Dated ase emptying ty persist for ont
‘ce natn warplane
Yrs ee acts ofl
‘medical problems, facudng immunosappreson organ
Sjtaeto, and Inetons. Ate GVHD pat eon
tHatoccurnthe ft 10 dossier HSCT ison whee
"onic GVHD ir grat recon that ora ater dy 10
that induce uate dagen esi Ieee Gace
‘Skin manestatos may ile sto severe erythema
‘our ppl rath Liver aniston ay nee dct
Ahage wth cholestatic ivertet sherman, The tet.
fn Be affected anyhere fom the mou othe ana Gk
Inclodesthewbeafone or more mmanesuppesvandat
toplist pets monalonal antody ibod mn
Nutrition Therapy
lems lated 10 metalic Gangs sche ancer cache,
{nd w ede interventions teat he dense aie
ance deh" Oral nrton iterations ae elect st
Increasing mateo nae and ipoving ve anes of
tly of fen patents wih cance wh se mantra
{ky Nation therapy has Ben ls ete in improving
tiontheap incane teste mut ale be weg pte
is posse stimulation tumor powth and metas”
Nutritional implications
Cini titans need to be svar of thine cance diagnoses
{nd eaten that ae only eure ti Te
Aca: Malnatiton Is more prevent the wh hare
bee sik for longer erode fe, ad ie etme
ied and net and ovarian cance Coe sea pa
lems ar aus vomiting ely satya ahs
ltgu. Nation problems tnd with head a neck can
cectao due phapis nd odynophapa Aol hes se
tects have the potential to pace nda nto
on In adn patos may eck ot Complemeary ad
Atherativemedline (CAN) therapies Chap 1) wot
‘thot inering tire ce prover Some tapes
tay be ttn adequate wih omental
Nutrition Assessment
“The Paes Generited. Subjective Global Assessment
(QHUSY have wn ad to sceen ener potent for nt
‘inal rk The Scored PG-SGA hasbeen show be
‘ecurt at distinguishing wel-nouchted patents om mal
Nateion seamen methods ate cand a Chapter 3nd
lene for asing cache ae fared in Cpe 22,
Batt shouldbe calcd isthe Saved PGS Ide
the following weight and weight charges infomation
inthe constipation, sbi ui ery ety, mows
tals bit wo chews and condition o the teh gums nd
‘Simpertnt to determine wht Kind scene le.
Nutrition Diagnosis
eds nae Ol nts neque ald
intake Ganction realowingo ting chev
‘Sty niente npn eer
fer patent wath pated srry ek hoy a
{spent or pected food-melation intercon pec
Nutrition Intervention
Interventions for Common Side Elects
‘of Cancer and Treatment
Nowa and Voting The rt comon case of mes ad
‘omiting in cance tnt chemother thd
‘sehr ln tes an emting (IN) Noses
{nl woratng hive mulfctoaleloges ee Cape 18)
The most emetogent chtherspenr nents nae ee
st, meats oso neyo fs
‘hble237) Newer ad voning ec wih chem
{oy eas be aida scat dele eran ee
Attu al von ocr with 9 eure itn
sf chemotherapy Deed rae an vor use beg
2 hour ar the het bas ben aes ad
mays upto a week: Delayed mene ving are ast
en hates enn atin aoe
{nd vomting mort eommanly ear ble the natn of
‘erates. But a abo scr ig ear ilatn
Thistypeof psa and vom fn fem ne
even andr pry contd es and ontingsgt
rcheapy 03
Incade groing older tbseco ue expomae to ang
Imones fray sory of ance leak ons, poor
ato dese (6VN0)—»
‘omophage por satoney
Cancer GeneticsFigure 23.1 2014 Estimated US. Cancer Cases and Deaths
ora iraopase —/—
=" ae
Noten —
—an i
“There are wo mor ype of ges that e thought to
Infience the development fence oncogenes and amor
sep gne hs hop thoes
‘pressor gnts ermal ancl eth (spoptoi) b t
"rts orm they ma le ths ition, net pane,
“also the capcty to prolate at they diferente nd
‘ete enconal apt Norma claves mumber af
‘entra mecanisne to reer guint genet seats
the fat (2) phe of the call vision el, wich ep
Inte by merous mechs a pnts tel prepares
te replte he genetic materi end check for muons
Sh adequate resurface figure 212 nating the tee
‘eye chelate inated nse In the § phase the
DNA i ropes, A the en oS pase secon chek
pevlrmed toconkem hat the chommsomes wee dpsed
‘erect theyre the cl roca tp Co In phase
{Gy the cell prepare or vio by syrthering mite
spindle nate rte need to produ two cel
aera | ate
=
ey
Ly
\ | nei
‘ny polo damage sere cll progression sop and
(ca dnt to prevent plain of damaged cll Cancer
through oncogene andlor mutated tuner peso goes
‘lei uncool roth besa of sora ells
‘heckpoint,inadegate DNA rea in fare oper
“Changs inthe cll cycle atocited with cancer may
also rel trom aberrant pene exrsion,Epigenetie !
