output level affects the dynamic
range, available gray scale levels, and B-color representation. Consult
your Siemens Customer Service Engineer before adjusting the video
output levels.
Changing Video You can change the way the system’s video configuration supports a
Settings VCR, external video source, or video printer.
Customizing Data System information is reported by displaying data fields and a Depth
Field and DGC Gain Compensation (DGC) curve. System parameters appear in the
Curve Appearance system data field on the right side of the screen. Displayed directly below
the system data field, each operating mode has its own data field
containing parameters for that mode. The DGC Curve also appears on the
right side of the screen. Figure 1-13 shows the system data field, 2-D data
field, and DGC curve.
Permanent
System Data Field
Removable 2-D
Data Field
Correcting the Date The system clock operates even when the system is turned off. Your
and Time Settings Siemens Customer Service Engineer sets the clock to the correct date and
time during installation. When you use the system, the current date and
time appear in the permanent system data field. You will need to reset the
time to adjust for daylight saving time.
Do not change the date and time when the image is frozen. Because
changes do not take effect until you unfreeze the image, you will not be
able to see changes as you make them. Furthermore, after you change the
date and time, you should turn the system off and back on so that the
changes will take effect immediately within the AEGIS system. (Refer to
your Safety Manual for instructions on turning the system on and off.)
◆ To change the date or time:
1. Select SCREEN DATA: DATE/TIME from the Setup menu.
2. To change the time, press [HOUR], [MINUTE] and [SECOND] to advance
to the correct hour and minute and to reset seconds to zero.
3. To change the date, press [DATE].
4. Press [DAY], [MONTH], and [YEAR] to advance to the correct day,
month, and year.
5. Press [TIME] to return to the Time soft key menu.
Setting up the The ACUSON Aspen system includes a built-in Output Display system
Output Display that lets you monitor acoustic output levels for the active transducer and
imaging modes during an exam. For information about using and
customizing the Output Display, see your User Manual.
Changing the Scale You can change the location and brightness of the scale markers that
Appearance indicate image depth in both 2-D and strip modes. In 2-D, the exact scale
options depend on the format of the transducer you are using. The
following table lists scale options for each transducer format:
Dotted-edge scale markings depend on the imaging mode you are using.
In 2-D imaging mode, a small dot appears every 10 mm along the edge of
the image and a larger dot appears every 50 mm. In combined mode, in
most cases, the scale consists of a small dot every 10 mm; in the special
cases described in the following table, the scale consists of a
medium-sized dot every 20 mm.
2/3 120 mm
1/2 160 mm
1/3 200 mm
If you are not sure whether dots are 10 mm or 20 mm apart, use calipers
to measure the distance.
In RES enhanced resolution imaging, the larger dots correspond to the
depth from the face of the transducer, not the top of the displayed image.
◆ To change the scale appearance:
1. Make sure you are in the mode for which you want to change the
scale appearance.
2. Select SCREEN DATA: SCALE from the Setup menu.
3. Press [NEXT SCALE] to cycle through the available scales for the
current transducer until you see the scale presentation you want on
the screen.
Carotid OB TCI
Venous LE
Customizing AEGIS You need to customize AEGIS system-wide parameters before you begin
System-Wide storing and printing images. You usually customize the settings for these
Functions parameters once. If you change a parameter setting during a study, the
new setting will take effect immediately.
To customize AEGIS system-wide parameters, choose AEGIS:
SYSTEM-WIDE FUNCTIONS from the Setup menu and then set options as
described in this section. When you finish making changes, press [EXIT]
or SETUP to leave this function.
Creating Capture Types You can customize the clip store settings for each capture type or stage
and Stages that you create. In order to use a Free Form protocol, you must create at
least one capture type. In order to use a Staged protocol, you must create
at least one stage.
◆ To create a capture type or stage:
1. In the AEGIS Program Customization page, select PROTOCOL and
choose either FREE FORM or STAGED.
2. Select Protocol Capture Types and type in a new name or press
[SHOW MENU] to select a name from a pop-up menu of existing
capture types.
3. Press [ADD] to add the new name or [MODIFY] to change the settings
for an existing name.
The Clip Store Settings menu appears.
Saving Clips Unlike static images, clips must be saved during a study in order to be
stored permanently.
WARNING! If clips are not saved, they will be deleted when you end the study.
IMPORTANT: If Save Clips on Capture is turned on, you will not have to include clips
in a Select Set in order to store them permanently. However, if Save
Clips on Capture is turned off and you do not include any clips in a
Select Set, all clips will be deleted when you end the study.
For more information on using the AEGIS system, see your User Manual.
PRESETS
Overview 38
ACUSON Exam Presets 38
Using Presets 39
Customizing Presets 39
ACUSON Exam The ACUSON Aspen system includes the following Exam Presets. An
Presets next to the Preset name identifies the ACUSON-provided Presets. You
cannot delete or modify the ACUSON Presets; however, you can create
your own additional Presets.
BREAST Breast OB OB
CUSTOMIZING OB CALCULATIONS
CONTROL USE
Changing the The heading at the top of each OB report page initially reads ACUSON
Report Heading Standard Calculation Report. You can replace it with your own text.
◆ To change the report heading or program name:
1. Select REPORT HEADER in the OB Calc Select menu and press
[MODIFY].
2. Type the new report header or program name.
Press [UNDO] to restore the original entry.
3. Press [ENTER] to save your changes and return to the OB Calc Select
menu.
• LMP PERCENTILE
2. Press [MODIFY] to display the entry screen and soft key menu for the
selection.
CONTROL USE
3. Refer to the sections that follow for descriptions of each of the entry
screens that you use to customize the equation, measurement, or
ratio.
NOTE: If you do not enter range coefficients, the standard deviation will
not appear on the worksheet, report, or growth curve.
4. Enter values for the MIN and MAX limits of validity for the
measurement.
5. Enter range labels for growth curves. For information on displaying
growth curves, see your User Manual.
The measurement name appears at the top of the Measurement Equation
Entry screen, shown in Figure 4-2.
NOTE:
• If you do not enter the data in the range column, the standard
deviation will not appear on the worksheet, report, or growth curve.
• Unit of measurements for linear and range are in mm. Some
published charts are in cm.
• Unit of age is in weeks. Some published charts are in days, or weeks
and days.
• The Options Table Entry allows the user to enter a blank table with a
table name only. This is permitted in order to allow linear
measurements such as APTD and TTD.
CONTROL USE
NOTE: If you do not enter range coefficients for the standard deviation,
the standard deviation will not appear in the worksheet or the
report.
6. Enter values for the MIN and MAX limits of validity for the
measurement.
The Equation Entry Option screen is shown in Figure 4-4.
NOTE:
• If you do not enter the data in the range column, the standard
deviation will not appear on the worksheet, report, or growth curve.
• Unit of measurements for area is mm2. Some published charts are in
cm2.
• Unit of measurements for linear and range are in mm. Some
published charts are in cm.
• Unit of age is in weeks. Some published charts are in days, or weeks
and days.
The options name appears at the top of the measurement table entry
screen shown in Figure 4-5
PREVIOUS PAGE Scrolls through the table toward the beginning of the
table until reaching the first page.
NEXT PAGE Scrolls through the table toward the end of the table
until reaching the last page.
CLEAR TABLE Clears the table data, not the table header information,
author or measurement name.
INSERT ROW Inserts a new row into the table above the selected row.
DELETE ROW Deletes the selected row from the table.
Adding Optional The Optional Ratio Entry screen is shown in Figure 4-6.
Biometric Ratio
3. Press [PRIOR MENU] to save the ratio and return to the OB Calc Select
menu.
◆ To set the values for the EFW Equation, move to each of the
fields and enter the following:
1. Enter the author’s name in the AUTHOR field and press the RETURN
hardkey.
Customizing the The OB calculation worksheet contains two comment pages on which
Comment Page you can add additional information about the OB exam. The first
Template comment page contains several headings for fetal anatomy and
biophysical profile. During an exam, you enter comments after these
headings. The second comment page is designed for free form comments.
You can customize the first comment page to change or delete any of the
headings.
◆ To customize the comment page template:
1. Select COMMENT PAGE TEMPLATE in the OB Calc Select menu and
press [MODIFY] to display the template shown in Figure 4-9.
Selecting Studies to You select the studies that you want to include in the vascular calculation
Include in the report by turning them on. Turning off a study removes it from the
Report calculation package and the report.
◆ To customize the vascular calculation report:
1. Press SETUP and then choose CALC SET-UP.
2. Press [VASCULAR SEL] to display the Vascular Calc Select menu.
NOTE: You cannot customize the vascular calculation package if you are
working in the package. Press CALC to exit the calculation package first.
CAROTID None
IC/CC ICA pk /CCA pk
ICA pk= Internal carotid peak systolic velocity
CCA pk= Common carotid peak systolic velocity
PI | (MAX–MIN) | / |TAMX |
MAX= Maximum velocity
MIN= Minimum velocity
TAMX= Time averaged maximum velocity
RI | (MAX –MIN) | / | MAX |
MAX= Maximum velocity
MIN= Minimum velocity
S/D RATIO |MAX/MIN |
MAX= Maximum velocity
MIN= Minimum velocity
VELOCITY None
RATIO |NUM / DEN |
NUM= Any velocity
DEN= Any velocity
% STEN A (A–a) / A x 100
A= Greater of AREA 1 and AREA 2
a= Lesser of AREA 1 and AREA 2
% STEN D (D–d) / D x 100
D= Greater of DIAM 1 and DIAM 2
d= Lesser of DIAM 1 and DIAM 2
Using the Cardiac You use the Cardiac Calc Select menu to customize the cardiac calculation
Calc Select Menu package.
◆ To customize the cardiac calculation package:
1. Press SETUP and then choose CALC SETUP.
2. Press [CARDIAC SEL] to display the first page of the Cardiac Calc
Select menu. The menu is comprised of several pages: Set-up,
2-D (three pages), M-mode, and Doppler.
NOTE: You cannot customize the cardiac calculation package if you are
working in the package. Press CALC to exit the calculation package first.
Figure 6-1 shows all six pages of the menu. For more information about
general setup, see “Customizing Cardiac Setup” on page 62. For
information about customizing calculations, see “Selecting
Measurements and Calculations” on page 63.
3. Press [PAGE] until you see the page where you want to make changes.
4. Select each item you want to change and press [ON/OFF] to turn it on
or off.
5. To leave this function, press [EXIT].
Page 3 Page 4
Page 5 Page 6
IMPORTANT: When you turn off a measurement, any calculations that use that
measurement automatically turn off. Furthermore, when you turn the
measurement back on, the calculations that use it DO NOT
automatically turn back on; to use the calculations again, you must turn
them back on. When you turn on a calculation, the measurements it
uses automatically turn on because they are required for the calculation.
Table 6-1, Table 6-2, and Table 6-3 list, by mode, the measurements and
calculations that affect each other when one or the other is turned on or
off.
a. The system can use either or both the LVOT VTI with the AoV VTI or the LVOT Vmax with the AoV Vmax.
The report indicates which values were used to calculate the AV AREA.
b. If you enter a TR Vmax, the right ventricular systolic pressure is 10 mm Hg + 4Vmax2 and is calculated
automatically. If the TR Vmax is not entered, the RA pressure heading is not displayed. You can display the
heading and manually enter it in the worksheet using [EDIT].
Setting Up the VCR The ACUSON Aspen system displays a VCR counter in the data field to
Counter identify VCR recorded time. This feature helps you keep track of where
you are in a tape. You can set the VCR counter to zero to record on a new
tape, or set it to match the number displayed on the VCR’s tape counter
when you are recording on a tape that already contains images. The tape
counter is highlighted when you are recording. The three tape counter
fields are hours, minutes, and seconds. For example:
0:45:32
Adjusting Brightness, You can adjust the brightness, color levels, and contrast during video
Color Levels, and playback.
Contrast
◆ To adjust brightness, color level, and contrast during video
playback, press VCR CTRL.
1. Press [BRIGHTEN=XX], [CONTRAST=XX], or [COLOR=XX] to select the
adjustment you want to make. Move the trackball up to increase or
down to decrease the corresponding level.
2. To save the new level as a default level, press [SAVE].
3. Repeat steps 1 and 2 for each level you want to adjust.
4. To leave this function, press RETURN or VCR CTRL.
NOTE: You cannot adjust these levels during video playback if
GAIN/FRZ/RUN is activated. The soft key menu does not appear.
WARNING! A VCR must be plugged into one of the isolated accessory outlets on the
back of the ACUSON Aspen system. Using another power source
compromises electrical patient isolation and may exceed safe leakage
current levels.
Connecting a Sony Your Siemens Customer Service Engineer installs the integrated Sony
SVO-9500MD VCR SVO-9500MD VCR for you. If you need to reinstall the VCR, refer to
Figure 7-1 for an installation diagram.
Connect to VCR 8
VCR Cable
P/N 34810
35013
Video-Out
SVHS in
Video-In
Out Left
In Left
VCR
VCR
S Video RS-232C
75¾ 75¾ S-Video
off on off on
CH-2/R CH-2/R
INDICATE
AC POWER
VCR Audio
VCR Audio
SVHS Out
Out Right
Back Panel Controls Set the controls on the back panel of the VCR as described in the
following table.
Installing and Using an An external VCR is any VCR other than the integrated Sony
External VCR SVO-9500MD. For instructions on connecting an external VCR to your
system, consult your Siemens Customer Service Engineer.
Configuring an External To set up your system to use an external VCR:
VCR
1. Change the ACUSON Aspen system external video settings to their
appropriate values for your VCR. For instructions, see “Changing the
External Video Configuration” on page 16.
2. Set the external video input source to the external VCR. For
instructions, see “Selecting the External Video Source” on page 11.
Using an External VCR You use the controls on the VCR to record and to playback videotapes.
You cannot use the VCR keys on the ACUSON Aspen system keyboard.
◆ To use an external VCR for recording or playback:
1. Press EX VIDEO to start playback on the external VCR.
2. Press EX VIDEO again to stop playback.
3. Use the controls on the VCR for all other VCR functions.
QD SYSTEM CONNECTION
ACUSON
SYSTEM
Connect to
"Quick
Disconnect"
Rear View
}
COLOR PAGE PRINTER
CONNECTIONS
CABLE EXAMPLE: SONY 5650
LABELS PRINTER
SYSTEM QUICK
DISCONNECT
CABLE P/N 39933
IMAGER IN- RED INPUT- R
1
IMAGER - REMOTE N/C
6
B/W MULTI IMAGE CAMERA
}
CABLE CONNECTIONS
LABELS EXAMPLE IIE:4000 CAMERA
Connect to Connect to
"Exp/Cntrl" "Cam Video"
Exp/Control CamVideo
Cable P/N Cable P/N
39934 39935
Video In
Remote
Expose
AC Power
Connecting a Computer You can connect any IBM PC-compatible printer, including a laser printer,
Printer that has a Centronics parallel interface. Use the printer to print text
information such as calculation reports. You must also purchase from
Siemens an IBM-compatible printer interconnect cable for use with the
ACUSON Aspen system.
WARNING! The printer must get power from the isolated accessory outlet. If it does
not, chassis leakage current may rise above a safe level and affect patient
safety. If the printer gets power from a nonisolated source, its chassis
leakage current will be coupled to the ACUSON Aspen system via the
printer interface cable.
WARNING! Verify that the total power drain from the isolated outlets by all
accessories (multi-image camera, video cassette recorder, printer, and so
on) does not exceed the limits specified in your Safety Manual. See the
particular accessory’s operator manual for specifications.
WARNING! The printer must be located at least 1.5 meters away from the patient
environment.
OB CALCULATION FORMULAS
IMPORTANT: The equations are valid only within the limits provided.
The terms gestational age and menstrual age are often used
interchangeably in ultrasound literature despite the fact that they have
different meanings. Siemens assumes that the age data in the
user-supplied table was expressed as menstrual age, regardless of how
the table is labeled.
