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Patient with AF should be assessed for risk of stroke and the need for thromboprophylaxis
o Analysis of risk of bleeding vs benefit of prevention of stroke
o Use CHA2DS2-VASc risk of stroke
Risks include: prior ischemic stroke, transient ischemic attacks,
or thromboembolic events, heart failure, left ventricular systolic
dysfunction, vascular disease, diabetes, hypertension, females,
and patients over 65 years.
Low risk do not require antithrombotic ; high risk
o HAS-BLED tool for bleeding risk prior to and during anticoagulation
o Oral anticoagulant offered to those who
confirmed diagnosis of atrial fibrillation
had, or are at high risk of recurrence of atrial fibrillation
structural heart disease, prolonged history of atrial
fibrillation (more than 12 months), a history of failed
attempts at cardioversion, and patients whom the risk of
stroke outweighs the risk of bleeding
Vit K antagonist ( warfarin)
Apixaban, dabigatran or rivaroxaban.
ACS