THUYET DUgE LY DE THE CO 90 CA i AU TRAE NGHIEM VA 30 CAU DI SAL PHAN 1: CHON My Phat bidu doe a> Lit Khang sinh thug lk be Dung str dang tuo C6 higu Ive cao tren o &- Gy ire ché cytochrome P50 eC y hGi ching ngudsi do (Re a 2 Kinin nh nto sau dy hg ig ees pei S dinanycad? Ncsianns @) d- Chloramphenicol Pry ate! iy d-Suepumyein—siiegn nth ff ‘¢- Doxysyelin — ing nhay cam vii anh séng Y DUNG NHAT boi da, agt im ao, da dang, bao gdm: sem fink mach, ub ‘Gram () higu kh im tang nbng dé theoplylin ‘Man Syndrome) khi tiem th meh VK teen Bacterpides fragilis aay tic dung phy nto sau 48 ké0 dai khong QT hudn duimg rudt (dana gy) Gee ieee © Amikacin, 1 Raseonam \Clindamycin - Cefsulodin 'b- CeftazidimY Khong diing vi pefloxacin: ci dich no thy ———— Duge dio thai cha yeuQua thar Cac khang sinh nao sau day cé thé chi dinh trong nhiém tring sinh dye do Chlamydia: c Gentamicin Os spectinomycin i 6 b a- Doxyeyelin b- Lincomycin d- Ceftriaxon éu luc digt khudn cia cdc aminosid duge xép theo thir thy nhur sau a. Streptomycin < dibekacin 6. Tac déng cla khéng sinh nao sau day ©6 higu lye digt Khun phy thuge nding dO: ® Streptomycin Goring coicch) ¢- Piperacilin e- Ampicilin + Cefuroxim {gu lye cao trén vi khudin MRSA, ngoai tir: sac e- Quinupristin/dalfopristin. b- Erythromycin 10. Céc khang sinh sau day 06 hi 1 a- Linezolid e-Daptomyein | b- Vancomycin Meropenem Jam ting d6¢ tinh trén than: ; ; c- Cefotaxim + metronidazol e- Clarithromycin + amoxicilin 1 11. Phdi hop nao sau day la Vancomycin + gentamicin b- Ampicilin + sulbactam Ma dé 124 d- Ciprofloxacin + cefixim12. Thudc~eo ché i déng nao sau day ld ding: f Ceftriaxon - ite ché téng hop protein cia vi khudn d- Clindamycin - te ché men beta lactamase & Tazobactam - te ché téng hop acid nucleic e Ga icarcilin - thay d6i tinh thim mang bio Levofloxacin - tre ché men topoisomer tuomg 3. Cephalosporin dy roi loan dong mau: & Cefaclor. e- Cefuroxim bCefazotin 14°Suttamid — sir ng tr Higu no sau day khéng hop | Sulfadoxin aoe viém nao do toxoplasma 4- Sulfacetamid — nhiém tring mit + Sulfaguanidin — nhiém khudn duong rudt ¢> Sulfasalazin —viém loét két tring ulfadiazin bac —nhiém tring tai vét bong an lu ¥ nhiing diém sau day khi str dung khéng sinh nhom aminosid, ngoai trix: Hiéu chinh lieu 6 bénh nhan suy gan - Khéng trén chung 1 4ng tigm véi cdc cephalosporin & Cain theo doi ndng do thud ‘trong tr ligu d- Khong siz dung lign tuc va kéo di (P10 nga: © Doc tinh trén than ting lén khi phéi hop véi thudc loi tigu thiazid 16. Phat biéu nao sau day ding véi vancomycin: a- Higu lire eao trén vi khuan E.coli tiét ESBL ‘be Chuyén héa 6 gan, dio thai chi yéu qua mat p s La khdng sinh tra chon dau tién trong didu tri viém rugt két do C. difficile, Oo ‘Can tiém tuyén tinh mach chm trong dir phéng nhiém tring vét m6 e- Khodng an toan rong, khong can theo nng 49 thudc trong trj liéu 17. Phat biéu nao sau day ding v6i khang sinh nhém quinolon: ite is ne i; Ciprofloxacin higu lye cao trén S, preumonia i mcrae we ne ce oa @nortoxacin phan bd kém & m6 = AO) lam tang sinh kha dyng, id nalidixic « tren. ‘ofloxacin 2 ee aaa nai hgp Quinupristin + Dalfopristin: ; ‘gp protein cia vi khudn do gin vao tiéu don vj 30S cia ribosom +:dalfopristin 1a 3:7 niio thy su chinh liéu & ngudi suy