ACUSON Aspen The standard ACUSON Aspen system programs use the following fetal
Standard Charts parameter charts:
• AC Chart, Hadlock
• BPD Chart, Hadlock
• CRL Chart, Hadlock
• FL Chart, Hadlock
• HC Chart, Hadlock
References
Calculation Valid Range Reference
Menstrual Age (MA) 12-40 weeks Hadlock, F. P., et al. 1984. Estimating Fetal Age:
Computer-Assisted Analysis of Multiple Fetal Growth
Parameters. Radiology 152:497-501.
Menstrual Age (CRL) 5.7-18 weeks Hadlock, F., et al. 1992. Fetal Crown-Rump Length:
Reevaluation of Relation to Menstrual Age (5-18 weeks) with
High-Resolution Real-Time US. Radiology 182:501-505.
Cephalic Index (CI) 14-40 weeks Hadlock, F. P., et al. 1981. The Effect of Head Shape on the
Accuracy of BPD in Estimating Fetal Gestational Age. Am. J.
Radiol. 137:83-85.
FL/AC Ratio 21-42 weeks Hadlock, F. P., et al. 1985. Use of the Femur Length/
Abdominal Circumference Ratio in Detecting the Macrosomic
Fetus. Radiology 154:503-505.
FL/BPD Ratio 23-40 weeks Hohler, C. 1981. American Journal of Obstetrics and Gynecology
141:759-762.
HC/AC Ratio 12-40 weeks Hadlock, F. P., and Athey. 1985. Ultrasound in Obstetrics and
Gynecology. C.V. Mosby Co.
EFW 12-40 weeks Hadlock F. P., et al. 1984. Sonographic Estimation of Fetal
Weight. Radiology 150:535-540. Errata noted in Radiology, Feb.,
1985.
LMP Percentile 22-40 weeks Williams, R. L., et al. 1982. Fetal Growth and Perinatal
Viability in California. Obstet. and Gynecol. 59(5):624-632.
Biophysical Profile Manning, F. A., et al. 1980. Antepartum Fetal Evaluation:
Development of a Fetal Biophysical Profile Score. Am. J.
Obstet. 136:787.
AFI Moore, T. R., et al. 1990. The Amniotic Fluid Index in Normal
Human Pregnancy. American Journal of Obstetrics and
Gynecology 162:1168-1173.
Phelan, J. P., et al. 1987. Amniotic Fluid Index Measurements
During Pregnancy. Journal of Reproductive Medicine 32:601-604.
Doppler Maulik, D., et al. 1990. Doppler Velocimetry in Obstetrics.
Obstetrics and Gynecology Clinics of North America 17:163.
Thompson, R. S., et al. 1988. Doppler Ultrasound Waveform
Indices: A/B Ratio, Pulsatility Index and Pourcelot Ratio.
British Journal of Obstetrics and Gynecology 95:581-588.
OB Charts All OB Charts are listed in alphabetical order, beginning on the next page.
86 14
103 16
130 18
151 20
174 22
198 24
220 26
242 28
254 29
264 30
276 31
286 32
298 33
308 34
320 35
326 36
338 37
346 38
354 39
360 40
Regression Equation:
MA Coeff 2SD Coeff
Q0 = 4.4901880 Q0 = 0.0000000
Q1 = 1.2778320 Q1 = 0.0000000
Q2 = – 0.0221740 Q2 = 0.0000000
Q3 = 0.0003847 Q3 = 0.0000000
Q4 = 0.0000000 Q4 = 0.0000000
Q5 = 0.0000000 Q5 = 0.0000000
4.4901880+1.2778320*AC+–0.0221740*AC^2+0.0003847*AC^3
Limits
MIN = 14.0 wks 8.6 cm
MAX = 40.0 wks 36.0 cm
Reference: Campbell, S., Wilkin, D. 1975. Ultrasonic Measurement of Fetal Abdominal Circumference
in the Evaluation of Fetal Weight. British Journal of Obstetrics and Gynecology 82. 689-697.
AC Chart, Hadlock
12-42 weeks
AC Chart, Hadlock
(continued)
Regression Equation:
MA Coeff 2SD Coeff
Q0 = 8.1400000 Q0 = 0.0000000
Q1 = 0.7530000 Q1 = 0.0000000
Q2 = 0.0036000 Q2 = 0.0000000
Q3 = 0.0000000 Q3 = 0.0000000
Q4 = 0.0000000 Q4 = 0.0000000
Q5 = 0.0000000 Q5 = 0.0000000
Limits
MIN = 12.1 wks
MAX = 42.0 wks
Reference: Hadlock, F. P. et al. 1984. Estimating Fetal Age: Computer-Assisted Analysis of Multiple
Fetal Growth Parameters. Radiology 152 (no.2) 499.
57 12
67 13
77 14
88 15
98 16
109 17
119 18
130 19
141 20
152 21
163 22
173 23
184 24
195 25
205 26
215 27
225 28
235 29
244 30
254 31
262 32
271 33
279 34
286 35
293 36
300 37
306 38
311 39
316 40
Regression Equation:
MA Coeff 2SD Coeff
Q0 = 4.4675610 Q0 = 0.0000000
Q1 = 1.4946060 Q1 = 0.0000000
Q2 = – 0.0402130 Q2 = 0.0000000
Q3 = 0.0008904 Q3 = 0.0000000
Q4 = 0.0000000 Q4 = 0.0000000
Q5 = 0.0000000 Q5 = 0.0000000
Limits
MIN = 12.0 wks
MAX = 40.0 wks
Reference: Jeanty, P., Romero, R. 1984. A Longitudinal Study of Fetal Abdominal Growth.
Obstetrical Ultrasound.
15 10 + 3 40 25 + 2
16 11 + 0 41 25 + 6
17 11 + 4
18 12 + 1 42 26 + 4
19 12 + 6 43 27 + 1
44 27 + 5
20 13 + 3 45 28 + 2
21 14 + 0 46 28 + 6
22 14 + 4 47 29 + 4
23 15 + 1 48 30 + 1
24 15 + 6 49 30 + 5
25 16 + 3
26 17 + 0 50 31+ 2
27 17 + 4 51 31 + 6
28 18 + 1 52 32 + 4
29 18 + 6 53 33 + 0
54 33 + 4
30 19 + 3 55 34 + 1
31 20 + 0 56 34 + 6
32 20 + 4 57 35 + 3
33 21 + 1 58 36 + 0
34 21 + 5 59 36 + 4
35 22 + 2
36 22 + 6 60 37 + 1
37 23 + 4 61 37 + 6
38 24 + 1 62 38 + 3
39 24 + 5 63 39 + 0
64 39 + 4
65 40 + 1
Regression Equation:
MA Coeff 2SD Coeff
Q0 = 0.3659456 Q0 = 3.3574960
Q1 = 7.5928040 Q1 = –0.0005119
Q2 = –0.9036491 Q2 = 0.0000000
Q3 = 0.2393220 Q3 = 0.0000000
Q4 = –0.0304329 Q4 = 0.0000000
Q5 = 0.0014845 Q5 = 0.0000000
Limits
MIN = 10.4 wks
MAX = 40.1 wks
Reference: Jeanty, P. and R. Romero. 1984. Obstetrical Ultrasound. McGraw Hill. Fibula Chart, Jeanty.
21.6 13
27.3 14
31.9 15
35.5 16
38.5 17
42.2 18
45.0 19
48.3 20
51.8 21
54.5 22
58.7 23
61.8 24
64.6 25
66.8 26
70.1 27
72.9 28
75.5 29
78.2 30
80.1 31
82.5 32
85.2 33
86.6 34
88.5 35
89.7 36
91.4 37
92.6 38
93.7 39
94.4 40
Regression Equation:
MA Coeff 2SD Coeff
Q0 = 9.3634460 Q0 = 0.0000000
Q1 = 2.4510590 Q1 = 0.0000000
Q2 = –0.9873671 Q2 = 0.0000000
Q3 = 0.3878420 Q3 = 0.0000000
Q4 = –0.0522160 Q4 = 0.0000000
Q5 = 0.0024480 Q5 = 0.0000000
9.3634460+2.4510590*BPD+–0.9873671*BPD^2+0.3878420*BPD^3+–
0.0522160*BPD^4+0.0024480*BPD^5
Limits
MIN = 13.0 wks 2.16 cm
MAX = 40.0 wks 9.44 cm
Reference: Campbell, S., Wilkin, D. 1975. Ultrasonic Measurement of Fetal Abdominal Circumference
in the Evaluation of Fetal Weight. British Journal of Obstetrics and Gynecology 82. 689-697.
Regression Equation:
MA Coeff 2SD Coeff
Q0 = 9.5400000 Q0 = 0.0000000
Q1 = 1.4820000 Q1 = 0.0000000
Q2 = 0.1676000 Q2 = 0.0000000
Q3 = 0.0000000 Q3 = 0.0000000
Q4 = 0.0000000 Q4 = 0.0000000
Q5 = 0.0000000 Q5 = 0.0000000
Limits
MIN = 12.1 wks
MAX = 41.6 wks
Reference: Hadlock, F.P. et al. 1984. Estimating Fetal Age: Computer-Assisted Analysis of Multiple
Fetal Growth Parameters. Radiology 152 (no.2) 499.
30 15 + 2 70 27 + 1
31 15 + 4 71 27 + 3
32 15 + 6 72 24 + 6
33 16 + 1 73 28 + 1
34 16 + 3 74 28 + 4
35 16 + 5 75 28 + 6
36 16 + 7 76 29 + 2
37 17 + 2 77 29 + 4
38 17 + 4 78 29 + 7
39 17 + 5 79 30 + 3
40 18 + 1 80 30 + 5
41 18 + 3 81 31 + 1
42 18 + 4 82 31 + 4
43 18 + 6 83 31 + 7
44 19 + 1 84 32 + 3
45 19 + 3 85 32 + 5
46 19 + 5 86 33 + 1
47 20 + 1 87 33 + 4
48 20 + 3 88 34 + 1
49 20 + 5 89 34 + 4
50 20 + 7 90 34 + 7
51 21 + 2 91 35 + 3
52 21 + 4 92 35 + 7
53 21 + 6 93 36 + 4
54 22 + 1 94 37 + 1
55 22 + 3 95 37 + 5
56 22 + 5 96 38 + 3
57 23 + 1 97 39 + 1
58 23 + 3 98 39 + 6
59 23 + 5 99 40 + 4
100 41 + 4
Regression Equation:
MA Coeff 2SD Coeff
Q0 = 3.5656910 Q0 = 0.0000000
Q1 = 6.9421940 Q1 = 0.0000000
Q2 = – 1.8968540 Q2 = 0.0000000
Q3 = 0.4028942 Q3 = 0.0000000
Q4 = –0.0403642 Q4 = 0.0000000
Q5 = 0.0015878 Q5 = 0.0000000
Limits
MIN = 12.6 wks
MAX = 41.6. wks
Reference: Hansmann, M., et al. 1985. Ultrasound Diagnosis in Obstetrics and Gynecology.
Springer-Verlag.
30 14 + 4 64 24 + 6
31 14 + 6 65 25 + 2
32 15 + 1 66 25 + 4
33 15 + 2 67 26
34 15 + 4 68 26 + 3
35 15 + 6 69 26 + 5
36 16 + 1 70 27 + 1
37 16 + 3 71 27 + 4
38 16 + 5 72 27 + 6
39 17 73 28 + 2
40 17 + 2 74 28 + 5
41 17 + 4 75 29 + 1
42 17 + 6 76 29 + 4
43 18 + 1 77 29 + 6
44 18 + 3 78 30 + 2
45 18 + 5 79 30 + 5
46 19 80 31 + 1
47 19 + 2 81 31 + 4
48 19 + 4 82 32
49 19 + 6 83 32 + 4
50 20 + 2 84 32 + 6
51 20 + 4 85 33 + 3
52 20 + 6 86 33 + 6
53 21 + 1 87 34 + 2
54 21 + 4 88 34 + 6
55 21 + 6 89 35 + 2
56 22 + 1 90 35 + 5
57 22 + 4 91 36 + 1
58 22 + 6 92 36 + 5
59 23 + 1 93 37 + 1
60 23 + 4 94 37 + 5
61 23 + 6 95 38 + 2
Regression Equation:
MA Coeff 2SD Coeff
Q0 = 5.7525730 Q0 = 0.0000000
Q1 = 3.6829320 Q1 = 0.0000000
Q2 = –0.4774910 Q2 = 0.0000000
Q3 = 0.0946081 Q3 = 0.0000000
Q4 = –0.0073637 Q4 = 0.0000000
Q5 = 0.0002514 Q5 = 0.0000000
Limits
MIN = 14.0 wks
MAX = 38.3 wks
Reference: Jeanty, P. and R. Romero. 1984. Obstetrical Ultrasound. McGraw Hill.
27 14
31 15
34 16
38 17
41 18
45 19
48 20
51 21
54 22
57 23
60 24
63 25
66 26
69 27
71 28
74 29
76 30
79 31
81 32
83 33
85 34
87 35
89 36
91 37
92 38
94 39
95 40
Regression Equation:
MA Coeff 2SD Coeff
Q0 = 5.6546870 Q0 = –7.0429760
Q1 = 4.3971500 Q1 = 0.9529071
Q2 = –0.9223110 Q2 = – 0.0337610
Q3 = 0.2162220 Q3 = 0.0003800
Q4 = –0.0222450 Q4 = 0.0000000
Q5 = 0.0009221 Q5 = 0.0000000
Limits
MIN = 14.0 wks
MAX = 40.0 wks
Reference: Kurtz, A.B., et al. 1980. Analysis of Biparietal Diameter as an Accurate Indicator of Gestation
Age. J. Clin. Ultrasound 8:319.
28 14
32 15
36 16
39 17
42 18
45 19
48 20
51 21
54 22
58 23
61 24
64 25
67 26
70 27
72 28
75 29
78 30
80 31
82 32
85 33
87 34
88 35
90 36
92 37
93 38
94 39
95 40
Regression Equation:
MA Coeff 2SD Coeff
Q0 = 4.9921070 Q0 = 0.0000000
Q1 = 5.4484330 Q1 = 0.0000000
Q2 = –1.7498230 Q2 = 0.0000000
Q3 = 0.4740796 Q3 = 0.0000000
Q4 = – 0.0556882 Q4 = 0.0000000
Q5 = 0.0024200 Q5 = 0.0000000
Limits
MIN = 14.0 wks
MAX = 40.0 wks
Reference: Sabbagha, R.E. and M. Hughey. 1978. Standardization of Sonar Cephalometry and
Gestational Age. Obstet Gynecol. 52:402.
Regression Equation:
MA Coeff 2SD Coeff
Q0 = 5.386194 Q0 = 0.0000000
Q1 = 3.383561 Q1 = 0.0000000
Q2 = –0.091307 Q2 = 0.0000000
Q3 = 0.011580 Q3 = 0.0000000
Q4 = 0.000000 Q4 = 0.0000000
Q5 = 0.000000 Q5 = 0.0000000
Limits
MIN = 11.6 wks
MAX = 39.8 wks
Reference: Hobbins, John C., M.D., et al. 1983. Ultrasonography in Obstetrics and Gynecology.
Second Edition. Williams & Wilkins, Baltimore, M.D.
Yale Nomogram for BPD using leading edge to leading edge based on B-mode dots (graticule).
22.0 21.4
23.0 22.1
24.0 23.0
25.0 23.6
28.0 26.0
29.0 26.5
30.0 27.3
31.0 28.1
34.0 30.1
35.0 30.5
38.0 32.3
38.0 32.3
40.0 33.4
40.0 33.4
40.5 —
43.0 34.6
45.0 35.4
48.5 —
52.0 36.5
a
Calculated Menstrual Age is based on Goldstein’s
Regression Equation.
