7/2/2021 Transfusion Reactions - Lecturio

Transfusion Reactions

Transfusion Reactions
Transfusion-related complications occur during or after a blood product is given. These
complications can be classified as immunologic, non-immunologic and acute, and delayed.
Non-immunologic reactions are caused by the transmission of disease in blood products,
and immunologic reactions are antigen-antibody–mediated. Symptoms can range from
mild itching, chills, and urticaria (hives) to high fever, severe shortness of breath, jaundice,
hypotension, or hemoglobinuria. Severe reactions can lead to death.

Last update: November 13, 2020 7:10 am

Table of Contents

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Hemolytic Reactions
Nonhemolytic Reaction
Allergic Reactions
Other Types of Transfusion Reactions

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Hemolytic Reactions

Acute hemolytic transfusion reaction

Etiology:

Type II hypersensitivity reaction→ targets the transfused RBCs

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