thin do Treponema pallidum e- Saquinavir= Acyclovir °6 the dung 6 dang triphosphat, ago ri b- Zidovudin ¢-Emtricitabin 23. Phat bidu nao sau day khong ceete acyclovir £ Hoot tinh tr cytomegalovirus kém hon eoaneny b- Hap thu kém 5 khi ding duéng uéng i a qui cao Khi didu tr Herpes man tinh & Phot hop voi amantadin ety chimg bubn ned ning S Bénh zona uéng liéu thip hon so véi bénh m Op 24. Chon thude 6 te dong trén i sinh tring s6t 6 thé ng tai gan A. Chloroquine Quinidine : digu tri tiet can, (2) giée nigudi du lich dn ving dich. Chon ® (1), 2), GB). B. (1), 2), (4) D. a is ae de eho 27. Lira chon wu tién 46i véi sén Id gan A. Mebendazol 1 B, Albendazol 28. Cho céc co ché dé khéng i protein dich téc dong, Chon 16 hgp co ché. A. (I), 2), 3) B. (1), (3), (4) ‘D) 29. Chon phat biéu sai vé Pyrazinamid . (A) Pyrazinamid c6 nhiéu co ché téc dong . Pee, B. Enzyme ciia vi khudn dong vai trd quan trong doi v6i host tinh pyrazinamid 30. Chon dich téc dOng dting cia Dapsone A. Dihydrofolate synthase C. Thy B. Dihydrofolate reductase 31. Chon phat biéu ding ve @ Dot bien gen KatG 1a mot trong nhimg nguyén nhan dé khéing INH B. INH tiée dong tte ché téng hgp RNA théng qua ire ché RNA polymerase tnudng ki khi, pH thaip D. INH chi cho téc d6ng kiém khudn : é E. Y nghia phdi hyp INH trong phéc d6 nhém vao trac khudn chuyén hod cham Chon phat biéu sai vi A. Caspofungin tre ché tong hop 1,3-B-d-glucan B. PhO bao g6m Candida, Aspergillus vi Cryptococcus neoformans C. Dé khing thutmg do dét bién tai glucan synthase D. Hap thu durdmg uéng kém nén chi yeu ding LV E, Cén higu chinh liéw 6 46i tong bénh nhan suy gan. ee a ; oa -RhOng thuge nt a : ene As C- Ue ché Na‘/K"/2Cl" a : é yrter ykenb Na° ~ Doi khang véi aldosteron sympor fete tate =Co ché téc dung nao dirdi day 1a khong hop ly: lesertid ~ Téc dng twong ty ANP ramrinon - Ue ché PDEs = CC. Levosimedan ~ Tang tinh nhay cim ca co tim voi Ca? D- Dobutamin ~ Kich thich By va Bo-receptor E- Bumetanid - Uc ché NKCC2 : 3, Diéu nao du6i day khéng phii la dip img khi hoat hoa AT; receptor: Dien, « @Giam tiét aldosteron B-Comach _ C- Tang hoat tinh giao cam D- Lara gitt mudi nude E- Tang sinh 44, Bidu nao dudi day khOng phai la dgc tinh ctigFemikiren} 4 airs Uc-ché angiotensinogen C- Uc ché phi dai tim E- Gidm hoat tinh giao cam 45. Thude nao dudi day khéng thuge nhém thudc 1am giam huyét 4p do tae dng trén trung tam van spach BD Reserpin B- Metyldopa -Clonidin D- Guanabnez E- Guanafacin 46. Mannitol cé thé sir dung trong céc truémg hgp sau, ngoai trir; 6 nig : B- Gia ap lye n6i so C- Gidm ap lye nhin edu D- Thigu nigw/dyr phong suy than ep E- Ng6 dc thuéc 47. Acetazolamid thé hién téc dng nao duéi day A-Gidn mach 3 Chim nihip tim - Gidm phéng thich D- Tang thé tich tng Ue ché tai hap thu NaHCO3 noradrenalin Wa dé 104 a dé 124 4thud ent ‘VOi aldosteron KEM sie th Ane : Be Men i dong try tibptrén he RAA toprotol Vv; TE yc dang gE ianania C-Aliskiren V Benin Label Be Bean toe oH din rong hb mkt fp A she MTS khong 06 de uate moo: ng ngin ‘tinh ndo dudi day: ae B Chen kénh Ca wénmach¥,— c-Thute hd ne2 v é eaalapail to dy gidin mach ngoai bien / site edn mech eat etre {rj ting huyét dp 1a khong hop ly: D- Khong higu Ie néu hoat tinh renin thip én baroreceptor 31 b) Tang thé tich