Regression Equation:
MA Coeff 2SD Coeff
Q0 = 6.3290000 Q0 = 0.0000000
Q1 = 4.8070000 Q1 = 0.0000000
Q2 = 1.4840000 Q2 = 0.0000000
Q3 = -0.2474000 Q3 = 0.0000000
Q4 = 0.0000000 Q4 = 0.0000000
Q5 = 0.0000000 Q5 = 0.0000000
Limits
MIN = 15.0 wks
MAX = 36.5 wks
Reference: Goldstein, I. 1987. Cerebellum Measurements with Ultrasonography in the Evaluation of
Fetal Growth and Development. American Journal of Obstetrics and Gynecology. 1987.156:1065-1069
15.0 16
16.0 17
17.0 18
18.5 19
20.0 20
21.0 21
23.0 22
24.0 23
25.0 24
27.0 25
28.0 26
29.5 27
31.5 28
33.0 29
35.0 30
36.5 31
38.5 32
40.0 33
42.5 34
46.0 35
49.0 36
53.0 37
Regression Equation:
MA Coeff 2SD Coeff
Q0 = – 8.0795850 Q0 = 0.0000000
Q1 = 29.3032400 Q1 = 0.0000000
Q2 = –14.0328700 Q2 = 0.0000000
Q3 = 4.4554060 Q3 = 0.0000000
Q4 = –0.7016286 Q4 = 0.0000000
Q5 = 0.04166980 Q5 = 0.0000000
Limits
MIN = 16.0 wks
MAX = 37.0 wks
Reference: McLeary, R. D. 1984. Ultrasonography of the Fetal Cerebellum. Radiology. 1984:151: 439-442.
Regression Equation:
MA Coeff 2SD Coeff
Q0 = 5.340164 Q0 = .0000000
Q1 = 1.921032 Q1 = .0800000
Q2 = –.1690442 Q2 = .0000000
Q3 = .0081207 Q3 = .0000000
Q4 = .0000000 Q4 = .0000000
Q5 = .0000000 Q5 = .0000000
Limits
MIN = 5.7 wks
MAX = 18.0 wks
Reference: Hadlock, F., et al. 1992. Fetal Crown-Rump Length: Reevaluation of Relation to Menstrual
Age (5-18 weeks) with High-Resolution Real-Time US. Radiology 1992; 182:501-505.
Regression Equation:
MA Coeff 2SD Coeff
Q0 = 6.3033400 Q0 = 3.7844860
Q1 = 2.0630870 Q1 = –0.7265692
Q2 = –0.1780907 Q2 = 0.0568590
Q3 = 0.0075699 Q3 = –0.0012292
Q4 = 0.0000000 Q4 = 0.0000000
Q5 = 0.0000000 Q5 = 0.0000000
Limits
MIN = 7.1 wks
MAX = 22.4 wks
Reference: Hansmann, M., et. al. 1985. Ultrasound Diagnosis in Obstetrics and Gynecology.
Springer-Verlag.
10 7+2 35 10 + 3
11 7+3 36 10 + 4
12 7+4 37 10 + 4
13 7+6 38 10 + 5
14 7+6 39 10 + 6
15 8+1 40 10 + 6
16 8+1 41 11 + 0
17 8+3 42 11 + 1
18 8+4 43 11 + 1
19 8+4 44 11 + 1
20 8+6 45 11 + 2
21 8+6 46 11 + 3
22 9+0 47 11 + 4
23 9+1 48 11 + 4
24 9+1 49 11 + 5
25 9+3 50 11 + 6
26 9+4 51 11 + 6
27 9+4 52 11 + 6
28 9+5 53 12 + 0
29 9+6 54 12 + 1
Regression Equation:
MA Coeff 2SD Coeff
Q0 = 5.2797150 Q0 = 0.0000000
Q1 = 2.2739030 Q1 = 0.0000000
Q2 = – 0.3109710 Q2 = 0.0000000
Q3 = 0.0231365 Q3 = 0.0000000
Q4 = 0.0000000 Q4 = 0.0000000
Q5 = 0.0000000 Q5 = 0.0000000
Limits
MIN = 6.3 wks
MAX = 12.1 wks
Reference: Jeanty, P. and R. Romero. 1984. Obstetrical Ultrasound. McGraw Hill.
20 9.0
22 9.2
24 9.3
26 9.5
28 9.7
30 9.9
32 10.0
34 10.2
36 10.4
38 10.5
40 10.7
42 10.9
44 11.1
46 11.2
48 11.4
50 11.6
52 11.7
54 11.9
56 12.1
58 12.3
60 12.4
62 12.6
64 12.8
66 12.9
68 13.1
70 13.3
72 13.5
74 13.6
76 13.8
78 14.0
80 14.1
Regression Equation:
MA Coeff 2SD Coeff
Q0 = 7.2341430 Q0 = 0.0000000
Q1 = 0.8856020 Q1 = 0.0000000
Q2 = –0.0046905 Q2 = 0.0000000
Q3 = 0.0002347 Q3 = 0.0000000
Q4 = 0.0000000 Q4 = 0.0000000
Q5 = 0.0000000 Q5 = 0.0000000
Limits
MIN = 8.1 wks
MAX = 14.1 wks
Reference: Nelson, L. H. 1981. Comparison of methods for determining crown-rump measurement by
real-time ultrasound. J. Clin. Ultrasound. 9:67-70.
Regression Equation:
MA Coeff 2SD Coeff
Q0 = 4.9339120 Q0 = 0.0000000
Q1 = 2.8007000 Q1 = 0.0000000
Q2 = – 0.6356975 Q2 = 0.0000000
Q3 = 0.1170670 Q3 = 0.0000000
Q4 = – 0.0116220 Q4 = 0.0000000
Q5 = 0.0004623 Q5 = 0.0000000
Limits
MIN = 6.4 wks
MAX = 14.0 wks
Reference: Robinson, H.P. et. al. 1975. A Critical Evaluation of Sonar “Crown-Rump Length”
Measurements. British Journal of Obstetrics and Gynecology, 82. (Sept.) 707.
Regression Equation:
MA Coeff 2SD Coeff
Q0 = 4.9991370 Q0 = 0.0000000
Q1 = 3.0815570 Q1 = 0.0000000
Q2 = – 0.9486124 Q2 = 0.0000000
Q3 = 0.2253123 Q3 = 0.0000000
Q4 = – 0.0268326 Q4 = 0.0000000
Q5 = 0.0012157 Q5 = 0.0000000
Limits
MIN = 5.6 wks
MAX = 14.2 wks
Reference: Robinson, H.P. and J. E. E. Fleming. 1975. A Critical Evaluation of Sonar
“Crown-Rump Length” Measurements. British Journal of Obstetrics and Gynecology. 82: 702-710.
(modified)
Yeh Hsui Chung MD. 1988. Amniotic Sac Development, Ultrasound Feature of Early
Pregnancy. Radiology. 166:97-103.
3.1 225 235 245 256 267 279 292 304 318 332 347 362 378
3.2 231 241 252 263 275 287 299 313 327 341 356 372 388
3.3 238 248 259 270 282 295 308 321 335 350 365 381 398
3.4 245 255 267 278 290 303 316 330 344 359 375 391 408
3.5 252 263 274 286 298 311 325 339 353 369 385 401 418
3.6 259 270 282 294 307 320 334 348 363 378 395 411 429
3.7 267 278 290 302 315 329 343 357 372 388 405 422 440
3.8 275 286 298 311 324 338 352 367 382 399 415 433 451
3.9 283 295 307 320 333 347 362 377 393 409 426 444 463
4.0 291 303 316 329 342 357 372 387 403 420 437 456 475
4.1 299 312 325 338 352 367 382 397 414 431 449 467 487
4.2 308 321 334 348 362 377 392 408 425 442 460 479 499
4.3 317 330 343 357 372 387 403 419 436 454 472 492 512
4.4 326 340 353 368 382 398 414 431 448 466 485 504 525
4.5 336 349 363 378 393 409 425 442 460 478 497 517 538
4.6 346 359 374 389 404 420 437 454 472 491 510 531 552
4.7 356 370 384 400 415 432 449 466 485 504 524 544 566
4.8 366 381 395 411 427 444 461 479 498 517 537 558 580
4.9 377 392 407 422 439 456 474 492 511 531 551 573 595
5.0 388 403 418 434 451 468 486 505 525 545 566 587 610
5.1 399 414 430 447 464 481 500 519 539 559 580 603 626
5.2 411 426 443 459 477 495 513 533 553 574 596 618 641
5.3 423 439 455 472 490 508 527 547 568 589 611 634 658
5.4 435 451 468 486 504 522 542 562 583 605 627 650 675
5.5 448 464 482 499 518 537 557 577 598 620 643 667 692
5.6 461 478 495 513 532 552 572 593 614 637 660 684 709
5.7 474 492 509 528 547 567 587 609 631 654 677 702 727
5.8 488 506 524 543 562 583 604 625 648 671 695 720 746
5.9 503 520 539 558 578 599 620 642 665 689 713 739 765
6.0 517 536 554 574 594 615 637 659 683 707 732 758 784
6.1 532 551 570 590 611 632 654 677 701 725 751 777 804
6.2 548 567 587 607 628 650 672 696 720 745 770 797 825
6.3 564 583 603 624 645 668 691 714 739 764 790 818 846
6.4 580 600 621 642 664 686 709 734 759 784 811 839 867
6.5 597 617 638 660 682 705 729 753 779 805 832 860 889
6.6 615 635 657 678 701 725 749 774 800 826 854 882 912
6.7 633 654 675 698 721 745 769 795 821 848 876 905 935
6.8 651 673 695 717 741 765 790 816 843 870 899 928 959
6.9 670 692 714 738 762 786 812 838 865 893 922 952 983
7.0 690 712 735 758 783 808 834 861 888 917 946 977 1008
7.1 710 733 756 780 805 830 857 884 912 941 971 1002 1034
7.2 731 754 777 802 827 853 880 908 936 966 996 1028 1060
7.3 752 775 800 825 850 877 904 932 961 991 1022 1054 1087
7.4 774 798 822 848 874 901 929 958 987 1018 1049 1081 1115
7.5 797 821 846 872 898 926 954 983 1013 1044 1076 1109 1143
7.6 820 845 870 896 924 952 980 1010 1041 1072 1104 1138 1172
7.7 844 869 895 922 949 978 1007 1037 1068 1100 1133 1167 1202
7.8 868 894 921 948 976 1005 1035 1065 1097 1129 1163 1197 1233
7.9 894 920 947 975 1003 1033 1063 1094 1126 1159 1193 1228 1264
8.0 920 946 974 1002 1031 1061 1092 1124 1156 1190 1224 1260 1296
8.1 947 974 1002 1030 1060 1090 1122 1154 1187 1221 1256 1292 1329
8.2 974 1002 1030 1060 1090 1121 1152 1185 1219 1253 1289 1325 1363
8.3 1003 1031 1060 1090 1120 1152 1184 1217 1251 1286 1322 1360 1398
8.4 1032 1061 1090 1120 1151 1183 1216 1250 1285 1320 1357 1395 1433
8.5 1062 1091 1121 1152 1184 1216 1249 1284 1319 1355 1392 1431 1470
8.6 1093 1123 1153 1185 1217 1250 1284 1318 1354 1391 1429 1467 1507
8.7 1125 1155 1186 1218 1251 1284 1319 1354 1390 1428 1466 1505 1545
Biparietal
Diameter
15.5 16.0 16.5 17.0 17.5 18.0 18.5 19.0 19.5 20.0 20.5 21.0 21.5
8.8 1158 1189 1220 1252 1286 1320 1355 1391 1427 1465 1504 1544 1585
8.9 1192 1223 1255 1288 1322 1356 1392 1428 1466 1504 1543 1584 1625
9.0 1227 1258 1291 1324 1358 1394 1430 1467 1505 1544 1583 1624 1666
9.1 1262 1295 1328 1362 1396 1432 1469 1506 1545 1584 1625 1666 1709
9.2 1299 1332 1366 1400 1435 1472 1509 1547 1586 1626 1667 1709 1752
9.3 1337 1370 1405 1440 1476 1512 1550 1589 1628 1669 1711 1753 1797
9.4 1376 1410 1445 1480 1517 1554 1592 1632 1672 1713 1755 1798 1843
9.5 1416 1451 1486 1522 1559 1597 1636 1676 1716 1758 1801 1845 1890
9.6 1458 1493 1529 1565 1603 1641 1681 1721 1762 1805 1848 1892 1938
9.7 1500 1536 1572 1609 1648 1687 1727 1767 1809 1852 1896 1941 1987
9.8 1544 1580 1617 1655 1694 1733 1774 1815 1858 1901 1945 1991 2037
9.9 1589 1626 1663 1702 1741 1781 1822 1864 1907 1951 1996 2042 2089
10.0 1636 1673 1711 1750 1790 1830 1872 1915 1958 2003 2048 2095 2142
Biparietal
Diameter
22.0 22.5 23.0 23.5 24.0 24.5 25.0 25.5 26.0 26.5 27.0 27.5 28.0
8.8 1627 1670 1714 1760 1806 1854 1903 1954 2005 2059 2113 2169 2227
8.9 1668 1711 1756 1802 1849 1898 1947 1998 2051 2104 2160 2216 2274
9.0 1710 1754 1799 1846 1893 1942 1993 2044 2097 2151 2207 2264 2323
9.1 1753 1797 1843 1890 1939 1988 2039 2091 2145 2199 2256 2313 2372
9.2 1797 1842 1888 1936 1985 2035 2087 2139 2193 2249 2305 2364 2423
9.3 1842 1888 1935 1983 2032 2083 2135 2188 2243 2299 2356 2415 2475
9.4 1888 1935 1982 2031 2081 2132 2185 2238 2294 2350 2408 2467 2528
9.5 1935 1983 2031 2080 2131 2182 2236 2290 2346 2403 2461 2521 2582
9.6 1984 2032 2080 2130 2182 2234 2287 2342 2399 2456 2515 2575 2637
9.7 2034 2082 2131 2182 2234 2287 2341 2396 2453 2511 2570 2631 2694
9.8 2085 2134 2184 2235 2287 2340 2395 2451 2508 2567 2627 2688 2751
9.9 2137 2187 2237 2289 2342 2396 2451 2507 2565 2624 2685 2747 2810
10.0 2191 2241 2292 2344 2398 2452 2508 2565 2623 2683 2744 2806 2870
3.1 696 727 759 793 828 865 904 944 986 1030 1076 1123 1173
3.2 711 742 775 809 845 882 921 962 1004 1049 1095 1143 1194
3.3 726 757 791 825 862 899 939 980 1023 1068 1115 1163 1214
3.4 741 773 807 842 879 917 957 998 1042 1087 1135 1184 1235
3.5 757 789 823 859 896 935 975 1017 1061 1107 1155 1205 1257
3.6 773 806 840 876 914 953 994 1037 1081 1127 1176 1226 1279
3.7 789 822 857 894 932 972 1013 1056 1101 1148 1197 1248 1301
3.8 805 839 875 912 950 991 1032 1076 1122 1169 1218 1270 1323
3.9 822 857 893 930 969 1010 1052 1096 1142 1190 1240 1292 1346
4.0 840 875 911 949 989 1030 1073 1117 1164 1212 1263 1315 1370
4.1 857 893 930 968 1008 1050 1093 1138 1185 1234 1285 1338 1394
4.2 876 911 949 988 1028 1070 1114 1160 1207 1257 1308 1362 1418