the ty of changes in gene acy tat ae ot cnaed
by changes i the DNA sequence Caromatin she com
Pee of DNA and. proteins primal histones—in the
cou of cll (et Figure 283) On function of hr
‘Changes ingen expression can rer om aeration in
ts dinaleotdes apd modifston ose by ce
nor methylation Hyperetyaion of rmeter ronsTle 23.1 Canc Preantion Guidlines
Rens indie Cs
and mani sey wiht ought He
* ft gon tale aC to we enc
Seisetaptonp aris
yy active
Line str tr hat og don. sg
ashe det wth an epson plat od
yo ink salty,
“Entrar ncn pe vonn ory
AC Aecommandatons or Communty cn
ube prhat an commanty renin sould work
‘Sh rn ies ery
cll art Heras nutrients aed in ethan
‘ch a fle cd cn alter gene expo tthe transsp
onal lee epigenetice has great portance wih te
fai of watson
Other altered gene expression promoter inde ho
tones shat androge Tike to rote ete ad
‘srogen linked fo best td endometrial cancer. Chem
"any: Compound meetin chemoprevetn ies hae
Table 23. Signs and Sto of aner
etre Wao ons
tue
fg may bm pra sya of rc ay ape ty
rerte nex amples sada cnc Area
Stn changer
Figure 23.2 Regulation ofthe Mitotic Cell CycleFigure 33 DNA and Otromatin Structure
Cancer and Nutrition
methods such
‘eecontal tie and timing and
sbi promote the
m renting hot vel
a se
‘conor
amnion ee Cpe 2
Medical Diagnosis
‘Semic ans eos sr une and other
‘Shae tumor BomarTable 23. Tumor Mika ferSlcted Cana
‘ava ec yet
Ar mun ee rss is lal Pcp ps
Yeas mastonwayas Colca ama aig aer arte wah estan en sae
= eet
ae ge ey Seat ao ene
oe save Blt ce! weer ate et wane
‘or rescton and asst ofthe anatomical sen ofthe Figure 234 Needle Biopsy Proce
Geese. Tuer imaging ncn ac vale fo it
ng techniques inde agate resonance nang MR,
ination thats chal ust neering he ase fe
‘hacer: the etn oes inthe body tnd the umes
poten a eer Calling ts iomaton compass the
“hich pro technique sed depends on nmber of
cor ing te pens peeing 2
seatnen when dion tad, bloc carat
ble in the communi and Insurance approval of diagnostic
foo ep ae ae lcci he ered or
‘eociel Sance a ancora ae he ded mt suc: 0 3018 Grons nin,Table 23.4 names of elec Cances
+a ng rn i cur
uc ers nen)
“heen a ecco
neste aac pas! See TR Z34
‘Sremuml canr peed ares
The tayo then ad ad aigned “age” on
tebe fel tp te of ng, wheter sens
‘lignan darn of eifeentitog, aan Se an fan
{onthe NM Comite ofthe mention Union Ags
Cancer nt he Ameren Jolt Commit on Cancer hae
freed on the Temor Node Metastases CENM) Staging
Sater peste inBox 7 (1 = depth of tumor mason
‘xtra renal enh node M = alee or pres
‘Eten metantaes) Staging of tos le to ais
tester planning ovdes prognostic nfemation, ast
intrentment auto, and belp to day nda ag
tay be ig fr clic wae
‘Treatment
A patient may undergo one oF more ote ftlwrng te
nets depending onthe cancer gros surge edition
thepy chemaberpy induding hormonal therpy and
oeelatageted erp abnor Craig
tmuncteray and one therapy very cancer eaten
imtoxicy bec they have a mal rape ides the
fege of separation between tne ant therpete on,
‘sinfued ino te body crsliton ll clothe bay
toe expned fo the tne eet ofthe dra and neta
‘Tumor Node Metastases (TNM) Staging System
Sea eo doen
nay re ter agra per
Spear haaicay
(Grn tu The ror
ety sates earth urbe,
Sem reny on Mane
‘cain ety gh re
+ tx rn te ty yh nese
+ Noe ty moh oe co nt
entero
ten yey os
‘tape cape
woh a oe
‘torent ay es Pabody systems wl be aed. Chemotherapy aft ply
aking cai ence, the rp dividing ane!
‘cl le signfcayafected by mort ehemotherspetic
‘unt This rome rensn mos patents undergoing chem
robles daring ter cours of teat Because ae
ters contain opi viding cll slope hi as)
Isao a common side eect of chemotherapy heeft
rg atnent nd ration therapy depend on hep
tear dagnoss
Thetype arsine peri dopens on umber of
‘str acaing ton the tray sof he amon
‘he eath the ina In eral lage ty ans ae
rot cule with dregs. Drape ayo Be let penetrate
into asa amor nace atic ol he cl Aly
tote uly toe map not beeping the ine
eet and ths suet esis he aor a.
Theloner atmos hsbc pent the renter toed
thatthe etactaed eign ieee dg
‘herpy Understanding the eatin peer ane
The ent aod fpr of tetent pln wl dterne the
pel eee efecto the patie tions at
surgery
Serger nda cancr prevention: goss aging re
met (rbot caland and metastatic das) plist nt
‘ebb Sergey may be performed an nial has
Shinceased ik oer eg a arial bet ence, The
ethos obtain seo Serine wht th sor
‘benign cr malgant depends onthe ype fants bon
Collected malignant ne ples can apolar
‘Sonen he tumors ptr of growth dogs fe sb
Srgrytconsdered theron ode of et
{the cancer har ey tetas removing the aoe
(aebutking may mp quay fe an permit aint
therapy ome more ceive For expe emoving ue
‘king the exphag wed alow the patent tat ne
‘ally Palate surgery ase otis dee andlor
treatment elated ype witht tempting to cae the
‘ord comprssion ea expla pli therapy
Advances in gry fave slowed ran reds
‘ter eonery. Peer hgh nde aye fo teri
‘cer cals pad) ae ing somone than te pt
{nd pone nly theft ring Ip ode» prea
ing taor woud encounter removed Chemotherapy 2
‘aaton olen emploted blr gil econ In rer
‘Sai hin mig nae Reni
Cancer Diagnoses Requiring Surgery Thi scion
ees the mae cmon doses teste with geal
Poudre that ipect on mtn nae gestion, sn
Sgucat aang tem nti side fects occur
‘ost ten with cancer surgere nveving the head ec,
tnd omsch (partial nd ttl prety Stil proce:
tires may potently aera duals sya appen.
{nce (mastectomy) ake oat anton (ony) orth
(rea neck daecton), which an contate to depeson
‘nd vst in edued fod inte and weight los. Suga
treatment that invtes sina ofthe Homach or all
Intestino enoval ete eopagu or ong il hve he
Cancers of the Head and Neck Sagry tht inves
the eal and neck sre may el ny felt chew
sel and day vith speaking nado, patent ih
Ind and nck cancers pil hve Nr of
tance andlor substance bas and sigan weight ost
fon is etiated ht 6 of tet th ea ad nck
ances il preset eth maluton she ine a dino
$0 Sua procedres rhe ad neck cancerscan sg
ante both appearance and ncn. depending the
‘rp and econo prods ened son
We the pry surgery the pet may eo under aph
‘emo of all mph nodes on So side ofthe mek with
Preservation of the spl scoemary eve, itera alt
‘ein andlorsernocldomac msc Sete nec
{clones oct mond oon or more ph ode
National Comprehensive Cancer Network (NCCN) guide
nes vecmimend mentoring of ton ae for weight
los restr tan 108 a el by weigh anor icy
swallowing peta treatment”
Esophageal Cancer Exopagelcancer itll uncon
‘nonin the United Sates However the progenies
‘ot patent preset Rik fae for expe ance
td Bares ctphag econo eine by get
‘strosophogel eh dae ee Chapter 1) =
treatment or esophageal ance Many pans with eso
fealcacedeveey ccs some yttinthe prngrecion
tthe dacse" Trane hat and ane torce ephapse
tony file controvesi aete mnt oon reer
sch rue for recom the sop I the de
‘be esophagus canbe reconsited frm pat he sal
lrg insti Suri procedures for esophageal ea
tents requ placement oa oding tbe ding
Sastre Cancer Ath not a coramon in the Und
‘Ste gst cance rman te fit non common cao
try fee Chapter 1) the only petal curve
therapy forte etn of gat caeneIntestinal Cancers Cancers ofthe small nstine ae rea
anv sipficant eects on the sbieyt digs and absorb
‘on the amount of smal bowel hat is resected the ability of
{he emating pton to nop and wheter the Heel
‘ve could be spre dig dhe srgery See Chape 15 or
“onal inormaion.
‘Cobra cans talib thin mot ominan cane:
concer othe enon and sect te etd pal ith
Sarr and come, Sarees perfor for elrec
See Chope sor dato norton
Pancreatic Cancer Pence ance the fourth lending
‘hcl cence elated eth or bath en a ee,
‘ope rh of al cance ranted eats: Benue pa
‘Creu cancer cn selon ago when ttl oe
ited and mal eset ad eect seme thepes
tc loking te Ices ees evita he sane the
mot tee" Purest eancer Geen dlagaosed
Ute tothe vague and non spel ymptoms tha aco
tan the esse ever wow an anaes recon
{Rim aburcton ofthe panera dct oman esas in
labora nd steatonres, Mls tents with pane
tance ao have byperseemi.
epecioy alo kun athe Whipple proce. Hixon
aly the suey involved temoval the pancteatc head
‘luca allan sd le dct with o without the
{ue anu Amor wet modem ths prose
Frese th paca otc ant
‘atc surgery, patent shouldbe towed anormal ee
iat rection Intake sl be erased a oletted
Ter t-t dine. Tike feng shoud be administered only
Crepes nications and pastel nation sould not
[temple rutin The to mos common port Bel
Pots ow ths pocodare the acon jean
supplements se reommended based on theca 9g
{eh ofeuorchen and eight lane” See Chapters. 15
{dT for aoa! ifration on naeton diagnos nd
Chemotherapy
Chemotherapy Isa stem teste ad ier from a
{ro alton nt sec he whole body Over 100
‘Xcmotherapy dap are sel olay carlo o eo
trate the cave, Re soe and pean alle
Stee the symptoms Tey can alo be gen a a avant
eine ean ete by radiation orsrpery™
Chemotherapy gts cane rope it four bod ct
ove thse hat ast DNA fargrepeatos 2) sal
‘Mineo ological (ah a node or crn)
Cloned ancl deeloped to nerat wah» me at
(8) ormonal therapies for aberrant cellar behav, ch a
Src eget char etolines or anebodes hat ete
‘Jot of tumor elie dae how inane eons oi
Ideal, chemotherapy twatmet shoul il he cancer
{nos cancer drugs have 4 elatiey narrow therapetic nde,
{O'lower doves are mecca flv. Chemotherapy
‘gens cm be spect lao cet DNA mods
‘erase inhibitors), indirect DNA ages (antimetabolites and
Stumm target ger etn rected
mom of he normal cl the body ena reting ap
they are ore poate ror he eal efecto most
dyer ar scope tthe fect thse hal agents
tole the tat Ande legen sch a the cel af be
‘one mato (ed lod cl, wht Dood cl, and plate
Tey, the epi Uing of the geiestinl oc nd
the ha lies The mow comnon se est, herelr
tte dct tony to the cll apd lode netopen
thrombocytopenia dah, macs (seus
Ite nt hap) and alopecia” Some corterapete
‘eet ae ale font sate crt, euro
ea neprotnety Table 225 atthe common de eet
Radiation
od sar tse seman tyres rca
aed cance the hea and nes, ad ances of Oe
‘viens tumarcamarberoned spa oc wheal
feral asta present orton be eb propia
{o preven lela nts ofthe ano palo
Te dled with ectromagnte ye (a
de) and charged pitiless) aod de
ca al by tring clr and wader materi
hy DNA he mt afl oe aration a
She fonting nation ras he strands ofthe DNA
‘sing to et) eae Raton danmge sugested
‘yp and cal na hpontette les 1ceah
Withchamotherpy tae celta contin rl
Aisa ets thse nde ephelal cals Doe
felts mph ts snd ai els at ane hed
fou ec tony of RT i lad to thee
Imodited. Toy may be exacerbated whenceTable 235 Choterpy Agen ade ets
‘in btn tesa
‘Scare, heute oan,
‘nepaanouta
‘Ppsomase tite cn
‘The goal of texment planning isto unr eadite
Ing ocmal tes Neca cela wall the
oa cls ae scape to the fai af thee,
‘asormmade lead backs te developed bor ch pn
etc alain that yb inthe RT idan at ns
be dag doring RET maybe amined eater
inurl ete ane oi combination eral bor
{tether administra y incr nclert os ay
Sassi an uta sing) uly Say pore fa
eid of tine appomatty 6 mc) depending othe
"anor beng rete Brachytherapy ime the eens
lacie sores ether with a cing et
(tthe vagina n close roi tthe tao econ
Inusatty bachrbeapy sedan cancer otter
‘ate and cers pany aderans nd aan nes
Intros brachytherapy my be ed to wet ep
‘acarinoma river metstsesRadaton ane ci
‘othe tat tse via rinucdes Fareunge ean
atu take wp by the dhyrald Rademunrherapy et
the dene ation to petite toh tector,
‘22 monoclonal antibody (MAB) ooh Pasney.
‘ai therapy igh dered by ser) res cance coe
aes sce ym OU oe
es esi te Atay eda
ren ut tat ia ar hen 26
‘gsc son
See iy arse
Radlaon therapy is conmonly administered slong with
I maybe piven rr faving (ose per)oe Sarg
when is wed t combi wih sumer, apecal
maybe administered price wo ncoahranh, daring aoe
oma fllowing RE (nntenanee) = RT may Sse
sed conto incr sing fo meat ds
inorder top alte pain, Whle- ban BT fn means
lease is ot ed with th intention of eatng eds
butter to conta symptr suchas hah nde
problems Paliaive herpy fen dlncred at igh ose
for shorter periods fine A senda cet yn aaa
faceted raclonation which te oer tino
‘dinistation ie reduces however te mune o factor,
sorta dose othe radon tnt ceed aoe
ination isan estate nd secede a hosp
forbend and neck concer Toes nm Beeatee oe,
‘alan thon rcringcomamitantchemotiony
Common averse eects Rots head a ec ara
include tig, muon dpgeune, nevatomis seed
a tosalvary hand destruct dyophagia, otproohogy
tnd severe esophagitis. Sp al mnt by soenar
‘ately day 10 of HT and coon untlsbont 23 ete
see RT hasended, Macon zerostoml and oyophagis
ue to esophags maybe tert nd ditt cee
eet 22 etwarrants emporary iacomtnuntion of KI The inal
[Bac high if aeyation det adeqate eid nae
snd may awed tenuis for ydetion and lect
ine eovecton, Esophageal ss may become exten)
{Tadd able tothe cee tat rl nae Is mpos
Sle sup placed fing tbe may be dete to
Feeding tues may be contndeated de to the Fogle
tutu he esophopssndlorebtuction ofthe sophags
TT whe sbomial nd plc a can rena rad
thonenterin aevere often debating dese at an ake
ple year A toast” Symposia severe
‘ares and malabsorption, Media therapies ae primary
Sportive, Bowel inure tha esi nfl, scr
uP Shtoic libenepton are poentaly fe deaening
Cmplestions aba sgt impacton ay oe
Biological and Targeted Therapy
og therapies Table 23.6) my be wed eat the
anc ive he see fects father cance eaten
Seen bleed thot the nmane sytem natura capac
Toft dtc nd ety sboroalel prevent the dere
teed detection by sing ae OF mote stg. Some
Doge therapies fr cancer ae vases or bteria to
fells These types of Wola therapy, which re sometimes
‘ele fo calestvely st lnmanoterapy” or weal
‘ponse modes da nat rt cancer eli die
‘ihe ileal herp, sah as antibodies eget
fence aaa (OA DNA), get anc cls ety.
Frog thersps tat intertvewth spece molecules
Inobed in tamer owt sd progression ar ab ferred
teased raps”
Immunotherapy Monoconal anodes (MADS) are
labor precedes cht ind Yo specie at
feo expened by ater calls MAbs silat a nae
Ropons thet deste cancer cl in seserl way ncllng
‘ing the fenton oft es, garg apopton,
[ahbinglgaltht revert nsmane cele atch he
tyson toes edi canc nding with
the devpment of tmor ood wads by wreting pees
that are near or tno growth bing teal uice
(gow fcr rcpt and peventingthe rgd cers
Cytokines Cytokine ae signlngpretentht are proce
‘ote Blot xls an np mde and ete mene
Feepnssfarnton, and hematite bod cl
Teruton. Two per fine ae aro ret patie
teh canteens (NF) aed ek 1). hd
‘ype enatopatic owt facts. ae sed to counteract
‘me ofthe ie ef of erin chernotarpy ronan
INF mayabotahisthe pth afeaner allo prom
i death as ben spe or he stent of mele
‘soma apn soma ad sever hematlog eaees
Ticmatooit: grwth for ae 3 spec das of
aly oesurng etki Al Dod cells ase from
ematopolet stem clin the bane marom Baca che:
Irotesyy age lrg prlraing cl, nclng no
tml blood stom cell chemathengy depts thee stern
els andthe ood as a the produce: this rol
nei, detested ating abit nd lower white
‘icons tt make chemotherpy patients vaneble
nections Seve! Rematopoleic powth for ave Bek
opened or lal ne Eeropoitin simules
Bind el formation and IL-l erases pact produc
tin, Gramlneytemacrophage clon sulting lacer
[G-CSF and panne colony-nulating eto CSF)
Seth merase the mambo of wht od celled he
Fao necons G-CSF and GMCS can ao enhance he
Immune syste pci ncn response by nce
the mmber af xoce-fightingT cell GMCCS apd CSE
‘ee wed i combination wah eter boll terse ta
‘Meta loge tery cc Bone pi tus, ee
hoe th te ofnecton and ike symp
‘Gause voring chile ve ndanores)
Hematopoietic stm Cl Waniplntaton Hews
see epson SCT ete opm
‘ree ahemnaage ants ns teog
‘Rel oe prem th ney peel
et scrns parce ee hen
sprites edn eet
eno and pon cane oan ao ke
Soalne punch ran core on go or
yates torn fe rer cia
Ione cl ned wre cone
Sa Sem HSCT mabe buted fom oe
ase) er leo sad) et
oy crs rte ne tl
eS enema red sap
fcr edo spn ite
set tn alr rls ses SCE
anu andepong nso RSC ht
cence tabla ed wy ad no
seeeceti ated tl
he tm ceeds np
sn a il bya pc dope
Pineal ce te eed Arar pore ig
Rc dees hts ery se
Sa iraaton aoc smd he ei
teeorconcing pienso ened oe
dusts copie consnng ee
‘Sheree npn poe ue rine
Fronts btn on a sl eget of
Sc td ome mt oe Nae
GcTacthated wih th ena 8
ic ny ao exp nici et
ton tno gett hot ne HD
inca cpl eed ne
ac Cvt sya inte nade rei
Monet HSC Newer de hese! soa)
Table 23.6 Biogas harp Agents
Tet oe hear ta
some Sagi ope cet SE
Sand vrncion yen ations rat ree Gene
aan nea a acer nx?
row aa apr non
stone deaayeses OOACS er Zl,
ec apogee aa ant rom ato EG hie
“age ttm toes
Dorey sn
+ Moron sin DAE rd at
okies soon 16 i
‘Theepybitaen pang he 12 BS Ans ony se
cela be contami wth tamer cell which oud ed
oom setts
{etter art an grt om aes
esp oun een de, tn Na
anes MX etn ae non dy
oe pg oe eget es
‘irae wher kr eet
withthe high dose of ehemethengy land 180) oausen
oting, mucositis dates, aneeopent eligi
pel) levees and ineeonrtypily dewey ed.
ily aftr the condoning regimens dese Severo
“heer dopends on the tena ape of grt wed
Late complications are mo commonly abered after
am alogene HSC, and cur as conan ote
otng ten damage orl se, ae om the so
‘GVHD Long term sompiestoninclad owt eration,
Intron fle, rae ont mero eter
‘fects nerocoate defend econdary mignonone mato transplant
CD ich cu i a Wah pn of se
sical problems, including. Immunosuppresson, ongan
‘stunctin, ad nfetione. Ate GVHD tal reject
{fatorernthe st 10 dyer HSCT ffson. whereas
{hon GVHD i rf jection tocar ater day 100.
{GVIED is thought te be mented Wy donor yphocytes
Shot indace ote drag nthe sh ver alor Gat
Skin manflesatne may inde sido Severe een
toon paar rah Liver anfettons may nde uct
‘mage wth cette eres sboormaiies. The Lact
ane afected anys om the moth ote aus.
‘unestatone sane rm dy oath and ofl weratons
ta i mon! ge ns Se
‘opie sens mamta ant, bois ie
Nutrition Therapy
Jems related to metabolic chang, such as cancer cachexia,
tin and eight lo have lng been known to conte to
Nutrition Assessment
the PaiensGenrsted Subjective Glo Asiesnet
{@G-5GA) andthe Manus Unive Sreing Too
tecurtatdtingishingwe-noursbed patent res a
toured alent and high entity and spect
‘Nurion sessment methods are coveted in Chap 3a
Eatin for auessng caches ae fvared a Chae 22,
Bin thu shuld colsed the Soved SGA cade
the flowing web and wet hanes norman: i
Atcha Constipation bora sin ear ste, mou
‘ove monte changes, or dpogni
tay ality to chews and coin of teeth uns aad
ingus Avevow ofan inva mostecet tary inake
tan to determine what Kindo ode can ete
ied and wha any peal ise abe on ading
Inet or tina epee
Nutrition Diagnosis
Nutiion diagnoses sociated with malpancy wil ay
stlerly dependent onthe prarytmor sie exe
ot buen and treatments modal Pose ngs
Include lua weigh os nan eer) and prec
Take aheredGlfanction swallowing and/or biting chewTable 237 Rte Emetogei Potent
aninepasi ag.
HenIOR) cone ant
jepheema 1500 m7
aon Pas
arn Dana)
Petree
encores
or ced
Tsuna een
ing the fi chemetay seton and more cron
sen pel pets Deed ti mening an
edoymptoms feat tay Hao mporaat
onthe ld being Almost 100% patents sender
‘Mapua KT casa etn ann and voting staring
Santa anaes a orn yl in itn
inga patents nuttinaiile Patents ten presrbed
TEthold e aen teat 30-43 mites bef els
‘vad evn patie oo fel nant a the tine
since ths manages both eed and atpatory CIN
SeeTabe Tait in Chater Iv fe a Ist of meditons
drproned to at nase and voting, Marana i
‘Naac fro cooing dor canbe tian by ing,
ings walk when mel ae bing cooked nd avidin fy
ingot oo which emits moe odors than most ther ems
cooking, Patents shoul an ends and ly members
to odd prunes when hey ae wating See TB Tain
{Chapter 1 for addon! ps A carmon ese of aa
seeing he lc ml rn
"hater thre pnts eae wth chon use.
Recommended titan therapy for east et 2
al fw armel he orig ofthe fie este an 9
‘Noi ie, rs an ort oo for eer dns 00%
ie the eaten A de gud dt forthe ft hours
‘Salina, consumpsonaf lect fotedbeverags
dnd nom acl rat di apple td grape jie nears)
‘ould be encouroped ic hpertan ents to 0d
[vce at ny tthe cance foremens i igh ice
‘once favorite ao har been vite the Helo of
‘rcqoet consump low. The same prince apples
{Othe wae of"eay” gd ntitna rink A pte
‘thos vomited monal beverage il sce vr
prcubly coed by thee Prokinetcr may ab be
rset omiinineomtng
‘No pharmacist methods hat hve been
sed th aig ster to provet oe et apes nd
Pants byposs, and gaded mage ee Box 232}, The
tol Concern poles eucaton materia
On dhtary suggetons fade ees fear ant etmek
{wmeacergovtanertgnaopiapetingunts) a wl 05
Early Stety A commen comping exposed by cancer
penis ie rt cate at mach aed Tg ll
hae start eating” Ts desc the spo feyProxsz cmcaamucanons
Botanical/Herbal Products and Nutritional Supplements Used by Cancer Patients
Spm cdc
te cy, V_—T
en egy ve Cerny Myttere
settemy otectee ap, en rm
yt se
Noun nse
ety which s case rma by delayed ga mpg.
onan stents ee Figte 23.5) sd sald Be eonaned
between mens rathr than eth ma so ma 0d
{cig of nem. Cnsmpaon low ep cho
fal" Metolopaide fr ramps nal see
ih ate thea sey Aorta ec of
tents that are aledy afr denen EFFigure 225 An Appeting and Nutent Dense Smoothie
“nfectea bythe many ges that ner
Studs nro weanincie
suse ight nay cous you may ne
ins the man vue of cane tetmet-rdated pa,
Shh fs frm 40% to 70 af patent receg chemo.
They orrditherapy bar been ropses hat macont
‘ana dean recteyotoncty lol sue caine
‘Chemotherapy induced macotis commonly cu
5-7 day alter chemothepy tated and ay eomtioue
(free tthe adi) Spnpoms vl cade pan and
thing wth chewing and swallowing Maco may Be
Severe tomgh to cue the ptt to complet fr ny
odor fanly which can lead to depuration abd sa
‘rei ose Good era yee is ipcrtant fr he ptt
“ioral contin order to pete infection. Box 23
‘itn the NS recommen or eventing sd et
tine sopplementation daring radiation therapy to help et
pane mac
herpes Inclading nets such a fe, yt an
ten and soe no cy lc
(pa vcore re ctl
1 Uelgtain years bcome
remasterted atton dant pre guns reneged
the mucositis ese. The pent fold be nursed
‘ately sat oe n scots otfals al
be ded shy can bathe macs, Liga sto
eta to pee ees no-cc ke ss
‘ects may be all High sere high poten
‘Sates or musionalSpplements maybe bree ss
time ce Te 25,
Dahon Antincopttc gets get hoc thi ne «
igh repletion xe inading he nthe at eulng
Ie fey §-Aemourscl tbe nap erat
The pate with dares shold be encourage to dink
sal ano of i eit roa a age
an excite dates, Char hglénutstonalbeerges
shouldbe encouraged se stare ection ange
sexbed by herp. ntti the patient enero
Fis ore intake foo gh slble oer may help
the tater of ares weve fen thee pte are
2 por ape and may hv dca tine ices
ina of foods i snr (arth deas on ats
Table 23.8 High Koco Hh ron Nutenl Beveages
Drenthe ey acing ae
‘be relied to anther pics matical pois ean
‘ects changes even befor sags ade ge
pesto scion ody ving by inproving endurance
Table 23.8 tston herp he ett of ea
“haem ep ore ae
‘ie re agents hve Ben eos afl er pete
‘Mimlaon’ meget sceate an conrad agen
{Ser Tible 113 in Chaper 1h) Catster shuld be
Interventions during Chemotherapy and Ration
Sreatmant Specs sutton suport
oxprenra shoul ot be wed rotny a an aint
Sudan or chematerapy ain spp in patients
‘and who are atipated to be unable ingest andor absor>
‘Megat nutrets oa pong prof of tine” Pants
hater change to ele he nto ested dele
hatin ocurred shold eid oon
Noe the loc tan ehanger in Soy weigh dng,
treatment ae oe 2 fra dco freon concer
torch undergoing cemtherap leer er
DE
Childhood Leukemia
Colette LaSalle, PhO, RD san ose State University
Inorwng eter rae ype eters AL)
pce auton to et dy competion ek
Sh ayn a re
‘on he inaton he chFigure 23.6 Example ofa Food Related Program
for Cancer Pains
Patents sould be advised nt take antodant sp
plement dering ration ements, Raden damage
Cancer ell Ir amend by eypen and anna
"hog to reduce the etenyoesnent
Interventions before and after Surgery Nurtion sp
port betresurgery ny be ential inmate sr)
alocried ptt if deed or 18 days prepe,
2h) bute beret of ut on ppt mt fe weed
‘it it potent ks Pos peste ener eon
[Spreered since hs ls oe for competion snd
a been fund to preserve gu ineity snd mane a
Studies gest ha pene etenn maybe bef
‘when sed peroperatilyn ser malnred patents
Torkead nd neck cancers hich myo ete by ml
tiple malts, propbyac cing abe placement
‘omen ar patents
+ ongoing dearation depo, noes, pin that
Interest the aby ink aeguately
+ sgutcant combs. ining sew station o
‘vee dep
‘role or in patcnts who he compromised cadopa
+ high ik oflong-te salon dds ining
thos atipted to rece lage Belief igh done
radiation othe scan and scent connie ses
fargnne, ns xh and eset ty xe my be ba
‘Gch nator patenting ma cance oper
‘one aes who hive fing ae pen sol be
courage toconsne ods oy they cn swan withsprain Aerts vallowingfnction can oc long
‘Mer tresmeat (pec fer aati sed eaten! and
‘See Chars 1 an 15 fr information on ution
serpy le eres
Interventions for Hematopoietic Cell Transplantation
Inno the sbve pes elated tse ASPEN
‘eommends the fallwing fr ptt ener era
ovr cll enplntaion seh meta conning
+ Nutton apport i appropriate in pets ndegsing
Femotopoet cal raneplatton who ae malourisied
And whe tiated be nal ingest and
aor adequate tet fr prolnged pete oF
Sine When pemeral atone shoul be
{continua eso toes ave sed afer
tomes engament.
Femctoning Gt tat or whom ral takes adequate
+ Mharmacsoge dones ofparetral gutamine may bent
pets unegeing beatport
+ Patent shold ese dtry oaneingreaing fonds
fhntimy pe nection reac sl hing daring
the pr of expense Box 15 Chap 13)
«Nuttin supports ppp for pent underoing
Teatopnat cl transplantation who devbp mere
{sees pat east dsesesecompaniel By poor
‘alma andlor sgncantmalabepon
Determining Nutrlent Requirements Adequate ergy
Intake ceri ia cuenta andor preven
treatment ov disse auocied lo. The flowing cms
eo equtons or the Nin. er eatin ay Be we
{Daktemne the ori node of ane patients”
1 Nonambultry or sodenary adult: 25-30 kal
+ Slight hypermetbol panto thos pains who
tea togun weight ore mbobe30-35 alg
+ Hypermeablc reery stead patents those
‘ek malbsorpion 2s lig oe eer a eed
Adequte poten is important preset of reduce
ete nitrogen bance and meet poten sae
ees Prin eed se epi slevsted those pte
(ih sore dirhea andlor malabsorption Protin needs
(par be clad based on ody weigh the long
+ Nowmalor maintenance protein eed 04-10 gig
Many cancer patients expecially thos nding che
matherpy anos anon can Become darted a
Fld neviecan be called ong he sure formulas wed
formosa aliens witht eal eas ee Cage)
erontent teqlcents fae not ber eebebed or
thos dingo wth ener Us of dal ult
‘amin and mint suplement ht contans “220% ofthe
Dt my be beneficial for ow patents anergpng cheno
therapy andlor ation therapies
Monitoring and Evaluation
Meitring and evan preter shal be tse
the nuuoedagoses and terventos inglemeted to
kes the main prbleme Most kaye and wiht
“hangs wil be meaner nd poten intakes wil be
{eed paleo wile eve, Tolrnce the det should
[cirmine nd any changes nylons Went
Conclusion
acer becuse any tesement options ean sient
Mec spoons nustonal sue Obsiing adequle
ergy. protein, Gude, sami, and mrs and pre
‘ug weight lows, which ocuts ecue n ane
Favens ny help to improve quality of ie for many of
Those undergoing sre no harmaclogi eaten
teancer Resench the arts of grooms and Dg
thorpes should provide a beer anersnding a6 0 the
tng for ance an opel merece pen
Dena Champion MS, RO, LO, CNSC cpa cn Din Art es ac ot an Rh Sr
smh ine Wee bs Cantera On Ste Une
When wos your fist epainc as a tan vetng 2
pen th cance? What was your ath eben on
trcigy
rong ad er is He ag
snr feed ge yarn oe
Seouaton am sey amaze teenth an 8