ty © Te hn do emi Olricding « egttoProlol Khéng c6 tic dong no sau day: Gay co that phé quan , Giam hip tim q Giy tiét prostaglandin -A- Tang phan suit 'B- Chon lua cho bénh nhan suy tim km rung nhi V“ Gidm tien tai Chon la wu tién cho suy tim 46 IL E- Taing thoi ky tro Fe 57. Co ché tac dung cia thudc tri loan nhjp nao duéi day 1a sai: ‘A- Amiodaron ~ Chen kénh K* D- Disopyramid ~ Chen kénh Na+ - Sotalol ~ Chen beta-adrenergic E- Digoxin: tre ché Na'/K*-ATPase @Quvenos — Kich hoat kénh Ca’, chen kénh K* 5%. Ranolazine duge xem la te d6ng trén pha ndo cita thé hoat dng: ‘A- Pha 0 B- Pha | eae (Ops 2 D-Pha 3 E- Pha 4 I 59, Bénh nhan A cé nhip xoang la 145 nhip/phiit. Thude ndo sau day nén wu tién chi inh cho bénh nhan. 4- Amlodipin B-Flecainid C- Metoprolol ae D- Dae E- Nebivolol BO Rea te 0. Cae thude duéi day thuéng duge chi dinh trong diéu Wishing Hie Bons tri: Amiodaron B- Metoprolol TEHUTO D- Nadolol E- Atenolol 61. Thude nao dudi day c6 tac dOng tre ché hap thu cholesterol 6 rug: A- Atorvastatin B- Fenofibrat (CE zetimib D-Nia E- Colesevelam Ma dé 124 elC- Dau co . sori ‘trong lt Saas ti a ene F 64 TH Une dive cho Sh ala cohn7 Tica se . lim an hoya han via duge phiu thugt gin day A> Alteplase «din xufi cd alteplase nhumg Typ dai hom va chuyén bigttrén fibrin hon: eee 8) ieee 2 C- Urokinase A ATi “oo D- Enoxaparii C- Fondaparinux ne Pudi moat any a were eo 4 ae Diing trong tr liu kéo dai cho cde trutmg hgp thay eh The do, ae fe nee ap rs te (OTe dung ching ame q See tg neh ek sa ving Sos totes at bicu. fees ie ga nao sau day khdng ding ve tée d6ng @Phite hop hormon-thu thé hot hoa enzym ad B. Adenyl cyclase xic tac phan img tao AMPe tir. C. AMPc hoat hod mét chudi enzym protein | D. Enzym dap img véi AMPc khdc nhau gitfa cac E. AMP bj bit hoat thinh $’AMP duéi téc dng cta phosphodiesterase 68. cease Taeota A. Monoiodotyrosin riiodothyronin: E. Thyroglobulin B, Diiodotyrosin Tetraiodothyronin 69. Co. ehe tic dung nao sau diy la cba tia B?- iit iod tir méu vao tuyén gidp Ue ché gain iod vao tyrosin é phong thich hormon tuyén gidp Gms hy té bao tuyén gidp c thyroid peroxydase 70. Chi dinh nao sau day 1a eda hormon tuyén gidp? Uu nang tuy D. Nhiém ddc tuyén giap Bucu gidp cé nh E. Suy tim, logn nhip tim C. Chuan bj phau thu: 71. Thuéc levothyroxin khong cé téc dung phy nao sau day? A. Dau th ngye Tang can E. Nhite dau Gay non methyl thiouracil khéng cé chi dinh nao sau A. Bénh Grave Boxing gidp kém theo viém gan B. Phoi hop khi ding 1°’ phéng xq BE. Buéu age tuyén giap C. Chuan bj phdu thuét tuyén giép insulin khong durge chi dinh trong trugng hgp dai théo dutmg typ 2 nao sau day? voi cde thudc ha duémg huyét khac ¥ if glucose lic d6i trén 15,0 mmol/l ng dudmg hu: dc ¢6 ceton mau va ni loac hn mé do dai thao duéng Ma dé 124@ glucagon-like peptid-1 (GLP-1) bao nhieu %? 