4.3 894 930 968 1008 1049 1091 1136 1182 1230 1280 1332 1386 1442
4.4 913 950 988 1028 1069 1112 1157 1204 1253 1303 1356 1410 1467
4.5 932 969 1008 1049 1091 1134 1180 1227 1276 1327 1380 1435 1493
4.6 952 990 1029 1070 1112 1156 1202 1250 1300 1351 1405 1461 1519
4.7 972 1010 1050 1091 1134 1179 1225 1274 1324 1376 1430 1487 1545
4.8 992 1031 1071 1113 1157 1202 1249 1298 1348 1401 1456 1513 1572
4.9 1013 1052 1093 1136 1180 1225 1273 1322 1373 1427 1482 1539 1599
5.0 1035 1074 1116 1159 1203 1249 1297 1347 1399 1453 1509 1567 1627
5.1 1056 1097 1138 1182 1227 1274 1322 1373 1425 1479 1536 1594 1655
5.2 1079 1119 1162 1206 1251 1299 1348 1399 1452 1506 1563 1623 1684
5.3 1101 1143 1185 1230 1276 1324 1374 1425 1479 1534 1591 1651 1713
5.4 1125 1166 1210 1255 1301 1350 1400 1452 1506 1562 1620 1680 1743
5.5 1148 1191 1234 1280 1327 1376 1427 1479 1534 1591 1649 1710 1773
5.6 1172 1215 1260 1306 1354 1403 1454 1507 1563 1620 1679 1740 1804
5.7 1197 1241 1286 1332 1380 1430 1482 1536 1592 1649 1709 1771 1835
5.8 1222 1266 1312 1359 1408 1458 1511 1565 1621 1679 1740 1802 1867
5.9 1248 1293 1339 1386 1436 1487 1540 1595 1651 1710 1771 1834 1899
6.0 1274 1319 1366 1414 1464 1516 1569 1625 1682 1741 1803 1866 1932
6.1 1301 1347 1394 1443 1493 1545 1599 1655 1713 1773 1835 1899 1966
6.2 1329 1375 1422 1472 1523 1576 1630 1687 1745 1806 1868 1933 2000
6.3 1357 1403 1452 1501 1553 1606 1662 1719 1778 1839 1902 1967 2035
6.4 1385 1433 1481 1532 1584 1638 1693 1751 1811 1872 1936 2002 2070
6.5 1415 1462 1512 1563 1615 1670 1726 1784 1844 1906 1971 2037 2106
6.6 1444 1493 1542 1594 1647 1702 1759 1818 1879 1941 2006 2073 2142
6.7 1475 1524 1574 1626 1680 1736 1793 1852 1914 1977 2042 2110 2180
6.8 1506 1555 1606 1659 1713 1769 1827 1887 1949 2013 2079 2147 2217
6.9 1538 1588 1639 1692 1747 1804 1862 1923 1985 2050 2116 2185 2256
7.0 1570 1621 1673 1726 1782 1839 1898 1959 2022 2087 2154 2224 2295
7.1 1603 1654 1707 1761 1817 1875 1935 1996 2060 2125 2193 2263 2335
7.2 1637 1689 1742 1797 1853 1912 1972 2034 2098 2164 2232 2303 2375
7.3 1671 1724 1777 1833 1890 1949 2010 2072 2137 2204 2273 2343 2417
7.4 1707 1759 1814 1870 1928 1987 2048 2112 2177 2244 2313 2385 2459
7.5 1743 1796 1851 1907 1966 2026 2088 2152 2217 2285 2355 2427 2501
7.6 1779 1833 1889 1946 2005 2065 2128 2192 2259 2327 2397 2470 2545
7.7 1817 1871 1927 1985 2044 2106 2169 2234 2301 2369 2440 2513 2589
7.8 1855 1910 1967 2025 2085 2147 2210 2276 2343 2413 2484 2558 2634
7.9 1894 1950 2007 2066 2126 2189 2253 2319 2387 2457 2529 2603 2679
8.0 1934 1990 2048 2107 2169 2231 2296 2363 2431 2502 2574 2649 2726
8.1 1975 2032 2090 2150 2212 2275 2340 2407 2477 2548 2621 2696 2773
8.2 2017 2074 2133 2193 2255 2319 2385 2453 2523 2594 2668 2743 2821
8.3 2059 2117 2176 2237 2300 2365 2431 2499 2569 2642 2716 2792 2870
8.4 2103 2161 2221 2282 2346 2411 2478 2547 2617 2690 2764 2841 2920
8.5 2147 2206 2266 2328 2392 2458 2525 2595 2666 2739 2814 2891 2971
8.6 2192 2252 2313 2375 2440 2506 2574 2644 2715 2789 2865 2942 3022
8.7 2238 2298 2360 2423 2488 2555 2623 2694 2766 2840 2916 2994 3075
Biparietal
Diameter
28.5 29.0 29.5 30.0 30.5 31.0 31.5 32.0 32.5 33.0 33.5 34.0 34.5
8.8 2286 2346 2408 2472 2538 2605 2674 2745 2817 2892 2969 3047 3128
8.9 2334 2395 2457 2522 2588 2656 2725 2797 2870 2945 3022 3101 3182
9.0 2383 2445 2508 2573 2639 2707 2778 2849 2923 2999 3076 3156 3238
9.1 2433 2495 2559 2624 2692 2760 2831 2903 2977 3054 3132 3212 3294
9.2 2484 2547 2611 2677 2745 2814 2885 2958 3033 3109 3188 3268 3351
9.3 2537 2600 2665 2731 2799 2869 2941 3014 3089 3166 3245 3326 3409
9.4 2590 2654 2719 2786 2855 2925 2997 3071 3147 3224 3304 3385 3468
9.5 2645 2709 2775 2842 2912 2982 3055 3129 3205 3283 3363 3445 3528
9.6 2701 2765 2832 2900 2969 3041 3114 3188 3265 3343 3423 3505 3590
9.7 2757 2823 2890 2958 3028 3100 3173 3248 3325 3404 3485 3567 3652
9.8 2816 2881 2949 3018 3088 3160 3234 3310 3387 3466 3547 3630 3715
9.9 2875 2941 3009 3078 3149 3222 3296 3372 3450 3530 3611 3695 3780
10.0 2936 3002 3071 3141 3212 3285 3360 3436 3514 3594 3676 3760 3845
Biparietal
Diameter
35.0 35.5 36.0 36.5 37.0 37.5 38.0 38.5 39.0 39.5 40.0
8.8 3211 3296 3383 3473 3565 3659 3756 3856 3958 4063 4171
8.9 3266 3351 3439 3529 3621 3716 3813 3913 4016 4121 4229
9.0 3321 3407 3495 3586 3679 3774 3871 3972 4074 4180 4288
9.1 3378 3464 3553 3644 3737 3832 3930 4031 4134 4239 4348
9.2 3435 3522 3611 3702 3796 3892 3990 4091 4194 4300 4408
9.3 3494 3581 3670 3762 3856 3952 4050 4151 4255 4361 4470
9.4 3554 3641 3731 3823 3917 4013 4112 4213 4317 4423 4532
9.5 3614 3702 3792 3884 3979 4075 4174 4276 4380 4486 4595
9.6 3676 3764 3854 3947 4041 4138 4238 4339 4444 4550 4659
9.7 3738 3827 3918 4010 4105 4203 4302 4404 4508 4615 4724
9.8 3802 3891 3982 4075 4170 4268 4367 4470 4574 4681 4790
9.9 3867 3956 4047 4141 4236 4334 4434 4536 4641 4748 4857
10.0 3933 4022 4114 4207 4303 4401 4501 4604 4708 4815 4925
Regression Equation:
T0 = 1.2508000 X NONE X NONE
T1 = 0.1660000 X (BPD) X NONE
T2 = 0.0460000 X (AC) X NONE
T3 = –0.0026460 X (BPD) X (AC)
T4 = 0.0000000 X NONE X NONE
T5 = 0.0000000 X NONE X NONE
Reference: Shepard, M.J., et. al. 1982. An Evaluation of Two Equations for Predicting Fetal Weight by
Ultrasound. American Journal of Obstetrics and Gynecology. 147: 47-54.
6 12
9 13
12 14
15 15
18 16
21 17
23 18
26 19
28 20
31 21
33 22
35 23
37 24
40 25
42 26
44 27
45 28
47 29
49 30
51 31
52 32
54 33
55 34
57 35
58 36
59 37
61 38
62 39
63 40
Regression Equation:
MA Coeff 2SD Coeff
Q0 = 10.31506 Q0 = 0.0000000
Q1 = 2.651455 Q1 = 0.0000000
Q2 = 0.3790657 Q2 = 0.0000000
Q3 = –0.0615157 Q3 = 0.0000000
Q4 = 0.0083915 Q4 = 0.0000000
Q5 = 0.0000000 Q5 = 0.0000000
Limits
MIN = 12.0 wks
MAX = 40.0 wks
Reference: Jeanty, P. and R. Romero. 1984. Obstetrical Ultrasound. McGraw Hill.
FL Chart, Campbell
12 - 40 weeks
FL Menstrual Age
(mm) (weeks)
10.0 12
14.0 13
16.6 14
19.9 15
22.0 16
25.2 17
29.6 18
32.4 19
34.8 20
37.5 21
40.9 22
43.5 23
46.4 24
48.0 25
51.1 26
53.0 27
54.4 28
57.3 29
58.7 30
61.5 31
62.8 32
64.9 33
65.7 34
67.7 35
69.5 36
70.8 37
71.8 38
74.2 39
75.4 40
Regression Equation:
MA Coeff 2SD Coeff
Q0 = 7.920067 Q0 = 0.0000000
Q1 = 4.397133 Q1 = 0.0000000
Q2 = – 0.560659 Q2 = 0.0000000
Q3 = 0.090984 Q3 = 0.0000000
Q4 = – 0.002513 Q4 = 0.0000000
Q5 = 0.000000 Q5 = 0.0000000
7.920067+4.397133*FL+–0.560659*FL^2+0.090984*FL^3+–0.002513*FL^4
Limits
MIN = 12.0 wks 1.0 cm
MAX = 40.0 wks 7.54 cm
FL Chart, Hadlock
12.2 - 42 weeks
FL MA 2 Std FL MA 2 Std FL MA 2 Std
(mm) (weeks) Dev (mm) (weeks) Dev (mm) (weeks) Dev
Regression Equation:
MA Coeff 2SD Coeff
Q0 = 10.3500000 Q0 = 0.0000000
Q1 = 2.4600000 Q1 = 0.0000000
Q2 = 0.1700000 Q2 = 0.0000000
Q3 = 0.0000000 Q3 = 0.0000000
Q4 = 0.0000000 Q4 = 0.0000000
Q5 = 0.0000000 Q5 = 0.0000000
Limits
MIN = 12.2 wks
MAX = 42.0 wks
Reference: Hadlock, F.P. et al. 1984. Estimating Fetal age: Computer-Assisted Analysis of Multiple
Fetal Growth Parameters. Radiology 152 (no.2) 499.
FL Chart, Hansmann
17.1 - 40.1 weeks
FL Menstrual Age FL Menstrual Age
(mm) (weeks + days) (mm) (weeks + days)
20 17 + 1 48 27 + 1
21 17 + 3 49 27 + 4
22 17 + 5 50 27 + 6
23 17 + 7 51 28 + 3
24 18 + 2 52 28 + 5
25 18 + 4 53 29 + 2
26 18 + 7 54 29 + 5
27 19 + 2 55 30 + 1
28 19 + 5 56 30 + 4
29 19 + 7 57 30 + 6
58 31 + 3
30 20 + 3 59 31 + 6
31 20 + 5
32 21 + 1 60 32 + 2
33 21 + 3 61 32 + 5
34 21 + 5 62 33 + 2
35 22 + 1 63 33 + 4
36 22 + 4 64 34 + 1
37 22 + 6 65 34 + 4
38 23 + 2 66 35 + 1
39 23 + 4 67 35 + 4
68 36 + 1
40 23 + 7 69 36 + 5
41 24 + 3
42 24 + 5 70 37 + 2
43 25 + 1 71 37 + 5
44 25 + 4 72 38 + 2
45 25 + 6 73 38 + 6
46 26 + 2 74 39 + 4
47 26 + 5 75 40 + 1
Regression Equation:
MA Coeff 2SD Coeff
Q0 = 10.8592900 Q0 = 1.5059900
Q1 = 3.6392690 Q1 = – 0.1308938
Q2 = –0.6200159 Q2 = 0.0086599
Q3 = 0.2392270 Q3 = – 0.0001130
Q4 = – 0.0338586 Q4 = 0.0000000
Q5 = 0.0018145 Q5 = 0.0000000
Limits
MIN = 17.1 wks
MAX = 40.1 wks
Reference: Hansmann, M., et. al. 1985. Ultrasound Diagnosis in
Obstetrics and Gynecology. Springer-Verlag.
FL Chart, Hohler
9.2 - 44.5 weeks
FL Menstrual Age FL Menstrual Age
(mm) (weeks) (mm) (weeks)
0 9.2 44 24.0
1 9.4 45 24.4
2 9.7 46 24.8
3 10.0 47 25.3
4 10.3 48 25.7
5 10.6 49 26.1
6 10.8
7 11.1 50 26.5
8 11.4 51 27.0
9 11.7 52 27.4
53 27.8
10 12.0 54 28.3
11 12.3 55 28.7
12 12.6 56 29.1
13 12.9 57 29.6
14 13.2 58 30.0
15 13.5 59 30.5
16 13.9
17 14.2 60 31.0
18 14.5 61 31.4
19 14.8 62 31.9
63 32.4
20 15.2 64 32.8
21 15.5 65 33.3
22 15.8 66 33.8
23 16.2 67 34.3
24 16.5 68 34.7
25 16.9 69 35.2
26 17.2
27 17.6 70 35.7
28 17.9 71 36.2
29 18.3 72 36.7
73 37.2
30 18.6 74 37.7
31 19.0 75 38.2
32 19.4 76 38.7
33 19.7 77 39.2
34 20.1 78 39.7
35 20.5 79 40.3
36 20.9
37 21.2 80 40.8
38 21.6 81 41.3
39 22.0 82 41.8
83 42.4
40 22.4 84 42.9
41 22.8 85 43.4
42 23.2 86 44.0
43 23.6 87 44.5
Regression Equation:
MA Coeff 2SD Coeff
Q0 = 9.174068 Q0 = 0.0000000
Q1 = 2.670895 Q1 = 0.0000000
Q2 = 0.159947 Q2 = 0.0000000
Q3 = 0.000000 Q3 = 0.0000000
Q4 = 0.000000 Q4 = 0.0000000
Q5 = 0.000000 Q5 = 0.0000000
Limits
MIN = 9.2 wks
MAX = 44.5 wks
Reference: Hohler, Charles, M.D., Miami, Florida, June, 1982.
FL Chart, Jeanty
12.6 - 40 weeks
FL Menstrual Age FL Menstrual Age
(mm) (wks + days) (mm) (wks + days)
10 12 + 4 45 25
11 12 + 6 46 25 + 3
12 13 + 2 47 25 + 6
13 13 + 4 48 26 + 1
14 13 + 6 49 26 + 4
15 14 + 1 50 27
16 14 + 4 51 27 + 3
17 14 + 6 52 27 + 6
18 15 + 1 53 28 + 1
19 15 + 4 54 28 + 4
20 15 + 6 55 29 + 1
21 16 + 2 56 29 + 4
22 16 + 4 57 29 + 6
23 16 + 6 58 30 + 2
24 17 + 2 59 30 + 5
25 17 + 4 60 31 + 1
26 18 61 31 + 4
27 18 + 2 62 32
28 18 + 5 63 32 + 3
29 19 64 32 + 6
30 19 + 3 65 33 + 2
31 19 + 5 66 33 + 5
32 20 + 1 67 34 + 1
33 20 + 4 68 34 + 4
34 20 + 6 69 35
35 21 + 1 70 35 + 4
36 21 + 4 71 35 + 8
37 22 72 36 + 3
38 22 + 3 73 36 + 6
39 22 + 5 74 37 + 2
40 23 + 1 75 37 + 5
41 23 + 4 76 38 + 1
42 23 + 6 77 38 + 4
43 24 + 2 78 39 + 1
44 24 + 5 79 39 + 4
80 40
Regression Equation:
MA Coeff 2SD Coeff
Q0 = 9.4211530 Q0 = 0.0000000
Q1 = 3.0516800 Q1 = 0.0000000
Q2 = 0.0890988 Q2 = 0.0000000
Q3 = 0.0009513 Q3 = 0.0000000
Q4 = 0.0000000 Q4 = 0.0000000
Q5 = 0.0000000 Q5 = 0.0000000
Limits
MIN = 12.6 wks
MAX = 40.0 wks
Reference: Jeanty, P. and R. Romero. 1984. Obstetrical Ultrasound. McGraw Hill.
