‘Proteos’ in Greek meaning primary.

Important protein that carry out a

lot of functions in our body.

Protein made up of :
PROTEINS
<MK
1. = monomer or simplest form of protein.
2. peptide = dimer of protein formed from the condensation of
two molecules of amino acids.
3. peptide = polymer of proteins formed from the
condensation of many molecules of amino acids.

AMINO ACIDS
Draw and label the general structure of an Describe the general structure of an amino
amino acid acid

A compound with an group (NH2),

a group (COOH) and a chain
(R group) ALL attached to a central alpha
carbon.

There are 20 different amino acids, all differing at their chain. However the side chains can
be grouped into 4 distinct groups based on similar properties creating 4 groups of amino acids.

Name of the Group

Characteristics Characteristics Characteristics Characteristics

Rank Rank Rank Rank

DIPEPTIDE
Formation of dipeptide

Breakdown of dipeptide

POLYPEPTIDE / PROTEINS
Polypeptide A

1. How many amino acid residues in the polypeptide above? .

2. Circle and label the amino and carboxyl terminal of Polypeptide A. How many amino and
carboxyl group left in the Polypeptide?
a. Number of amino group left : . Now known as
b. Number of carboxyl group left : . terminals

3. Highlight and label all the peptide bond in the Polypeptide above.
4. Circle and label all the side chains in the Polypeptide above.

BASED ON LEVEL OF ORGANIZATION

1. 2. 3. 4.
BASED ON STRUCTURE

Name of the group

Example
Presence of tertiary
structure

Shape and arrangement of

the polypeptide chain (s)

Solubility in water
BASED ON COMPOSITION

Name of group

Cosmposition Does not contain any other Contain other substances. For
substance. Just purely amino example lipid forming lipoprotein
acids. and carbohydrate forming
glycoprotein.

Example Albumin

FACTORS AFFECTING PROTEINS

Function of a protein depends on it conformation. The conformation of a protein is maintained by

the various interactions within the protein molecule.

Name of interaction/ bond How the interaction formed

Between the backbone

Between the side chain of different amino acid

residues in the polypeptide chain

Therefore, when a protein encounters

these factors, proteins will DENATURE

Bonds/ interactions affected are:

Too high temperature

Bonds/ interactions affected are: