Opioid Antagonist

Naloxone naltrexone
•
,
and
nlalmefene are
µ Receptor
action at
Antagonists with
significant blocking K and

S Receptors also .

Alvimopan &
Methyl naltrexone are
peripheral opioid
antagonists .

Actions :

action
These have no in the absence
of agonists but
•

when administered
promptly reverses the
opioid effects
IV.

They can
percipitate withdraw
symptoms in
opioid
dependent subjects .

Uses :

• Naloxone -

Drug 7
choice
for Acute Opioid Poisoning .

Naltrexone -

i. Maintenance
drug for Opioid Poisoning .

ii. Prevent
Relapse after opioid de addition .

Iii , Decrease
craving in chronic Alcoholics .

Treatment
• Naltrexone +
Bupropion
-

7
Obesity .

② Med Notes (www.mednotes.in)

☒
full Med Notes : med notes ebooks .

company
. site

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