FL Chart, O’Brien
12.0 - 40.0 weeks
FL Menstrual Age FL Menstrual Age
(mm) (wks + days) (mm) (wks + days)
10 12 + 0 46 25 + 0
11 12 + 3 47 25 + 3
12 12 + 6 48 26 + 0
13 13 + 1 49 26 + 4
14 13 + 4
15 13 + 6 50 27 + 0
16 14 + 1 51 27 + 2
17 14 + 4 52 27 + 5
18 14 + 6 53 28 + 0
19 15 + 2 54 28 + 3
55 29 + 0
20 15 + 3 56 29 + 3
21 15 + 6 57 30 + 0
22 16 + 1 58 30 + 2
23 16 + 4 59 30 + 5
24 16 + 6
25 17 + 0 60 31 + 0
26 17 + 2 61 31 + 4
27 17 + 4 62 32 + 0
28 18 + 0 63 32 + 3
29 18 + 2 64 33 + 0
65 33 + 3
30 18 + 4 66 34 + 0
31 18 + 6 67 34 + 4
32 19 + 3 68 35 + 0
33 19 + 5 69 35 + 2
34 20 + 0
35 20 + 2 70 35 + 5
36 20 + 5 71 36 + 0
37 21 + 0 72 36 + 3
38 21 + 2 73 37 + 0
39 21 + 5 74 37 + 3
75 38 + 0
40 22 + 0 76 38 + 3
41 22 + 4 77 39 + 0
42 23 + 0 78 39 + 2
43 23 + 3 79 39 + 5
44 24 + 0 80 40 + 0
45 24 + 3
Regression Equation:
MA Coeff 2SD Coeff
Q0 = 5.184726 Q0 = 0.0000000
Q1 = 9.844899 Q1 = 0.0000000
Q2 = –3.993980 Q2 = 0.0000000
Q3 = 1.041302 Q3 = 0.0000000
Q4 = – 0.116949 Q4 = 0.0000000
Q5 = 0.004815 Q5 = 0.0000000
Limits
MIN = 12.0 wks
MAX = 40.0 wks
Reference: Data adapted from composite mean values for O’Brien (American Journal of Obstetrics and
Gynecology, 1981) from 12 to 23 weeks and for Hohler (submitted to AJOG for publication)
from 23 to 40 weeks.
FL Chart, Queenan
14.0 weeks - 40.0 weeks
FL Menstrual Age
(mm) (wks + days)
16.6 14
19.9 15
22.0 16
25.2 17
29.6 18
32.4 19
34.8 20
37.5 21
40.9 22
43.5 23
46.4 24
48.0 25
51.1 26
53.0 27
54.4 28
57.3 29
58.7 30
61.5 31
62.8 32
64.9 33
65.7 34
67.7 35
69.5 36
70.8 37
71.8 38
74.2 39
75.4 40
Regression Equation:
MA Coeff 2SD Coeff
Q0 = 6.511794 Q0 = 0.0000000
Q1 = 5.909238 Q1 = 0.0000000
Q2 = –1.108480 Q2 = 0.0000000
Q3 = 0.172456 Q3 = 0.0000000
Q4 = –0.006786 Q4 = 0.0000000
Q5 = 0.000000 Q5 = 0.0000000
Limits
MIN = 14.0 wks
MAX = 40.0 wks
Reference: O’Brien, G.D., J.T. Queenan et al. 1981. Femur Length to Weeks Gestation for 14 to 40
Weeks. American Journal of Obstetrics and Gynecology, 141: 833.
8 11
9 12
10 13
16 14
16 15
21 16
24 17
27 18
28 19
33 20
35 21
38 22
42 23
44 24
47 25
51 26
54 27
58 28
57 29
61 30
62 31
63 32
67 33
68 34
71 35
74 36
75 37
78 38
78 39
82 40
Regression Equation:
MA Coeff 2SD Coeff
Q0 = 6.3629150 Q0 = 0.0000000
Q1 = 8.1331350 Q1 = 0.0000000
Q2 = –2.6364520 Q2 = 0.0000000
Q3 = 0.5923926 Q3 = 0.0000000
Q4 = –0.0558040 Q4 = 0.0000000
Q5 = 0.0018668 Q5 = 0.0000000
Limits
MIN = 11.0 wks
MAX = 40.0 wks
Reference: Mercer, B.M., et. al. 1987. Fetal foot length as a predictor of gestational age.
American Journal of Obstetrics and Gynecology. 156:350.
Regression Equation:
MA Coeff 2SD Coeff
Q0 = 4.2980280 Q0 = 0.0000000
Q1 = 1.6067070 Q1 = 0.0000000
Q2 = –0.0653561 Q2 = 0.0000000
Q3 = 0.0058119 Q3 = 0.0000000
Q4 = 0.0000000 Q4 = 0.0000000
Q5 = 0.0000000 Q5 = 0.0000000
Limits
MIN = 6.0 wks
MAX = 14.0 wks
Reference: Hansmann, M., et. al. 1985. Ultrasound Diagnosis in Obstetrics and Gynecology.
Springer-Verlag.
Regression Equation:
MA Coeff 2SD Coeff
Q0 = 3.622507 Q0 = 0.0000000
Q1 = 1.425010 Q1 = 0.0000000
Q2 = 0.000000 Q2 = 0.0000000
Q3 = 0.000000 Q3 = 0.0000000
Q4 = 0.000000 Q4 = 0.0000000
Q5 = 0.000000 Q5 = 0.0000000
Limits
MIN = 5.0 wks
MAX = 12.2 wks
Reference: Hellman, L.M., et. al. 1969. Growth and Development of the Human Fetus Prior to the
Twentieth Week of Gestation. American Journal of Obstetrics and Gynecology. 103: 784-800.
HC Chart, Campbell
14 - 40 weeks
HC Menstrual Age
(mm) (weeks)
110 14
131 16
156 18
180 20
204 22
226 24
250 26
270 28
288 30
304 32
318 34
330 36
340 38
348 40
Regression Equation:
MA Coeff 2SD Coeff
Q0 = –5.415342 Q0 = 0.0000000
Q1 = 2.613817 Q1 = 0.0000000
Q2 = –0.096826 Q2 = 0.0000000
Q3 = 0.001693 Q3 = 0.0000000
Q4 = 0.000000 Q4 = 0.0000000
Q5 = 0.000000 Q5 = 0.0000000
–5.415342+2.613817*HC+–0.096826*HC^2+0.001693*HC^3
Limits
MIN = 14.0 wks11.0 cm
MAX = 40.0 wks34.8 cm
HC Chart, Hadlock
12.2 - 41.9 weeks
HC MA 2 Std HC MA 2 Std HC MA 2 Std
(mm) (weeks) Dev (mm) (weeks) Dev (mm) (weeks) Dev
HC Chart, Hadlock
(continued)
HC MA 2 Std HC MA 2 Std HC MA 2 Std
(mm) (weeks) Dev (mm) (weeks) Dev (mm) (weeks) Dev
HC Chart, Hadlock
(continued)
HC MA 2 Std HC MA 2 Std HC MA 2 Std
(mm) (weeks) Dev (mm) (weeks) Dev (mm) (weeks) Dev
Regression Equation:
MA Coeff 2SD Coeff
Q0 = 8.9600000 Q0 = 0.0000000
Q1 = 0.5400000 Q1 = 0.0000000
Q2 = 0.0000000 Q2 = 0.0000000
Q3 = 0.0003000 Q3 = 0.0000000
Q4 = 0.0000000 Q4 = 0.0000000
Q5 = 0.0000000 Q5 = 0.0000000
Limits
MIN = 12.2 wks
MAX = 42.0 wks
Reference: Hadlock, F.P. et al. 1984. Estimating Fetal age: Computer-Assisted Analysis of Multiple
Fetal Growth Parameters. Radiology 152 (no.2) 499.
HC Chart, Hansmann
17.9 - 41.6 weeks
HC Menstrual Age
(mm) (weeks + days)
140 17 + 6
150 18 + 5
160 19 + 4
170 20 + 3
180 21 + 2
190 22 + 1
200 22 + 6
210 23 + 5
220 24 + 4
230 25 + 3
240 26 + 2
250 27 + 2
260 28 + 1
270 29 + 1
280 30 + 1
290 31 + 2
300 32 + 3
310 33 + 6
320 35 + 2
330 36 + 6
340 39 + 1
350 41 + 4
Regression Equation:
MA Coeff 2SD Coeff
Q0 = –12.5869800 Q0 = 0.0000000
Q1 = 3.6772550 Q1 = 0.0000000
Q2 = –0.1398529 Q2 = 0.0000000
Q3 = 0.0022478 Q3 = 0.0000000
Q4 = 0.0000000 Q4 = 0.0000000
Q5 = 0.0000000 Q5 = 0.0000000
Limits
MIN = 17.9 wks
MAX = 41.6 wks
Reference: Hansmann, M., et. al. 1985. Ultrasound Diagnosis in Obstetrics and Gynecology.
Springer-Verlag.
HC Chart, Hoffbauer
12 - 40 weeks
HC Menstrual Age
(mm) (weeks)
60 12
75 13
90 14
105 15
120 16
135 17
150 18
160 19
180 20
190 21
200 22
210 23
220 24
230 25
240 26
250 27
260 28
270 29
280 30
290 31
300 32
305 33
310 34
320 35
330 36
335 37
340 38
350 39
360 40
Regression Equation
MA Coeff 2SD Coeff
Q0 = 8.9079530 Q0 = 0.0000000
Q1 = 0.5020671 Q1 = 0.0000000
Q2 = 0.0046350 Q2 = 0.0000000
Q3 = 0.0001522 Q3 = 0.0000000
Q4 = 0.0000000 Q4 = 0.0000000
Q5 = 0.0000000 Q5 = 0.0000000
Limits
MIN = 12.0 wks
MAX = 40.0 wks
Reference: Hoffbauer H., et al. 1979. Control of Fetal Development with Multiple Ultrasonic Body
Measures. Contr. Gynec. Obstet. 6:147.
HC Chart, Jeanty
13.3 - 41.7 weeks
HC Menstrual Age HC Menstrual Age
(mm) (weeks + days) (mm) (weeks + days)
80 13 + 2 225 24 + 3
85 13 + 5 230 24 + 6
90 13 + 7 235 25 + 3
95 14 + 2 240 25 + 8
100 14 + 4 245 26 + 3
105 14 + 6 250 26 + 6
110 15 + 2 255 27 + 3
115 15 + 4 260 28 + 0
120 15 + 6 265 28 + 4
125 16 + 2 270 29 + 1
130 16 + 4 275 29 + 5
135 16 + 6 280 30 + 2
140 17 + 2 285 30 + 7
145 17 + 4 290 31 + 4
150 17 + 7 295 32 + 1
155 18 + 3 300 32 + 6
160 18 + 5 305 33 + 4
165 19 + 1 310 34 + 1
170 19 + 4 315 34 + 8
175 19 + 6 320 35 + 4
180 20 + 2 325 36 + 2
185 20 + 5 330 37 + 0
190 21 + 1 335 37 + 5
195 21 + 4 340 38 + 4
200 22 + 0 345 39 + 2
205 22 + 3 350 40 + 0
210 22 + 7 355 40 + 6
215 23 + 3 360 41 + 5
220 23 + 6
Regression Equation:
MA Coeff 2SD Coeff
Q0 = 8.8178080 Q0 = 0.0000000
Q1 = 0.5504550 Q1 = 0.0000000
Q2 = – 0.0001829 Q2 = 0.0000000
Q3 = 0.0002846 Q3 = 0.0000000
Q4 = – 0.0000000 Q4 = 0.0000000
Q5 = 0.0000000 Q5 = 0.0000000
Limits
MIN = 13.3 wks
MAX = 41.7 wks
Reference: Jeanty, P. and Romero, R.: Obstetrical Ultrasound. Copyright 1984.
10 12 + 4 40 24 + 2
11 12 + 6 41 24 + 6
12 13 + 1 42 25 + 2
13 13 + 4 43 25 + 5
14 13 + 6 44 26 + 1
15 14 + 1 45 26 + 5
16 14 + 4 46 27 + 1
17 14 + 6 47 27 + 5
18 15 + 1 48 28 + 1
19 15 + 4 49 28 + 6
20 15 + 6 50 29 + 2
21 16 + 2 51 29 + 6
22 16 + 5 52 30 + 2
23 17 + 1 53 30 + 6
24 17 + 3 54 31 + 3
25 17 + 6 55 32 + 0
26 18 + 1 56 32 + 4
27 18 + 4 57 33 + 1
28 19 + 0 58 33 + 4
29 19 + 3 59 34 + 1
30 19 + 6 60 34 + 6
31 20 + 2 61 35 + 2
32 20 + 5 62 35 + 6
33 21 + 1 63 36 + 4
34 21 + 4 64 37 + 1
35 22 + 0 65 37 + 5
36 22 + 4 66 38 + 2
37 22 + 6 67 38 + 6
38 23 + 3 68 39 + 4
39 23 + 6 69 40 + 1
Regression Equation:
MA Coeff 2SD Coeff
Q0 = 9.8149570 Q0 = 2.5660180
Q1 = 2.4542960 Q1 = 0.0196600
Q2 = 0.3152320 Q2 = –0.0003650
Q3 = –0.0068960 Q3 = 0.0000000
Q4 = 0.0002902 Q4 = 0.0000000
Q5 = 0.0000000 Q5 = 0.0000000
Limits
MIN = 12.6 wks
MAX = 40.1 wks
Reference: Jeanty, P. and R. Romero. 1984. Obstetrical Ultrasound. McGraw Hill.
Regression Equation:
MA Coeff 2SD Coeff
Q0 = 5.635285 Q0 = 0.0000000
Q1 = 4.391298 Q1 = 0.0000000
Q2 = 0.064272 Q2 = 0.0000000
Q3 = –0.102344 Q3 = 0.0000000
Q4 = 0.022172 Q4 = 0.0000000
Q5 = 0.000000 Q5 = 0.0000000
Limits
MIN = 11.6 wks
MAX = 39.8 wks
Reference: Mayden, K.L., et. al. 1982. Orbital diameters: A new Parameter for Prenatal Diagnosis and
Dating. American Journal of Obstetrics and Gynecology. 144: 289-97.
Regression Equation:
MA Coeff 2SD Coeff
Q0 = 6.0456510 Q0 = 0.0000000
Q1 = 1.0880140 Q1 = 0.0000000
Q2 = 0.0003387 Q2 = 0.0000000
Q3 = 0.0000000 Q3 = 0.0000000
Q4 = 0.0000000 Q4 = 0.0000000
Q5 = 0.0000000 Q5 = 0.0000000
Limits
MIN = 16.0 wks
MAX = 40.0 wks
Reference: Romero. 1987. Journal of OB Gyn. 158:1069, 1072.
30 16 + 3 60 25 + 6 90 36 + 1
31 16 + 5 61 26 + 1 91 36 + 3
32 17 + 1 62 26 + 3 92 36 + 5
33 17 + 3 63 26 + 5 93 37 + 1
34 17 + 5 64 27 + 1 94 37 + 4
35 17 + 7 65 27 + 3 95 37 + 7
36 18 + 2 66 27 + 5 96 38 + 2
37 18 + 4 67 28 + 1 97 38 + 5
38 18 + 6 68 28 + 3 98 39 + 1
39 19 + 1 69 28 + 5 99 39 + 4
40 19 + 3 70 29 + 1 100 39 + 7
41 19 + 6 71 29 + 3 101 40 + 3
42 20 + 1 72 29 + 5 102 40 + 6
43 20 + 3 73 30+ 1 103 41 + 3
44 20 + 5 74 30 + 3
45 20 + 7 75 30 + 6
46 21 + 2 76 31 + 1
47 21 + 4 77 31 + 3
48 21 + 7 78 31 + 6
49 22 + 2 79 32 + 1
Regression Equation:
MA Coeff 2SD Coeff
Q0 = 6.9634960 Q0 = 0.9180432
Q1 = 3.8298530 Q1 = –0.0336696
Q2 = –0.4430650 Q2 = 0.0030782
Q3 = 0.1010238 Q3 = 0.0000000
Q4 = –0.0099702 Q4 = 0.0000000
Q5 = 0.0003773 Q5 = 0.0000000
Limits
MIN = 13.6 wks
MAX = 41.4 wks
Reference: Hansmann, M., et. al. 1985. Ultrasound Diagnosis in Obstetrics and Gynecology.
Springer-Verlag.
10 13 + 3 40 25 + 2
11 13 + 5 41 25 + 5
12 14 + 1 42 26 + 1
13 14 + 3 43 26 + 4
14 14 + 6 44 27 + 1
15 15 + 1 45 27 + 4
16 15 + 4 46 28 + 0
17 15 + 6 47 28 + 4
18 16 + 1 48 29 + 0
19 16 + 4 49 29 + 3
20 17 + 0 50 29 + 6
21 17 + 3 51 30 + 3
22 17 + 6 52 30 + 6
23 18 + 1 53 31 + 3
24 18 + 4 54 31 + 6
25 18 + 6 55 32 + 3
26 19 + 2 56 32 + 6
27 19 + 5 57 33 + 3
28 20 + 1 58 33 + 6
29 20 + 4 59 34 + 4
30 21 + 0 60 34 + 6
31 21 + 3 61 35 + 3
32 21 + 6 62 35 + 6
33 22 + 1 63 36 + 4
34 22 + 4 64 37 + 0
35 23 + 1 65 37 + 4
36 23 + 4 66 38 + 0
37 23 + 6 67 38 + 4
38 24 + 3 68 39 + 1
39 24 + 6 69 39 + 5
Regression Equation:
MA Coeff 2SD Coeff
Q0 = 10.2870000 Q0 = 0.0000000
Q1 = 2.8873990 Q1 = 0.0000000
Q2 = 0.2587258 Q2 = 0.0000000
Q3 = -0.0139916 Q3 = 0.0000000
Q4 = 0.0007752 Q4 = 0.0000000
Q5 = 0.0000000 Q5 = 0.0000000
Limits
MIN = 11.0 wks
MAX = 40.0 wks
Reference: Jeanty, P., et. al. February, 1984. Estimation of Gestational Age from Measurement of Fetal
Long Bones. Journal of Ultrasound Medicine. 3: 75-79.
9 13
10 14
13 15
16 16
18 17
22 18
25 19
27 20
30 21
32 22
36 23
37 24
40 25
42 26
44 27
45 28
46 29
48 30
51 31
52 32
54 33
57 34
58 35
60 36
61 37
62 38
64 39
65 40
66 41
68 42
Regression Equation:
MA Coeff 2SD Coeff
Q0 = 4.6722820 Q0 = 0.0000000
Q1 = 14.5027000 Q1 = 0.0000000
Q2 = –7.3699760 Q2 = 0.0000000
Q3 = 2.1782100 Q3 = 0.0000000
Q4 = –0.2874230 Q4 = 0.0000000
Q5 = 0.0144052 Q5 = 0.0000000
Limits
MIN = 13.0 wks
MAX = 42.0 wks
Reference: Merz, E., et. al. Ultrasonic Mensuration of Fetal Limb Bones in the Second and Third
Trimester. J. Clin. Ultrasound. 15:175-183, March-April 1987.
10 13 + 1 38 25 + 1
11 13 + 4 39 25 + 4
12 13 + 6
13 14 + 1 40 26 + 1
14 14 + 4 41 26 + 5
15 15 + 0 42 27 + 1
16 15 + 3 43 27 + 5
17 15 + 5 44 28 + 2
18 16 + 1 45 28 + 6
19 16 + 4 46 29 + 3
47 29 + 6
20 16 + 6 48 30 + 4
21 17 + 2 49 31 + 1
22 17 + 5
23 18 + 1 50 31 + 4
24 18 + 4 51 32 + 1
25 19 + 0 52 32 + 6
26 19 + 3 53 33 + 3
27 19 + 6 54 34 + 0
28 20 + 2 55 34 + 4
29 20 + 6 56 35 + 1
57 35 + 6
30 21 + 1 58 36 + 3
31 21 + 5 59 37 + 1
32 22 + 1
33 22 + 5 60 37 + 5
34 23 + 1 61 38 + 2
35 23 + 4 62 39 + 0
36 24 + 1 63 39 + 4
37 24 + 4 64 40 + 2
Regression Equation:
MA Coeff 2SD Coeff
Q0 = 9.7973180 Q0 = 3.0372120
Q1 = 3.2535710 Q1 = 0.0026310
Q2 = 0.0428870 Q2 = 0.0000000
Q3 = 0.0713840 Q3 = 0.0000000
Q4 = –0.0092650 Q4 = 0.0000000
Q5 = 0.0004399 Q5 = 0.0000000
Limits
MIN = 13.1 wks
MAX = 40.3 wks
Reference: Jeanty, P. and R. Romero. 1984. Obstetrical Ultrasound. McGraw Hill.
OZ
LBS 0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
0 - 28 57 85 113 142 170 198 255 284 312 340 369 397 425
227
1 454 482 510 539 567 595 624 652 680 709 737 765 794 822 850 879
2 907 936 964 992 1021 1049 1077 1106 1134 1162 1191 1219 1247 1276 1304 1332
3 1361 1389 1417 1446 1474 1503 1531 1559 1588 1616 1644 1673 1701 1729 1758 1786
4 1814 1843 1871 1899 1928 1956 1984 2013 2041 2070 2098 2126 2155 2183 2211 2240
5 2268 2296 2325 2353 2381 2410 2438 2466 2495 2523 2551 2580 2608 2637 2665 2693
6 2722 2750 2778 2807 2835 2863 2892 2920 2948 2977 3005 3033 3062 3090 3118 3147
7 3175 3203 3232 3260 3289 3317 3345 3374 3402 3430 3459 3487 3515 3544 3572 3600
8 3629 3657 3685 3714 3742 3770 3799 3827 3856 3884 3912 3941 3969 3997 4026 4054
9 4082 4111 4139 4167 4196 4224 4252 4281 4309 4337 4366 4394 4423 4451 4479 4508
10 4536 4564 4593 4621 4649 4678 4706 4734 4763 4791 4819 4848 4876 4904 4933 4961
11 4989 5018 5046 5075 5103 5131 5160 5188 5216 5245 5273 5301 5330 5358 5386 5415
12 5443 5471 5500 5528 5556 5585 5613 5642 5670 5698 5727 5755 5783 5812 5840 5868
13 5897 5925 5953 5982 6010 6038 6067 6095 6123 6152 6180 6209 6237 6265 6294 6322
14 6350 6379 6407 6435 6464 6492 6520 6549 6577 6605 6634 6662 6690 6719 6747 6776
No part of this publication may be reproduced or transmitted in any form by any means including photo-
copying or recording without written permission of the copyright owner. Printed in the U.S.A.
The A.I.U.M. Executive Office is located at 14750 Sweitzer Lane, Suite 100, Laurel, MD 20707–5906.
Table of Contents
Preface ................................................................................................................................................ iv
Introduction ......................................................................................................................................... v
Acknowledgements ............................................................................................................................ vi
Conclusion ............................................................................................................................. 40
iii
Preface
With the availability of an output display in some present and in future diagnostic ultrasound
equipment and the potential for higher output capabilities within these devices, it is incumbent upon the
user to be knowledgeable of the uses of this equipment and the potential for ultrasound-induced bioef-
fects. The responsibility for patient safety is falling more heavily upon the ultrasound equipment user’s
shoulders and the need for an educational background in these uses and bioeffects is evident. In other
words, there is a shift in responsibility for patient safety from the manufacturer to the user. In this
regard, this tripartite brochure has been generated to provide the user with a working background and
general principles that will provide for the understanding of the purpose and use of the Output Display
Standard and how this display can be used to obtain diagnostic information with ultrasound exposure as
low as reasonably achievable. The user education requirement represents a new level of responsibility
that will permit increased ultrasound diagnostic capabilities within the context of user controlled ultra-
sound exposure. Information regarding ALARA and possible ultrasound bioeffects described in this
brochure also applies to equipment without an output display.
iv
Introduction
A new feature, called an output display, is becoming available on some recently introduced and
future diagnostic ultrasound equipment. The output display provides the user an indication of the poten-
tial for bioeffects that might be caused by the ultrasound energy being emitted. With this information,
users can better control the diagnostic ultrasound equipment and examination to assure that needed
diagnostic information is obtained with a minimum of risk to the patient.
To get the most benefit from the output display, the user should have a basic understanding of the
nature of ultrasound-induced bioeffects, how to conduct an exam that minimizes the potential for bioef-
fects, and how to operate the controls of the equipment used in the exam.
This brochure is divided into three parts. Part One describes ultrasound-induced bioeffects and
why we should be concerned about them. Part Two describes the risks and benefits of conducting diag-
nostic examinations and introduces the concept of ALARA, that is, ultrasound exposure As Low As
Reasonably Achievable. Using ALARA, we can obtain needed diagnostic information with minimum
risk to the patient. Part Three describes how to implement ALARA on equipment with and without an
output display. With an output display, we have the best information about the potential for bioeffects
and can make the best decisions.
Each manufacturer’s equipment has somewhat different control features. This brochure can only
provide general principles about ALARA and diagnostic ultrasound equipment. Please refer to the user
documentation for your particular equipment to learn the details of its particular controls and output
displays.
v
Acknowledgements
The development of this Ultrasound Education Program brochure went through a number of style
and format changes and involved dedicated professionals from a number of organizations over the past
three years. Initially, three videotapes were planned with the creation of three scripts. What finally
emerged is this brochure. There are many individuals to thank. Special recognition is given to Mr. Chas
Burr for his extensive revisions to the final content of the text. Without their assistance, this brochure
would not have been possible.
1
2
Chapter One
Is It Safe?
Issues Addressed:
• Why it is important to know ultrasound physics
• What dose-effect studies tell us
• Mechanisms of ultrasound-induced biological effects
• History of ultrasound
• Prudent use
Q. Everyone thinks that ultrasound is safe. We keep hearing, “no known Everyone thinks ultrasound is
instance of human injury as a result of exposure to diagnostic safe.
ultrasound.” So why do we have to learn about biophysics and
bioeffects?
A. When ultrasound propagates through human tissue, there is a potential There is a potential risk.
for tissue damage. There has been much research aimed at
understanding and evaluating the potential for ultrasound to cause
tissue injury. Through these studies, we are trying to learn what
causes ultrasonic bioeffects and apply that information to diagnostic
ultrasound. Many studies are dose-effect studies. These laboratory
studies give us two things: First, they provide an opportunity to use
much higher dosage levels than those currently used in a diagnostic
ultrasound exam to really test the safety of ultrasound, and second,
they permit a detailed study of mechanisms thought to be responsible
for bioeffects.
A. So far, we’ve deduced that two mechanisms are known to alter Thermal Mechanism
biological systems. One, called the “Thermal Mechanism,” refers to Nonthermal Mechanism
heating of soft tissue and bone. The other, “Nonthermal,” involves
mechanical phenomena such as cavitation, although nonthermal
mechanisms are more than cavitation alone. You can think of
cavitation as the interaction of ultrasound with tiny bubbles in tissue
and liquids.
3
History of ultrasound Q. How long have we known of the potential hazards of ultrasound?
If there’s a potential for Q. If there’s a potential for bioeffects, why do we use ultrasound?
bioeffects . . .
No patient injury has ever A. Most important, we use ultrasound because of its many diagnostic uses
been reported from and benefits. Although there may be a risk, there has never been a
diagnostic ultrasound. documented instance of a patient being injured from this diagnostic
modality.
Diagnostic ultrasound A. As the uses of medical devices have grown and more application areas
equipment is regulated by and equipment have been developed, regulations have been enacted to
the FDA. provide for patient safety concurrent with equipment development. In
1976, the Medical Device Amendments to the Food, Drug, and
Cosmetic Act were enacted requiring the Food and Drug
Administration (FDA) to regulate all medical devices, including
diagnostic ultrasound equipment. The FDA has required manufacturers
of diagnostic ultrasound equipment to keep acoustic output below that
of machines on the market before 1976, the year the amendments were
enacted. Manufacturers bringing new products to market must
compare the various performance characteristics of ultrasound
equipment, including acoustic output, to devices previously approved
for marketing.
4
Within these “limits,” ultrasound has shown itself to be a safe and
effective diagnostic tool for medical application. But it is important
BIOEFFECTS & SAFETY
of Diagnostic Ultrasound
to remember that the pre-1976 output levels are based in history, not
on scientific safety evaluations.
“Diagnostic ultrasound has been in use since the late 1950s. Given its
known benefits and recognized efficacy for medical diagnosis,
including use during human pregnancy, the American Institute of
Ultrasound in Medicine herein addresses the clinical safety of such
use: No confirmed biological effects on patients or instrument
operators caused by exposure at intensities typical of present “. . . the benefits to patients of
the prudent use of diagnostic
diagnostic ultrasound instruments have ever been reported. Although ultrasound outweigh the risks,
the possibility exists that such biological effects may be identified in if any, that may be present.”
the future, current data indicate that the benefits to patients of the
prudent use of diagnostic ultrasound outweigh the risks, if any, that
may be present.”
Q. Why is there more discussion of ultrasound safety now than in the History of ultrasound in
past? medicine
A. The question of safety is being discussed more because more and Higher outputs bring
more applications are being found, and the industry is producing potentially greater risk.
technically sophisticated devices that provide more diagnostic
information. Current dialogue among the medical community,
manufacturers, and the FDA suggests that new standards recently
developed should allow higher outputs for greater diagnostic
capability. This will improve some imaging and Doppler situations,
but with greater risk and greater operator responsibility.
5
body, such as the female breast and male pelvis. By the early 1960s
most of the basic ultrasound applications used today had been
attempted, although with much less diagnostic content than today.
Clinical use continued to grow during the 1970s with the introduction
of real-time scanning.
Early exams were conducted entirely through the skin surface, but
intracavitary and intraoperative applications have undergone a recent
surge as manufacturers and clinicians seek to expand the diagnostic
potential of ultrasound. Today, the clinical uses for ultrasound are
many and varied, and diagnostic ultrasound is one of the fastest
growing imaging techniques in medicine. Surveys in the United States
indicate that a very high percentage of pregnant women are scanned
to obtain fetal health information. There are about 100 thousand
medical ultrasound scanners in use worldwide. This equipment
handles millions of examinations each year. And, the number
continues to grow.
6
Chapter Two
Thermal Bioeffects
Issues Addressed:
• Focused and unfocused ultrasound fields
• Spatial and temporal considerations
• Attenuation, absorption, and scattering
• Soft tissue, layered and fetal bone models
• Soft tissue, layered and fetal bone heating
• Axial temperature increase profiles
A. Focusing concentrates the power in the beam on a small area, thereby Power
Intensity =
improving image lateral resolution, but also causing higher intensities Area
and the potential for higher temperatures.
7
Temporal considerations A. An important aspect is time.
and more silence, and on and on. During the pulse the acoustic
intensity is high, but during the silence the intensity is zero.
time
If we take the entire repeating time period, both the pulse and the
silence, and average the intensity of the ultrasound over time, we come
Pulsed pressure waveform
up with a temporal-average intensity that may be a thousand times
smaller than the instantaneous or temporal-peak intensity that occurs
once during the pulse. Bioeffects resulting from temperature increases
depend, in part, on the temporal-average intensity.
intensity
temperature to rise, and the longer the exposure duration, the greater
TA
the possibility of a biological effect.
time
Temporal-average (TA) Q. What causes the temperature rise in tissue during ultrasonic exposure?
and temporal-peak (TP)
intensities A. The absorption of energy. During an exam, much of the ultrasound
Ultrasound exposure duration energy is absorbed by body tissue. If the rate of energy deposition in a
Line drawing 14-2
particular region exceeds the body’s ability to dissipate the heat, the
local temperature will rise.
Attenuation Absorption and attenuation are often confused. Attenuation is the loss
1. Absorption = energy of energy from the propagated ultrasound wave. There are two causes
converted to heat for attenuation: Absorption and scattering. Absorption is the
2. Scattering = redirection of
ultrasound
conversion of ultrasonic energy into heat; whereas, scattering is the
redirection of the ultrasound away from the direction it was originally
Line drawing 15-1
traveling.