7 €.30% E50% = ? D. 40% iston dé trénh thai sau giao hop thi cn ding liéu ndo sau day? C.100 mg E. 1000 me A 200mg 76. Chi dinh nao sau day khong aes Hi hb bp +k poner I ES TES EL ata lee ouaee iu tri chimg béo phi nguyén phat . PhOi hyp dig pee” C. Dieu tri thay thé trong giai doan man kinh * te 77. Testosteron téng hgp nao sau day duge ding t aoe hu? 3 A. Diethyl stilbestrol C. Mety B. Testosteron propionat . Trong truéng it md ‘yiém glucocorticoid ee ‘ © @Dexamethason nhéa nuée va chit dign gidi duoc img dung tren C. Desoxycorticosteron, E, Hydrocortison B. Aldosteron D. Cortison pat 81. Glucocorticoid duge chi dinh trong cdc trrong hgp sau, ngoai tri: A. Viém tim do thép khép_ ic ye ee tiép xitc B. Lupus ban 46 D. Bénh collagen ; 3 Pia bie nao sau day vé nhém khang thy thé histamin H2 khéng ding: a, Hap thu tot quaduéng uong 4 %.) Cé thé uéng chung véi cdc thuée nhém antacid 5 Cimetidin la thude cé tac dung yéu va nhiéu tée dung phy nhat d. Co thé gay hign tugng no héa tuyén vi tem thoi ¢, Lam ting téc dung cla thuéc khang ding $3. Khi ding lau dai PPI, thude khéng gay tc dung phy mio sau day: a, Giam hap thu Fe, Ca, Mg, B12 Khé tigu G&D Tang nguy co loding xuong, gay xuong e) Ung thy da day ¢. Tang nguy co nhiém tring (CAP, C. difficile, Salmonella, Campylobacter) 84. Thudc dieu tr lo¢t da day nio sau day khong can giém liéu 6 bénh nhan suy than: Maen bao Cansoprezol e. Bismuth subsalicylat p Neie ey 4. Sueralfat v F Ze tie a bom proton nao c6 mgt phan duge chuyén héa khong qua con durong cytochrome: . Omeprazol c. Pantoprazo) e. Eso b, Lansoprazol Rabeprazol meprazo} re vs ie dung diét Khuan nho ting ning 6 khang sinh tron, . Natri benzoat B. Guaifenesin Peon d. Terpin hydrat @zen Jao dang tién trién ig nhu m6 phéi la dac diém eva: e. Codein ie,» Tang hoat tinh eta ~ Ueché hoat tinh . Diéu naoGiém Gn, ba tree td e tiep » ie a@ Dring? "2 phibu tra toi tric nghi¢m voi: ». Sai a Oscltamivir » Fi eee Shi inh ‘anid R Aga la dang titn pease oa Herpes simplex khéng neyslovs ae 6 thé gay chimg bun ng ‘ing ih phéi hop v6i zidovudin » PhOi hop ameiceit 28 tu chay do Kich thet nha a - Doxyeyclin a ne seta viém phi - Lumafantrine lim ken eee 2001 . Ethambutol 6ng 6 I9i lau dai cdia hydrocl 12 103. Captopril v6i T1/2 ngén, téc déng nhanh na Phe ae e ngan, tac dng nhanh nén 104. Bén canh téc dng lam giém nhip tim va { tac déng chen al-adrenergic receptor. 105. Nitroglycerin er Iya dau tién cho cant, 106. Labetalol la thudc c6 thé chi dinh cho tang Z ete ‘ 107. M6t trong nhtmg nhuge diém ise furosemid 18 higu lye loi tiéu 1¢ thudc vao chite nang than. 108. Néu bénh nbn tang huyét 4p 46 2 thi vige digu tri nén bit dau bing phéi hop thudc. 109.Khi phi hop spironolacton vi ACEI, can phai thiin trong do gay giam K” huyét. 110. Verapamil téc dong wu tién hon trén mach méu so voi trén tim. 111. Tée dong gay phi mach ciia ACEI chi yéu ld do phan tmg dj tg. 112. Agatroban c6 tac d6ng khang vitamin K manh hon warfarin. bs ' 113. Dan chit thionamid dirge wu tién Iya chon cho phy nf cé thai lmethimazol 114, Glucocorticoid cd thé gly kich thich, géy sang khodi, qua mite din én thao cudng Mi Vin & 115. Insulin duge xem 1a bj dé khéng khi khdng 6 tac dung ha dudng huyét sau 2-3 ngay sit dung voi liéu 100 UW/ngay 116. Glipizid e iy téc dung phy ndi mén da, ngira, budn non, non, thiéu mau bat san. 117.Zileuton 1a thude tr hen suyén theo co ché d6i khéng leucotrien trén leucotrien D4 receptor 118. Ketotifen ld thudc khang histamin ty hen suyén theo co ché tte ché phong thich leucotrien, histamin tir céc duéng bio bao bach cau wa base 119. Cae thuoe ite che bom proton c6 thoi gian ban hiy kéo dai 120, Sucralfat c6 the sir dung chung v6i cde antacid