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Gallagher2017 - Paliativo
Gallagher2017 - Paliativo
Abstract
Purpose: Evidence has demonstrated the positive effects of music therapy on symptom management for palliative medicine
patients. Previous studies have addressed patient needs, with limited discussion involving the relationship between interventions
utilized to improve symptoms. The purpose of this study was to understand the impact of music therapy sessions; identify
common music therapy goals and interventions and assess their effect; and investigate the effects of gender, age, and type of
cancer on symptoms in patients who experienced music therapy. Methods: This was a retrospective study of data collected
during music therapy sessions. Patients scored their symptoms (pain, anxiety, depression, shortness of breath, and mood) before
and after sessions. Data collected from over 1500 patients included symptom evaluation, goals, interventions, music used, patient/
family reactions, and narratives. Results: Among 293 patients who met all study inclusion criteria, significant improvement in pain,
anxiety, depression, shortness of breath, mood, facial expression, and vocalization scores was noted. In addition, 96% of patients
had positive responses to participating in music therapy. Vocal and emotional were the 2 most effective interventions in improving
symptoms. All 5 patient-reported symptoms improved when the therapist focused on these symptoms as goals. Age, gender, and
diagnosis had no impact on symptom improvement. Conclusions: This study demonstrated the importance of music therapy for
addressing symptoms and behaviors of palliative medicine patients. Statistically and clinically significant effects were noted. The
most effective interventions were identified. More research needs to be conducted to better understand the benefits of music
therapy for palliative medicine patients.
Keywords
music therapy, palliative medicine, symptoms, pain, anxiety, mood
Music therapy interventions have included music-assisted nurses, social workers, physician assistants, chaplains, nursing
imagery, instrument playing, music listening, choosing songs, assistants, music therapists, psychologists, and/or family mem-
music-assisted relaxation/imagery, singing, musical life bers. Data collected was entered into a password-protected
review, song-writing, entrainment, lyric analysis, improvisa- database on a secured drive on the hospital computer. During
tion, and verbal processing.2,5,8,9 These interventions can com- the data analysis stage, the data were downloaded into an Excel
monly be categorized as receptive, recreative, creative, or spreadsheet and deidentified in order to maintain patient anon-
combined, and the patient’s participation level depends upon ymity and confidentiality.
his or her level of energy and symptom management at the time
of the session.2,6,9
Gutgsell et al9 used 1 intervention of live music paired with Sessions/Procedures
autogenic relaxation exercises guided by the MT-BC. Patients
One of the board-certified music therapists (MT-BCs) who
who regularly sang, previously played an instrument, previ-
worked on the palliative medicine unit conducted a music ther-
ously participated in music therapy, or significantly felt music
apy session with individual palliative medicine patients and
played a role in their lives appeared to benefit more from active
any family members present. More than 1 goal may have been
music therapy; however, there was no significant correlation
addressed per session. A variety of interventions were used,
between any of these factors and the intervention that was
with more than 1 being utilized in the majority of sessions.
chosen.5
These interventions were consolidated into 6 main categories:
An active music therapy program has been in place since
music listening, verbal/cognitive participation (eg, music dis-
1994 on the Harry R. Horvitz Center for Palliative Medicine at
cussion, choices, songwriting, etc), vocal participation (eg,
the Cleveland Clinic where music therapy is offered free of
singing and humming), physical participation (eg, playing
charge. A rich database has been collected since the beginning
instrument, clapping, tapping foot, etc), verbal/emotional par-
of the program with our past studies demonstrating that music
ticipation (verbal processing, musical life review, lyric analy-
therapy is effective in improving anxiety, depression, mood,
sis, etc), and music-assisted relaxation. Live, patient-preferred
pain, shortness of breath, facial expression, body movement,
music was utilized in the majority of the sessions. Our experi-
and verbalization.7,8 However, the effects of patient character-
ence and the literature have suggested that patient-preferred
istics, patient goals of music therapy, and music therapist inter-
music has the best effect for patients.15,17
ventions have not been studied in depth relative to these
outcomes. This study was designed to address this gap.
The objectives of this study were (1) to describe patient
characteristics, patient goals, and interventions used by the
Data Collected
music therapist; (2) to assess the impact of music therapy ses- Data collected on all patients who agreed to participate in
sions on outcomes; and (3) to identify which patient character- music therapy was included in the music therapists’ clinical
istics, goals, and interventions had an effect on outcomes. notes in the patients’ medical records and was documented in
Patient-reported outcomes included changes in pain, depres- a computerized database on a secured drive utilizing FileMaker
sion, anxiety, shortness of breath, and mood before and after Pro (FileMaker, Inc, Santa Clara, CA, USA).18 This clinical
the music therapy session. Therapist-reported outcomes database was created prior to the implementation of electronic
included changes in facial expression, body movement, and medical records. Data included the standardized music therapy
vocalization. assessment, elements of the standardized music therapy clinical
note, patient-related information (Table 1), patient goals for the
music therapy session, interventions used by the music thera-
Methods pist, symptom evaluations from the patient, behavioral evalua-
tion from the music therapist, music used, patient and family
Participants member reactions, and narratives. Specifically, patient-related
This study was approved, and a waiver of informed consent information included age, gender, diagnosis, reason for refer-
granted, by the institutional review board at The Cleveland ral, and referral source. Symptom evaluations from the patient
Clinic. All procedures followed were in accordance with the included pre- and postsession severity of pain, depression,
Helsinki Declaration of 1964 and its later amendments or com- anxiety, and shortness of breath, all of which were rated on a
parable ethical standards.16 Patients included those admitted to 0- to 10-point scale and mood which was rated on a 0- to 4-
the Horvitz Center and those followed by the Palliative Med- point scale based on the Rogers Happy/Sad Faces Assessment
icine consult service on other acute inpatient units at the Cleve- Tool.19 The music therapist scored 3 behavior variables on a 0-
land Clinic. This was a retrospective study of data obtained to 3-point scale before, during, and after the music therapy
from music therapy sessions with these patients held between session (facial expression, body movement, and vocalization)
September 2000 and May 2012. These data can be accessed as based on the Nursing Assessment of Pain Intensity20 and the
necessary by the authors upon request. All palliative medicine Riley Infant Pain Scale.20 For all of these assessments, higher
patients were eligible to receive music therapy sessions. They scores represent worse outcomes. The outcome measures were
could request it themselves or could be referred by physicians, used in prior studies, but they have not yet been validated.
Gallagher et al 3
Results
Study Inclusion Patients were primarily female (67%), with a median age of 61
The music therapy database contained 5970 music therapy ses- years and a cancer diagnosis (93%; Table 1). The most com-
sions from 1570 patients. Inclusion criteria for this study con- mon diagnoses were lung cancer (16%), hematologic cancers
sisted of patients being at least 18 years of age and having at (14%), breast cancer (13%), and gastrointestinal cancer (12%).
least 1 patient-reported rating of pain, depression, anxiety, The top 5 referral sources included social workers (32%), phy-
shortness of breath, or mood before and after the music therapy sicians (18%), physician assistants (13%), patient availability
session. Only the first session with data was included in this (12%), and nurses (11%). In order of frequency the top 5 rea-
study for patients who had more than 1 session. This inclusion sons for referral included enjoyment (23%), anxiety, (16%),
resulted in a total of 547 patients. Among these, 293 patients pain (13%), depression (12%), and support (7%).
had complete data on all primary outcomes measures and were Of the 287 who identified their preferred style of music, 37
included in the data analysis. different styles were identified. The top 5 styles of music were
4 American Journal of Hospice & Palliative Medicine® 00(0)
gospel/religious (19%), various/any (16%), country western Table 2. Goals of Music Therapy (Ordered From Most to Least
(11%), semiclassical/ classical (8%), and jazz/Frank Sinatra Common).a
(8%). Other styles included rock various decades, musicals, Goal met
and hip hop. In addition to the religious music mentioned ear-
lier, Jehovah Witness and Jewish music were also utilized. Goal Yes Yes No Unknown
Various ethnic music used included polkas, Irish, Native Amer- Improve/maintain mood
ican, Brazilian, Spanish, and Filipino. N 243 200 40 3
Twenty total goals were identified in all patients (Table 2), % 82.9 82.3 16.5 1.2
with individual patients having 1 to 6 goals (Table 1). The Decrease perception of pain
N 164 93 68 3
music therapist documented whether goals were met, but if
% 56 56.7 41.5 1.8
unknown, they were considered to be unmet. One to 5 inter- Decrease anxiety
ventions were utilized per session, with at least 1 or 2 being N 141 111 29 1
utilized in 71% of sessions (Table 1). % 48.1 78.7 20.6 0.7
There were statistically significant reductions (improve- Decrease depression
N 103 78 25 0
ments) in pre- to postsession mean scores for all measurements % 35.2 75.7 24.3
except body movement (Table 3). However, the percentage of Decrease shortness of breath
patients reaching the clinical significance threshold ranged N 93 56 36 1
from 0.7% (body movement) to 66.2% (mood; Table 4). % 31.7 60.2 38.7 1.1
Self-expression/emotional release/emotional processing
Ninety-six percent of patients had a positive verbal response
N 85 83 1 1
to the session, with the remaining 4% having an ambivalent or % 29 97.6 1.2 1.2
no verbal response. Decrease stress/provide distraction
Twenty variables were included in multiple linear regres- N 55 52 3 0
sion analysis to determine their effect on change in each of the % 18.8 94.5 5.5
Increase participation/interaction, leisure skills, mobility
8 scores (Tables 5 and 6). The most improvement in pain, N 54 51 3 0
depression, anxiety, shortness of breath, and mood was seen % 18.4 94.4 5.6
among patients who had each of these goals for their music Relaxation
therapy session. In addition, utilizing a vocal intervention also N 47 46 1 0
% 16 97.9 2.1
improved depression, anxiety, and mood while a verbal/emo- Comfort and solace/end of life issues/anticipatory grief
tional intervention improved mood. Facial expression signifi- N 34 34 0 0
cantly improved when vocal, emotional, and physical % 11.6 100
interventions were used. Vocalization significantly improved Enjoyment
when a verbal/emotional intervention was used and when dis- N 19 18 1 0
% 6.5 94.7 5.3
traction was a goal of music therapy. No variable was associ- Assessment
ated with body movement. The demographics and cancer N 12 11 0 1
diagnosis had no impact on outcomes. % 4.1 91.7 8.3
Increase positive family interaction
N 8 7 1 0
Discussion % 2.7 87.5 12.5
Increase coping skills: emotional, physical, combination
Music therapy was found to improve pain, anxiety, depression, N 7 7 0 0
shortness of breath, mood, facial expression, and vocalization % 2.4 100
at a statistically significant level (P < .001). The variables with Increase acceptance of music therapy/music therapist
N 7 7 0 0
the highest percentage of patients reaching a clinically relevant % 2.4 100
improvement were mood, vocalization, and facial expression. Decrease nausea
These results were consistent with our previous findings.7,8 N 6 4 2 0
Although results were positive overall in addressing numer- % 2 66.7 33.3
Increase cognition/orientation/decision-making/alertness
ous goals with various interventions while attempting to N 6 6 0 0
improve 8 variables, some results were more positive than % 2 100
others. Based on the findings it can be concluded that vocal Increase self-esteem
and verbal/emotional interventions have the most impact on N 3 3 0 0
improving symptoms. It was found that mood, pain, anxiety, % 1 100
Decrease restlessness
depression, and shortness of breath all improved when the MT- N 1 1 0 0
BC specifically focused on these symptoms as goals. % 0.3 100
In addition, the music therapists on the palliative medicine Increase/maintain comfort (physical)
unit were often called in to assist with patients who were hav- N 1 1 0 0
% 0.3 100
ing extreme pain or who were having difficulty expressing their
emotions. The music therapist was often seen as someone in a
N ¼ 293.
Gallagher et al 5
Table 3. Continuous Assessment of Score Changes.a Table 4. Categorial Summary of Score Change.a
Table 5. Multiple Linear Regression Models for Pain, Depression, Anxiety, and Shortness of Breath.a
Demographics
Age 0.005 .35 0.003 .79 0.003 .64 0.007 .23
Female 0.03 .86 0.2 .34 0.07 .73 0.13 .5
Diagnosis
Cancer 0.08 .8 0.17 .65 0.31 .41 0.1 .78
Interventions
Listen 0.5 .24 0.6 .25 0.4 .43 0.45 .34
Cognitive 0 .99 0.49 .024 0.07 .74 0.15 .44
Vocal 0.16 .41 0.59 .015 0.53 .025 0.08 .7
Emotional 0.02 .95 0.41 .15 0.1 .72 0.39 .12
Physical 0.14 .55 0.01 .98 0.19 .52 0.03 .92
Relax 0.08 .82 0.58 .19 0.39 .36 0.31 .43
Goals
Mood 0.03 .89 0.12 .67 0.09 .74 0.19 .44
Pain 1.11 <.001 0.22 .31 0.41 .046 0.08 .66
Anxiety 0.05 .77 0.2 .36 1.98 <.001 0.27 .17
Depression 0.32 .07 2.33 <.001 0.05 .82 0.19 .34
SOB 0.27 .11 0.17 .41 0.22 .29 1.62 <.001
Self-expression 0.04 .85 0.57 .041 0.19 .48 0.4 .11
Distraction 0.03 .87 0.1 .68 0.21 .39 0.14 .54
Participation 0.35 .14 0.59 .046 0.4 .16 0.08 .75
Relaxation 0.03 .88 0.45 .09 0.04 .87 0.17 .49
Comfort 0.12 .65 0.37 .25 0.27 .38 0.17 .55
Enjoyment 0.52 .1 0.44 .26 0.43 .25 0.07 .84
Abbreviation: SOB, shortness of breath.
a
N ¼ 293.
Demographics
Age 0.001 .79 0.003 .19 0 .87 0.004 .1
Female 0.06 .6 0.03 .64 0.01 .6 0.04 .58
Diagnosis
Cancer 0 .99 0.12 .39 0.01 .54 0.08 .57
Interventions
Listen 0.11 .71 0.2 .27 0.01 .76 0.06 .73
Cognitive 0.06 .62 0.18 .02 0.01 .2 0.31 <.001
Vocal 0.4 .004 0.19 .028 0.02 .19 0.04 .67
Emotional 0.39 .015 0.22 .024 0.02 .16 0.2 .049
Physical 0.18 .28 0.3 .004 0.01 .72 0.1 .37
Relax 0.27 .29 0.13 .42 0.01 .84 0.13 .41
Goals
Mood 0.93 <.001 0.08 .4 0.01 .36 0.14 .15
Pain 0.08 .53 0.08 .27 0.02 .09 0.11 .15
Anxiety 0.01 .96 0.03 .67 0.02 .13 0.03 .72
Depression 0.11 .38 0.03 .69 0.01 .46 0.04 .57
SOB 0.04 .75 0 .97 0.01 .43 0.06 .45
Self-expression 0.19 .24 0.02 .85 0.02 .1 0.03 .78
Distraction 0.02 .86 0.07 .41 0.02 .16 0.19 .039
Participation 0.17 .32 0.01 .9 0.01 .42 0.16 .13
Relaxation 0.13 .41 0.09 .34 0.02 .09 0.01 .91
Comfort 0.05 .77 0.01 .93 0.01 .68 0.09 .43
Enjoyment 0.1 .65 0.11 .41 0.01 .63 0.14 .3
a
N ¼ 293.
Gallagher et al 7
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Authors’ Note
sional needs of hospice patients and families. J Palliat Care.
The authors had full access to all of the data in this study, and we take
2001;17(3):161-166.
complete responsibility for the integrity of the data and the accuracy of
12. Krout RE. Music therapy with imminently dying hospice patients
the data analysis.
and their families: facilitating release near the time of death. Am J
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Acknowledgments
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The authors wish to acknowledge Dr Francois Bethoux for his support music therapy care. In: Dileo C, Loewy JV, eds. Music Therapy
and help; Maria Jukic for her support; and the various music therapists
at the End of Life. Cherry Hill, NJ: Jeffrey Books; 2006.
and music therapy interns who conducted the music therapy sessions
14. O’Callaghan CC, McDermott F, Michael N, Daveson BA, Hud-
for our patients.
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music’s relevance for adults living with life-threatening cancer
Declaration of Conflicting Interests
diagnoses. Support Care Cancer. 2014;22(4):1037-1047. doi:10.
The author(s) declared no potential conflicts of interest with respect to 1007/s00520-013-2059-1.
the research, authorship, and/or publication of this article. 15. Hogan BW, Silverman MJ. Coping-infused dialogue through
patient-preferred live music: a medical music therapy protocol
Funding and randomized pilot study. J Music Ther. 2015;52(3):420-436.
The author(s) disclosed receipt of the following financial support for doi:10.1093/jmt/thv008.
the research, authorship, and/or publication of this article: The authors 16. World Medical Association. WMA declaration of Helsinki: ethi-
wish to thank The Kulas Foundation and the Jack Belcher Music cal principles for medical research involving human subjects.
Therapy Fund for financial support which made this research possible. 2017. https://www.wma/net/en/30publications/10policies/b3.
Accessed February 22, 2017.
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