8
The extent depends on the tissue, on what we call tissue absorption Attenuation coefficient and
characteristics. absorption coefficient have
the same units—dB/cm or dB/
cm-MHz
A specific way in which tissue absorption characteristics are
quantified is with the “Absorption Coefficient.” The absorption
coefficient is expressed in decibels per centimeter. Since absorption
coefficient is directly proportional to ultrasonic frequency, the
Increasing Attenuation
coefficient is often normalized to frequency and represented as Coefficient
decibels per centimeter per megahertz. Absorption coefficients are Water
very dependent on the organ or tissue type that is being imaged. Biological fluids
Soft tissues
Q. Let’s get some examples. What’s the absorption coefficient of, say, Skin and cartilage
Fetal bone
fluids, like amniotic fluid, blood, and urine? Adult bone
A. Almost zero. These fluids absorb very little ultrasonic energy. That
means the ultrasound goes through the fluid with very little decrease.
And there’s little temperature elevation in the fluid.
A. Bone. Its absorption coefficient is very high. Dense bone absorbs the
energy very quickly and causes the temperature to rise rapidly. Adult
bone absorbs nearly all of the acoustic energy impinging on it. Fetal
bone absorption coefficients vary greatly depending on the degree of
ossification.
A. Soft tissue. Tissues vary in density depending on the particular organ, Homogeneous soft tissue
but the density doesn’t vary much within a organ. We call it soft to model
distinguish it from hard tissue such as bone. It’s also true that the
tissue density within a particular organ is not always the same. But,
for our purposes we assume that attenuation and absorption are
uniform throughout the organ. We call this a homogeneous soft tissue
model.
A. The higher the frequency, the higher the absorption. What that means
to operators is that a higher-frequency transducer will not allow us to
“see” as far into the body.
Q. Does that mean that higher-frequency transducers create more heat? Higher Frequency = Increased
Absorption, Reduced
Penetration, Possible Near
A. Not necessarily. There are many factors that contribute to creating Surface Heating
heat. However, if all other factors are equal, the ultrasound energy of
higher-frequency transducers is absorbed more rapidly than that of
9
lower-frequency transducers, thereby causing reduced penetration. In
some cases, this may introduce increased heating near the skin surface.
Q. Now let’s talk about what all this means in practical terms. What is the
situation of most interest?
A. The situation of greatest interest involves the fetus with ossified bone
(second and third trimester) and a mother with a thin abdominal wall.
Because there would be little absorption of energy between the
transducer and the fetus, nearly all of the energy would be absorbed by
a fetal bone, if the beam is focused on or close to it.
Let’s look at the other two factors: transmit focal point and absorption.
A highly focused beam whose focal point is in the amniotic fluid will
Fixed-focus transducer not cause significant heating of the fluid, because its absorption
coefficient is low. If the focus is in tissue, all things being the same,
the temperature rise is a little higher. However, the same beam will
cause an even higher temperature rise time if it focuses on bone, which
has a much higher absorption coefficient. Be aware that there are
fixed-focused transducers whose focus we can’t change and multi-
element array transducers whose focus we can change.
Multi-element array
transducer
The other important determinant of local temperature rise is absorption
Line drawing 21-1 of ultrasound energy in tissue layers in front of the point of interest.
Increased absorption in these layers decreases the ultrasound energy
available at the point of interest. For example, an obstetrical
examination of a patient with a thick abdominal wall is less likely to
cause a significant temperature increase in the fetus than an
examination through a thin abdominal wall.
10
A. We have computer models that predict the relationship between
transducer focus and changes in the temperature curve.
Assumptions
• Speed of Sound Is Uniform Throughout
• Attenuation Is Uniform Throughout
• Absorption Is Uniform Throughout
• Absorption Equals Attenuation (Scattering is negligible)
Transducer
• 3.0 MHz
• 19 mm diameter
• 6 cm transmit focal length
• 100 mW output ultrasonic power
and color Doppler modes. Keep in mind, these models are for 0
0 2 4 6 8 10
educational purposes and may not reflect actual clinical situations. Range (cm)
1.0
We’ll see that the temperature increase exhibits a maximum at about 0.5
five centimeters.
0
0 2 4 6 8 10
Range (cm)
For the next scenario, all we’ll change is the focal point location. We
Homogeneous soft tissue
just saw the 6 cm focal length. Now, let’s see what the same model: axial temperature
transducer does in the same tissue with a 10 cm focal length. It increase profile for a transmit
flattens out quite a bit, doesn’t it? focal length of 6 and 10 cm
1.0 goes way up to about 1.3˚C at a range of about 2 cm. What does that
mean? It means that a significant increase in temperature near the
0.5
beam’s focus is more likely with shorter focal lengths because less
0
0 2 4 6 8 10
overall attenuation of the beam has occurred.
Range (cm)
Homogeneous soft tissue Now, let’s look at this in a situation similar to an obstetrical exam.
model: axial temperature
increase profiles for
transmit focal lengths of 2, 6, Layered Tissue Model: Obstetrical Scan
and 10 cm • Abdominal wall thickness = 1 cm
• Bladder fluid path = 5 cm
0.9
Temperature Increase (˚C)
0.6
Now here’s the axial temperature increase profile in the layered tissue
0.3
model for a longer focal length of 10 cm. The temperature rise at the
0 far side of the bladder is about 0.5˚C, a drop from when the ultrasound
0 2 4 6 8 10
Range (cm) beam was focused at that location.
Layered tissue model: axial
temperature increase profile Let’s look at a situation where the beam focuses in front of the far side
for transmit focal lengths of 6 of the bladder, at a 4 cm transmit focal length. The temperature rise at
and 10 cm.
the far side of the bladder is about 0.3˚C, also a drop from when the
ultrasound beam is focused at that location. Note that the increase in
Line drawing NEW 25-1
temperature in the abdominal wall is about 0.4˚C for all three focal
0.9
length conditions.
Temperature Increase (˚C)
0.6
That means if the transmit focus location occurs before the target, then
0.3 the temperature rise at the far side of the bladder, at a range of 6 cm
for this layered tissue model, is less than if the focus is at or beyond
0
0 2 4 6 8 10 the target, where the temperature elevation at the target is higher.
Range (cm)
12
Let’s see what happens when we focus near bone. For this model, 4
through which the beam passes, but our reflective surface is bone that 2
same output ultrasonic power of 100 mW. When the transmit focal 0
0 2 4 6 8 10
range is beyond the location of bone, focal range of 10 cm, there is a Range (cm)
peak in the temperature increase to about 1.9˚C at the bone location. Fetal bone model: axial
temperature increase
profile for a transmit focal
Here’s what happens with a transmit focal length of 6 cm, that is, the length of 10 cm
ultrasound beam is focused on the bone surface: a theoretical
temperature rise of about 4.2˚C. 4
dangerous? 1
0
0 2 4 6 8 10
A. Potentially dangerous. The examples we looked at are for educational Range (cm)
purposes and do not necessarily occur in clinical situations. For Fetal bone model: axial
example, the output power used for the calculation would not be temperature increase
commonly used, but it is within the capability of many systems. profile for transmit focal
lengths of 6 and 10 cm
Temperature rise during an actual examination depends on many Abdominal wall thickness,
factors. For example, very few patients have as thin an abdominal Focal length and location,
wall as we assumed in this model. In addition, the exposure to bone Exposure duration,
Bone attenuation,
Line drawing NEW 26-1
must be continuous over time for local temperatures to rise. That Tissue attenuation,
seldom happens in actual exams. Plus, some heating is lost due to the Bone absorption, and
cooling effect of local blood flow. To date, there is no evidence of any Tissue absorption
harm in humans from thermal effects at the output levels of current
ultrasonic devices.
The goal is to get an image that provides necessary diagnostic The goal is to get an image
information. If we are overly cautious, we may end up with poor that provides necessary
diagnostic information.
image quality or inadequate Doppler signals. For operators to
minimize the risk, we need to understand the factors that contribute to
temperature rise, for example, the thickness of the mother’s
abdominal wall, the beam focal length and location, exposure
duration, and the attenuation and absorption characteristics of tissue
and bone.
13
Chapter Three
Nonthermal Bioeffects
Issues Addressed:
• Onset of cavitation
• Peak compressional pressure
• Peak rarefactional pressure
• Stable cavitation and transient cavitation
• Microstreaming
• Nucleation site
• Threshold phenomenon
Cavitation was first discovered around the turn of the century, not in
tissues, but at the surface of a ship’s propellers. Researchers found that
the low-pressure region immediately behind a ship’s propellers caused
bubbles to be produced in the water. The collapsing bubbles damaged
the propellers. The bubbles collapsed violently, generating shock
waves that eroded the propeller blades.
Positive pressure = A sound wave has positive pressure and negative pressure. Positive
Compressional pressure pressure is also called compressional pressure; negative pressure is
Negative pressure =
also called rarefactional pressure. If the rarefactional pressure is
Rarefactional pressure sufficiently large, microbubbles may be produced, or existing
microbubbles may be enlarged.
14
Q. When does cavitation occur? p
pressure
c
Stable cavitation is associated with vibrating gaseous bodies. In stable Cavitation is related to the
cavitation a gaseous body remains stabilized and, because of the peak rarefactional pressure.
ultrasonic field, oscillates or pulsates. As the oscillations become
established, the liquid-like medium around the gas bubble begins to
flow or stream; we call this “microstreaming.” Microstreaming has
been shown to produce stress sufficient to disrupt cell membranes. Cavitation
1. Stable
During inertial cavitation, pre-existing bubbles or cavitation nuclei 2. Inertial (or Transient)
expand from the pressure of the ultrasonic field and then collapse in a
violent implosion. The whole process takes place in a very short time
span that is on the order of microseconds. The implosion can produce
huge local temperature rises that may be thousands of degrees Celsius,
and pressures equal to hundreds of atmospheres all in an area that is
less than one square micrometer. The implosion can damage cells and
tissue, ultimately leading to cell death. In addition, bubble implosion
can generate highly reactive chemical species. All of these effects,
microstreaming, implosion, and reactive chemicals occur in a very
small space around the bubble, affecting only a few cells.
Q. Is it really possible for cavitation to occur at the amplitudes and Oscillating bubble and
frequencies used for diagnostic ultrasound? microstreaming
15
A. Perhaps, if nuclei sites are available. There is ample theoretical and
some experimental evidence to support this conclusion, and that
biological alterations can occur. We are fortunate to have this evidence
because it documents the levels above which cavitation is thought to
occur, and because there is a lot of scientific evidence to suggest that
the onset of transient cavitation is a threshold phenomenon.
A. Yes. But since cavitation would probably affect only a single cell, or a
few cells, it is extremely difficult to detect an adverse biological effect,
unless the cavitation events were widespread among a large volume of
tissue.
16
Part Two
Prudent Use
17
18
Chapter Four
Benefits And Risks
Issues Addressed:
• Risks versus benefits
• Diagnostic ultrasound benefits
• Risk of not performing the study
• Prudent use
• New technology and applications
• High output, potentially greater risk
• High output, potentially greater diagnostic capability
• Shifting responsibility
Q. “Risks versus benefits.” What do we mean by that in terms of Risks vs. benefits
ultrasound?
A. The risks are the potential for adverse bioeffects caused by heating or
cavitation. Although there has not been a reported incident of serious
bioeffects on humans at diagnostic ultrasound levels, we do know that
heating of the tissue may occur and there may be the potential for
cavitation to occur.
Q. What are some examples of the benefits of diagnostic ultrasound? Examples of benefits from
diagnostic ultrasound: Cardiac
A. Let’s look at ultrasound in cardiac studies. The use of diagnostic studies
ultrasound for cardiac applications has increased dramatically over the
past ten years. From M-mode scans to transesophageal
echocardiography, ultrasound gives us the ability to image the
structure and function of the heart and great vessels in exquisite detail.
Ultrasound also has the ability to follow the normal and abnormal
course of blood flow within the heart.
19
Q. How about potential bioeffects with some of the new cardiac
applications?
A. Diagnostic ultrasound has an excellent safety record over the years that
it’s been used to study the heart. The nature of many cardiac
ultrasound techniques, the variety of imaging windows, and the fact
that the heart is filled with moving blood means that the duration of
the exposure of any one area of the heart is reduced.
It’s a real risk not to perform Newer applications of ultrasound through the esophagus and within
the study. the vascular space may result in bioeffects we’ve not previously
known about. We need more research before we can define all the
risks. But remember, the physician should weigh potential bioeffects
against the real risks of not doing the study and missing important
timely diagnostic information.
Example of benefits from A. Ultrasound has had a huge impact on the area of obstetrics. The use of
diagnostic ultrasound: ultrasound examinations during pregnancy has increased dramatically
Obstetrical exams since the 1970s. The use of ultrasound in obstetrics is a principal area
of concern for potential bioeffects. Ongoing studies may provide
accurate information related to potential effects of ultrasound on the
embryo–fetus. In fact, the combination of the increase in use and the
concern for safety led to the National Institutes of Health consensus
development conference in the early 1980s. The conference discussed
the use of diagnostic ultrasound in pregnancy. The committee did not
recommend routine ultrasound examinations during pregnancy, but
they did suggest a number of appropriate clinical indications for the
use of ultrasound imaging during pregnancy.
Balancing benefits and risks Q. How do you balance the benefits and risks?
Prudent use On the other hand, we have the risks: thermal and nonthermal
bioeffects. But there’s another risk that must be considered: the risk of
not doing the ultrasound exam and either not having the information or
having to get it in a less desirable or invasive way. As the American
Institute of Ultrasound in Medicine statement says, “. . . the benefits to
patients of the prudent use of diagnostic ultrasound outweigh the risks,
if any, that may be present.”
20
Q. What about the benefits of new ultrasound technology and New technology and
applications? applications
But it’s more than technology; it’s what that technology gives us; for Users assume more
instance, better quality images and more diagnostic information. Still, responsibility
all the operating modes and the varying output levels mean that more
responsibility must be assumed by the users.
A. We must learn to balance the risks and the benefits. We have learned
about bioeffects: thermal effects, or tissue heating; and mechanical
effects, such as cavitation. We learned how intensity, exposure time,
focal properties, and pressure are associated with the risk for
bioeffects. Using too much intensity can increase the risks, but using
too little intensity for the clinical situation can lead to poor images
and the loss of essential information.
Q. In the future, might there be increased risk as well as increased Future benefit vs. risk
benefit?
21
ultrasound devices, to the judgement of the users. In return for
potentially enhanced diagnostic capabilities, we will have to balance
the clinical need against the risk of an adverse bioeffect. We will need
a knowledge of the thermal and mechanical mechanisms, the
bioeffects of ultrasound, the ultrasound output levels being used, and
the relationship of output level to image quality.
22
Chapter Five
ALARA
Issues Addressed:
• The ALARA principle
• Controlling ultrasonic energy
• Controlling exposure time
• System capability and ALARA
• Operating mode and ALARA
• Transducer capability and ALARA
• System setup and ALARA
• Scanning technique and ALARA
A. We have a simple principle that we can apply to the use of ultrasound ALARA, or As Low As
energy. It’s called ALARA, which stands for “As Low As Reasonably Reasonably Achievable
Achievable.” Following the ALARA principle means that we keep
total ultrasound exposure as low as reasonably achievable, while
optimizing diagnostic information.
With new ultrasound equipment, the output display lets us determine Users control the total
the exposure level in terms of the potential for bioeffects. For exposure to the patient.
equipment that does not have an output display, we depend on
whatever output information, such as intensity, dB, or percentage of
power that the system provides.
Q. If output level depends on the patient and the clinical need, what What determines exposure
determines exposure time? time?
24
Part Three
Implementing ALARA
25
26
Chapter Six
Knobology
Issues Addressed:
• Basis of knobology
• Tradeoff between in situ intensity and image depth
• Operator controls and ALARA
• Prudent use
• Know the user’s guide
• An example of implementing ALARA
Q. How can the operator control ultrasound output? Operator controls and ALARA
A. There are several external system controls the operator can adjust to
improve the quality of the image and to minimize the output intensity.
To understand how these controls are related to ALARA, let’s divide
them into three broad categories: First, controls that directly affect
intensity. Second, controls that indirectly affect intensity. These are
controls such as Mode, Pulse Repetition Frequency and others. When
you change the setting for one of these controls, you may also be
changing the intensity. Third, controls that do not affect intensity. We
can think of the third category as “receiver controls.” These are
controls that affect the processing of ultrasonic echoes returned from
the body.
These aren’t “official” categories, but they help us understand how the
knobs affect ALARA. In fact, each equipment manufacturer provides
somewhat different sets of controls. By reviewing the user’s guide for
the equipment, we can determine the particular controls that perform
the functions described here.
Let’s look at controls that directly affect intensity. They are Controls directly affecting
application selection and output intensity. intensity
Application selection
Output intensity
27
Application selection With application selection, we may choose from applications such as
peripheral vessel, cardiac, ophthalmic, fetal imaging, and others. There
may be different “ranges” of intensity output based on these
applications. Selecting the right application range is the first thing you
can do. For example, cardiac intensity levels are not generally
recommended for performing a fetal scan. Some systems automatically
select the proper range for a particular application, while others require
a manual selection.
For equipment that does not have an output display, the maximum
intensity for each application is regulated by the FDA. The FDA
regulation is meant to limit ultrasonic output levels to ranges
historically used for each application. But users have some choice in
the matter; we are responsible for the proper selection of an
application range.
Output intensity or power Another control that has a direct effect on intensity is, of course,
output intensity. This control also may be called transmit, power, or
output. Once the appropriate application range has been selected, the
transmit intensity control increases or decreases the output intensity
within the range. Most equipment allows you to select intensity levels
less than maximum, say 25 or 50 percent. ALARA implies that you
select the lowest output intensity that is consistent with good image
quality.
System mode The choice of B-mode, M-mode, or Doppler, for example, determines
whether or not the ultrasound beam is stationary or in motion, which
greatly affects the energy absorbed by the tissue. If the beam is
moving, then each targeted tissue volume experiences the beam only
for a fraction of the time, except near the transducer for sector scans. If
the beam is stationary, then the period of time a targeted tissue volume
in the beam receives ultrasound is increased.
28
Q. What about the pulse repetition frequency—PRF?
A. The number of ultrasound pulses in one second is referred to as the Pulse repetition frequency
(PRF)
pulse repetition frequency. The higher the pulse repetition frequency,
the more output pulses per second, increasing the temporal average
intensity. There are several controls which have an effect on the pulse
repetition frequency. For example, with some diagnostic ultrasound
systems, if we decrease the focal range, then the system may
automatically increase the PRF.
Q. Next on the list is focusing. How would focusing affect intensity? Focusing depth
Q. Transducer choice is another factor that indirectly affects intensity. Transducer choice
How?
Q. We are calling the third category Receiver Controls. We use these to Receiver Controls that affect
improve image quality. They have no effect on output; they only the image only
Receiver gain
affect how the ultrasound echo is received and processed. The TGC
controls include gain, TGC, video dynamic range, and post Video dynamic range
processing. Let’s just look at one of these . . . system gain. How can Post processing
we use receiver gain to implement ALARA?
29
Always increase the receiver A. The receiver gain controls amplification of the return echo signal. To
gain first. obtain good diagnostic information, we need a high return signal
amplitude. This can be attained either by higher output, similar to
talking louder, or by higher receiver gain, similar to a hearing aid with
volume control. The need for gain is determined by tissue attenuation,
that is, how much of the ultrasound is lost as it passes to the reflective
surface and back to the transducer. In some cases, we control the
receiver gain by setting the gain control or TGC. But in other cases,
gain is automatically adjusted by the system when the user adjusts the
output control. If the equipment has a receiver gain control, and we are
searching for a weak signal, we should always increase the system’s
receiver gain first, then increase the power output. That way, we
reduce the output required and make it less likely to use high acoustic
intensities in the patient’s body tissue. Remember, a low receiver
gain may necessitate using a higher output, or result in suboptimal
image quality.
A. Imagine we are getting ready to do a liver scan. It will involve the use
of B-mode, color, and Doppler. Let’s see how we would follow the
ALARA principle to set up and conduct the exam.
Select transducer The first thing we need to do is select the appropriate transducer
Check output transmit frequency. Next, we adjust the output intensity (or power) transmit
setting setting. We check to make sure it is positioned at the lowest possible
Adjust focus
setting to produce an image. We adjust the focus to the area of interest,
Increase receiver gain
Adjust output transmit then increase the receiver gain to produce a uniform representation of
again the tissue. If we can obtain a good image by increasing the gain, we
can lower the output and continue to increase the gain. Only after
making these adjustments and if tissue penetration or echo amplitude
levels are inadequate should we increase the output to the next
higher level.
Minimize exposure time After we have achieved a good B-mode image, then we can use color
to localize the blood flow so we can position the Doppler sample
volume. This allows us to locate the vessel of interest faster and that
minimizes exposure time. Now that we have an image of the vessel,
we position the range gate (or sample volume gate) over the vessel.
Adjust output transmit setting Now we check the Doppler trace. We adjust the power setting by
again setting the Doppler transmit intensity at the lowest possible level to
produce a clear signal. We will make a few more adjustments, for
example, adjusting the velocity scale. Now we increase the receiver
gain to get a diagnostic signal. If maximum gain adjustments are
inadequate, then we raise the output to the next higher level.
30
That basically is how we implement ALARA. Select the right
transducer, start with a low output level, and obtain the best image
possible by using focusing, receiver gain, and other imaging controls.
If that is not adequate for diagnostic purposes, then increase the
output level.
Q. There are many different types of ultrasound systems with different Some systems do not have an
controls and displays. Does ALARA change from system to system? output control.
Different systems have
different controls and
A. ALARA remains the same. Keep ultrasound output “As Low As displays.
Reasonably Achievable.” How we do that will change somewhat from
system to system. For example, virtually all medical diagnostic
ultrasound equipment has some type of acoustic output control.
However, we may occasionally see a single purpose device that
doesn’t have an output adjustment. In this case, we practice ALARA
by minimizing exposure time.
If the machine has an output control, we use it and the other controls Acoustic output control:
to achieve ALARA. But remember, there are a variety of different percentage
types of intensity settings on ultrasound equipment, depending on the decibel (dB)
Direct unit
manufacturer’s design. For example, some equipment may have a (mW/cm2 or mW)
separate control on the keyboard or console that has discrete Thermal index
increments. Other equipment may have the intensity level adjustment Mechanical index
accessed through the system presets. And, output settings may be
displayed in a variety of different ways. For example, acoustic output
may be expressed as a percentage of total power, in decibels, in
intensity units of milliwatts per square centimeter, or in thermal or
mechanical indices.
32
Chapter Seven
The Output Display Standard
Issues addressed:
• Purpose of the Output Display Standard
• Mechanical Index (MI)
• Thermal Index (TI)
• Soft Tissue Thermal Index (TIS)
• Cranial Bone Thermal Index (TIC)
• Bone Thermal Index (TIB)
• When an Index is displayed
• What the Indices mean
• How to implement ALARA by using the Indices
A. One of many advances now being made in ultrasound equipment Standard for Real–Time
Display of Thermal and
technology is the introduction of output display indices that relate to Mechanical Acoustic
Output Indices on
the potential for ultrasound bioeffects. These indices are specified in a Diagnostic Ultrasound
Equipment
standard developed in a cooperative effort by the National Electrical
Manufacturers Association, the U.S. Food and Drug Administration,
the American Institute of Ultrasound in Medicine, and many other
medical and basic science societies.
Q. What is displayed?
A. Two types of indices may be displayed: a Thermal Index, or TI, which Output Display
provides an estimate of the temperature increase; and a Mechanical • Thermal Index (TI)
Index, or MI, which provides an indication of the potential of • Mechanical Index (MI)
nonthermal or mechanical bioeffects, such as cavitation.
A. The goal of the output display standard is to make users aware of the
actual output of their ultrasound equipment as it is being used. The TI
and MI provide real-time information about the potential for bioeffects
that can be used to help implement ALARA easily and efficiently. As
users, we can quickly learn how different control settings change the
indices. We implement ALARA by obtaining needed information while
keeping the indices, the potential for bioeffects, “as low as reasonably
achievable.”
33
MI is a relative indicator of Q. What is the Mechanical Index?
the potential for mechanical
effects
A. Scientific evidence suggests that mechanical, or nonthermal,
bioeffects, like cavitation, are a threshold phenomenon, occurring only
when a certain level of output is exceeded. However, the threshold
level varies, depending on the tissue. The potential for mechanical
effects is thought to increase as peak pressure increases, but to
decrease as the ultrasound frequency increases. The Mechanical Index
automatically accounts for both pressure and frequency. When
interpreting the Mechanical Index, remember that it is intended to
estimate the potential for mechanical bioeffects. The higher the index
reading, the larger the potential. However, neither MI = 1, nor any
other level, indicates that a bioeffect is actually occurring. We should
not be alarmed by the reading, but we should use it to implement the
ALARA principle.
Scanned
Mode
Unscanned
Mode
A. Actually, there are three Thermal Indices that are used for different
Soft TIS
TIS combinations of soft tissue and bone in the area to be examined. The
Small Aperture
Tissue at Surface
Large Aperture purpose of the Thermal Indices is to keep us aware of conditions that
Bone
at Focus
TIS
at Surface
TIB may lead to a temperature rise whether at the surface, within the
Bone tissues, or at the point where the ultrasound is focusing on bone. Each
TIC TIC
at Surface
Thermal Index estimates temperature rise under certain assumptions.
Three Thermal Indices The Soft Tissue Thermal Index, known as TIS, provides information
• Soft Tissue Thermal Index on temperature increase within soft homogeneous tissue. The Cranial
(TIS)
• Cranial Bone Thermal Index
Bone Thermal Index, called TIC, indicates temperature increase of
(TIC) bone at or near the surface, such as may occur during a cranial exam.
• Bone Thermal Index (TIB) The Bone Thermal Index, or TIB, provides information on temperature
increase of bone at or near the focus after the beam has passed through
soft tissue. For example, TIB is appropriate when focusing near fetal
bone during a second or third trimester exam.
TI is a relative indicator The Thermal Index is a relative indicator of temperature rise. Thus, a
of temperature increase TI reading of 2 represents a higher temperature rise than a TI reading
of 1. However, a TI of 1 should not be taken literally to mean an actual
increase in temperature of 1°C, nor should a TI of 2 be taken to mean
an increase of 2°C. The actual increase in temperature in the patient is
influenced by a number of factors such as tissue type, blood perfusion,
mode of operation, and exposure time. Those who developed the
standard deliberately chose the term “Index” to avoid a literal
association between the TI reading and actual temperature increase.
The TI does, however, provide important information to the user:
itindicates that the possibility for an increase in temperature exists, and
it provides a relative magnitude that can be used to implement
ALARA.
34
Q. How and when are the output indices displayed?
A. The output display must be located so as to be easily seen by the No display of any index value
operator during an exam. An output display is not required if the is required if the transducer
transducer and system are not capable of exceeding an MI or TI of 1. and system are not capable
However, if the transducer and system are capable of exceeding an MI of exceeding an MI or TI of 1
or TI of 1, then it must display values as low as 0.4 to help the user
implement ALARA.
The standard only requires that a single index be displayed at any one 1
0.8 2
time. For some modes and application presets the user may be able to 3
choose which index shall be displayed. For example, the Mechanical 0.6 4
Index will appear for B-mode imaging if no other mode is active. A 0.4 5
Thermal Index will be shown for all other modes, including modes
where B-mode imaging is combined with something else such as M-
mode, Doppler, or color flow imaging. The standard makes an
exception for transducers that have no B-mode imaging. In that case,
A display of an index value
the Mechanical Index must be available in the Doppler mode. as low as 0.4 is required if
the transducer and system
The Mechanical Index is required for B-mode imaging because the are capable of exceeding an
mechanical effects, such as cavitation, are more likely to be significant MI or TI of 1.
than thermal effects. Similarly the rationale for using a Thermal Index
in the other modes is that the potential for heating is the greater
concern.
A. The output display standard requires manufacturers to provide default Manufacturers are required to
settings on their equipment. These settings establish the output level provide default settings
that will be used automatically at power-up, entry of new patient
information, and a change from nonfetal to fetal application presets.
Once the exam is under way, the user should adjust the output level as Figure NEW Ch7-1
needed to achieve clinically adequate images while keeping the output
index as low as possible.
Q. Is it really that simple? All we need to know is the output index value?
A. Yes and no. A high index value does not always mean high risk, nor
does it mean that bioeffects are actually occurring. There may be
modifying factors which the index cannot take into account. But, high
readings should always be taken seriously. Attempts should be made
to reduce index values but not to the point that diagnostic quality is
reduced.
The indices do not take time into account. Exposure time is an Minimizing exposure time
important factor users must keep in mind, especially if the index is in a will help reduce risk
35
range that might be considered high. Exposure time is the ultrasound
exposure time at a particular tissue region. In all cases, minimizing
ultrasound exposure time will help reduce risk.
Q. Tell us in more detail how to use the output display to help implement
ALARA.
The second question to ask is, “Are there modifying factors that might
create either an artificially high or low reading?” These modifying
factors include the location of fluid or bone and blood flow. For
example, is there a low attenuation path so that the actual potential for
local heating is greater than the TI display? This could be caused by
an unusually long distance of amnioti, or other fluid through which
the ultrasound must travel. Another example is that a highly perfused
tissue area may have a lower temperature than indicated because
blood flow transports heat away from the tissue.
36
Third, even if the index value is low, we should ask, “Can I bring it
down?” Because there is uncertainty about how high is “too high,” we
should always be alert to ways to adjust the system to reduce the
indices. In many cases, an index reading can be reduced without
decreasing the quality of the image.
Q. Please give us some examples that show how the indices can be used
to implement ALARA.
Because there are three Thermal Indices, it is not so simple. As we go Implementation of ALARA
through the examples, remember the four questions we should ask by using the Indices
related to the Thermal Index:
• Which TI?
• Are there modifying factors?
• Can we reduce the index value?
• Can we reduce the exposure time?
The first example is a color flow scan of the portal vein of the liver.
TIS is the appropriate selection for nonobstetrical abdominal
examinations. Possible modifying factors include capillary perfusion
and body size. High perfusion in the imaged tissue will reduce thermal
effects while conversely, a lack of perfusion may increase them. With
increasing body size, extra tissue attenuation decreases mechanical and
thermal effects at the focus. Also, when considering the focus for a
soft tissue exam, remember that the potential for maximum heating
might occur at the surface, at the focal point, or somewhere in
between. For scanned modes, such as B-mode imaging and color
flow, and for sector transducers, the maximum heating is usually close
to the surface.
37
The second example is a pulsed Doppler cardiac exam. Again, TIS is
the appropriate thermal index. The cooling effect of cardiac blood
flow is a very important modifying factor. Actual increase in cardiac
temperature is almost certainly less than the TIS indicates.
The presence of fetal bone near the focal zone is the important factor.
If the pulsed Doppler is used to measure umbilical blood flow, and we
are sure there is no bone near the sample volume, the TIS is
appropriate. However, because the transducer may be moved, it is
usually best to make the more conservative choice and select TIB for
all second and third trimester exams. Of direct concern are the fetus’s
developing neural tissues, such as the brain and spinal cord, that may
be in a region of heated bone.
38
The final example is a neonatal cephalic exam. The choice of
Thermal Index depends on the location of bone. Generally, in an
exam through the fontanelle TIB is the appropriate index because of
the chance of focusing near the base of the skull. TIS might be
appropriate if the focal zone will always be above the base of the
skull. If the exam is through the temporal lobe, the temporal bone
near the surface makes the TIC the appropriate index.
39
Conclusion
In more than three decades of use, there has been no report of injury to
patients or to operators from medical ultrasound equipment. We in the
ultrasound community want to keep that level of safety.
40
INDEX